Spatially Fractionated Microbeam Flashhb

Spatially Fractionated Microbeam Flashhb PDF Author: Hualin Zhang
Publisher: IOP Publishing Limited
ISBN: 9780750340441
Category : Medical
Languages : en
Pages : 0

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Book Description
This textbook is a comprehensive review of the physics of heterogeneous radiation and is linked, through a multidisciplinary approach, to clinical applications and biological considerations of heterogenous radiation. Fundamental principles of Spatially Fractionated Radiation Therapy (SFRT), techniques and technologies, dosimetric properties of SFRT, planning methods, documentation, standardized reporting metrics and clinical practice recommendations are comprehensively reviewed. The current status and results of clinical patient studies are presented, which have the potential to advance the management of bulky and advanced tumors. Potential biological underpinnings are reviewed that may challenge the current radiobiological understanding of radiation response and radiation therapy design parameters. Such multidisciplinary understanding is a critical foundation as the field of heterogeneous radiation rapidly advances in technological development and clinical investigation. **Key Features: ** GRID collimator- and MLC-based GRID therapy 3D Lattice radiation therapy Flash radiation therapy Minibeam and microbeam therapy Proton beam GRID therapy GRID and Lattice therapy plan evaluation and documentation Clinical applications of SFRT and patient outcomes Monte Carlo simulation techniques of SFRT Practical applications and procedures (where appropriate) Biological correlations and potential biological underpinnings Immune phenomena in SFRT

Spatially Fractionated Microbeam Flashhb

Spatially Fractionated Microbeam Flashhb PDF Author: Hualin Zhang
Publisher: IOP Publishing Limited
ISBN: 9780750340441
Category : Medical
Languages : en
Pages : 0

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Book Description
This textbook is a comprehensive review of the physics of heterogeneous radiation and is linked, through a multidisciplinary approach, to clinical applications and biological considerations of heterogenous radiation. Fundamental principles of Spatially Fractionated Radiation Therapy (SFRT), techniques and technologies, dosimetric properties of SFRT, planning methods, documentation, standardized reporting metrics and clinical practice recommendations are comprehensively reviewed. The current status and results of clinical patient studies are presented, which have the potential to advance the management of bulky and advanced tumors. Potential biological underpinnings are reviewed that may challenge the current radiobiological understanding of radiation response and radiation therapy design parameters. Such multidisciplinary understanding is a critical foundation as the field of heterogeneous radiation rapidly advances in technological development and clinical investigation. **Key Features: ** GRID collimator- and MLC-based GRID therapy 3D Lattice radiation therapy Flash radiation therapy Minibeam and microbeam therapy Proton beam GRID therapy GRID and Lattice therapy plan evaluation and documentation Clinical applications of SFRT and patient outcomes Monte Carlo simulation techniques of SFRT Practical applications and procedures (where appropriate) Biological correlations and potential biological underpinnings Immune phenomena in SFRT

Spatially Fractionated, Microbeam and FLASH Radiation Therapy

Spatially Fractionated, Microbeam and FLASH Radiation Therapy PDF Author: Hualin Zhang (Medical physicist)
Publisher:
ISBN: 9780750340465
Category : MEDICAL
Languages : en
Pages : 0

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Book Description
This textbook is a comprehensive review of the physics of heterogeneous radiation and is linked, through a multidisciplinary approach, to clinical applications and biological considerations of heterogenous radiation. Fundamental principles of Spatially Fractionated Radiation Therapy (SFRT), techniques and technologies, dosimetric properties of SFRT, planning methods, documentation, standardized reporting metrics and clinical practice recommendations are comprehensively reviewed. The current status and results of clinical patient studies are presented, which have the potential to advance the management of bulky and advanced tumors. Potential biological underpinnings are reviewed that may challenge the current radiobiological understanding of radiation response and radiation therapy design parameters. Such multidisciplinary understanding is a critical foundation as the field of heterogeneous radiation rapidly advances in technological development and clinical investigation. Part of IPEM-IOP Series in Physics and Engineering in Medicine and Biology.

Advances in Biological Understanding of Tumor Radiation Resistance

Advances in Biological Understanding of Tumor Radiation Resistance PDF Author: Ira Ida Skvortsova
Publisher: Frontiers Media SA
ISBN: 2889660532
Category : Medical
Languages : en
Pages : 235

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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Applied Nuclear Physics at Accelerators

Applied Nuclear Physics at Accelerators PDF Author: Marco Durante
Publisher: Frontiers Media SA
ISBN: 2889710394
Category : Medical
Languages : en
Pages : 728

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Book Description


Multidisciplinary Approaches to The FLASH Radiotherapy

Multidisciplinary Approaches to The FLASH Radiotherapy PDF Author: Fabio Di Martino
Publisher: Frontiers Media SA
ISBN: 2832550940
Category : Science
Languages : en
Pages : 140

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Book Description
Radiotherapy (RT) is a cornerstone of cancer treatment, being routinely used for approximately half of cancer patients in high-income countries. Despite the extensive use of RT for over 60 years, its toxicity on normal tissues often limits the treatment of radioresistant tumors and is responsible for significant decrease in patient’s quality of life. However, it was recently established that ultra-high dose rate (UHDR) irradiation induces significantly less normal tissues toxicities, while keeping similar antitumor effect compared to conventional dose rate irradiation. This so called “FLASH Effect" was demonstrated in vivo on different animal models and different organs by delivering the total amount of radiation dose in a very short time ( usually <200 ms), with average dose rates above 40 Gy/s and with different particles including electrons, protons and photons.

