A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy PDF Author: Mariappan Rajan
Publisher: Academic Press
ISBN: 0128244844
Category : Medical
Languages : en
Pages : 330

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Book Description
A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy examines drug carrier development for controlled, targeted, pH and stimuli responsive drug releases for tuberculosis. The book provides in-depth information about mycobacterium tuberculosis, tuberculosis formation, and synthetic procedures for carrier synthesis, characterizations and mechanistic approaches. Key topics include the properties and functions of nanomedicines and how they might be applied for clinical diagnosis and treatment. Emphasis is placed on the basic fundamentals, biomaterial formulations, design principles, fabrication techniques, and transitioning bench-to-bed clinical applications. This book is useful for new researchers who focus on nanomedicine, stem cell therapy and bone tissue engineering. In addition, it introduces experienced researchers and clinicians to key trends, thus increasing their knowledge in drug discovery for tuberculosis and nanomedicine. - Features the most notable uses of drug for tuberculosis treatment, including novel advances in materials - Assesses new agents and chemical compounds against tuberculosis - Examines the interaction of new technologies to discover ways to treat tuberculosis more effectively and efficiently

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy PDF Author: Mariappan Rajan
Publisher: Academic Press
ISBN: 0128244844
Category : Medical
Languages : en
Pages : 330

Get Book Here

Book Description
A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy examines drug carrier development for controlled, targeted, pH and stimuli responsive drug releases for tuberculosis. The book provides in-depth information about mycobacterium tuberculosis, tuberculosis formation, and synthetic procedures for carrier synthesis, characterizations and mechanistic approaches. Key topics include the properties and functions of nanomedicines and how they might be applied for clinical diagnosis and treatment. Emphasis is placed on the basic fundamentals, biomaterial formulations, design principles, fabrication techniques, and transitioning bench-to-bed clinical applications. This book is useful for new researchers who focus on nanomedicine, stem cell therapy and bone tissue engineering. In addition, it introduces experienced researchers and clinicians to key trends, thus increasing their knowledge in drug discovery for tuberculosis and nanomedicine. - Features the most notable uses of drug for tuberculosis treatment, including novel advances in materials - Assesses new agents and chemical compounds against tuberculosis - Examines the interaction of new technologies to discover ways to treat tuberculosis more effectively and efficiently

3D Printing and Bioprinting for Pharmaceutical and Medical Applications

3D Printing and Bioprinting for Pharmaceutical and Medical Applications PDF Author: Jose Luis Pedraz Muñoz
Publisher: CRC Press
ISBN: 1000957543
Category : Medical
Languages : en
Pages : 333

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Book Description
The increasing availability and decreasing costs of 3D printing and bioprinting technologies are expanding opportunities to meet medical needs. 3D Printing and Bioprinting for Pharmaceutical and Medical Applications discusses emerging approaches related to these game-changer technologies in such areas as drug development, medical devices, and bioreactors. Key Features: Offers an overview of applications, the market, and regulatory analysis Analyzes market research of 3D printing and bioprinting technologies Reviews 3D printing of novel pharmaceutical dosage forms for personalized therapies and for medical devices, as well as the benefits of 3D printing for training purposes Covers 3D bioprinting technology, including the design of polymers and decellularized matrices for bio-inks development, elaboration of 3D models for drug evaluation, and 3D bioprinting for musculoskeletal, cardiovascular, central nervous system, ocular, and skin applications Provides risk-benefit analysis of each application Highlights bioreactors, regulatory aspects, frontiers, and challenges This book serves as an ideal reference for students, researchers, and professionals in materials science, bioengineering, the medical industry, and healthcare.

Pharmaceutical Formulations for Older Patients

Pharmaceutical Formulations for Older Patients PDF Author: Mine Orlu
Publisher: Springer Nature
ISBN: 3031358112
Category : Science
Languages : en
Pages : 294

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Book Description
Pharmaceutical formulation design affects patient acceptability/adherence and pharmacokinetics of the drug. This is particularly important for older patients because of the physiological changes due to ageing and clinical/social circumstances related to medicine taking. This book provides a comprehensive review in the design of formulations to meet the needs of older patients. An overview of the key clinical, social and pharmaceutical factors affecting medication optimization, safety and acceptability in older adults is included, followed by patient-centric considerations including regulatory requirements, dosage form design and human factor studies. Advanced pharmaceutical technologies are discussed for their potential use in older adults such as 3D printing, long-acting oral formulations and novel vaccine technologies. The unique focus of the book will be of interest to pharmaceutical scientists in both industry and academia in searching for better formulations for older patients.

Aerosols Handbook

Aerosols Handbook PDF Author: Lev S. Ruzer
Publisher: CRC Press
ISBN: 1439855102
Category : Technology & Engineering
Languages : en
Pages : 669

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Book Description
With the rapid growth of the nanotechnology industry, the need to understand the biological effects of aerosol exposure has become increasingly important. Featuring contributions by leading experts in the field, Aerosols Handbook: Measurement, Dosimetry, and Health Effects, Second Edition offers an up-to-date overview of many aspects of aerosols, from properties to health effects and epidemiology. Covering indoor, outdoor, industrial, medical, pharmaceutical, and radioactive aerosols, this book explores aerosol dosimetry by defining terms such as exposure and dose. In addition, it looks at nanometer particles, the mechanism of aerosol deposition in the lungs, and modeling deposition with a corresponding uncertainty in risk assessment. The text also emphasizes the importance of accurate aerosol measurements, particularly breathing zone exposure assessments. Examining radioactive aerosols, the book discusses lessons learned from nuclear accidents, radon and thoron, and long-lived radionuclides in the environment. It brings together research on both radioactive and nonradioactive aerosols, supplying readers with a more complete view of how aerosols behave in the lungs. New in This Edition Five new chapters that address the safety of nanomaterials, dealing with nanoparticle cell penetration, high aspect ratio nanomaterials, nanoaerosols in drug delivery, risk assessment, and health effects New chapters on atmospheric pollution related to climate change, chemical analyses of particle filter deposits, and classical nucleation theory New data on measurement, dosimetry, and health effects Updated throughout, this second edition continues to be an essential resource for those who study exposure, dosages, and toxicity to develop treatments for exposure, reduce air pollution, and establish better safety regulations, particularly in industries using nanotechnologies.

3D & 4D Printing Methods for Pharmaceutical Manufacturing and Personalised Drug Delivery

3D & 4D Printing Methods for Pharmaceutical Manufacturing and Personalised Drug Delivery PDF Author: Dimitrios Lamprou
Publisher: Springer Nature
ISBN: 3031341198
Category : Medical
Languages : en
Pages : 329

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Book Description
New materials and manufacturing techniques are emerging with potential to address the challenges associated with the manufacture of pharmaceutical systems that will teach new tricks to old drugs. 3D printing (3DP) is a technique that can used for the manufacturing of dosage forms, and especially targeting paediatric and geriatric formulations, as permits the fabrication of high degrees of complexity with great reproducibility, in a fast and cost-effective fashion, and offers a new paradigm for the direct manufacture of personalised dosage forms. The book is covering the basics behind each additive manufacturing (AM) method, current applications in pharmaceutics for each 3DP method, and case studies (examples) from a teaching perspective, targeting undergraduate (UG) and postgraduate (PG) students. A unique to this book is the integration of studies based upon the use of different AM technologies, which designed to reinforce importance printing parameters and material considerations. The book includes case studies or multiple-choice questions (MCQs), which allow application of the content in a flipped-classroom.

Biomaterials Fabrication and Processing Handbook

Biomaterials Fabrication and Processing Handbook PDF Author: Paul K. Chu
Publisher: CRC Press
ISBN: 0849379741
Category : Medical
Languages : en
Pages : 720

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Book Description
This volume focuses on a variety of production and processing aspects of the latest biomaterials. It discusses how scaffolds are used in tissue engineering and describes common implant materials, such as hard tissue, blood contacting, and soft tissue. The book also examines the important role nanotechnology plays in the preparation of drugs, protein delivery, tissue engineering, cardiovascular biomaterials, hard tissue replacements, biosensors, and bio-MEMS. With contributions from renowned international experts and extensive reference lists in each chapter, this book provides detailed, practical information to produce biomaterials and employ them in biomedicine.

