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Author: Mary V. Solanto
Publisher: Oxford University Press, USA
ISBN: 9780195133714
Category : Medical
Languages : en
Pages : 434
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Book Description
Stimulant drugs are widely used in the treatment of ADHD in children and adults. Hundreds of studies over the past 60 years have demonstrated their effectiveness in improving attention span, increasing impulse control, and reducing hyperactivity and restlessness. Despite widespread interest in these compounds, however, their mechanisms of action in the central nervous system have remained poorly understood. Recent advances in the basic and clinical neurosciences now afford the possibility of elucidating these mechanisms. The current volume is the first to bring this expanding knowledge to bear on the central question of why and how stimulants exert their therapeutic effects. The result is a careful, comprehensive, and insightful integration of material by well-known scientists that significantly advances our understanding of stimulant effects and charts a course for future research. Part I presents a comprehensive description of the clinical features of ADHD and the clinical response to stimulants. Part II details the cortical and subcortical neuroanatomy and functional neurophysiology of dopamine and norepinephrine systems with respect to the regulation of attention, arousal, activity, and impulse control and the effects of stimulants on these systems. Part III is devoted to clinical research, including recent studies of neuroimaging, genetics, pharmacodynamic and pharmacokinetic properties of stimulants, effects on cognitive functions, neurophysiological effects in humans with and without ADHD and in non-human primates, and comparison of stimulants and non-stimulants in the treatment of ADHD. Part IV is a masterful synthesis that presents alternative models of stimulant drug action and generates key hypotheses for continued research. The volume will be of keen interest to researchers and clinicians in psychiatry, psychology, and neurology, neuroscientists studying stimulants, and those pursuing development of new drugs to treat ADHD.
Author: Mary V. Solanto
Publisher: Oxford University Press, USA
ISBN: 9780195133714
Category : Medical
Languages : en
Pages : 434
Get Book
Book Description
Stimulant drugs are widely used in the treatment of ADHD in children and adults. Hundreds of studies over the past 60 years have demonstrated their effectiveness in improving attention span, increasing impulse control, and reducing hyperactivity and restlessness. Despite widespread interest in these compounds, however, their mechanisms of action in the central nervous system have remained poorly understood. Recent advances in the basic and clinical neurosciences now afford the possibility of elucidating these mechanisms. The current volume is the first to bring this expanding knowledge to bear on the central question of why and how stimulants exert their therapeutic effects. The result is a careful, comprehensive, and insightful integration of material by well-known scientists that significantly advances our understanding of stimulant effects and charts a course for future research. Part I presents a comprehensive description of the clinical features of ADHD and the clinical response to stimulants. Part II details the cortical and subcortical neuroanatomy and functional neurophysiology of dopamine and norepinephrine systems with respect to the regulation of attention, arousal, activity, and impulse control and the effects of stimulants on these systems. Part III is devoted to clinical research, including recent studies of neuroimaging, genetics, pharmacodynamic and pharmacokinetic properties of stimulants, effects on cognitive functions, neurophysiological effects in humans with and without ADHD and in non-human primates, and comparison of stimulants and non-stimulants in the treatment of ADHD. Part IV is a masterful synthesis that presents alternative models of stimulant drug action and generates key hypotheses for continued research. The volume will be of keen interest to researchers and clinicians in psychiatry, psychology, and neurology, neuroscientists studying stimulants, and those pursuing development of new drugs to treat ADHD.
Author: Nancy J. Wesensten
Publisher: Cambridge University Press
ISBN: 1107004098
Category : Health & Fitness
Languages : en
Pages : 287
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Book Description
Provides a critical review of stimulant medication literature regarding stimulant efficacy for restoring/maintaining cognition during sleep loss.
Author: Paula Johanson
Publisher: The Rosen Publishing Group, Inc
ISBN: 1448854830
Category : Juvenile Nonfiction
Languages : en
Pages : 66
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Book Description
Describes the effects of amphetamines and stimulants and provides information about drug testing, dependence and withdrawal, and finding treatment.
