Structure Elucidation and Progress Toward the Total Synthesis of (+)-Trienomycin A

Structure Elucidation and Progress Toward the Total Synthesis of (+)-Trienomycin A PDF Author: Weichyun Wong
Publisher:
ISBN:
Category :
Languages : en
Pages : 554

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Structure Elucidation and Progress Toward the Total Synthesis of (+)-Trienomycin A

Structure Elucidation and Progress Toward the Total Synthesis of (+)-Trienomycin A PDF Author: Weichyun Wong
Publisher:
ISBN:
Category :
Languages : en
Pages : 554

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Book Description


Dissertation Abstracts International

Dissertation Abstracts International PDF Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 912

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American Doctoral Dissertations

American Doctoral Dissertations PDF Author:
Publisher:
ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 704

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Targeting Oral Cancer

Targeting Oral Cancer PDF Author: Andrew Fribley
Publisher: Springer
ISBN: 3319276476
Category : Medical
Languages : en
Pages : 303

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Book Description
This book provides research-oriented care providers with up-to-date information on the oral cancer patient population, the ways in which we are treating them, and the scientific approaches being pursued in order to improve survival and reduce treatment-related morbidity. The text is organized into three sections covering epidemiology and management, cancer development and biomarkers, and breaking developments and novel approaches for drug discovery. The first section includes discussion of the emerging role of HPV in oral cancer and explains the surgical, chemotherapy and radiation approaches to treatment. Aspects such as molecular progression, the role of cancer stem cells in tumor development, and the value of various biomarkers are then examined. The final section is devoted to the latest advances and covers, among other topics, current clinical trials, emerging drug targets, and targeting of the unfolded protein response and of mediators of coagulation.

Van Nostrand's Encyclopedia of Chemistry

Van Nostrand's Encyclopedia of Chemistry PDF Author: Glenn D. Considine
Publisher: Wiley-Interscience
ISBN: 9780471615255
Category : Science
Languages : en
Pages : 1856

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Book Description
Scientists, engineers, and technologists in many fields need a knowledge of chemistry because of the importance of chemistry in diverse technologies. In addition, to "classical" topics of chemistry, the new Encyclopedia covers nanotechnology, fuel cell technology, green chemistry, forensic chemistry, supramolecular chemistry, combinatorial chemistry, materials chemistry, and proteomics. This fifth print edition has been revised and updated, and includes over 200 new articles, as well as 1,300 updated articles.

Practical Medicinal Chemistry with Macrocycles

Practical Medicinal Chemistry with Macrocycles PDF Author: Eric Marsault
Publisher: John Wiley & Sons
ISBN: 1119092566
Category : Science
Languages : en
Pages : 617

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Book Description
Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations

The Search for Bioactive Compounds from Microorganisms

The Search for Bioactive Compounds from Microorganisms PDF Author: Satoshi Omura
Publisher: Springer Science & Business Media
ISBN: 1461244129
Category : Science
Languages : en
Pages : 373

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Book Description
Biologically active compounds isolated from microorganisms continue to be vital to the development of new drugs and agricultural chemicals. This book was prepared by current and past members of the laboratory of Dr. Satoshi Omura of the Kitasato Institute in Japan. Dr. Omura and his colleagues have discovered and studied a number of important antibiotics, and in their work they have pioneered new methods for screening microbes for interesting and important compounds. This book presents strategies and methods for identifying novel molecules with several types of biological activity. In addition, the book discusses the identification of microbial compounds of agrochemical importance, presents information on chemical screening methods, and concludes with chapters on microbial strain selection, fermentation technology, and genetic engineering of antibiotic-producing microorganisms. This book will be of great interest to scientists working in the very active and competitive fields of antibiotic and agrochemical discovery.

Palladium in Organic Synthesis

Palladium in Organic Synthesis PDF Author: Jiro Tsuji
Publisher: Springer Science & Business Media
ISBN: 9783540239826
Category : Science
Languages : en
Pages : 348

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Book Description
with contributions by numerous experts

Macrocycles in Drug Discovery

Macrocycles in Drug Discovery PDF Author: Jeremy I Levin
Publisher: Royal Society of Chemistry
ISBN: 1849737010
Category : Medical
Languages : en
Pages : 526

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Book Description
This series provides a comprehensive resource for postgraduate students and for scientists in academia or industry wanting to learn topics outside their own areas of expertise.

Recent Progress in the Chemical Synthesis of Antibiotics

Recent Progress in the Chemical Synthesis of Antibiotics PDF Author: Gabor Lukacs
Publisher: Springer Science & Business Media
ISBN: 3642756174
Category : Science
Languages : en
Pages : 808

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Book Description
The use of antibiotics in the treatment by antibacterial and antifungal chemo therapy, has become standard practice since the end of World War Two and has had an enormous impact on healthcare throughout the world. Compounds belonging to this class have also reached an important place in the medical treatment of human cancer. Although, the discovery of most of these agents came from more or less sophisticated screening programs of soil microrganisms, many of the important antibiotics used today in clinical practice are derived from the original biosynthetic products by the application of often novel and generally elaborated chemical synthetic methodologies. In fact the antibiotics have represented (and still represent) for a generation of organic chemists an endless source of molecular structures whose varied assemblage of carbon atom backbones and chemical functions was beyond any possibility of imagination. Perhaps a similar repertoire of chemotypes was formerly offered by the natural products, namely the alkaloids, the terpenes, the vitamins and hormones as well as the pigments of the animal and plant kingdoms, albeit the chemical arrange ments of the antibiotic molecules appeared much more surprising and diverse to the admiring eyes of cultivated organic chemists. The idea of this book, certainly a landmark in the field, came during the Symposium of EUCHEM on Chemical Synthesis of Antibiotics, that was held at Aussois in Savoy, France (May 2-6, 1988), the initiative being taken by Gabor Lukacs to whom Masaji Ohno readily associated as a co-editor.