Synthesis Green Metrics

Synthesis Green Metrics PDF Author: John Andraos
Publisher: CRC Press
ISBN: 0429683421
Category : Science
Languages : en
Pages : 486

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Book Description
Green chemistry promotes improved syntheses as an intellectual endeavour that can have a great impact both on preserving and utilizing our planet’s finite resources and the quality of human life. This masterful accomplishment provides an evaluation of environmental impact metrics according to life cycle assessment analysis based on the Mackay compartment environmental model and Guinée environmental impact potentials formalism. Assumptions, limitations, and dealing with missing data are addressed. Best literature resources for finding key toxicological parameters are provided and applied to individual reactions as well as entire synthesis plans, in order to target molecules of interest. Key Features: Provides an evaluation of environmental impact metrics according to life cycle assessment analysis Summarises safety-hazard metrics according to the same model as life cycle assessment including occupational exposure limits, risk phrases, flammability, and other physical parameters The book will be useful in a range of chemistry courses, from undergraduate to advanced graduate courses, whether based in lectures, tutorials or laboratory experiments

Green Chemistry Metrics

Green Chemistry Metrics PDF Author: Andrew P. Dicks
Publisher: Springer
ISBN: 3319105000
Category : Science
Languages : en
Pages : 95

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Book Description
This contribution to SpringerBriefs in Green Chemistry outlines and discusses the four major green chemistry metrics (atom economy, reaction mass efficiency, E factor and process mass intensity), at a level that is comprehensible by upper-level undergraduates. Such students have previously received fundamental training in organic chemistry basics, and are ideally positioned to learn about green chemistry principles, of which metrics is one foundational pillar. Following this, other green metrics in common use are discussed, along with applications that allow important calculations to be easily undertaken. Finally, an introduction to metrics in the context of life cycle analyses is presented. It should be noted that no other available publication teaches green chemistry metrics in detail with an emphasis on educating undergraduates, whilst simultaneously providing a contemporary industrial flavour to the material.

Reaction Green Metrics

Reaction Green Metrics PDF Author: John Andraos
Publisher: CRC Press
ISBN: 0429754426
Category : Science
Languages : en
Pages : 592

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Book Description
This book contains a series of exercises and problems posed in the subject of green metrics. Essentially it is a "how to" book on evaluating the material efficiency, environmental impact, safety-hazard impact, and energy efficiency of any kind of chemical reaction or synthesis plan. Only the essential green metrics in each of these categories are used. The introduction highlights the hierarchy of metrics used throughout the book, explains the structure of how the book is arranged, how the problems are posed, and how the reader is to use the book. Examples refer to themes according to the headings given in the table of contents and are arranged in a hierarchical order. Key Features: The topics cover fundamentals in chemistry and the chemical industry in a blended fashion A unique text covering the fundamentals of green metrics from materials efficiency and environmental and safety-hazard impact, to new green technologies and more The book will be useful in a range of chemistry courses, from early undergraduate to advanced graduate courses, whether based in lectures, tutorials or laboratory experiments Using an extensive glossary of terms used in green metrics, each chapter has a specified theme where the relevant metrics definitions pertaining to that theme will be given with one or two illustrative worked examples Supplemental web-based downloadable material including extra problems, full solutions, Excel files, ChemDraw files, templates, and exercises

Synthesis Green Metrics

Synthesis Green Metrics PDF Author: John Andraos
Publisher: CRC Press
ISBN: 042968343X
Category : Science
Languages : en
Pages : 514

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Book Description
Green chemistry promotes improved syntheses as an intellectual endeavour that can have a great impact both on preserving and utilizing our planet’s finite resources and the quality of human life. This masterful accomplishment provides an evaluation of environmental impact metrics according to life cycle assessment analysis based on the Mackay compartment environmental model and Guinée environmental impact potentials formalism. Assumptions, limitations, and dealing with missing data are addressed. Best literature resources for finding key toxicological parameters are provided and applied to individual reactions as well as entire synthesis plans, in order to target molecules of interest. Key Features: Provides an evaluation of environmental impact metrics according to life cycle assessment analysis Summarises safety-hazard metrics according to the same model as life cycle assessment including occupational exposure limits, risk phrases, flammability, and other physical parameters The book will be useful in a range of chemistry courses, from undergraduate to advanced graduate courses, whether based in lectures, tutorials or laboratory experiments

The Algebra of Organic Synthesis

The Algebra of Organic Synthesis PDF Author: John Andraos
Publisher: CRC Press
ISBN: 1420093290
Category : Science
Languages : en
Pages : 1221

