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Author: William D. Willis Jr.
Publisher: Springer Science & Business Media
ISBN: 1461500370
Category : Medical
Languages : en
Pages : 604
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Book Description
The third edition of this monograph continues to have the goal of providing an overview of current thought about the spinal cord mechanisms that are responsible for sensory processing. We hope that the book is of value to both basic and clinical neuroscientists. Several changes have been made in the presentation, as well as additions because of the research advances that have been made during the past decade. Chapters 3 and 4 in the previous edition have been subdivided, and now the morphology of primary afferent neu rons of the dorsal root ganglia is described in Chapter 3 and the chemical neuroanatomy 4. The description of the dorsal hom in the previous Chapter 4 of these neurons in Chapter is now included in Chapter 5, and the chemical neuroanatomy of the dorsal hom in Chapter 6. Furthermore, discussions of the descending control systems have now been of Chapter 12. consolidated at the end The authors would like to express their appreciation for the help provided by several individuals. R.E.C. wishes to acknowledge the many things he learned about primary afferent neurons from conversations with Dr S. N. Lawson. He also thanks Lyn Shilling for her assistance with the typing. WDW thanks Dr Nada Lawand for her critical reading of parts of the manuscript, Rosaline Leigh for help with the manuscript, and Griselda Gonzales for preparing the illustrations.
Author: William D. Willis Jr.
Publisher: Springer Science & Business Media
ISBN: 1461500370
Category : Medical
Languages : en
Pages : 604
Get Book Here
Book Description
The third edition of this monograph continues to have the goal of providing an overview of current thought about the spinal cord mechanisms that are responsible for sensory processing. We hope that the book is of value to both basic and clinical neuroscientists. Several changes have been made in the presentation, as well as additions because of the research advances that have been made during the past decade. Chapters 3 and 4 in the previous edition have been subdivided, and now the morphology of primary afferent neu rons of the dorsal root ganglia is described in Chapter 3 and the chemical neuroanatomy 4. The description of the dorsal hom in the previous Chapter 4 of these neurons in Chapter is now included in Chapter 5, and the chemical neuroanatomy of the dorsal hom in Chapter 6. Furthermore, discussions of the descending control systems have now been of Chapter 12. consolidated at the end The authors would like to express their appreciation for the help provided by several individuals. R.E.C. wishes to acknowledge the many things he learned about primary afferent neurons from conversations with Dr S. N. Lawson. He also thanks Lyn Shilling for her assistance with the typing. WDW thanks Dr Nada Lawand for her critical reading of parts of the manuscript, Rosaline Leigh for help with the manuscript, and Griselda Gonzales for preparing the illustrations.
Author: William D. Willis
Publisher: Springer Science & Business Media
ISBN: 9780306437816
Category : Medical
Languages : en
Pages : 598
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Book Description
This monograph thoroughly examines the latest theory and research concerning spinal cord mechanisms of sensory processing. The book begins with a historical review of the organization of the peripheral nervous system is outlined in terms of sensory receptors and primary afferent axons. The authors examine the dorsal horn and the structure and function of dorsal horn internurons, and neurophysiological evidence concerning the location of sensory pathways in the spinal cord white matter. After te dorsal column, dorshlateral fasciculus, and the ventral quadrant are covered, the final chapter summarizes knowledge on receptors and spinal cord pathways of various sensations, including touch-pressure, flutter-vibration, pain, temperature, position sense, visceral sensation, and descending control systems.
Author: Annika B. Malmberg
Publisher: Springer Science & Business Media
ISBN: 9783764362379
Category : Medical
Languages : en
Pages : 278
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Book Description
Numerous improvements in our understanding of the mechanisms that underlie neuropathic pain states have come from the development of animal models, most of which involve partial peripheral nerve injury. The animal models have shown that nerve injury initiates a cascade of events resulting in altered neurochemistry and molecular biology of the peripheral neurons, the dorsal root ganglion cell, and changes in neurotransmitter and receptor expression in the dorsal horn of the spinal cord. Moreover, nerve injury produces anatomical changes with functional consequences. This volume summarises the current understanding of the pathophysiological processes in the peripheral and central nervous system that contribute to the neuropathic pain. It provides a timely review of neuropathic pain mechanisms, written by experts in the field.
