Precision Medicine in Stroke

Precision Medicine in Stroke PDF Author: Ana Catarina Fonseca
Publisher: Springer
ISBN: 9783030707637
Category : Medical
Languages : en
Pages : 0

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Book Description
This book provides a comprehensive coverage of the state of the art in precision medicine in stroke. It starts by explaining and giving general information about precision medicine. Current applications in different strokes types (ischemic, haemorrhagic) are presented from diagnosis to treatment. In addition, ongoing research in the field (early stroke diagnosis and estimation of prognosis) is extensively discussed. The final part provides an in-depth discussion of how different interdisciplinary areas like artificial intelligence, molecular biology and genetics are contributing to this area. Precision Medicine in Stroke provides a practical approach to each chapter, reinforcing clinical applications and presenting clinical cases. This book is intended for all clinicians that interact with stroke patients (neurologists, internal medicine doctors, general practitioners, neurosurgeons), students and basic researchers.

Precision Medicine in Stroke

Precision Medicine in Stroke PDF Author: Ana Catarina Fonseca
Publisher: Springer
ISBN: 9783030707637
Category : Medical
Languages : en
Pages : 0

Get Book Here

Book Description
This book provides a comprehensive coverage of the state of the art in precision medicine in stroke. It starts by explaining and giving general information about precision medicine. Current applications in different strokes types (ischemic, haemorrhagic) are presented from diagnosis to treatment. In addition, ongoing research in the field (early stroke diagnosis and estimation of prognosis) is extensively discussed. The final part provides an in-depth discussion of how different interdisciplinary areas like artificial intelligence, molecular biology and genetics are contributing to this area. Precision Medicine in Stroke provides a practical approach to each chapter, reinforcing clinical applications and presenting clinical cases. This book is intended for all clinicians that interact with stroke patients (neurologists, internal medicine doctors, general practitioners, neurosurgeons), students and basic researchers.

Stroke Biomarkers

Stroke Biomarkers PDF Author: Philip V. Peplow
Publisher: Humana
ISBN: 9781493996810
Category : Medical
Languages : en
Pages : 0

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Book Description
This volume presents the latest data on recent achievements in new and emerging technologies for stroke biomarkers and innovations in stroke assessment. The topics discussed in this book explore the role of upcoming biomarkers in different types of stroke, and explores techniques that will allow researchers to be more effective when approaching clinical management and patient care. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to ensure successful results in the laboratory. Cutting-edge and comprehensive, Stroke Biomarkers is a valuable resource for both experimental and clinical scientists interested in expanding their knowledge in the field of stroke research.

Blood-Based Biomarkers in Acute Ischemic Stroke and Hemorrhagic Stroke

Blood-Based Biomarkers in Acute Ischemic Stroke and Hemorrhagic Stroke PDF Author: Robert G. Kowalski
Publisher: Frontiers Media SA
ISBN: 2889745449
Category : Medical
Languages : en
Pages : 348

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Book Description
Topic Editor, Prof. Heinrich Audebert, received funding from institutional funding by Roche Diagnostics International Ltd. and the Berlin Future Funds. The other Topic Editors declare no competing interests with regard to the Research Topic subject.

Neuroinflammation in Stroke

Neuroinflammation in Stroke PDF Author: Ulrich Dirnagl
Publisher: Springer Science & Business Media
ISBN: 3662054264
Category : Medical
Languages : en
Pages : 248

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Book Description
The successful treatment of acute stroke remains one of the major challenges in clinical medicine. Over the last decades, the understanding of stroke pathophysiology has greatly improved, while the therapeutic options in stroke therapy remain very limited. Today, hyperacute mechanisms of damage, such as excitotoxicity, can be discriminated from delayed ones, such as inflammation and apoptosis. Targeting of inflammation has already been successfully applied in various stroke models, but translation into a clinically efficacious strategy has not been achieved so far. In this book, leading experts in basic cerebrovascular research as well as stroke treatment review the current evidence for and against an important role for inflammation in stroke, and explore the potential of treating or modulating inflammation in stroke therapy.

The Handbook of Biomarkers

The Handbook of Biomarkers PDF Author: Kewal K. Jain
Publisher: Humana Press
ISBN: 1493974319
Category : Science
Languages : en
Pages : 765

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Book Description
Involved in nearly every therapeutic area, particularly cancer, biomarkers have experienced tremendous advances since the first edition of this book, both in the discovery of biomarkers and in their applications. To aid in this imperative research, Prof. Kewal K. Jain’s Handbook of Biomarkers, Second Edition features a full revision and additional chapters to thoroughly describe many different types of biomarkers and their discovery using various "-omics" technologies, along with the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials. With biomarkers described first according to technologies and then according to various diseases, this detailed book features the key correlations between diseases and classifications of biomarkers, which provides the reader with a guide to sort out current and future biomarkers. Comprehensive and cutting-edge, The Handbook of Biomarkers, Second Edition serves as a vital guide to furthering our understanding of biomarkers, which, by facilitating the combination of therapeutics with diagnostics, promise to play an important role in the development of personalized medicine, one of the most important trends in healthcare today.