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Book Description
The Algebra of Organic Synthesis combines the aims, philosophies, and efforts involved in organic synthesis, reaction optimization, and green chemistry with techniques for determining quantitatively just how "green" synthesis plans are. It provides the first complete quantitative description of synthesis strategy analysis in the context of green ch

Eco-friendly Synthesis of Fine Chemicals

Eco-friendly Synthesis of Fine Chemicals PDF Author: Roberto Ballini
Publisher: Royal Society of Chemistry
ISBN: 1847559085
Category : Science
Languages : en
Pages : 313

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Book Description
During these early years, the chronic toxicological properties of chemicals were often completely unknown and many unwittingly became indispensable tools of the trade. Early pioneers in green chemistry included Trost (who developed the atom economy principle) and Sheldon (who developed the E-Factor). These measures were introduced to encourage the use of more sustainable chemistry and provide some benchmarking data to encourage scientists to aspire to more benign synthesis. Green chemistry is essentially the design of chemical processes and procedures that reduce or eliminate the use, or the generation, of hazardous substances. Green chemistry is a growing area of research and an increasing number of researchers are now involved in this field. The number of publications has dramatically increased and new recognition of advances made is necessary with respect to other research areas.

Introduction to Green Chemistry

Introduction to Green Chemistry PDF Author: Albert Matlack
Publisher: CRC Press
ISBN: 1439882118
Category : Science
Languages : en
Pages : 602

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Book Description
The book covers traditional green chemistry topics, including catalysis, benign solvents, and alternative feedstocks. It also discusses relevant but less frequently covered topics with chapters such as Chemistry of Longer Wear and Population and the Environment. This coverage highlights the importance of chemistry to everyday life and demonstrates the benefits the expanded exploitation of green chemistry can have for society. Copiously illustrated with over 800 figures, this second edition provides an update from the frontiers of the field.

Green Metrics

Green Metrics PDF Author:
Publisher: John Wiley & Sons
ISBN: 3527695265
Category : Science
Languages : en
Pages : 400

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Book Description
Volume 11 of the Handbook of Green Chemistry series identifies, explains and expands on green chemistry and engineering metrics, describing how the two work together, backed by numerous practical applications. Up-to-date and authoritative, this ready reference covers the development and application of sustainable chemistry along with engineering metrics in both academia and industry, providing the latest information on fundamental aspects of metrics, practical realizations and example case studies. Additionally, it outlines how metrics have been used to facilitate developments in sustainable and green chemistry. The different concepts of and approaches to metrics are applied to fundamental problems in chemistry and the focus is firmly placed on their use to promote the development and implementation of more sustainable and green chemistry and technology in the production of chemicals and related products. Starting with molecular design, followed by chemical route evaluation, chemical process metrics and product assessment, by the end readers will have a complete set of metrics to choose from as they move a chemical conception to final product. Of high interest to academics and chemists working in industry.

Green Syntheses

Green Syntheses PDF Author: Pietro Tundo
Publisher: CRC Press
ISBN: 1466513209
Category : Science
Languages : en
Pages : 250

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Book Description
Many new methods directed to organic and inorganic syntheses of useful intermediates are being developed to specifically address green and sustainable chemistry principles. Highlighting the importance of green metrics, the Green Syntheses series focuses on how to reliably substantiate and validate the level of "greenness" of chemical processes, providing practical synthetic methodologies and metrics for a rigorous proof of "greenness." In Green Syntheses, Volume 1, the first book of its kind, the editors determine appropriate material efficiency green metrics and use them to compare syntheses provided by the chapter authors with those previously published. Presenting a new concept in green chemistry, this book demonstrates what future publications might look like if green principles are followed and also incorporate the important ethical aspect of supplying rigorous procedures in laboratory practice and evidence of greenness of a given synthesis protocol using metrics analysis. This inaugural volume initiates the much-needed transition from stating the 12 guiding principles on the philosophy of green chemistry to the actualization and verification of it. The book addresses primarily the issue of material efficiency metrics, which measure the amount of waste produced relative to desired product. In each contributed example, full experimental details are given showing all quantities of materials used in the procedure. Authors discuss the green merits of their protocols in conjunction with the results of a thorough metrics analysis, allowing for in-depth discussion of insights about synthesis strategy and performance characteristics of the new and prior cited plans.

Green Techniques for Organic Synthesis and Medicinal Chemistry

Green Techniques for Organic Synthesis and Medicinal Chemistry PDF Author: Wei Zhang
Publisher: John Wiley & Sons
ISBN: 1119288584
Category : Science
Languages : en
Pages : 728

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Book Description
An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.