Author: Nnadozie C. Oraguzie
Publisher: Springer Science & Business Media
ISBN: 0387360115
Category : Science
Languages : en
Pages : 290
Book Description
This book provides both basic and advanced understanding of association mapping and an awareness of population genomics tools to facilitate mapping and identification of the underlying causes of quantitative trait variation in plants. It acts as a useful review of the marker technology, the statistical methodology, and the progress to date. It also offers guides to the use of single nucleotide polymorphisms (SNPs) in association studies.
Association Mapping in Plants
Author: Nnadozie C. Oraguzie
Publisher: Springer Science & Business Media
ISBN: 0387360115
Category : Science
Languages : en
Pages : 290
Book Description
This book provides both basic and advanced understanding of association mapping and an awareness of population genomics tools to facilitate mapping and identification of the underlying causes of quantitative trait variation in plants. It acts as a useful review of the marker technology, the statistical methodology, and the progress to date. It also offers guides to the use of single nucleotide polymorphisms (SNPs) in association studies.
Publisher: Springer Science & Business Media
ISBN: 0387360115
Category : Science
Languages : en
Pages : 290
Book Description
This book provides both basic and advanced understanding of association mapping and an awareness of population genomics tools to facilitate mapping and identification of the underlying causes of quantitative trait variation in plants. It acts as a useful review of the marker technology, the statistical methodology, and the progress to date. It also offers guides to the use of single nucleotide polymorphisms (SNPs) in association studies.
Single Nucleotide Polymorphisms
Author: Anton A. Komar
Publisher: Humana Press
ISBN: 9781617796791
Category : Medical
Languages : en
Pages : 464
Book Description
In recent years, single nucleotide polymorphisms have received increased and special attention in a rapidly developing field of personalized medicine and drug treatment. Comprising more than eighty percent of all known polymorphisms, single nucleotide polymorphisms (SNPs) are primarily responsible for phenotypic differences between individuals, and have been suggested to affect the development of diseases in humans and the response to drug treatment and environmental stress. In Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition, expert researchers explore the latest advances in this area, highlighting the substantial progress that has been made in SNP genotyping, examining recent developments in high-throughput genotyping approaches, and exploring our new understanding of the impact of SNPs on gene function. Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Current and innovative, Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition is an essential guidebook for individual researchers as well as institutions and companies working in the field.
Publisher: Humana Press
ISBN: 9781617796791
Category : Medical
Languages : en
Pages : 464
Book Description
In recent years, single nucleotide polymorphisms have received increased and special attention in a rapidly developing field of personalized medicine and drug treatment. Comprising more than eighty percent of all known polymorphisms, single nucleotide polymorphisms (SNPs) are primarily responsible for phenotypic differences between individuals, and have been suggested to affect the development of diseases in humans and the response to drug treatment and environmental stress. In Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition, expert researchers explore the latest advances in this area, highlighting the substantial progress that has been made in SNP genotyping, examining recent developments in high-throughput genotyping approaches, and exploring our new understanding of the impact of SNPs on gene function. Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Current and innovative, Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition is an essential guidebook for individual researchers as well as institutions and companies working in the field.
Single Nucleotide Polymorphisms
Author: Pui-Yan Kwok
Publisher: Springer Science & Business Media
ISBN: 1592593275
Category : Medical
Languages : en
Pages : 276
Book Description
A comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection.
Publisher: Springer Science & Business Media
ISBN: 1592593275
Category : Medical
Languages : en
Pages : 276
Book Description
A comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection.
SNP
Author: Peter A. Lynch
Publisher:
ISBN: 9781860570575
Category : Nationalism
Languages : en
Pages : 0
Book Description
Though the SNP has existed since 1934, no full-length history of the Scottish National Party was written until the first edition of this book in 2002. With the SNP having governed Scotland since 2007, and with an outright majority since 2011, the long-held SNP policy of an Independence Referendum is now a reality and scheduled to be held in 2014.
Publisher:
ISBN: 9781860570575
Category : Nationalism
Languages : en
Pages : 0
Book Description
Though the SNP has existed since 1934, no full-length history of the Scottish National Party was written until the first edition of this book in 2002. With the SNP having governed Scotland since 2007, and with an outright majority since 2011, the long-held SNP policy of an Independence Referendum is now a reality and scheduled to be held in 2014.
Plant Genotyping II
Author: Robert J. Henry
Publisher: CABI
ISBN: 1845933834
Category : Science
Languages : en
Pages : 297
Book Description
Describes some of the developments in the field of Plant Genotyping, focusing on single nucleotide polymorphism (SNPs). This book covers the discovery, analysis and uses of SNPs, and examines other approaches to plant genotyping.