Author: National Institute of Neurological and Communicative Disorders and Stroke
Publisher:
ISBN:
Category : Cerebrovascular disease
Languages : en
Pages : 400
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Book Description
Author: Gary S. Firestein
Publisher: Elsevier Health Sciences
ISBN: 032341494X
Category : Medical
Languages : en
Pages : 2561
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Book Description
Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein’s Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases. An ideal balance of the basic science you need to know and how to apply that information to clinical practice. An integrated chapter format allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. New content on the latest diagnostic perspectives and approaches to therapy, including five brand-new chapters: Metabolic Regulation of Immunity, Principles of Signaling, Research Methods in the Rheumatic Diseases, Novel Intracellular Targeting Agents, and IgG4-Related Diseases. New and expanded chapter topics on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. More schematic diagrams clearly summarize information and facilitate understanding.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1504
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Book Description
Author: National Institutes of Health (U.S.). Division of Research Grants
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1212
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Book Description
Author: Gary S. Firestein
Publisher: Elsevier Health Sciences
ISBN: 0323639216
Category : Medical
Languages : en
Pages : 2742
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Book Description
Through 10 outstanding editions, Kelley & Firestein's Textbook of Rheumatology has provided authoritative, in-depth guidance in rheumatology with an ideal balance of basic science and clinical application. The 11th Edition of this classic text continues this tradition of excellence, while keeping you abreast of recent advances in genetics and the microbiome, new therapies such as biologics and biosimilars, and other rapid changes in the field. It provides comprehensive, global coverage of all aspects of diagnosis, screening, and treatment in both adults and children, in a user-friendly, full color reference. - Covers everything from basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes—including key data on therapeutic outcomes to better inform clinical decision making. - Includes new chapters on Innate Lymphoid Cells and Natural Killer Cells, Pathogenesis of Inflammasome Mediated Diseases, Bisphosphonates, Ultrasound Evaluation of the Musculoskeletal System, and Evaluation of Monoarticular and Polyarticular Arthritis. - Features 1,200 high-quality illustrations, including superb line art, quick-reference tables, and full-color clinical photographs. - Shares the knowledge and expertise of internationally renowned scientists and clinicians, including new editor Dr. Gary Koretzky, specialist in immunology and rheumatology. - Demonstrates the complete musculoskeletal exam in online videos, including abnormal findings and the arthroscopic presentation of diseased joints. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Author: Richard Fish
Publisher: Academic Press
ISBN: 0080559832
Category : Medical
Languages : en
Pages : 677
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Book Description
Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery. Fully revised and updated this new edition provides the reader with agents, methods, and techniques for anesthesia and analgesia that ensure humane and successful procedural outcomes. - Provides researchers with the most comprehensive and up-to-date review of the use of anesthesia and analgesia in laboratory animals - Thoroughly updated with new material on ferrets, birds, reptiles, amphibians, fish, and invertebrates - Includes hot topic areas such as pain research, ethical issues, legal issues, and imaging studies
Author: Josef Donnerer
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805580045
Category : Medical
Languages : en
Pages : 226
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Book Description
Neurochemical transmission accounts for the majority of information transfer both in the central and peripheral nervous system. The initial findings centred around the experimental work of the two Nobel Prize winners Sir Henry H. Dale and Otto Loewi as well as Wilhelm Feldberg. Their historical findings opened the door to further investigations and extended the list of neurotransmitters to many others such as amino acids, peptides, purines and nitric oxide. In the first part, the publication provides fascinating insights into the life of the three scientists. Their personality and scientific approach are presented through autobiographical sketches and personal memories by authors. Various comments and details of the atmosphere in the laboratory complete the picture of the conditions at the time. The second part is dedicated to the history of the substances, such as neurotransmitters, their antagonists and analogues. The stories of these substances are presented to the reader in a succinct way, including many anecdotes and unusual events on the way to their therapeutic application. Contents Preface Introduction Otto Loewi Otto Loewi Introductory Remarks Autobiographic Sketch. By O. Loewi Otto Loewi 1873-1961. By H.H. Dale Otto Loewi. By F. Brucke Loewi's Time in Graz Comment on Loewi's Dream An Overlooked Parallel to Kekule's Dream: The Discovery of the Chemical Transmission of Nerve Impulses by Otto Loewi. By U. Weiss and R.A. Brown The Loewi Family's Way to the New World Comment on the Film Nobelpreistrager Otto Loewi Henry Hallett Dale Henry Hallett Dale Introductory Remarks Henry Hallett Dale 1875-1968. By W. Feldberg Fifty Years after the Nobel Prize Award to H.H. Dale and Otto Loewi. By G.B. Koelle Religious Reflections of Dale and Loewi Wilhelm Feldberg Wilhelm Feldberg Introductory Remarks The Early History of Synaptic and Neuromuscular Transmission by Acetylcholine: Reminiscences of an Eye Witness. By W. Feldberg From the History of Scientists to that of Neurotransmitters A Substance Isolated from Brain, Synthesized and Called Neurin: Acetylcholine Adrenaline, Noradrenaline and Dopamine: The Catecholamines Enteramine and Serotonin: Two Names and Three Functions of 5-Hydroxytryptamine Histamine: One Substance and Three Functions The Amino Acid Transmitter Family A Cloud of Peptides Substance P Calcitonin Gene-Related Peptide Neuropeptide, Galanine and Vasoactive Intephinal Polypeptide Opioid Peptides Nitric Oxide ATP and Adenosine Peripheral Neurogenic Stimulators Neurotransmission in the Central Nervous System From Transmitter to Receptor: Progress within 50 Years.
