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Languages : en
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Author: D. Leo Pyle
Publisher: Springer Science & Business Media
ISBN: 9400907834
Category : Science
Languages : en
Pages : 659
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The challenge of bioseparations is to isolate and purify identified products from the dilute product broth produced from cell culture. Innovation in bioseparations technology is increasingly driven by the requirements imposed by the growing importance of production on a process scale of injectable-grade products, and economic pressures to improve the efficiency of downstream processing. As in other areas of technical change, science does not necessarily precede new technology: progress results from a complex and messy mixture of advances in understanding, ingenious ideas, novel techniques and chance discoveries. What is certain is that close interaction between academics and practitioners, biological scientists and process engineers is needed to solve the problems of bioseparations. The Second International Conference on Separations for Biotechnology at Reading, UK, in September 1990 set out to provide a critical multidisciplinary forum for the discussion of bioseparations. This volume contains the papers presented at the meeting. The meeting was organised around six themes with oral and poster presentations on the science and practice of bioseparations technology, and the same structure has been kept for this book. We have also included the texts of the keynote review paper by Professor Alan Michaels and the introductory review papers specially commissioned for the conference. Within each part of this book the review paper is followed by the contributed papers grouped alphabetically by their first author. All the original papers published here were accepted for publication after scientific refereeing.
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Languages : en
Pages : 39
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Selected presentations given at this conference, held in September 1987, are reviewed. Topics are: cell harvesting and disruption, adsorption and chromatography, analytic techniques and process control, liquid-liquid extraction, and membrane extraction. Contents of this report include: Recovery of Cells from Fermentation Broths; Biochemical Engineering Aspects of Cell Disruption; Biosurface Properties--Primary Separation; Production of Dextran and Fructose; Modeling for Scale-up of Packed-Bed Column; Fractionation of Proteins; On-Line Monitoring; Biosensors in Downstream Processing. Keywords: Reactor separators; Dynamic partitioning.
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Languages : en
Pages : 114
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This is the detailed report and proceedings from The 7th International Conference on Partitioning in Aqueous Tw6-Phase Systems: Advances in Separation in Biochemistry Cell Biology and Biotechnology, June 2-7, 1991, New Orleans, Louisiana, U.S.A.
Author: D. Fisher
Publisher: Springer Science & Business Media
ISBN: 1468456679
Category : Science
Languages : en
Pages : 476
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The use of aqueous two-phase systems for the partitioning of macromolecules, organelles and cells was originally developed by Per-Ake Albertsson in Sweden in the mid-fifties [1-3]. These systems were initially applied to separations of plant organelles and viruses but their use has now extended into most areas of cell biology and biochemistry [4,5]. Since 1979 biennial International Conferences on Partitioning in Aqueous Two-Phase Systems have been held in Los Angeles (1979), Sheffield (1981), Vancouver (1983) and Lund (1985). The 5th conference was held in Oxford from 23-28 August 1987 and was entitled "Advances in Separations Using Aqueous Phase Systems in Cell Biology and Biotechnology". It is the formal presentations from this meeting which comprise this volume. In contrast to earlier books on phase partitioning [4,5] this volume contains, for the first time, worldwide contributions from over sixty partitioners from a variety of scientific disciplines, thereby providing a detailed overview of the widespread application and potential of bioseparations using phase partitioning. Disciplines include Biophysics, Biochemistry, Cell Biology, Microbiology, Biotechnology and Process Engineering, in both academic and commercial establishments. These biennial conferences allow advances in these diverse partitioning fields to be reviewed and compared; they also provide an opportunity for those considering using phase partitioning to obtain information, advice and contacts. Attendance has grown steadily over the years and 140 scientists came to Oxford. The conference consisted of ten symposia on areas of application of partitioning which have been organised as specific chapters in this volume.
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Languages : en
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Author: D. L. Pyle
Publisher:
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Category : Biomolecules
Languages : en
Pages : 111
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Author: EuroScicon
Publisher: EuroScicon
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 80
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July 05-07, 2018 Berlin, Germany Key Topics : Recent Developments In Separation Techniques, Recent Upgrades In Sample Preparation Process, Bio-Separation Techniques, Biomarker And Biosensors Analysis - Regulations, Separation Techniques In Biochemistry, Analytical Chemistry, Mass Spectrometry, Spectroscopic Methods In Separation Techniques, Emerging Industrial Separation Technologies, Hyphenated Techniques, Chromatography, Separation Techniques In Organic Chemistry., Separations In Inorganic Chemistry, Separation Techniques In Environmental Chemistry, Desalination & Wastewater Treatment Techniques, Separation Techniques In Chemical Engineering, Membrane Separation Techniques, Separation Techniques Used In Nanotechnology, Current Trends In Fundamental Separation Techniques, Separation Techniques In Clinical / Pharmaceutical Chemistry, New Instrumentation And Multidimensional Separations, Separation Techniques And Applications, Separation Techniques Used In Geology / Mineralogy, Market Analysis Of Separation Techniques, Fractionation & Magnetism As A Separation Technique, Separation Based On Rate Phenomena,
Author: Wallace Woon-Fong Leung
Publisher: Butterworth-Heinemann
ISBN: 0081026358
Category : Technology & Engineering
Languages : en
Pages : 503
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Centrifugal Separations in Biotechnology, Second Edition, is the only book on the market devoted to centrifugal separation in biotechnology. Key topics covered include a full introduction to centrifugation, sedimentation and separation; detailed coverage of centrifuge types, including batch and semi-batch centrifuges, disk-stack and tubular decanter centrifuges; methods for increasing solids concentration; laboratory and pilot testing of centrifuges; selection and sizing centrifuges; scale-up of equipment, performance prediction and analysis of test results using numerical simulation. Centrifugal Separations in Biotechnology, Second Edition, provides guidance on troubleshooting and optimizing centrifuges, and then goes on to explore the commercial applications of centrifuges in biotechnology. It gives detailed process information and data to assist in the development of particular processes from existing systems. It is of value to professionals in the chemical, bioprocess, and biotech sectors, and all those concerned with bioseparation, bioprocessing, unit-operations and process engineering. Provides a comprehensive guide to centrifuges, their optimal development, and their operation in the biotechnology industry Updated throughout based on developments in industrial applications and advances in our understanding of centrifugal separations in biotechnology Discusses applications for the separation of proteins, DNA, mitochondria, ribosomes, lysosomes and other cellular elements Includes new sections on use of optimal polymer dosage in waste treatment, new centrifuge designs for applications in algae processing, biopharma, and more
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Category :
Languages : en
Pages : 112
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