Short Pulse Laser Systems for Biomedical Applications

Short Pulse Laser Systems for Biomedical Applications PDF Author: Kunal Mitra
Publisher: Springer
ISBN: 3319542532
Category : Technology & Engineering
Languages : en
Pages : 53

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Book Description
This book presents practical information on the clinical applications of short pulse laser systems and the techniques for optimizing these applications in a manner that will be relevant to a broad audience, including engineering and medical students as well as researchers, clinicians, and technicians. Short pulse laser systems are useful for both subsurface tissue imaging and laser induced thermal therapy (LITT), which hold great promise in cancer diagnostics and treatment. Such laser systems may be used alone or in combination with optically active nanoparticles specifically administered to the tissues of interest for enhanced contrast in imaging and precise heating during LITT. Mathematical and computational models of short pulse laser-tissue interactions that consider the transient radiative transport equation coupled with a bio-heat equation considering the initial transients of laser heating were developed to analyze the laser-tissue interaction during imaging and therapy. Experiments were first performed to characterize the tissue optical properties needed to optimize the dose for thermal therapy. Experiments were then performed on animal models to characterize the heat affected zone for LITT. The experimental measurements were also validated using the computational models.

Short Pulse Laser Systems for Biomedical Applications

Short Pulse Laser Systems for Biomedical Applications PDF Author: Kunal Mitra
Publisher: Springer
ISBN: 3319542532
Category : Technology & Engineering
Languages : en
Pages : 53

Get Book Here

Book Description
This book presents practical information on the clinical applications of short pulse laser systems and the techniques for optimizing these applications in a manner that will be relevant to a broad audience, including engineering and medical students as well as researchers, clinicians, and technicians. Short pulse laser systems are useful for both subsurface tissue imaging and laser induced thermal therapy (LITT), which hold great promise in cancer diagnostics and treatment. Such laser systems may be used alone or in combination with optically active nanoparticles specifically administered to the tissues of interest for enhanced contrast in imaging and precise heating during LITT. Mathematical and computational models of short pulse laser-tissue interactions that consider the transient radiative transport equation coupled with a bio-heat equation considering the initial transients of laser heating were developed to analyze the laser-tissue interaction during imaging and therapy. Experiments were first performed to characterize the tissue optical properties needed to optimize the dose for thermal therapy. Experiments were then performed on animal models to characterize the heat affected zone for LITT. The experimental measurements were also validated using the computational models.

Ultrashort Pulse Laser Technology

Ultrashort Pulse Laser Technology PDF Author: Stefan Nolte
Publisher: Springer
ISBN: 3319176595
Category : Science
Languages : en
Pages : 365

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Book Description
Ultrashort laser pulses with durations in the femtosecond range up to a few picoseconds provide a unique method for precise materials processing or medical applications. Paired with the recent developments in ultrashort pulse lasers, this technology is finding its way into various application fields. The book gives a comprehensive overview of the principles and applications of ultrashort pulse lasers, especially applied to medicine and production technology. Recent advances in laser technology are discussed in detail. This covers the development of reliable and cheap low power laser sources as well as high average power ultrashort pulse lasers for large scale manufacturing. The fundamentals of laser-matter-interaction as well as processing strategies and the required system technology are discussed for these laser sources with respect to precise materials processing. Finally, different applications within medicine, measurement technology or materials processing are highlighted.

