Synthetic Fibrinolytic/thrombolytic Agents

Synthetic Fibrinolytic/thrombolytic Agents PDF Author: Kurt Nikolai Kaulla
Publisher: Charles C. Thomas Publisher
ISBN:
Category : Medical
Languages : en
Pages : 518

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Book Description

Synthetic Fibrinolytic/thrombolytic Agents

Synthetic Fibrinolytic/thrombolytic Agents PDF Author: Kurt Nikolai Kaulla
Publisher: Charles C. Thomas Publisher
ISBN:
Category : Medical
Languages : en
Pages : 518

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Book Description


Neurocritical Care Pharmacotherapy

Neurocritical Care Pharmacotherapy PDF Author: Eelco F. M. Wijdicks
Publisher: Oxford University Press
ISBN: 0190684747
Category : Medical
Languages : en
Pages : 353

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Book Description
Neurocritical Care Pharmacotherapy: A Clinican's Guide is a practical, succinct but comprehensive pharmacy handbook provides up-to-date clinical guidance on the effective selection, prescription, and usage of neurocritical care drugs for patients with acute neurologic illnesses. The treatment of the critically ill neurologic patient is often difficult, specialized, and includes drugs infrequently used in other intensive care units such as antiepileptic drugs, osmotic agents or acute immunotherapy such as intravenous immunoglobulin and plasma exchange. This text discusses choosing the right combination of drugs; how to correctly prescribe and administer the drugs; how to monitor drug efficacy and side effects; how neurocritical care drugs interact with other medications; and comprehensive coverage of current treatment options. Key Feature of this Manual Include - A brief discussion of the basic pharmacology of each neurocritical drug, with an emphasis on how to select and use these drugs in multiple clinical contexts. - 150 drugs accompanied by a diagram for quick comprehension and drug administration guides. - Unique blending of expertise of neurointensivist with a critical care pharmacist to provide a vital resource for both specialities - References for further reading that are oriented toward utility in clinical practice.

Laboratory Hematology Practice

Laboratory Hematology Practice PDF Author: Kandice Kottke-Marchant
Publisher: John Wiley & Sons
ISBN: 140516218X
Category : Medical
Languages : en
Pages : 777

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Book Description
Expertly edited and endorsed by the International Society for Laboratory Hematology, this is the newest international textbook on all aspects of laboratory hematology. Covering both traditional and cutting-edge hematology laboratory technology this book emphasizes international recommendations for testing practices. Illustrative case studies on how technology can be used in patient diagnosis are included. Laboratory Hematology Practice is an invaluable resource for all those working in the field.

Case-Based Clinical Cardiology

Case-Based Clinical Cardiology PDF Author: Majid Maleki
Publisher: Springer Nature
ISBN: 1447174968
Category : Medical
Languages : en
Pages : 480

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Book Description
This book comprehensively covers a range of pathological cases in clinical cardiology. Chapters are case focused and detail how a patient is diagnosed and treated in a step-by-step format. A range of engaging video clips enhances the reader’s appreciation and understanding of how to apply these techniques into their day-to-day clinical practice with special focus on congenital heart disease diagnosis and management. Case-Based Clinical Cardiology presents a range of clinical scenarios across all cardiology disciplines with a particular focus on echocardiography, electrocardiography and cardiac catheterization. Therefore, it is an ideal resource for both the novice and experienced cardiology practitioner seeking an up-to-date selection of cases to test their knowledge.

Therapeutic Enzymes: Function and Clinical Implications

Therapeutic Enzymes: Function and Clinical Implications PDF Author: Nikolaos Labrou
Publisher: Springer Nature
ISBN: 981137709X
Category : Science
Languages : en
Pages : 388

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Book Description
Therapeutic enzymes exhibit fascinating features and opportunities, and represent a significant and promising subcategory of modern biopharmaceuticals for the treatment of several severe diseases. Research and drug developments efforts and the advancements in biotechnology over the past twenty years have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of both rare and common disorders. The introduction and regulatory approval of twenty different recombinant enzymes has enabled effective enzyme-replacement therapy. This volume aims to overview these therapeutic enzymes, focusing in particular on more recently approved enzymes produced by recombinant DNA technology. This volume is composed of four sections. Section 1 provides an overview of the production process and biochemical characterization of therapeutic enzymes, while Section 2 focuses upon the engineering strategies and delivery methods of therapeutic enzymes. Section 3 highlights the clinical applications of approved therapeutic enzymes, including aspects on their structure, indications and mechanisms of action. Together with information on these mechanisms, safety and immunogenicity issues and various adverse events of the recombinant enzymes used for therapy are discussed. Section 4, provides discussion on the prospective and future developments of new therapeutic enzymes. This book is aimed at academics, researchers and students undertaking advanced undergraduate/postgraduate programs in the biopharmaceutical/biotechnology area who wish to gain a comprehensive understanding of enzyme-based therapeutic molecules.