Pulse Radiolysis of Irradiated Systems

Pulse Radiolysis of Irradiated Systems PDF Author: Yoneho Tabata
Publisher: CRC Press
ISBN: 9780849348815
Category : Science
Languages : en
Pages : 520

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Book Description
Pulse Radiolysis presents an in-depth discussion of the pulse radiolysis technique, one of the most important and powerful means for detecting transient and relaxation phenomena and following their behavior in irradiated systems. The book covers the principle of pulse radiolysis, identifies various kinds of pulse radiolysis techniques, and discusses recent advancements in the field. The text also discusses new experimental pulse radiolysis techniques (basic and applied) in broad scientific fields such as physics, chemistry, biology, and engineering. These techniques include picosecond pulse radiolysis, single particle radiolysis, and muon-induced transient phenomena. Pulse Radiolysis provides essential information for all professionals involved with pulse radiolysis research.

Foundations of Medical Physics

Foundations of Medical Physics PDF Author: Victor J. Montemayor
Publisher: CRC Press
ISBN: 1040029019
Category : Medical
Languages : en
Pages : 631

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Book Description
Covering topics in Radiobiology, Modern Physics, Medical Imaging and Radiation Therapy, Foundations of Medical Physics serves as an introduction to the field of Medical Physics, or Radiation Oncology Physics. An overview of the history of cancer and cancer treatment along with a brief introduction to the fundamental principles of Radiobiology constitute Part I of this book, which serves as the motivation for the principles of Radiation Therapy, or cancer treatment with radiation. Part II contains the fundamental ideas from Modern Physics that form the foundation for an understanding of the approaches to treatment used in Radiation Therapy. Finally, Part III shows the applications of Parts I and II to Medical Imaging and Radiation Therapy. This unusual introduction to Medical Physics is aimed at undergraduate physics majors along with other science majors who have taken at least one year of Physics and one year of calculus, although Medical Physics graduate students and radiation oncology residents may find this different approach to the subject illuminating. This text assumes that the instructor is a physicist who does not necessarily have a background in Medical Physics.

Ionizing Radiation and the Immune Response - Part A

Ionizing Radiation and the Immune Response - Part A PDF Author:
Publisher: Elsevier
ISBN: 032395524X
Category : Science
Languages : en
Pages : 186

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Book Description
Ionizing Radiation and the Immune Response, Volume 376, Part A reviews the latest updates on the immune response induced by ionizing radiations. Sections discuss NK functions in radio-induced immune response, TRT and immune response, Radio-induced immune response and lipid metabolism, Effect of protons and heavy ions on immune response, Effect of flashtherapy and mini beam on immune response, Radio-induced lymphopenia, CT to potentiate radio-induced immune response, Impact of RT on healthy tissues (inflammation), Radio-induced macrophagic response, To use nanoparticles and ionizing radiations to modulate immune response: opinion of the chemist, biologist and clinician, and more. Additional sections touch on the Effect of low dose radiation on radio-induced immune response, Role of Dendritic cells in radiation-induced immune response, Relationship between the tumor microenvironment and the efficacy of the radiotherapy/immunotherapy combination+A23, and Biomarkers of radiation induced response to optimize radio-immunotherapy combination. Covers the latest insights on the biological and physical parameters that modulate radio-induced immune response Provides an accurate review by selected experts of the impact on the immune response of new techniques delivering ionizing radiations Presents valuable information to clinicians to optimize radiotherapy and immunotherapy combinations

Metal-Polymer Systems

Metal-Polymer Systems PDF Author: Jörg Florian Friedrich
Publisher: John Wiley & Sons
ISBN: 352733677X
Category : Technology & Engineering
Languages : en
Pages : 444

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Book Description
The result of decades of research by a pioneer in the field, this is the first book to deal exclusively with achieving high-performance metal-polymer composites by chemical bonding. Covering both the academic and practical aspects, the author focuses on the chemistry of interfaces between metals and polymers with a particular emphasis on the chemical bonding between the different materials. He elucidates the various approaches to obtaining a stable interface, including, but not limited to, thermodynamically driven redox reactions, bond protection to prevent hydrolysis, the introduction of barrier layers, and stabilization by spacer molecules. Throughout, chemical bonding is promoted as a simple and economically viable alternative to adhesion based on reversible weak physical interaction. Consequently, the text equips readers with the practical tools necessary for designing high-strength metal-polymer composites with such desired properties as resilience, flexibility, rigidity or degradation resistance.

Classical Relativistic Electrodynamics

Classical Relativistic Electrodynamics PDF Author: Toshiyuki Shiozawa
Publisher: Springer Science & Business Media
ISBN: 3662062615
Category : Science
Languages : en
Pages : 238

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Book Description
An advanced course of classical electrodynamics with application to the generation of high-power coherent radiation in the microwave to optical-wave regions. Specifically, it provides readers with the basics of advanced electromagnetic theory and relativistic electrodynamics, guiding them step by step through the theory of free-electron lasers. The theoretical treatment throughout this book is fully developed by means of the usual three-dimensional vector calculus.