Ultrashort Laser Pulse Phenomena

Ultrashort Laser Pulse Phenomena PDF Author: Jean-Claude Diels
Publisher: Elsevier
ISBN: 0080466400
Category : Science
Languages : en
Pages : 675

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Book Description
Ultrashort Laser Pulse Phenomena, Second Edition serves as an introduction to the phenomena of ultra short laser pulses and describes how this technology can be used to examine problems in areas such as electromagnetism, optics, and quantum mechanics. Ultrashort Laser Pulse Phenomena combines theoretical backgrounds and experimental techniques and will serve as a manual on designing and constructing femtosecond ("faster than electronics") systems or experiments from scratch. Beyond the simple optical system, the various sources of ultrashort pulses are presented, again with emphasis on the basic concepts and how they apply to the design of particular sources (dye lasers, solid state lasers, semiconductor lasers, fiber lasers, and sources based on frequency conversion). - Provides an easy to follow guide through "faster than electronics" probing and detection methods - THE manual on designing and constructing femtosecond systems and experiments - Discusses essential technology for applications in micro-machining, femtochemistry, and medical imaging

Lasers for Medical Applications

Lasers for Medical Applications PDF Author: Helena Jelínková
Publisher: Elsevier
ISBN: 0857097547
Category : Technology & Engineering
Languages : en
Pages : 827

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Book Description
Lasers have a wide and growing range of applications in medicine. Lasers for Medical Applications summarises the wealth of recent research on the principles, technologies and application of lasers in diagnostics, therapy and surgery.Part one gives an overview of the use of lasers in medicine, key principles of lasers and radiation interactions with tissue. To understand the wide diversity and therefore the large possible choice of these devices for a specific diagnosis or treatment, the respective types of the laser (solid state, gas, dye, and semiconductor) are reviewed in part two. Part three describes diagnostic laser methods, for example optical coherence tomography, spectroscopy, optical biopsy, and time-resolved fluorescence polarization spectroscopy. Those methods help doctors to refine the scope of involvement of the particular body part or, for example, to specify the extent of a tumor. Part four concentrates on the therapeutic applications of laser radiation in particular branches of medicine, including ophthalmology, dermatology, cardiology, urology, gynecology, otorhinolaryngology (ORL), neurology, dentistry, orthopaedic surgery and cancer therapy, as well as laser coatings of implants. The final chapter includes the safety precautions with which the staff working with laser instruments must be familiar.With its distinguished editor and international team of contributors, this important book summarizes international achievements in the field of laser applications in medicine in the past 50 years. It provides a valuable contribution to laser medicine by outstanding experts in medicine and engineering. - Describes the interaction of laser light with tissue - Reviews every type of laser used in medicine: solid state, gas, dye and semiconductor - Describes the use of lasers for diagnostics

Laser-Tissue Interactions

Laser-Tissue Interactions PDF Author: Markolf Niemz
Publisher: Springer Science & Business Media
ISBN: 3662031930
Category : Science
Languages : en
Pages : 303

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Book Description
Laser--Tissue Interactions provides a thorough description of the fundamentals and applications in this field. Basic conceptions such as optical and thermal properties of tissue, various types of tissue ablation, and optical breakdown with related effects are treated in detail. Special attention is given to mathematical tools (Monte Carlo simulations, Kubelka--Munk theory) and approved techniques (photodynamic therapy, laser-induced interstitial thermotherapy). The part on applications reviews clinically relevant methods in modern medicine according to the latest references. The last chapter includes today's standards of laser safety, with a careful selection of essential guidelines published

The Physics and Engineering of Compact Quantum Dot-based Lasers for Biophotonics

The Physics and Engineering of Compact Quantum Dot-based Lasers for Biophotonics PDF Author: Edik U. Rafailov
Publisher: John Wiley & Sons
ISBN: 3527665609
Category : Science
Languages : en
Pages : 349

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Book Description
Written by a team of European experts in the field, this book addresses the physics, the principles, the engineering methods, and the latest developments of efficient and compact ultrafast lasers based on novel quantum-dot structures and devices, as well as their applications in biophotonics. Recommended reading for physicists, engineers, students and lecturers in the fields of photonics, optics, laser physics, optoelectronics, and biophotonics.