The ESC Textbook of Intensive and Acute Cardiovascular Care

The ESC Textbook of Intensive and Acute Cardiovascular Care PDF Author: Marco Tubaro
Publisher: Oxford University Press
ISBN: 0192589199
Category : Medical
Languages : en
Pages : 800

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Book Description
The ESC Textbook of Intensive and Acute Cardiovascular Care is the official textbook of the Acute Cardiovascular Care Association (ACVC) of the ESC. Cardiovascular diseases (CVDs) are a major cause of premature death worldwide and a cause of loss of disability-adjusted life years. For most types of CVD early diagnosis and intervention are independent drivers of patient outcome. Clinicians must be properly trained and centres appropriately equipped in order to deal with these critically ill cardiac patients. This new updated edition of the textbook continues to comprehensively approach all the different issues relating to intensive and acute cardiovascular care and addresses all those involved in intensive and acute cardiac care, not only cardiologists but also critical care specialists, emergency physicians and healthcare professionals. The chapters cover the various acute cardiovascular diseases that need high quality intensive treatment as well as organisational issues, cooperation among professionals, and interaction with other specialities in medicine. SECTION 1 focusses on the definition, structure, organisation and function of ICCU's, ethical issues and quality of care. SECTION 2 addresses the pre-hospital and immediate in-hospital (ED) emergency cardiac care. SECTIONS 3-5 discuss patient monitoring, diagnosis and specific procedures. Acute coronary syndromes (ACS), acute decompensated heart failure (ADHF), and serious arrhythmias form SECTIONS 6-8. The main other cardiovascular acute conditions are grouped in SECTION 9. Finally SECTION 10 is dedicated to the many concomitant acute non-cardiovascular conditions that contribute to the patients' case mix in ICCU. This edition includes new chapters such as low cardiac output states and cardiogenic shock, and pacemaker and ICDs: troubleshooting and chapters have been extensively revised. Purchasers of the print edition will also receive an access code to access the online version of the textbook which includes additional figures, tables, and videos to better to better illustrate diagnostic and therapeutic techniques and procedures in IACC. The third edition of the ESC Textbook of Intensive and Acute Cardiovascular Care will establish a common basis of knowledge and a uniform and improved quality of care across the field.

New Therapeutic Agents in Thrombosis and Thrombolysis, Third Edition

New Therapeutic Agents in Thrombosis and Thrombolysis, Third Edition PDF Author: Jane E. Freedman
Publisher: CRC Press
ISBN:
Category : Medical
Languages : en
Pages : 718

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Book Description
An essential text for cardiologists, hematologists, and pharmacologists, this third edition is a resource on current agent development technology for treating cardiovascular and thromboembolic diseases. It covers advances in scientific discovery, the growing number of patients and indications for antithrombotics, and more.

Fibrinolytics and Antifibrinolytics

Fibrinolytics and Antifibrinolytics PDF Author: Fritz Markwardt
Publisher: Springer Science & Business Media
ISBN: 3642668631
Category : Medical
Languages : en
Pages : 663

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Book Description
Disturbances of haemostasis and thromboembolic disorders still constitute a great problem in clinical practice. Increasing insight into the mechanism of blood coagula tion has led to more effective therapy and prophylaxis. Particularly, the understand ing of the biochemistry of fibrinolysis has provided possibilities for the pharma cological interference of these processes, which has resulted in effective haemostatic agents and useful antithrombotic ones. The development of antifibrinolytics for interfering with pathological fibrinolytic processes is nearly complete and has led to the development of drugs essential to the therapy of hyperfibrinolytic bleeding. The search for fibrinolytics for dissolving intravascular thrombi has led to highly effective compounds. This development is still under way and promising results are hoped. Spontaneous dissolution of blood clots is a phenomenon which was described a century ago. First investigations of this process assured that there is in the organism a system capable of removing the fibrin which is formed during blood coagulation after it has fulfilled its physiological function. This fibrinolytic system is specifically adapted to the degradation of insoluble fibrin into soluble degradation products. In the past 30 years, thorough investigation of this system has clarified the fibrinolytic process, its physiological role and its meaning as a pathogenetic principle. A good knowledge of these processes is required for an understanding of the effects and side effects of fibrinolytics and antifibrinolytics, which comprise the basis of methods for the detection of fibrinolytic processes in the organism and of the control of therapy with these drugs.

Anesthetic Pharmacology

Anesthetic Pharmacology PDF Author: Alex S. Evers
Publisher: Cambridge University Press
ISBN: 1139497022
Category : Medical
Languages : en
Pages : 2902

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Book Description
In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Medical Pharmacology and Therapeutics E-Book

Medical Pharmacology and Therapeutics E-Book PDF Author: Derek G. Waller
Publisher: Elsevier Health Sciences
ISBN: 0702055034
Category : Medical
Languages : en
Pages : 741

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Book Description
This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice