Author: Wayne J Rogers
Publisher: Smithers Rapra
ISBN: 1909030708
Category : Medical
Languages : en
Pages : 562
Get Book Here
Book Description
The collection of topics in the second volume of this book challenges the reader to think beyond standard methods and question why certain current procedures remain static while technological advances abound in other aspects of sterilisation technology. By small means, better practices may come to pass to help answer some of the residual healthcare sterilisation and nosocomial infection queries: What are some of the current challenges in healthcare sterilisation, and how can they be handled? What are some of the acceptable current non-traditional sterilisation methods, challenging alternatives, and novel modalities? What are some of the packaging, validation and statistical considerations of sterilisation practices? How does design-of-product and packaging interrelate with sterilisation processing? Are the current sterility media and practices optimal for recovery of more modified and more resistant viable organism entities and product? Are there increased sterility and product quality needs with new types of implantables and technological advances within the three dimensional combinations of diagnostics, drug release and challenging medical devices?
Author: Wayne J. Rogers
Publisher: iSmithers Rapra Publishing
ISBN: 9781859574904
Category : Medical instruments and apparatus
Languages : en
Pages : 344
Get Book Here
Book Description
Sterilisation has always been challenging but sterilisation of healthcare products and polymers, especially together is an even greater challenge - how do you sterilise without adversely affecting the end use or the end user? This book discusses all the sterilisation methods used for polymeric healthcare products both traditional and new.
Author: Sophie Lerouge
Publisher: Elsevier
ISBN: 0857096265
Category : Medical
Languages : en
Pages : 347
Get Book Here
Book Description
The effective sterilisation of any material or device to be implanted in or used in close contact with the human body is essential for the elimination of harmful agents such as bacteria. Sterilisation of biomaterials and medical devices reviews established and commonly used technologies alongside new and emerging processes.Following an introduction to the key concepts and challenges involved in sterilisation, the sterilisation of biomaterials and medical devices using steam and dry heat, ionising radiation and ethylene oxide is reviewed. A range of non-traditional sterilisation techniques, such as hydrogen peroxide gas plasma, ozone and steam formaldehyde, is then discussed together with research in sterilisation and decontamination of surfaces by plasma discharges. Sterilisation techniques for polymers, drug-device products and tissue allografts are then reviewed, together with antimicrobial coatings for 'self-sterilisation' and the challenge presented by prions and endotoxins in the sterilisation of reusable medical devices. The book concludes with a discussion of future trends in the sterilisation of biomaterials and medical devices.With its distinguished editors and expert team of international contributors, Sterilisation of biomaterials and medical devices is an essential reference for all materials scientists, engineers and researchers within the medical devices industry. It also provides a thorough overview for academics and clinicians working in this area. - Reviews established and commonly used technologies alongside new and emerging processes - Introduces and reviews the key concepts and challenges involved in sterilisation - Discusses future trends in the sterilisation of biomaterials and medical devices
Author: Tim Sandle
Publisher: Elsevier
ISBN: 1908818638
Category : Medical
Languages : en
Pages : 370
Get Book Here
Book Description
Failure to adequately control any microbial challenge associated within process or product by robust sterilisation will result in a contaminated marketed product, with potential harm to the patient. Sterilisation is therefore of great importance to healthcare and the manufacturers of medical devices and pharmaceuticals. Sterility, sterilisation and sterility assurance for pharmaceuticals examines different means of rendering a product sterile by providing an overview of sterilisation methods including heat, radiation and filtration. The book outlines and discusses sterilisation technology and the biopharmaceutical manufacturing process, including aseptic filling, as well as aspects of the design of containers and packaging, as well as addressing the cleanroom environments in which products are prepared. Consisting of 18 chapters, the book comprehensively covers sterility, sterilisation and microorganisms; pyrogenicity and bacterial endotoxins; regulatory requirements and good manufacturing practices; and gamma radiation. Later chapters discuss e-beam; dry heat sterilisation; steam sterilisation; sterilisation by gas; vapour sterilisation; and sterile filtration, before final chapters analyse depyrogenation; cleanrooms; aseptic processing; media simulation; biological indicators; sterility testing; auditing; and new sterilisation techniques. - Covers the main sterilisation methods of physical removal, physical alteration and inactivation - Includes discussion of medical devices, aseptically filled products and terminally sterilised products - Describes bacterial, pyrogenic, and endotoxin risks to devices and products
Author: Silvia I. Acosta-Gnass
Publisher: Pan Amer Health Org
ISBN: 9789275129265
Category : Medical
Languages : en
Pages : 167
Get Book Here
Book Description
This updated sterilisation manual informs health workers about the simple protocols and procedures that have been developed to prevent hospital-acquired infections both inside and outside the sterilisation plant. The guidelines included in this manual show the steps to follow in cleaning, preparing, sterilizing, storing and transporting hospital equipment so as to obtain sterile material. It is very important to be aware of this information in order to provide patients with safe health care.
