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Author: Nicolas Le Brun
Publisher:
ISBN:
Category :
Languages : fr
Pages : 146
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Book Description
Introduction : Présentation du système de pharmacovigilance : organisations, missions, avantages et limites de la notification spontanée. Contexte : Suite à l'affaire du Médiator®, un bilan de ce système, pointant le problème de la sous-notification d'effets indésirables, a été réalisé par l'IGAS qui propose des pistes d'améliorations. Un état des lieux de la formation sur la pharmacovigilance lors des études médicales, présente l'interne de médecine générale comme une cible privilégiée. Questionnaire : L'enquête par questionnaire remis aux internes, dresse un bilan des connaissances et de leurs attentes de formation. La discussion des résultats a permis de proposer des améliorations, dont l'organisation d'un enseignement universitaire, sur les modalités de la déclaration des effets indésirables et la sécurité d'emploi des médicaments. Proposition de formation pour les internes : Modalités pratiques (formation interactive sous forme d'analyse de cas cliniques) et retombées attendues.
Author: Nicolas Le Brun
Publisher:
ISBN:
Category :
Languages : fr
Pages : 146
Get Book Here
Book Description
Introduction : Présentation du système de pharmacovigilance : organisations, missions, avantages et limites de la notification spontanée. Contexte : Suite à l'affaire du Médiator®, un bilan de ce système, pointant le problème de la sous-notification d'effets indésirables, a été réalisé par l'IGAS qui propose des pistes d'améliorations. Un état des lieux de la formation sur la pharmacovigilance lors des études médicales, présente l'interne de médecine générale comme une cible privilégiée. Questionnaire : L'enquête par questionnaire remis aux internes, dresse un bilan des connaissances et de leurs attentes de formation. La discussion des résultats a permis de proposer des améliorations, dont l'organisation d'un enseignement universitaire, sur les modalités de la déclaration des effets indésirables et la sécurité d'emploi des médicaments. Proposition de formation pour les internes : Modalités pratiques (formation interactive sous forme d'analyse de cas cliniques) et retombées attendues.
Author: Konrad Bork
Publisher: W.B. Saunders Company
ISBN:
Category : Medical
Languages : en
Pages : 448
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Book Description
Author: Corinne Grenier
Publisher: John Wiley & Sons
ISBN: 1786307073
Category : Business & Economics
Languages : en
Pages : 72
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Book Description
How can healthcare systems be transformed by reimagining their multiple silos to favor processes and practices that are more responsive to local, horizontal initiatives? Altering Frontiers analyzes numerous experiences, using a multidisciplinary approach, paying attention to certain actors, collectives and organizational arrangements. Through this work, levers are identified that promote lasting transformation: recognizing the legitimacy of the practices of many who are often "invisible"; trusting those who know their intervention territory; investing in methodological support; taking advantage of tools and procedures such as instruments for strategic and managerial discussion; and developing the capacity to absorb innovative ideas and experiences that circulate within the environment.
Author: Hugo Slim
Publisher: Oxford University Press
ISBN: 0190613327
Category : Social Science
Languages : en
Pages : 374
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Book Description
Humanitarians are required to be impartial, independent, professionally competent and focused only on preventing and alleviating human suffering. It can be hard living up to these principles when others do not share them, while persuading political and military authorities and non-state actors to let an agency assist on the ground requires savvy ethical skills. Getting first to a conflict or natural catastrophe is only the beginning, as aid workers are usually and immediately presented with practical and moral questions about what to do next. For example, when does working closely with a warring party or an immoral regime move from practical cooperation to complicity in human rights violations? Should one operate in camps for displaced people and refugees if they are effectively places of internment? Do humanitarian agencies inadvertently encourage ethnic cleansing by always being ready to 'mop-up' the consequences of scorched earth warfare? This book has been written to help humanitarians assess and respond to these and other ethical dilemmas.
Author: Frédéric Bourdier
Publisher: Centre for East and South-East Asian Studies Lund University
ISBN:
Category : AIDS (Disease)
Languages : en
Pages : 36
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Book Description
Author: Alan D. Lopez
Publisher: World Bank Publications
ISBN: 0821362631
Category : Medical
Languages : en
Pages : 511
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Book Description
Strategic health planning, the cornerstone of initiatives designed to achieve health improvement goals around the world, requires an understanding of the comparative burden of diseases and injuries, their corresponding risk factors and the likely effects of invervention options. The Global Burden of Disease framework, originally published in 1990, has been widely adopted as the preferred method for health accounting and has become the standard to guide the setting of health research priorities. This publication sets out an updated assessment of the situation, with an analysis of trends observed since 1990 and a chapter on the sensitivity of GBD estimates to various sources of uncertainty in methods and data.