Ultrafast Optics IV

Ultrafast Optics IV PDF Author: Ferenc Krausz
Publisher: Springer
ISBN: 0387347569
Category : Science
Languages : en
Pages : 482

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Book Description
The papers in this volume cover the major areas of research activity in the field of ultrafast optics at the present time, and they have been selected to provide an overview of the current state of the art. The purview of the field is the methods for the generation, amplification, and characterization of electromagnetic pulses with durations from the pieo-to the attosecond range, as well as the technical issues surrounding the application of these pulses in physics, chemistry, and biology. The contributions were solicited from the participants in the Ultrafast Optics IV Conference, held in Vienna, Austria, in June 2003. The purpose of the conference is similar to that of this book: to provide a forum for the latest advances in ultrafast optical technology. Ultrafast light sources provide a means to observe and manipulate events on the scale of atomic and molecular dynamics. This is possible either through appropriate shaping of the time-dependent electrie field, or through the ap plication of fields whose strength is comparable to the binding forces of the electrons in atoms and molecules. Recent advances discussed here include the generation of pulses shorter than two optical cycles, and the ability to measure and to shape them in all degrees of freedom with unprecedented 2 21 2 precision, and to amplify them to the Zettawatt/cm (10 W /cm ) range.

Laser Systems for Applications

Laser Systems for Applications PDF Author: Krzysztof Jakubczak
Publisher: BoD – Books on Demand
ISBN: 9533074299
Category : Science
Languages : en
Pages : 322

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Book Description
This book addresses topics related to various laser systems intended for the applications in science and various industries. Some of them are very recent achievements in laser physics (e.g. laser pulse cleaning), while others face their renaissance in industrial applications (e.g. CO2 lasers). This book has been divided into four different sections: (1) Laser and terahertz sources, (2) Laser beam manipulation, (3) Intense pulse propagation phenomena, and (4) Metrology. The book addresses such topics like: Q-switching, mode-locking, various laser systems, terahertz source driven by lasers, micro-lasers, fiber lasers, pulse and beam shaping techniques, pulse contrast metrology, and improvement techniques. This book is a great starting point for newcomers to laser physics.

Coherence and Ultrashort Pulse Laser Emission

Coherence and Ultrashort Pulse Laser Emission PDF Author: F. J. Duarte
Publisher: BoD – Books on Demand
ISBN: 9533072423
Category : Technology & Engineering
Languages : en
Pages : 702

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Book Description
In this volume, recent contributions on coherence provide a useful perspective on the diversity of various coherent sources of emission and coherent related phenomena of current interest. These papers provide a preamble for a larger collection of contributions on ultrashort pulse laser generation and ultrashort pulse laser phenomena. Papers on ultrashort pulse phenomena include works on few cycle pulses, high-power generation, propagation in various media, to various applications of current interest. Undoubtedly, Coherence and Ultrashort Pulse Emission offers a rich and practical perspective on this rapidly evolving field.

Medical Devices

Medical Devices PDF Author: Martin Culjat
Publisher: John Wiley & Sons
ISBN: 1118453530
Category : Science
Languages : en
Pages : 452

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Book Description
Addressing the exploding interest in bioengineering for healthcare applications, this book provides readers with detailed yet easy-to-understand guidance on biomedical device engineering. Written by prominent physicians and engineers, Medical Devices: Surgical and Image-Guided Technologies is organized into stand-alone chapters covering devices and systems in diagnostic, surgical, and implant procedures. Assuming only basic background in math and science, the authors clearly explain the fundamentals for different systems along with such topics as engineering considerations, therapeutic techniques and applications, future trends, and more. After describing how to manage a design project for medical devices, the book examines the following: Instruments for laparoscopic and ophthalmic surgery, plus surgical robotics Catheters in vascular therapy and energy-based hemostatic surgical devices Tissue ablation systems and the varied uses of lasers in medicine Vascular and cardiovascular devices, plus circulatory support devices Ultrasound transducers, X-ray imaging, and neuronavigation An absolute must for biomedical engineers, Medical Devices: Surgical and Image-Guided Technologies is also an invaluable guide for students in all engineering majors and pre-med programs interested in exploring this fascinating field.