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Author: Lewis C. Cantley
Publisher:
ISBN: 9780879699017
Category : Science
Languages : en
Pages : 452
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Book Description
"This textbook provides a comprehensive view of signal transduction, covering both the fundamental mechanisms involved and their roles in key biological processes. It first lays out the basic principles of signal transduction, explaining how different receptors receive information and transmit it via signaling proteins, ions, and second messengers. It then surveys the major signaling pathways that operate in cells, before examining in detail how these function in processes such as cell growth and division, cell movement, metabolism, development, reproduction, the nervous system, and immune function"--
Author: Lewis C. Cantley
Publisher:
ISBN: 9780879699017
Category : Science
Languages : en
Pages : 452
Get Book Here
Book Description
"This textbook provides a comprehensive view of signal transduction, covering both the fundamental mechanisms involved and their roles in key biological processes. It first lays out the basic principles of signal transduction, explaining how different receptors receive information and transmit it via signaling proteins, ions, and second messengers. It then surveys the major signaling pathways that operate in cells, before examining in detail how these function in processes such as cell growth and division, cell movement, metabolism, development, reproduction, the nervous system, and immune function"--
Author: Bastien D. Gomperts
Publisher: Gulf Professional Publishing
ISBN: 9780122896323
Category : Medical
Languages : en
Pages : 444
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Book Description
Signal Transduction is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particularly cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources, key observations and experiments that set the scene for recent and current work.
Author: Gerhard Krauss
Publisher: John Wiley & Sons
ISBN: 3527605762
Category : Science
Languages : de
Pages : 558
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Book Description
This all-new edition of a classic text has been thoroughly revised to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes. Directed to advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis. "Provides a comprehensive account of cell signaling and signal transduction and, where possible, explains these processes at the molecular level" (Angewandte Chemie) "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry) "This book is actually two books: Regulation and Signal Transduction." (Drug Research)
Author: Ari Sitaramayya
Publisher: Springer Science & Business Media
ISBN: 3642021123
Category : Science
Languages : en
Pages : 429
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Book Description
Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.
Author: Friedrich Marks
Publisher: Garland Science
ISBN: 1351677217
Category : Medical
Languages : en
Pages : 982
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Book Description
Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
Author: Salvatore V. Pizzo
Publisher: Academic Press
ISBN: 0128123524
Category : Science
Languages : en
Pages : 146
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Book Description
Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. - Edited by the researcher who identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies - Presents an in-depth treatment of the biological underpinnings of GRP78 and its connection to disease - Provides four-color illustrations that facilitate the narrative
Author: Ryutaro Utsumi
Publisher: Springer Science & Business Media
ISBN: 0387788859
Category : Medical
Languages : en
Pages : 257
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Book Description
This fascinating book encourages many microbiologists and students to enter the new world of signal transduction in microbiology. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been unearthed.
Author: Carl-Henrik Heldin
Publisher: Garland Science
ISBN: 9780748740741
Category : Science
Languages : en
Pages : 402
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Book Description
Signal Transduction was published in association with The International Union of Biochemistry and Molecular Biology. In a series of twenty-three short chapters, leading researchers provide cutting-edge reviews of signal transduction, and form cell membrane receptors through to gene regulation. Written for those with a basic understanding of molecular and cell biology, the book will be of particular interest to graduate students and researchers who need to grasp the principles of signal transduction.
Author: Danton H. O'Day
Publisher: Academic Press
ISBN: 0323141455
Category : Science
Languages : en
Pages : 285
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Book Description
Signal Transduction during Biomembrane Fusion begins with three review articles that put the problem of signal transduction and biomembrane fusion into a general perspective. Each subsequent chapter begins with an introduction which reviews past work on a specific biological system. The authors' current research is then detailed. The chapters conclude with final comments wherein the contributors express viewpoints about the general significance and progression of their work. This book comprises 12 chapters, with the first focusing on signal transduction during biomembrane fusion. The succeeding chapters then discuss the ""focal membrane fusion"" model; osmotic phenomena in membrane fusion; cell signaling and regulation of exocytosis at fertilization of the egg; and signal transduction during exocytosis in mast cells. Other chapters cover protein kinase c and granule membrane fusion; GTP-binding proteins and formation of secretory vesicles; and signal transduction during phagocytosis. The remaining chapters discuss calcium signal transduction pathway and myoblast fusion; phospholipid metabolism during calcium-regulated myoblast fusion; protein kinase c, membrane protein phosphorylation, and calcium influx in chick embryo skeletal myoblast fusion; and signal transduction and cell fusion in dictyostelium. This book will be of interest to practitioners in the fields of neurobiology, zoology, and the biological sciences.
Author: Linda J. Van Eldik
Publisher: Academic Press
ISBN: 0080926363
Category : Science
Languages : en
Pages : 497
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Book Description
Calmodulin and Signal Transduction focuses on emerging themes in the molecular mechanisms of calcium signal transduction through calmodulin-regulated pathways. It provides the reader with selected examples and experimental precedents that underlie current models of cell regulation through calmodulin-regulated pathways and their linkage with other regulatory pathways. - Molecular mechanisms of calcium signal transduction through calmodulin-regulated enzymes - Selected case studies and precedents related to molecular mechanisms - Protein-protein recognition between calmodulin and the enzymes it regulates - Cross-talk and interdigitation with other signal transduction pathways
