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Author: S. Sideman
Publisher: Springer Science & Business Media
ISBN: 9400949928
Category : Medical
Languages : en
Pages : 448
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Book Description
The ultrasound velocity tomography allows measurement of cardiac geometries for various phases in the cardiac cycle. The present tomograph makes reconstruc tions at intervals of 20 ms. Because of a lack of clear (intramural) landmarks (except the roots of the papillairy muscle), it is difficult to pinpoint spatial trajectories of particular points in the heart. Therefore, a second method was developed of injecting radiopaque markers in the heart and following their motion patterns during the cardiac cycle with help of a biplane X-ray equipment. The data obtained with both methods can be implemented in our finite element model of the heart to compute intramural stresses and strains. The results obtained sofar with the extended Darcy equation to account for the interaction of blood rheology and tissue mechanics look promising. Further testing with more sophisticated subjects than mentioned in Figure 9 is required before it will be implemented in our finite element model of the heart. We conclude that analysis of regional cardiac function, including regional myocardial blood flow, requires still a major research effort but the results obtained sofar justify, to our opinion, a continuation in this direction. Acknowledgement The authors acknowledge Dr. C. Borst and coworkers for doing the animal experiments and prof. Van Campen and dr. Grootenboer for their participation is some aspects of this work.
Author: S. Sideman
Publisher: Springer Science & Business Media
ISBN: 9400949928
Category : Medical
Languages : en
Pages : 448
Get Book Here
Book Description
The ultrasound velocity tomography allows measurement of cardiac geometries for various phases in the cardiac cycle. The present tomograph makes reconstruc tions at intervals of 20 ms. Because of a lack of clear (intramural) landmarks (except the roots of the papillairy muscle), it is difficult to pinpoint spatial trajectories of particular points in the heart. Therefore, a second method was developed of injecting radiopaque markers in the heart and following their motion patterns during the cardiac cycle with help of a biplane X-ray equipment. The data obtained with both methods can be implemented in our finite element model of the heart to compute intramural stresses and strains. The results obtained sofar with the extended Darcy equation to account for the interaction of blood rheology and tissue mechanics look promising. Further testing with more sophisticated subjects than mentioned in Figure 9 is required before it will be implemented in our finite element model of the heart. We conclude that analysis of regional cardiac function, including regional myocardial blood flow, requires still a major research effort but the results obtained sofar justify, to our opinion, a continuation in this direction. Acknowledgement The authors acknowledge Dr. C. Borst and coworkers for doing the animal experiments and prof. Van Campen and dr. Grootenboer for their participation is some aspects of this work.
Author: S. Sideman
Publisher:
ISBN: 9789400949935
Category :
Languages : en
Pages : 452
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Book Description
Author: Samuel Sideman
Publisher:
ISBN: 9789652940759
Category : Heart
Languages : en
Pages : 801
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Book Description
Author: Roy C.P. Kerckhoffs
Publisher: Springer Science & Business Media
ISBN: 1441966919
Category : Science
Languages : en
Pages : 253
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Book Description
Peter Hunter Computational physiology for the cardiovascular system is entering a new and exciting phase of clinical application. Biophysically based models of the human heart and circulation, based on patient-specific anatomy but also informed by po- lation atlases and incorporating a great deal of mechanistic understanding at the cell, tissue, and organ levels, offer the prospect of evidence-based diagnosis and treatment of cardiovascular disease. The clinical value of patient-specific modeling is well illustrated in application areas where model-based interpretation of clinical images allows a more precise analysis of disease processes than can otherwise be achieved. For example, Chap. 6 in this volume, by Speelman et al. , deals with the very difficult problem of trying to predict whether and when an abdominal aortic aneurysm might burst. This requires automated segmentation of the vascular geometry from magnetic re- nance images and finite element analysis of wall stress using large deformation elasticity theory applied to the geometric model created from the segmentation. The time-varying normal and shear stress acting on the arterial wall is estimated from the arterial pressure and flow distributions. Thrombus formation is identified as a potentially important contributor to changed material properties of the arterial wall. Understanding how the wall adapts and remodels its material properties in the face of changes in both the stress loading and blood constituents associated with infl- matory processes (IL6, CRP, MMPs, etc.
Author: Luca Formaggia
Publisher: Springer Science & Business Media
ISBN: 8847011523
Category : Mathematics
Languages : en
Pages : 528
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Book Description
Mathematical models and numerical simulations can aid the understanding of physiological and pathological processes. This book offers a mathematically sound and up-to-date foundation to the training of researchers and serves as a useful reference for the development of mathematical models and numerical simulation codes.
Author: Frank B. Sachse
Publisher: Springer
ISBN: 3540729070
Category : Computers
Languages : en
Pages : 498
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Book Description
This book constitutes the refereed proceedings of the 4th International Conference on Functional Imaging and Modeling of the Heart, FIMH 2007, held in Salt Lake City, UT, USA in June 2007. The contributions describe both experimental and computational studies and cover topics such as imaging and image analysis, cardiac electrophysiology, electro- and magnetocardiography, cardiac mechanics and clinical application, imaging and anatomical modeling.
Author: Luca Formaggia
Publisher: Springer
ISBN: 9788847011571
Category : Mathematics
Languages : en
Pages : 526
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Book Description
Mathematical models and numerical simulations can aid the understanding of physiological and pathological processes. This book offers a mathematically sound and up-to-date foundation to the training of researchers and serves as a useful reference for the development of mathematical models and numerical simulation codes.
Author: Krishnan B. Chandran
Publisher: Springer Science & Business Media
ISBN: 1441973508
Category : Technology & Engineering
Languages : en
Pages : 474
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Book Description
Image-Based Computational Modeling of the Human Circulatory and Pulmonary Systems provides an overview of the current modeling methods and applications enhancing interventional treatments and computer-aided surgery. A detailed description of the techniques behind image acquisition, processing and three-dimensional reconstruction are included. Techniques for the computational simulation of solid and fluid mechanics and structure interaction are also discussed, in addition to various cardiovascular and pulmonary applications. Engineers and researchers involved with image processing and computational modeling of human organ systems will find this a valuable reference.
Author: Isabelle E. Magnin
Publisher: Springer
ISBN: 3540448837
Category : Medical
Languages : en
Pages : 319
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Book Description
The refereed proceedings of the Second International Workshop on Functional Imaging and Modeling of the Heart, FIMH 2003, held in Lyon, France in June 2003. The 29 revised full papers presented together with 2 invited papers were carefully reviewed and selected for presentation. The papers are organized in topical sections on anatomy extraction and description, modeling of the cardiac mechanics and functions, electro-physiology and electro- and magnetography, motion estimation, image registration and image analysis, and data acquisition and experimental and modeling issues.
Author: Dimitris N. Metaxas
Publisher: Springer Science & Business Media
ISBN: 3642210279
Category : Computers
Languages : en
Pages : 452
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Book Description
This book constitutes the proceedings of the 6th International Conference on Functional Imaging and Modeling of the Heart, held in New York City, NY, USA in May 2011. The 24 revised full papers presented together with 29 revised poster papers were carefully reviewed and selected from about 120 initial submissions. The contributions feature current research and development efforts in the fields of cardiovascular modeling, physiology, and image-based analysis, at a range of scales and imaging methods. Topics addresses are such as imaging, signal and image processing, applied mathematics, biomedical engineering and computer science; biologically oriented fields such as cardiac physiology and biology; as well as clinical issues such as cardiology, radiology and surgery, with a common interest in the heart.
