Studies Directed Towards the Total Synthesis of Macrolide Antibiotics PDF Download
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Author: Charles Tweedt Buse
Publisher:
ISBN:
Category : Antibiotics
Languages : en
Pages : 320
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Book Description
Author: Charles Tweedt Buse
Publisher:
ISBN:
Category : Antibiotics
Languages : en
Pages : 320
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Book Description
Author: I. J. Burnside
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Author: Thaddeus R. Nieduzak
Publisher:
ISBN:
Category : Antibiotics
Languages : en
Pages : 202
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Author: Erick Moran Carreira
Publisher:
ISBN:
Category : Macrolide antibiotics
Languages : en
Pages : 352
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Author: Ian Stansfield
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Author: John Powell Daub
Publisher:
ISBN:
Category :
Languages : en
Pages : 440
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Author: Ravindar Kontham
Publisher: LAP Lambert Academic Publishing
ISBN: 9783848449583
Category :
Languages : en
Pages : 164
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Book Description
This monograph features the studies directed towards the total synthesis of architecturally and biologically interesting polypropionate natural products (-)-Ebelactone-A and (-)-Maurenone utilizing desymmetrization as a key strategy. ( )-Ebelactone A, show structural characteristics in common with macrolide antibiotics. Ebelactones act as potent inhibitors of esterase s, lipases and N-formylmethionine amino peptidases, and they have shown to produce enhance immune responses. They are also reported to inhibit cutinases produced by fungal pathogens. Novel biological activity combined with unique and challenging structure of Ebelactone, made this compound an exciting target for the total synthesis. Secondly, this book described an efficient synthetic protocol for polypropionate natural product (-)-Maurenone, which was isolated by Faulkner et al. in 1986 from specimens of the pulmonate mollusc Siphonaria maura. This monograph is unique in dealing with many interesting synthetic protocols including full experimental procedures, analytical data for all synthetic materials and complete reference sections. This monograph can be served as a good hand book for synthetic organic chemists.
Author: Eric L. Williams
Publisher:
ISBN:
Category : Organic compounds
Languages : en
Pages : 164
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Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 56
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Author: Benjamin Eric Blass
Publisher:
ISBN:
Category :
Languages : en
Pages : 490
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