Author: James White
Publisher: Woodhead Publishing
ISBN: 0128221607
Category : Science
Languages : en
Pages : 505
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Book Description
Microbiome Stimulants for Crops: Mechanisms and Applications provides the latest developments in the real-world development and application of these crop management alternatives in a cost-effective, yield protective way. Sections address questions of research, development and application, with insights into recent legislative efforts in Europe and the United States. The book includes valuable information regarding mechanisms and the practical information needed to support the growing microbial inoculant and biostimulant industry, thus helping focus scientific research in new directions. Provides methods for finding and testing endophytic and growth promotional microbes Explains the mechanisms of microbes and other biostimulant function in promoting plant growth Evaluates methods for treatments of plants with microbes and microbiome stimulants Identifies areas for new research
Author: Rudi Matthee
Publisher: Princeton University Press
ISBN: 1400832608
Category : History
Languages : en
Pages : 367
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Book Description
From ancient times to the present day, Iranian social, political, and economic life has been dramatically influenced by psychoactive agents. This book looks at the stimulants that, as put by a longtime resident of seventeenth-century Iran, Raphaël du Mans, provided Iranians with damagh, gave them a "kick," got them into a good mood. By tracing their historical trajectory and the role they played in early modern Iranian society (1500-1900), Rudi Matthee takes a major step in extending contemporary debates on the role of drugs and stimulants in shaping the modern West. At once panoramic and richly detailed, The Pursuit of Pleasure examines both the intoxicants known since ancient times--wine and opiates--and the stimulants introduced later--tobacco, coffee, and tea--from multiple angles. It brings together production, commerce, and consumption to reveal the forces behind the spread and popularity of these consumables, showing how Iranians adapted them to their own needs and tastes and integrated them into their everyday lives. Matthee further employs psychoactive substances as a portal for a set of broader issues in Iranian history--most notably, the tension between religious and secular leadership. Faced with reality, Iran's Shi`i ulama turned a blind eye to drug use as long as it stayed indoors and did not threaten the social order. Much of this flexibility remains visible underneath the uncompromising exterior of the current Islamic Republic.
Author: H. Thomas Jr. Milhorn
Publisher: Springer Science & Business Media
ISBN: 1461234182
Category : Medical
Languages : en
Pages : 370
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Book Description
The author has organized basic, core information on the diagnosis, treatment and prevention of chemical dependence into a readily understandable format. His approach teaches the physician what steps to take from a practical point of view: how to prevent addiction in the first place, how to diagnose the condition, how to aid the family get the addict into treatment, and how to increase the chances of long-term recovery. The book is divided into three sections. The first section covers basic definitions and concepts. The second section describes the pharmacology of the various psychoactive substances: depressants, opioids, stimulants, cannabinoids, hallucinogens, phencyclidines, and inhalants. The third section discusses chemical dependence in special groups: women, adolescents, the elderly, ethnic minorities, dual diagnosis patients, HIV- positive patients, and impaired physicians.
Author: Neil Kaplowitz
Publisher: CRC Press
ISBN: 0203909127
Category : Medical
Languages : en
Pages : 784
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Book Description
Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.
Author: George F. Koob
Publisher: Academic Press
ISBN: 0128169915
Category : Psychology
Languages : en
Pages : 264
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Book Description
A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction are detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Psychostimulants, Volume 2 in the series, explores the molecular and cellular systems in the brain responsible for psychostimulant addiction, including both direct/indirect sympathomimetics and nonsympathomimetics. This volume introduces the readers to the history of psychostimulant use. The authors clearly differentiate the neurobiological effects into three distinct stages of the addiction cycle: binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Highlights recent advances in psychostimulant addiction Includes neurocircuitry, cellular and molecular neurobiological mechanisms of psychostimulant addiction Defines the abuse and addiction potentials of both direct and indirect sympathomimetics and nonsympathomimetics
Author: Peter Breggin
Publisher: Da Capo Press
ISBN: 0738212105
Category : Health & Fitness
Languages : en
Pages : 450
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Book Description
Millions of children take Ritalin for Attention-Deficit Hyperactivity Disorder. The drug's manufacturer, Novartis, claims that Ritalin is the "solution" to this widespread problem. But hidden behind the well-oiled public-relations machine is a potentially devastating reality: children are being given a drug that can cause the same bad effects as amphetamine and cocaine, including behavioral disorders, growth suppression, neurological tics, agitation, addiction, and psychosis. Talking Back to Ritalin uncovers these and other startling facts and translates the research findings for parents and doctors alike. An advocate for education not medication, Dr. Breggin empowers parents to channel distracted, disenchanted, and energetic children into powerful, confident, and brilliant members of the family and society.
Author: Thomas R. Kosten
Publisher: American Psychiatric Pub
ISBN: 1585624071
Category : Medical
Languages : en
Pages : 236
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Book Description
This volume provides a summary of the most current information about stimulant dependence and its treatment. In addition, it sheds light on how the epidemiology of cocaine, amphetamine and methamphetamine abuse and dependence have substantial differences in geographic distribution, and how treatments are evolving to help these complex patients benefit from emerging pharmacological and behavioral therapies. Also, the editors provide literature that discusses, among many topics: the recent shift to more humane responses within the criminal justice system that is useful in obtaining treatment for the estimated 1.6 million cocaine and half-million methamphetamine users who abuse these drugs each day in the U.S., and also key treatment considerations, such as HIV comorbidity and polydrug abuse.