Publisher: CABI
ISBN: 1845933834
Category : Science
Languages : en
Pages : 297
Book Description
Describes some of the developments in the field of Plant Genotyping, focusing on single nucleotide polymorphism (SNPs). This book covers the discovery, analysis and uses of SNPs, and examines other approaches to plant genotyping.
Scottish National Party (SNP) Leaders
Author: James Mitchell
Publisher: Biteback Publishing
ISBN: 1785901230
Category : Political Science
Languages : en
Pages : 324
Book Description
By any measure, the story of the Scottish National Party is an extraordinary one. Forced to endure decades of electoral irrelevance since its creation in the 1930s, during which it often found itself grappling with internal debate on strategy, and rebellion from within its own ranks, the SNP virtually swept the board in the 2015 general election, winning all but three of Scotland's fifty-nine seats in Westminster. What's more, under the current leadership of Nicola Sturgeon, the SNP has never been a more important force in the landscape of British politics. The leaders who have stood at its helm during this tumultuous eighty-year history - from Sir Alexander MacEwen to Nicola Sturgeon and Alex Salmond - have steered the SNP vessel with varying degrees of success, but there is no doubt that all have contributed to the shape, purpose and ultimate goal of the party of government we see today. The latest addition to the acclaimed British Political Leaders series, Scottish National Party Leaders examines each of these senior figures for the first time, and is essential reading for anyone curious about how this former fringe party evolved into a political phenomenon, changing not only the face of Scottish politics, but British politics as well.
Publisher: Biteback Publishing
ISBN: 1785901230
Category : Political Science
Languages : en
Pages : 324
Book Description
By any measure, the story of the Scottish National Party is an extraordinary one. Forced to endure decades of electoral irrelevance since its creation in the 1930s, during which it often found itself grappling with internal debate on strategy, and rebellion from within its own ranks, the SNP virtually swept the board in the 2015 general election, winning all but three of Scotland's fifty-nine seats in Westminster. What's more, under the current leadership of Nicola Sturgeon, the SNP has never been a more important force in the landscape of British politics. The leaders who have stood at its helm during this tumultuous eighty-year history - from Sir Alexander MacEwen to Nicola Sturgeon and Alex Salmond - have steered the SNP vessel with varying degrees of success, but there is no doubt that all have contributed to the shape, purpose and ultimate goal of the party of government we see today. The latest addition to the acclaimed British Political Leaders series, Scottish National Party Leaders examines each of these senior figures for the first time, and is essential reading for anyone curious about how this former fringe party evolved into a political phenomenon, changing not only the face of Scottish politics, but British politics as well.
Advanced Topics in Forensic DNA Typing: Interpretation
Author: John M. Butler
Publisher: Academic Press
ISBN: 012405854X
Category : Social Science
Languages : en
Pages : 609
Book Description
Advanced Topics in Forensic DNA Typing: Interpretation builds upon the previous two editions of John Butler's internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. Intended as a third-edition companion to the Fundamentals of Forensic DNA Typing volume published in 2010 and Advanced Topics in Forensic DNA Typing: Methodology published in 2012, this book contains 16 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field. Over 80 % of the content of this book is new compared to previous editions. - Provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidence - Worked mixture examples illustrate the impact of different statistical approaches for reporting results - Includes allele frequencies for 24 commonly used autosomal STR loci, the revised Quality Assurance Standards which went into effect September 2011
Publisher: Academic Press
ISBN: 012405854X
Category : Social Science
Languages : en
Pages : 609
Book Description
Advanced Topics in Forensic DNA Typing: Interpretation builds upon the previous two editions of John Butler's internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. Intended as a third-edition companion to the Fundamentals of Forensic DNA Typing volume published in 2010 and Advanced Topics in Forensic DNA Typing: Methodology published in 2012, this book contains 16 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field. Over 80 % of the content of this book is new compared to previous editions. - Provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidence - Worked mixture examples illustrate the impact of different statistical approaches for reporting results - Includes allele frequencies for 24 commonly used autosomal STR loci, the revised Quality Assurance Standards which went into effect September 2011
Microarray Technology and Cancer Gene Profiling
Author: Simone Mocellin
Publisher: Springer Science & Business Media
ISBN: 038739978X
Category : Medical
Languages : en
Pages : 176
Book Description
Given the revolutionary implications that the use of this technology might have in the clinical management of cancer patients, the principles of DNA array-based tumor gene profiling must be clearly understood for the data to be correctly interpreted and appreciated. This book, written by leading experts, discusses the technical features characterizing the powerful laboratory tool of microarray technology, and reviews applications in the field of oncology.
