Author:
Publisher: Elsevier
ISBN: 0080456111
Category : Science
Languages : en
Pages : 342
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Book Description
Surface activity is present in living systems; for example in body fluid or cell soup and molecules of surface-active nature are crucial to living matter and its organization. Surface Activity in Drug Action proposes "a liquid membrane hypothesis of drug action" for surface-active drugs. Chapters 1-7 contains an account of the hypothesis and chapter 8 contains a general account of the application of surface activity in therapeutics. The methodology and presentation of the information makes Surface Activity in Drug Action valuable reading for students and researchers interested in surface activity.* Is clearly written * Includes contributions from prominent names in the field, such as Bhise and Subrahmanyam* Contains a general account of the application of surface activity in therapeutics
Author: Li Di
Publisher: Elsevier
ISBN: 0080557619
Category : Science
Languages : en
Pages : 549
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Book Description
Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. - Serves as an essential working handbook aimed at scientists and students in medicinal chemistry - Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies - Discusses improvements in pharmacokinetics from a practical chemist's standpoint
Author: Louis Sanford Goodman
Publisher: McGraw Hill Professional
ISBN: 0071443436
Category : Medical
Languages : en
Pages : 1232
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Book Description
Put the authority of Goodman & Gilman's in the palm of your hand! 5 STAR DOODY'S REVIEW! "...the most authoritative and trusted source of pharmacological information, has now spawned a portable pocket drug guide....This manual extracts the essential core drug information from the eleventh edition of the parent book, referring the reader to the online version of the parent book for historical aspects, many chemical and clinical details, and additional figures and references. This makes G & G a very useful book. This will be of use to individuals in training or practice in the fields of pharmacy, medicine, nursing, or allied health disciplines where knowledge of drug actions are important....Each chapter provides the core essential information provided in the parent book in a very readable format. Readers can use this easy to handle and read manual for essential information along with the online version of the parent book as a reference for more in-depth specific information on drugs."--Doody's Review Service The Goodman & Gilman Manual of Pharmacology and Therapeutics offers the renowned content of Goodman & Gilman's Pharmacological Basis of Therapeutics, Eleventh Edition, condensed into an ultra-handy, streamlined reference. More than just a pocket drug guide, this indispensable resource offers: A carry-along source of essential fundamental information, with all the authority of Goodman & Gilman's Pharmacological Basis of Therapeutics, Eleventh Edition The benefits of the world's leading pharmacology text in a convenient, portable format Comprehensive, yet streamlined and clinically relevant coverage of the pharmacological basis of therapeutics High-yield overview of pharmacokinetics, pharmacodynamics, and the foundations of pharmacology Expert insights into the properties, mechanisms, and uses of all the major drug classes Considerations of vital patient-specific issues
Author: Jennifer B. Dressman
Publisher: CRC Press
ISBN: 1420077341
Category : Medical
Languages : en
Pages : 432
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Book Description
Oral Drug Absorption, Second Edition thoroughly examines the special equipment and methods used to test whether drugs are released adequately when administered orally. The contributors discuss methods for accurately establishing and validating in vitro/in vivo correlations for both MR and IR formulations, as well as alternative approaches for MR an
Author: Alex S. Evers
Publisher: Cambridge University Press
ISBN: 1139497022
Category : Medical
Languages : en
Pages : 2902
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Book Description
In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.
Author: Ashutosh Kar
Publisher: New Age International
ISBN: 9788122415650
Category : Pharmacology
Languages : en
Pages : 832
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Book Description
The Qualified Success And General Appeal Of Medicinal Chemistry Is Not Only Confined To The Indian Subcontinent, But It Has Also Won An Overwhelming Popularity In Other Parts Of The World. Specific Care Has Been Taken To Maintain And Sustain The Fundamental Philosophy Of The Textbook Embracing Rigidly The Original Pattern And Style Of Presentation With A Particular Expatiated Treatment Of Synthesis Of Potential Medicinal Compounds For The Ultimate Benefits Of The Teachers And The Taught Alike.The Present Thoroughly Revised And Skilfully Expanded Fourth Edition Essentially Contains Three New And Important Chapters, Namely : Molecular Modeling And Drug Design (Chapter 3), Adrenocortical Steroids (Chapter 24), And Antimycobacterial Agents (Chapter 26) So As To Make The Textbook More Useful To Its Readers.With The Advent Of Thirty Chapters The Present Updated Form Of Medicinal Chemistry Will Prove To Be An Asset For M. Pharm./B. Pharm. Degree Students, M. Sc. Pharmaceutical Chemistry, M.Sc. Applied Chemistry And M. Sc. Industrial Chemistry Throughout The Indian Universities.Medicinal Chemistry Appears As A Newly Designed And Artistically Presented In A Two-Colour Scheme So As To Facilitate A Distinctly More Effective Use Of The Book.This Highly Readable, Lucid, Handy, And Exceptionally Knowledgeable Textbook Will Definitely Win A Better, Bigger, And Confident Place For Itself Amongst Its Valued Readers.
Author: Gerard Marshall Raj
Publisher: Springer Nature
ISBN: 9813297794
Category : Medical
Languages : en
Pages : 410
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Book Description
This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.
Author: Mitchell J. Stoklosa
Publisher:
ISBN: 9780812110074
Category : Medical
Languages : en
Pages : 428
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Book Description
Author:
Publisher:
ISBN:
Category : American periodicals
Languages : en
Pages : 856
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Book Description
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309175771
Category : Medical
Languages : en
Pages : 276
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Book Description
The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.