Nanotechnology-Based Additive Manufacturing

Nanotechnology-Based Additive Manufacturing PDF Author: Kalim Deshmukh
Publisher: John Wiley & Sons
ISBN: 3527835466
Category : Technology & Engineering
Languages : en
Pages : 909

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Book Description
Nanotechnology-Based Additive Manufacturing State-of-the-art overview of additive manufacturing techniques with an emphasis on processes, product designs and applications This book offers a thorough overview of additive manufacturing technologies, including manufacturing requirements, product design, optimization of processes and product parameters to reduce manufacturing costs. It provides a comprehensive and state-of-the-art review on various additive manufacturing technologies, their advantages, shortcomings, potential applications and future directions. Sample topics discussed by the three well-qualified editors on the topic of additive manufacturing include: Areas of application in the fields of electronics, aerospace, construction, automobile, sports and biomedicine Material considerations, the requirement of specific design, fabrication and processing methods Advantages and disadvantages of various 3D printing techniques for the respectively intended applications This book is an immensely valuable resource for researchers working in the field of additive manufacturing or 3D printing, or for developers dealing with the processing and manufacturing of materials and products for advanced technologies.

Manufacturing

Manufacturing PDF Author: Beno Benhabib
Publisher: CRC Press
ISBN: 0824756207
Category : Technology & Engineering
Languages : en
Pages : 550

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Book Description
From concept development to final production, this comprehensive text thoroughly examines the design, prototyping, and fabrication of engineering products and emphasizes modern developments in system modeling, analysis, and automatic control. This reference details various management strategies, design methodologies, traditional production techniques, and assembly applications for clear illustration of manufacturing engineering technology in the modern age. Considers a variety of methods for product design including axiomatic design, design for X, group technology, and the Taguchi method, as well as modern production techniques including laser-beam machining, microlithography.

The Routledge Handbook of Paleopathology

The Routledge Handbook of Paleopathology PDF Author: Anne L. Grauer
Publisher: Taylor & Francis
ISBN: 1000820440
Category : Health & Fitness
Languages : en
Pages : 1013

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Book Description
The Routledge Handbook of Paleopathology provides readers with an overview of the study of ancient disease. The volume begins by exploring current methods and techniques employed by paleopathologists as means to highlight the range of data that can be generated, the types of questions that can be methodologically addressed, our current limitations, and goals for the future. Building on these foundations, the volume introduces a range of diseases and conditions that have been noted in the fossil, archaeological, and historical record, offering readers a foundational understanding of pathological conditions, along with their potential etiologies. Importantly, an evolutionary and highly contextualized assessment of diseases and conditions will be presented in order to demonstrate the need for adopting anthropological, biological, and clinical approaches when exploring the past and interpreting the modern world. The volume concludes with the contextualization of paleopathological research. Chapters highlight ways in which analyses of health and disease in skeletal and mummified remains reflect political and social constructs of the past and present. Health and disease are tackled within evolutionary perspectives across deep time and generationally, and the nuanced interplay between disease and behavior is explored. The volume will be indispensable for archaeologists, bioarchaeologists, and historians, and those in medical fields, as it reflects current scholarship within paleopathology and the field’s impact on our understanding of health and disease in the past, the present, and implications for our future.

Advances in Additive Manufacturing

Advances in Additive Manufacturing PDF Author: Ravi Kant Mittal
Publisher: Elsevier
ISBN: 0323918352
Category : Technology & Engineering
Languages : en
Pages : 522

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Book Description
This edited book is a compilation of scholarly articles on the latest developments in the field of additive manufacturing, discussing nature-inspired and artificial intelligence–aided additive manufactured processes for different materials including biomanufacturing, and their applications, as well as various methods to enhance the characteristics of the materials produced, the efficiency of the manufacturing process itself, as well as optimal ways to develop a product in minimum time. The book explores the advancements in additive manufacturing from prefabrication stage to final product, with real-time defect detection, control, and process efficiency improvement covered. This book will be a great resource for engineers, researchers, and academics involved in this revolutionary and unique field of manufacturing. - Discusses modeling of additive manufacturing processes by artificial intelligence - Looks at the optimization of designs, technologies, and material fabrication and the use of simulation in additive manufacturing - Includes case studies and real-world industrial problems and solutions