Structure, Motion, Interaction and Expression of Biological Macromolecules PDF Download
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Author: Conversation in Biomolecular Stereodynamics 1997 State University of
Publisher:
ISBN: 9780940030763
Category : Science
Languages : en
Pages : 0
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Author: Conversation in Biomolecular Stereodynamics 1997 State University of
Publisher:
ISBN: 9780940030763
Category : Science
Languages : en
Pages : 0
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Book Description
Author: Ramaswamy H. Sarma
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 304
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Book Description
Author:
Publisher: Elsevier
ISBN: 0080496741
Category : Science
Languages : en
Pages : 583
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Book Description
RNA-Ligand Interactions, Part A focuses on structural biology methods. Major topics covered include semisynthetic methodologies (RNA synthetic methods and derivatization of RNA); RNA structure determination (X-ray crystallography, NMR, EM); techniques for monitoring RNA conformation and dynamics (solution methods and electrophoretic and spectroscopic methods); and modeling tertiary structure: Part B, its companion Volume 318 of Methods in Enzymology, focuses on molecular biology methods.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the Series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Author: E. Morton Bradbury
Publisher: Springer Science & Business Media
ISBN: 9401146314
Category : Medical
Languages : en
Pages : 311
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Book Description
Biomedical research will be revolutionised by the current efforts to sequence the human genome and the genomes of model organisms. Of the newly sequenced genes, 50% code for proteins of unknown functions, while as little as 5% of sequences in mammalian genomes code for proteins. New, genome-wide approaches are needed to draw together the knowledge that is emerging simultaneously in a number of fields of genome research. This volume is a high-level survey of the newly emerging concepts of structural biology and functional genomics for biologists, biochemists and medical researchers interested in genome research. Topics included are chromosome and chromatin organisation, novel DNA and RNA structures, DNA flexibility, supercoiling, prediction of protein functions, strategies for large scale structural analysis, and computer modelling.
Author: Prof. Jan Hermans
Publisher: John Wiley & Sons
ISBN: 1118733770
Category : Science
Languages : en
Pages : 411
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Book Description
Progressively builds a deep understanding of macromolecular behavior Based on each of the authors' roughly forty years of biophysics research and teaching experience, this text instills readers with a deep understanding of the biophysics of macromolecules. It sets a solid foundation in the basics by beginning with core physical concepts such as thermodynamics, quantum chemical models, molecular structure and interactions, and water and the hydrophobic effect. Next, the book examines statistical mechanics, protein-ligand binding, and conformational stability. Finally, the authors address kinetics and equilibria, exploring underlying theory, protein folding, and stochastic models. With its strong emphasis on molecular interactions, Equilibria and Kinetics of Biological Macromolecules offers new insights and perspectives on proteins and other macromolecules. The text features coverage of: Basic theory, applications, and new research findings Related topics in thermodynamics, quantum mechanics, statistical mechanics, and molecular simulations Principles and applications of molecular simulations in a dedicated chapter and interspersed throughout the text Macromolecular binding equilibria from the perspective of statistical mechanics Stochastic processes related to macromolecules Suggested readings at the end of each chapter include original research papers, reviews and monographs, enabling readers to explore individual topics in greater depth. At the end of the text, ten appendices offer refreshers on mathematical treatments, including probability, computational methods, Poisson equations, and defining molecular boundaries. With its classroom-tested pedagogical approach, Equilibria and Kinetics of Biological Macromolecules is recommended as a graduate-level textbook for biophysics courses and as a reference for researchers who want to strengthen their understanding of macromolecular behavior.
Author: Oleg Jardetzky
Publisher: IOS Press
ISBN: 9781586030322
Category : Biomolecules
Languages : en
Pages : 212
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Book Description
A collection of articles looking at modern structural biology, summarizing the applications of physical methods - such as x-ray diffraction, high resolution nuclear magnetic resonance and molecular dynamics - to the study of protein structure and dynamics. There is a review of contemporary thoughts within the field, looking at the mechanisms of alloateric transitions and allosteric control, the transmission of information within protein structures and the role of dynamics in determining the specificity of protein - ligand interactions. There is also a look at future innovations.
Author: Alessandra Carbone
Publisher: World Scientific
ISBN: 9814495182
Category : Science
Languages : en
Pages : 445
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Book Description
Half a billion years of evolution have turned the eye into an unbelievable pattern detector. Everything we perceive comes in delightful multicolored forms. Now, in the age of science, we want to comprehend what and why we see.Two dozen outstanding biologists, chemists, physicists, psychologists, computer scientists and mathematicians met at the Institut d'Hautes Etudes Scientifiques in Bures-sur-Yvette, France. They expounded their views on the physical, biological and physiological mechanisms creating the tapestry of patterns we see in molecules, plants, insects, seashells, and even the human brain. This volume comprises surveys of different aspects of pattern formation and recognition, and is aimed at the scientifically minded reader.
Author: C. Helene (ed)
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Oleg Jardetzky
Publisher: Springer Science & Business Media
ISBN: 1461558395
Category : Science
Languages : en
Pages : 308
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Book Description
From within complex structures of organisms and cells down to the molecular level, biological processes all involve movement. Muscular fibers slide on each other to activate the muscle, as polymerases do along nucleic acids for replicating and transcribing the genetic material. Cells move and organize themselves into organs by recognizing each other through macromolecular surface-specific interactions. These recognition processes involve the mu tual adaptation of structures that rely on their flexibility. All sorts of conformational changes occur in proteins involved in through-membrane signal transmission, showing another aspect of the flexibility of these macromolecules. The movement and flexibility are inscribed in the polymeric nature of essential biological macromolecules such as proteins and nucleic acids. For instance, the well-defined structures formed by the long protein chain are held together by weak noncovalent interac tions that design a complex potential well in which the protein floats, permanently fluctuating between several micro- or macroconformations in a wide range of frequencies and ampli tudes. The inherent mobility of biomolecular edifices may be crucial to the adaptation of their structures to particular functions. Progress in methods for investigating macromolecular structures and dynamics make this hypothesis not only attractive but more and more testable.
Author: Nadrian C. Seeman
Publisher: Cambridge University Press
ISBN: 1316431983
Category : Technology & Engineering
Languages : en
Pages : 269
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Book Description
Written by the founder of the field, this is the first text of its kind, providing a definitive introduction to structural DNA nanotechnology. Readers will learn everything there is to know about the subject from the unique perspective of the leading expert in the field. Topics covered range from origins and history, to design, experimental techniques, DNA nanomechanics devices, computing, and the uses of DNA nanotechnology in organising other materials. Clearly written, and benefiting from over 200 full colour illustrations, readers will find this an accessible and easy to follow text that is essential reading for anyone who wants to enter this rapidly growing field. Ideal for advanced undergraduate and graduate students, as well as researchers in a range of disciplines including nanotechnology, materials science, physics, biology, chemistry, computational science and engineering.