Publisher: Springer Science & Business Media
ISBN: 038739978X
Category : Medical
Languages : en
Pages : 176
Book Description
Given the revolutionary implications that the use of this technology might have in the clinical management of cancer patients, the principles of DNA array-based tumor gene profiling must be clearly understood for the data to be correctly interpreted and appreciated. This book, written by leading experts, discusses the technical features characterizing the powerful laboratory tool of microarray technology, and reviews applications in the field of oncology.
Takeover
Author: Robert Johns
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
A Mexican Family Empire
Author: Charles H. Harris
Publisher: University of Texas Press
ISBN: 0292762593
Category : History
Languages : en
Pages : 433
Book Description
Perhaps no other institution has had a more significant impact on Latin American history than the large landed estate—the hacienda. In Mexico, the latifundio, an estate usually composed of two or more haciendas, dominated the social and economic structure of the country for four hundred years. A Mexican Family Empire is a careful examination of the largest latifundio ever to have existed, not only in Mexico but also in all of Latin America—the latifundio of the Sánchez Navarros. Located in the northern state of Coahuila, the Sánchez Navarro family's latifundio was composed of seventeen haciendas and covered more than 16.5 million acres—the size of West Virginia. Charles H. Harris places the history of the latifundio in perspective by showing the interaction between the various activities of the Sánchez Navarros and the evolution of landholding itself. In his discussion of the acquisition of land, the technology of ranching, labor problems, and production on the Sánchez Navarro estate, and of the family's involvement in commerce and politics, Harris finds that the development of the latifundio was only one aspect in the Sánchez Navarros' rise to power. Although the Sánchez Navarros conformed in some respects to the stereotypes advanced about hacendados, in terms of landownership and the use of debt peonage, in many important areas a different picture emerges. For example, the family's salient characteristic was a business mentality; they built the latifundio to make money, with status only a secondary consideration. Moreover, the family's extensive commercial activities belie the generalization that the objective of every hacendado was to make the estates self-sufficient. Harris emphasizes the great importance of the Sánchez Navarros' widespread network of family connections in their commercial and political activities. A Mexican Family Empire is based on the Sánchez Navarro papers—75,000 pages of personal letters, business correspondence, hacienda reports and inventories, wills, land titles, and court records spanning the period from 1658 to 1895. Harris's thorough research of these documents has resulted in the first complete social, economic, and political history of a great estate. The geographical and chronological boundaries of his study permit analysis of both continuity and change in Mexico's evolving socioeconomic structure during one of the most decisive periods in its history—the era of transition from colony to nation.
Publisher: University of Texas Press
ISBN: 0292762593
Category : History
Languages : en
Pages : 433
Book Description
Perhaps no other institution has had a more significant impact on Latin American history than the large landed estate—the hacienda. In Mexico, the latifundio, an estate usually composed of two or more haciendas, dominated the social and economic structure of the country for four hundred years. A Mexican Family Empire is a careful examination of the largest latifundio ever to have existed, not only in Mexico but also in all of Latin America—the latifundio of the Sánchez Navarros. Located in the northern state of Coahuila, the Sánchez Navarro family's latifundio was composed of seventeen haciendas and covered more than 16.5 million acres—the size of West Virginia. Charles H. Harris places the history of the latifundio in perspective by showing the interaction between the various activities of the Sánchez Navarros and the evolution of landholding itself. In his discussion of the acquisition of land, the technology of ranching, labor problems, and production on the Sánchez Navarro estate, and of the family's involvement in commerce and politics, Harris finds that the development of the latifundio was only one aspect in the Sánchez Navarros' rise to power. Although the Sánchez Navarros conformed in some respects to the stereotypes advanced about hacendados, in terms of landownership and the use of debt peonage, in many important areas a different picture emerges. For example, the family's salient characteristic was a business mentality; they built the latifundio to make money, with status only a secondary consideration. Moreover, the family's extensive commercial activities belie the generalization that the objective of every hacendado was to make the estates self-sufficient. Harris emphasizes the great importance of the Sánchez Navarros' widespread network of family connections in their commercial and political activities. A Mexican Family Empire is based on the Sánchez Navarro papers—75,000 pages of personal letters, business correspondence, hacienda reports and inventories, wills, land titles, and court records spanning the period from 1658 to 1895. Harris's thorough research of these documents has resulted in the first complete social, economic, and political history of a great estate. The geographical and chronological boundaries of his study permit analysis of both continuity and change in Mexico's evolving socioeconomic structure during one of the most decisive periods in its history—the era of transition from colony to nation.