Author: Daniel P. Lisbon
Publisher:
ISBN:
Category :
Languages : en
Pages : 270
Book Description
Synthesis and Characterization of Transition Metal Complexes Containing Oxazoline and Pyrazole Ligands
Author: Daniel P. Lisbon
Publisher:
ISBN:
Category :
Languages : en
Pages : 270
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 270
Book Description
Synthesis, Characterization, and Reactivity of Transition Metal Complexes Containing Multi-donor Ligands
Author: John C. Linehan
Publisher:
ISBN:
Category :
Languages : en
Pages : 514
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 514
Book Description
Synthesis, Reactivity and Structural Characterization of Transition Metal Complexes Containing Dibenzotetraaza [14] Annulene Macrocyclic Ligands
Author: Marvin Cecil Weiss
Publisher:
ISBN:
Category : Transition metal compounds
Languages : en
Pages : 924
Book Description
Publisher:
ISBN:
Category : Transition metal compounds
Languages : en
Pages : 924
Book Description
Synthesis and characterization of transition and some Group 14 metal complexes containing ligands derived from 2- acetylpyridine and hydrazide derivatives, and their antiplasmodium activities
Author: Philipus Nghilukunaye Hishimone
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 102
Book Description
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 102
Book Description
The Synthesis and Characterization of Some Transition Metal Complexes Derived from Oxime Ligands
Author: Gary A. Nicholson
Publisher:
ISBN:
Category :
Languages : en
Pages : 362
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 362
Book Description
Synthesis and Characterization of Helical Ligand Transition Metal Complexes
Author: Andrew Fessak
Publisher:
ISBN:
Category :
Languages : en
Pages : 197
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 197
Book Description
Synthesis and Structural Characterization of Mono- and Dinuclear Transition Metal Complexes Containing the Tetraaza-[14] Annulene Ligand
Author: Joanna Czuchajowska-Wiesinger
Publisher:
ISBN:
Category : Transition metal complexes
Languages : en
Pages : 362
Book Description
Publisher:
ISBN:
Category : Transition metal complexes
Languages : en
Pages : 362
Book Description
Synthesis and Characterization of Transition Metal Complexes of the Ligand DDDT−2, 5,6-Dihydro-l,4-dithiin-2,3-dithiolate
Author: Jane Alena Hanna Welch
Publisher:
ISBN:
Category :
Languages : en
Pages : 570
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 570
Book Description
Rational Design, Synthesis and Characterization of Amide Functionalized Pyridine and Benzimidazole Transition Metal Complexes
Author: Samuel S. K. Asem
Publisher:
ISBN:
Category : Benzimidazoles
Languages : en
Pages : 576
Book Description
This study expands our efforts to make a new class of Pt (II) compounds analogous to cisplatin and its derivatives using sterically hindered ligands. Pt compounds in this series have been synthesized using specially designed pyridine and benzimidazole ligands. These heterocycles, amide functionalized at position 2 with aryl and alkyl pendants, rapidly change their mode of coordination depending on the pH of the medium. These ligands, synthesized using condensation chemistry, also coordinate to Co(II), Ni(H), Cu(lI), and Zn(1I) generally as anionic bis-chelates through the benzimidazole nitrogen and the carbonyl oxygen, creating a four-coordinate complex with the exception of an unusual trigonal bipyramidal Zn(H) complex. I H NMR temperature studies reveal that these ligands interconvert between imide and amide isomers and that electron withdrawing pendants favor amide isomers. Crystal structures of Co(II) and Ni(1I) complexes of N-( I-methylbenzimidazol-2-yl)cyclohexanecarboxamide, for example, show two ligands bind per metal ion when reacted with acetate and nitrate salts. The bischelates of these Ni(1I) complexes also show expansions of their coordination spheres from four to five-coordinate. Furthermore, these Ni(II) bis-chelated complexes possess square planar or distorted 4-coordinate geometries. The synthesis and properties of several new Pt (II) complexes containing these ligands will be presented. A second generation and novel complex class containing metal-binding, linker and recognition domains is reported. Both classes of Pt complexes were obtained using a synthetic methodology which favors the cis isomers. The second generation complex crystallizes in the monoclinic space group P2dn with lattice dimensions a = 17.7393(5) A, b = 11.4632(3) A, c = 19.3959(5) A and ~ = 99.794(3)°. These complexes have been characterized using physical methods that include X-ray crystallography, IH &13C NMR, Mass spectrometry, UV and IR spectroscopies. Complexes similar in structure to cisplatin and carboplatin show varying cytotoxic properties toward different cancer cell lines. Additionally, some of these new Pt complexes show comparable and promising cytotoxicity against prostate cancer cell lines.
Publisher:
ISBN:
Category : Benzimidazoles
Languages : en
Pages : 576
Book Description
This study expands our efforts to make a new class of Pt (II) compounds analogous to cisplatin and its derivatives using sterically hindered ligands. Pt compounds in this series have been synthesized using specially designed pyridine and benzimidazole ligands. These heterocycles, amide functionalized at position 2 with aryl and alkyl pendants, rapidly change their mode of coordination depending on the pH of the medium. These ligands, synthesized using condensation chemistry, also coordinate to Co(II), Ni(H), Cu(lI), and Zn(1I) generally as anionic bis-chelates through the benzimidazole nitrogen and the carbonyl oxygen, creating a four-coordinate complex with the exception of an unusual trigonal bipyramidal Zn(H) complex. I H NMR temperature studies reveal that these ligands interconvert between imide and amide isomers and that electron withdrawing pendants favor amide isomers. Crystal structures of Co(II) and Ni(1I) complexes of N-( I-methylbenzimidazol-2-yl)cyclohexanecarboxamide, for example, show two ligands bind per metal ion when reacted with acetate and nitrate salts. The bischelates of these Ni(1I) complexes also show expansions of their coordination spheres from four to five-coordinate. Furthermore, these Ni(II) bis-chelated complexes possess square planar or distorted 4-coordinate geometries. The synthesis and properties of several new Pt (II) complexes containing these ligands will be presented. A second generation and novel complex class containing metal-binding, linker and recognition domains is reported. Both classes of Pt complexes were obtained using a synthetic methodology which favors the cis isomers. The second generation complex crystallizes in the monoclinic space group P2dn with lattice dimensions a = 17.7393(5) A, b = 11.4632(3) A, c = 19.3959(5) A and ~ = 99.794(3)°. These complexes have been characterized using physical methods that include X-ray crystallography, IH &13C NMR, Mass spectrometry, UV and IR spectroscopies. Complexes similar in structure to cisplatin and carboplatin show varying cytotoxic properties toward different cancer cell lines. Additionally, some of these new Pt complexes show comparable and promising cytotoxicity against prostate cancer cell lines.
Transition Metals in the Synthesis of Complex Organic Molecules
Author: Louis S. Hegedus
Publisher: University Science Books
ISBN: 9781891389047
Category : Science
Languages : en
Pages : 358
Book Description
This second edition offers easy access to the field of organotransition metal chemistry. The book covers the basics of transition metal chemistry, giving a practical introduction to organotransition reaction mechanisms.
Publisher: University Science Books
ISBN: 9781891389047
Category : Science
Languages : en
Pages : 358
Book Description
This second edition offers easy access to the field of organotransition metal chemistry. The book covers the basics of transition metal chemistry, giving a practical introduction to organotransition reaction mechanisms.