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Author: Moses Allen Starr
Publisher:
ISBN:
Category : Nervous system
Languages : en
Pages : 206
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Book Description
2000, Gift of the South Carolina State Hospital.
Author: Moses Allen Starr
Publisher:
ISBN:
Category : Nervous system
Languages : en
Pages : 206
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Book Description
2000, Gift of the South Carolina State Hospital.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309292492
Category : Medical
Languages : en
Pages : 107
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Book Description
Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.
Author: Jean Martin Charcot
Publisher: BoD – Books on Demand
ISBN: 338502403X
Category : Fiction
Languages : en
Pages : 338
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Book Description
Reprint of the original, first published in 1877.
Author: M. Allen Starr
Publisher:
ISBN: 9781331140627
Category : Medical
Languages : en
Pages : 200
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Book Description
Excerpt from Synopsis of Lectures Upon Diseases of the Nervous System: Delivered at the College of Physicians and Surgeons, Medical Department of Columbia University, New York Examples. The nervous system of a frog experimentally deprived of its hemispheres, capable of automatic acts of swimming. The automatic act of respiration in man. In man the facial, laryngeal, intercostal, thoracic, and diaphragmatic respiratory muscles act in definite succession and rhythm in the act of breathing; and this act is presided over by a single centre in the medulla controlling the lower medullary and spinal centres. The highest type of nervous system is the complex type. There are the lower centres as in the simple type. There are higher centres controlling the lower centres, as in the compound type. There is a supreme mass controlling both the others. This is the form found in all vertebrates, and the degree of evolution in the highest or supreme mass determines the place of the animal in the scale of intelligence. In man the supreme mass is the cerebral cortex, the next lower or automatic centres are the optic thalami and basal ganglia, including gray masses in the cerebral axis; the lowest or reflex centres are the cranial nerve nuclei in the cerebral axis and the gray matter of the spinal cord segments. These distant gray masses are joined with one another in all possible combinations by means of the white nerve tracts, which pass in all directions around and within them. The human nervous system consists of a peripheral system and a central system. The peripheral system comprises all the nerves. The central system includes: First. The spinal cord and cranial nerve nuclei. Secondly. The cerebellum; gray masses of the medulla, pons, and crura cerebri; corpora quadrigemina, optic thalami, and corpora striata. Thirdly. The cerebral cortex. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 706
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Author: Jean Martin Charcot
Publisher:
ISBN:
Category :
Languages : en
Pages : 470
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Book Description
Author: J-M. Charcot
Publisher: Routledge
ISBN: 131791001X
Category : Psychology
Languages : en
Pages : 527
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Book Description
Originally published in 1991 as part of the Tavistock Classics in the History of Psychiatry series, this re-edition of J-M. Charcot’s Clinical Lectures on Diseases of the Nervous System provides a unique opportunity to examine the work of one of the last century’s most controversial and admired physicians. Widely esteemed for his work in neuropathology, Charcot was also an innovator in the study of hysteria, making important contributions to its study in both women and men. The Clinical Lectures reproduced here are especially important for two key reasons. First, they provide insight into Charcot’s often neglected study of male hysteria, especially traumatic shock, as well as, hysteria among children. Secondly, they give an opportunity to examine his clinical method and style. His presentations and scholarly compilations greatly influenced an entire generation of French and other physicians interested in the study of the ‘unconscious’ during the turn of the century. The introduction, which precedes the work, places the volume in its social, political and historical context. It highlights the key features of the historiographical debate surrounding Charcot, which ranges in scope from the social and intellectual history of the Third Republic through that of early psychoanalysis. It then proceeds with an examination of the key themes – both substantive and methodological – underlying Charcot’s researches, providing both a general entrée into the history of medicine and society in this period, as well as an explication du texte which carefully analyses the lectures themselves.
Author: Jean Martin Charcot
Publisher:
ISBN:
Category : Nervous system
Languages : en
Pages : 468
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Author: Moses Allen Starr
Publisher:
ISBN:
Category : Nervous system
Languages : en
Pages : 87
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Book Description
Author:
Publisher:
ISBN:
Category : American literature
Languages : en
Pages : 2162
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Book Description