Author: Jeanne Moldenhauer
Publisher: CRC Press
ISBN: 1351217011
Category : Medical
Languages : en
Pages : 254
Get Book Here
Book Description
This book describes various methods of decontamination and how the methods work. There is a discussion of the various cleaning and disinfection methods utilized, along with details of how to qualify these methods. It also describes new technologies that may be useful in the battle for decontamination across industries. Finally, this book provides a single resource on how one can address contamination issues for a variety of manufacturing processes and industries. Explores new technologies that may be useful in the battle for decontamination Examines various methods of decontamination and how the methods work Addresses contamination issues for a variety of manufacturing processes and industries Describes how to detect contaminants as well as how to deal with contaminants that are present Includes methods for both decontamination (reaction) and preventing contamination (proactive)
Author:
Publisher: Academic Press
ISBN: 0128144556
Category : Medical
Languages : en
Pages : 974
Get Book Here
Book Description
The Future of Pharmaceutical Product Development and Research examines the latest developments in the pharmaceutical sciences, also highlighting key developments, research and future opportunities. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of the product development phase of drug discovery and drug development. Each chapter covers fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and the pharmaceutical industry. The book focuses on excipients, radiopharmaceuticals, and how manufacturing should be conducted in an environment that follows Good Manufacturing Practice (GMP) guidelines. Researchers and students will find this book to be a comprehensive resource for those working in, and studying, pharmaceuticals, cosmetics, biotechnology, foods and related industries. Provides an overview of practical information for clinical trials Outlines how to ensure an environment that follows Good Manufacturing Practice (GMP) Examines recent developments and suggests future directions for drug production methods and techniques
Author: Sandeep Nema
Publisher: CRC Press
ISBN: 0429576838
Category : Business & Economics
Languages : en
Pages : 1125
Get Book Here
Book Description
Parenteral Medications is an authoritative, comprehensive reference work on the formulation and manufacturing of parenteral dosage forms, effectively balancing theoretical considerations with practical aspects of their development. Previously published as a three-volume set, all volumes have been combined into one comprehensive publication that addresses the plethora of changes in the science and considerable advances in the technology associated with these products and routes of administration. Key Features: Provides a comprehensive reference work on the formulation and manufacturing of parenteral dosage forms Addresses changes in the science and advances in the technology associated with parenteral medications and routes of administration Includes 13 new chapters and updated chapters throughout Contains the contributors of leading researchers in the field of parenteral medications Uses full color detailed illustrations, enhancing the learning process The fourth edition not only reflects enhanced content in all the chapters but also highlights the rapidly advancing formulation, processing, manufacturing parenteral technology including advanced delivery and cell therapies. The book is divided into seven sectionss: Section 1 - Parenteral Drug Administration and Delivery Devices; Section 2 - Formulation Design and Development; Section 3 - Specialized Drug Delivery Systems; Section 4 - Primary Packaging and Container Closure Integrity; Section 5 - Facility Design and Environmental Control; Section 6 - Sterilization and Pharmaceutical Processing; Section 7 - Quality Testing and Regulatory Requirements
Author: Ramon Z Shaban
Publisher: Elsevier Health Sciences
ISBN: 0729588351
Category : Medical
Languages : en
Pages : 979
Get Book Here
Book Description
Infection prevention and control (IPC) is everybody's responsibility. Healthcare-associated Infections in Australia is the first Australian text to address the challenges posed by infectious diseases and healthcareassociated infections (HAIs) for all members of the multidisciplinary healthcare team. Drawing on the expertise of a wide author team, and based on current research, this important and comprehensive text provides a clear pathway for the reader to increase their knowledge and understanding of IPC. The text is designed for both students and practising clinicians, and is presented in two sections - Principles and Practice - for ease of use. With IPC principles and guidelines now embedded into all health-related curricula, and mandated by standards and guidelines across all areas of healthcare, this is a book no health professional should miss. - Includes practice tips, case studies and video-based learning materials providing real-life examples across more than 20 health professions - Suitable for increasing IPC knowledge across all members of the multidisciplinary team. Content is pitched at different levels, with examples ranging from novice to expert - Aligned to the Australian National Infection Control Guidelines 2019 and the NSQHS Standard Preventing and Controlling Healthcare Associated Infections, as well as the nine hospital-acquired complication (HAC) HAIs addressed in specific chapters - Endorsed by the Australian College for Infection Prevention and Control (ACIPC) and the Australian Society for Infectious Diseases (ASID) - Supported by a companion text, Epidemiology of Healthcare-associated Infections in Australia, providing data on the epidemiology of healthcare-associated surveillance in Australia Instructor and Student resources on Evolve: Multiple Choice Questions Case Studies Abbreviations and Glossary Useful Websites / Resources Video-based learning materials
Author: British Standards Institute Staff
Publisher:
ISBN: 9780580779336
Category :
Languages : en
Pages : 74
Get Book Here
Book Description
Sterilization (hygiene), Sterile equipment, Sterilizers, Medical equipment, Medical instruments, Process control, Quality control, Verification
