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Author: Guido Bocci
Publisher: Springer
ISBN: 3662436043
Category : Medical
Languages : en
Pages : 302
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Book Description
This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.
Author: Guido Bocci
Publisher: Springer
ISBN: 3662436043
Category : Medical
Languages : en
Pages : 302
Get Book Here
Book Description
This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.
Author: Yoshitsugu Oono
Publisher: Springer Science & Business Media
ISBN: 4431540296
Category : Science
Languages : en
Pages : 307
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Book Description
The most important characteristic of the “world filled with nonlinearity” is the existence of scale interference: disparate space–time scales interfere with each other. Thus, the effects of unknowable scales invade the world that we can observe directly. This leads to various peculiar phenomena such as chaos, critical phenomena, and complex biological phenomena, among others. Conceptual analysis and phenomenology are the keys to describe and understand phenomena that are subject to scale interference, because precise description of unfamiliar phenomena requires precise concepts and their phenomenological description. The book starts with an illustration of conceptual analysis in terms of chaos and randomness, and goes on to explain renormalization group philosophy as an approach to phenomenology. Then, abduction is outlined as a way to express what we have understood about the world. The book concludes with discussions on how we can approach genuinely complex phenomena, including biological phenomena. The main target of this volume is young people who have just started to appreciate the world seriously. The author also wishes the book to be helpful to those who have been observing the world, but who wish to appreciate it afresh from a different angle.
Author: Tsuneyoshi Nakayama
Publisher:
ISBN: 9783662051948
Category :
Languages : en
Pages : 224
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Book Description
Author: Walther Kaufmann
Publisher:
ISBN:
Category :
Languages : en
Pages : 432
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Book Description
Author: Jearl Walker
Publisher: John Wiley & Sons
ISBN: 9788126517824
Category :
Languages : en
Pages : 316
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Book Description
This new version now contains answers to all the over 600 stimulating questions. Walker covers the entirety of naked-eye physics by exploring problems of the everyday world. He focuses on the flight of Frisbees, sounds of thunder, rainbows, sand dunes, soap bubbles, etc., and uses such familiar objects as rubber bands, eggs, tea pots, and Coke bottles. Many references to outside sources guide the way through the problems. Now the inclusion of answers provides immediate feedback, making this an extraordinary approach in applying all of physics to problems of the real world.· Hiding Under the Covers, Listening for the Monsters· The Walrus Speaks of Classical Mechanics· Heat Fantasies and Other Cheap Thrills of the Night· The Madness of Stirring Tea· She Comes in Colors Everywhere· The Electrician's Evil and the Ring's Magic· The Walrus Has His Last Say and Leaves Us Assorted Goodies
Author: Fedor Bogomolov
Publisher: Springer Science & Business Media
ISBN: 0817649344
Category : Mathematics
Languages : en
Pages : 316
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Book Description
Rationality problems link algebra to geometry, and the difficulties involved depend on the transcendence degree of $K$ over $k$, or geometrically, on the dimension of the variety. A major success in 19th century algebraic geometry was a complete solution of the rationality problem in dimensions one and two over algebraically closed ground fields of characteristic zero. Such advances has led to many interdisciplinary applications to algebraic geometry. This comprehensive book consists of surveys of research papers by leading specialists in the field and gives indications for future research in rationality problems. Topics discussed include the rationality of quotient spaces, cohomological invariants of quasi-simple Lie type groups, rationality of the moduli space of curves, and rational points on algebraic varieties. This volume is intended for researchers, mathematicians, and graduate students interested in algebraic geometry, and specifically in rationality problems. Contributors: F. Bogomolov; T. Petrov; Y. Tschinkel; Ch. Böhning; G. Catanese; I. Cheltsov; J. Park; N. Hoffmann; S. J. Hu; M. C. Kang; L. Katzarkov; Y. Prokhorov; A. Pukhlikov
Author: Frank M. White
Publisher:
ISBN: 9780071009959
Category : Viscous flow
Languages : en
Pages : 614
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Book Description
Designed for higher level courses in viscous fluid flow, this text presents a comprehensive treatment of the subject. This revision retains the approach and organization for which the first edition has been highly regarded, while bringing the material completely up-to-date. It contains new information on the latest technological advances and includes many more applications, thoroughly updated problems and exercises.
Author: Ichirō Tamura
Publisher: American Mathematical Soc.
ISBN: 9780821842003
Category : Mathematics
Languages : en
Pages : 212
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Book Description
This book provides historical background and a complete overview of the qualitative theory of foliations and differential dynamical systems. Senior mathematics majors and graduate students with background in multivariate calculus, algebraic and differential topology, differential geometry, and linear algebra will find this book an accessible introduction. Upon finishing the book, readers will be prepared to take up research in this area. Readers will appreciate the book for its highly visual presentation of examples in low dimensions. The author focuses particularly on foliations with compact leaves, covering all the important basic results. Specific topics covered include: dynamical systems on the torus and the three-sphere, local and global stability theorems for foliations, the existence of compact leaves on three-spheres, and foliated cobordisms on three-spheres. Also included is a short introduction to the theory of differentiable manifolds.
Author: Richard G. Budynas
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 968
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Book Description
This book provides a broad and comprehensive coverage of the theoretical, experimental, and numerical techniques employed in the field of stress analysis. Designed to provide a clear transition from the topics of elementary to advanced mechanics of materials. Its broad range of coverage allows instructors to easily select many different topics for use in one or more courses. The highly readable writing style and mathematical clarity of the first edition are continued in this edition. Major revisions in this edition include: an expanded coverage of three-dimensional stress/strain transformations; additional topics from the theory of elasticity; examples and problems which test the mastery of the prerequisite elementary topics; clarified and additional topics from advanced mechanics of materials; new sections on fracture mechanics and structural stability; a completely rewritten chapter on the finite element method; a new chapter on finite element modeling techniques employed in practice when using commercial FEM software; and a significant increase in the number of end of chapter exercise problems some of which are oriented towards computer applications.
Author: Usha Goswami
Publisher: Psychology Press
ISBN: 9780863778247
Category : Medical
Languages : en
Pages : 356
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Book Description
This textbook aims to provide a selective, but representative, review of work in cognitive development, grouped around themes that are familiar from textbooks of adult cognition. The book focuses on the question of what develops, rather than on why it develops. The findings of a given experimental study what develops are generally fixed, but the interpretation of what particular findings mean why is fluid. Some of the experiments discussed in this book have alternative explanations, and every student interested in children's cognition is invited to develop their own ideas about what different studies mean.
