Structural Basis of Initiation and Elongation by RNA Polymerase II PDF Download
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Author: Kenneth Dale Westover
Publisher:
ISBN:
Category :
Languages : en
Pages : 222
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Book Description
Author: Kenneth Dale Westover
Publisher:
ISBN:
Category :
Languages : en
Pages : 222
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Book Description
Author: Robert J. White
Publisher: Springer Science & Business Media
ISBN: 3662035189
Category : Science
Languages : en
Pages : 274
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Book Description
This monograph reviews and summarizes the substantial body of work that has been published on the transcription by polymerase III over the past 5 years. Progress in this field has been very rapid since 1993, and this new edition incorporates all the recent developments and offers the reader a highly detailed analysis of the current state of research on this largest and most complex of the eukaryotic RNA polymerases.
Author:
Publisher: Elsevier
ISBN: 0080522416
Category : Science
Languages : en
Pages : 276
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Book Description
Protein Transcription is a key element of cellular and organ regulation. Proteins in Eukaryotic Transcription covers structure and function of all major elements associated with transcription. - Mechanism of RNA polymerase I Transcription - Structure and function of RNA Polymerase II - Structure and function of the TFIID complex - Functional properties of Chromatin Remodeling Enzymes - Posttranslational modification
Author: Jasmin F. Sydow
Publisher:
ISBN:
Category :
Languages : en
Pages : 184
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Book Description
Author: Victor A. Bloomfield
Publisher: Sterling Publishing Company
ISBN: 9780935702491
Category : Science
Languages : en
Pages : 854
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Book Description
Providing a comprehensive account of the structures and physical chemistry properties of nucleic acids, with special emphasis on biological function, this text has been organized to meet the needs of those who have only a basic understanding of physical chemistry and molecular biology.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Arthur Kornberg
Publisher: Harvard University Press
ISBN: 9780674307766
Category : Biography & Autobiography
Languages : en
Pages : 356
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Book Description
Winner of the American Medical Writers' Association Book Award, this volume describes, with observations on the process of scientific research, the author's successive research problems, the challenges they presented and the ultimate accomplishments thatresulted.
Author: Wolfram Saenger
Publisher: Springer Science & Business Media
ISBN: 1461251907
Category : Science
Languages : en
Pages : 574
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Book Description
New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical ther modynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the grad uate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses. CHARLES R. CANTOR New York Preface This monograph is based on a review on polynucleotide structures written for a book series in 1976.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 37
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Book Description
The purpose of the proposed research was to provide a structural basis for understanding the mechanism of transcription, its regulation, and altered regulation as occurs in tumor cells. The goal of the proposed research is to determine the X-ray structure of RNA Polymerase II in the midst of transcribing RNA from a DNA template. Despite challenges involved in this project, a major achievement is at hand. Firstly, a mainchain model of RNA Polymerase II with distinct features directly involved in transcription has been achieved. Secondly, two biochemical systems allowing for the generation of elongation complexes and thirdly the collection of X-ray diffraction data sets of two different elongation complexes has been achieved. Structural data derived from molecular replacement with the mainchain model shows that in the elongation complex, a key domain moves relative to the mainchain model, and acts as a clamp for nucleic acids in the active site cleft. A refined model of polymerase will shortly be available for molecular replacement with the elongation diffraction data, which should allow for the completion of the main goal of this project.
Author: Robert Landick
Publisher: Royal Society of Chemistry
ISBN: 1839160667
Category : Science
Languages : en
Pages : 295
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Book Description
To thrive, every living cell must continuously gauge and respond to changes in its environment. These changes are ultimately implemented by modulating gene expression, a process that relies on transcription by Nature’s most multivalent molecular machine, the RNA polymerase. This book covers progress made over the past decade understanding how this machine functions to compute the cellular state, from the atomistic structural level responsible for chemistry to the integrative level at which RNA polymerase interacts with the other key molecular machineries of the cell.