Author: Irene Papanicolas
Publisher: McGraw-Hill Education (UK)
ISBN: 033524727X
Category : Medical
Languages : en
Pages : 418
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Book Description
International comparison of health system performance has become increasingly popular, made possible by the rapidly expanding availability of health data. It has become one of the most important levers for prompting health system reform. Yet, as the demand for transparency and accountability in healthcare increases, so too does the need to compare data from different health systems both accurately and meaningfully. This timely and authoritative book offers an important summary of the current developments in health system performance comparison. It summarises the current state of efforts to compare systems, and identifies and explores the practical and conceptual challenges that occur. It discusses data and methodological challenges, as well as broader issues such as the interface between evidence and practice. The book draws out the priorities for future work on performance comparison, in the development of data sources and measurement instruments, analytic methodology, and assessment of evidence on performance. It concludes by presenting the key lessons and future priorities, and in doing so offers a rich source of material for policy-makers, their analytic advisors, international agencies, academics and students of health systems.
Author: Toby L. Simon
Publisher: John Wiley & Sons
ISBN: 1119012996
Category : Medical
Languages : en
Pages : 754
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Book Description
Rossi's Principles of Transfusion Medicine is the most comprehensive and practical reference on transfusion science and medicine available Led by a world class Editor team, including two past-presidents of AABB, a past- President of the American Board of Pathology and members of the FDA Blood Products Advisory Committee , and international contributor team Comprehensive reference resource, considered the gold standard in transfusion Covers current hot topics such as donor care – including the frequency of donation and management of iron deficiency/status), patient blood management, hemovigilance, cstem cell therapies, and global aspects of the organization of transfusion and transplant services New material on molecular immunohematology Companion website includes figures, full text and references
Author:
Publisher: Commonwealth Secretariat
ISBN: 9780850926552
Category : Health & Fitness
Languages : en
Pages : 190
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Book Description
Women, especially young women, have increasing infection rates from HIV/AIDS and the death rate among women is now almost as high as men.
Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher: World Health Organization
ISBN:
Category : Health & Fitness
Languages : en
Pages : 536
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Book Description
Evaluates the carcinogenic risks to humans posed by the use of four antiretroviral agents four DNA topoisomerase II inhibitors used in the treatment of cancer and an additional three pharmaceutical agents (hydroxyures phenolphthalein and vitamin K substances). The volume marks the first IARC evaluation of nucleoside analogs that act as antiviral agents. The evaluation responds in part to recent findings that zidovudine (AZT) an effective antiretroviral agent now being given to pregnant HIV-infected women to prevent maternal-to-fetal transmission of the virus is a transplacental carcinogen in mice. The opening monograph evaluates the carcinogenicity to humans of the antiretroviral nucleoside analogs zidovudine (AZT) zalcitabine (ddC) and didanosine (ddI) and the antiherpesvirus drug aciclovir. Of these aciclovir and didanosine could not be classified on the basis of available data. For zidovudine transplacental administration to mice resulted in an increased incidence and multiplicity of lung and liver tumours and in an increased incidence of female reproductive tract tumours in one study but not in another involving treatment at a lower dose. Despite observation of toxic effects in some studies of humans human carcinogenicity data were judged to provide inadequate evidence of carcinogenicity in humans. Zidovudine was classified as possibly carcinogenic to humans. Similar weaknesses in human carcinogenicity data for zalcitabine which consistently induces thymic lymphomas in mice resulted in its classification as possibly carcinogenic to humans. The second monograph evaluates four DNA topoisomerase II inhibitors: etoposide teniposide mitoxantrone and amsacrine. Of these etoposide - one of the most widely used and effective cytotoxic drugs in combination therapy - was classified as probably carcinogenic to humans and etoposide in combination with cisplatin and bleomycin was judged to be carcinogenic to humans. Teniposide was classified as probably carcinogenic to humans and mitoxantrone and amsacrine were classified as possibly carcinogenic to humans. Of the three pharmaceutical agents evaluated in the final monograph hydroxyurea which is widely used in cancer treatment and increasingly in combination with didanosine in HIV infection could not be classified. Phenolphthalein a widely used laxative now being withdrawn from the market in many countries because of toxicological concerns was classified as possibly carcinogenic. Vitamin K substances could not be classified on the basis of available evidence.