Broken Movement

Broken Movement PDF Author: John W. Krakauer
Publisher: MIT Press
ISBN: 0262545837
Category : Medical
Languages : en
Pages : 288

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Book Description
An account of the neurobiology of motor recovery in the arm and hand after stroke by two experts in the field. Stroke is a leading cause of disability in adults and recovery is often difficult, with existing rehabilitation therapies largely ineffective. In Broken Movement, John Krakauer and S. Thomas Carmichael, both experts in the field, provide an account of the neurobiology of motor recovery in the arm and hand after stroke. They cover topics that range from behavior to physiology to cellular and molecular biology. Broken Movement is the only accessible single-volume work that covers motor control and motor learning as they apply to stroke recovery and combines them with motor cortical physiology and molecular biology. The authors cast a critical eye at current frameworks and practices, offer new recommendations for promoting recovery, and propose new research directions for the study of brain repair. Krakauer and Carmichael discuss such subjects as the behavioral phenotype of hand and arm paresis in human and non-human primates; the physiology and anatomy of the motor system after stroke; mechanisms of spontaneous recovery; the time course of early recovery; the challenges of chronic stroke; and pharmacological and stem cell therapies. They argue for a new approach in which patients are subjected to higher doses and intensities of rehabilitation in a more dynamic and enriching environment early after stroke. Finally they review the potential of four areas to improve motor recovery: video gaming and virtual reality, invasive brain stimulation, re-opening the sensitive period after stroke, and the application of precision medicine.

Biomarkers for Traumatic Brain Injury

Biomarkers for Traumatic Brain Injury PDF Author: Svetlana Dambinova
Publisher: Royal Society of Chemistry
ISBN: 1849733899
Category : Medical
Languages : en
Pages : 247

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Book Description
Due to injuries sustained in sports and in combat, interest in traumatic brain injury (TBI) has never been greater. This book will fulfill a gap in understanding of what is occurring in the brain following injury that can subsequently be detected in biological fluids and imaging.

Computer Aided Intervention and Diagnostics in Clinical and Medical Images

Computer Aided Intervention and Diagnostics in Clinical and Medical Images PDF Author: J. Dinesh Peter
Publisher: Springer
ISBN: 3030040615
Category : Technology & Engineering
Languages : en
Pages : 292

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Book Description
This book is a compendium of the ICCMIA 2018 proceedings, which provides an ideal reference for all medical imaging researchers and professionals to explore innovative methods and analyses on imaging technologies for better prospective patient care. This work serves as an exclusive source for new computer assisted clinical and medical developments in imaging diagnosis, intervention and analysis. It includes articles on computer assisted medical scanning techniques, computer-aided diagnosis, robotic surgery and imaging, imaging genomics, clinically-oriented imaging physics and informatics, augmented-reality medical visualization, imaging modalities, computerized radiology, oncology, and surgery. Moreover, information on non-medical imaging that has medical applications such as multi-photon microscopy and confocal, photoacoustic imaging, optical microendoscope, infra-red radiation, and other imaging modalities is also represented.

Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease

Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309157277
Category : Medical
Languages : en
Pages : 335

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Book Description
Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, but that is not always the case. The IOM recommends that the FDA adopt a consistent scientific framework for biomarker evaluation in order to achieve a rigorous and transparent process.

Biomarkers in Alzheimer's Disease

Biomarkers in Alzheimer's Disease PDF Author: Tapan Khan
Publisher: Academic Press
ISBN: 0128051477
Category : Psychology
Languages : en
Pages : 278

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Book Description
Biomarkers in Alzheimer's Disease provides a comprehensive overview of all modalities of Alzheimer's disease biomarkers, including neuroimaging, cerebrospinal fluid, genomic, and peripheral systems. Each chapter integrates molecular/cellular abnormality due to Alzheimer's disease and technological advancement of biomarkers techniques. The book is ideal for clinical neuroscience and molecular/cellular neuroscience researchers, psychiatrists, and allied healthcare practitioners involved in the diagnosis and management of patients with cognitive impairment and Alzheimer's disease, and for differential diagnosis of Alzheimer's disease with other non-Alzheimer's dementia. - Presents a comprehensive overview detailing all modalities of Alzheimer's disease biomarkers - Written for neuroscience researchers and clinicians studying or treating patients with Alzheimer's Disease - Integrates, in each chapter, the molecular/cellular abnormality due to Alzheimer's disease and the technological advancement of biomarkers techniques