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Author: Thomas Nickles
Publisher: Taylor & Francis
ISBN: 9789027710925
Category : History
Languages : en
Pages : 418
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Book Description
The history of science is articulated by moments of discovery. Yet, these 'moments' are not simple or isolated events in science. Just as a scientific discovery illuminates our understanding of nature or of society, and reveals new connections among phenomena, so too does the history of scientific activity and the analysis of scientific reasoning illuminate the processes which give rise to moments of discovery and the complex network of consequences which follow upon such moments. Understanding discovery has not been, until recently, a major concern of modem philosophy of science. Whether the act of discoyery was regarded as mysterious and inexplicable, or obvious and in no need of explanation, modem philosophy of science in effect bracketed the question. It concentrated instead on the logic of scientific explanation or on the issues of validation or justification of scientific theories or laws. The recent revival of interest in the context of discovery, indeed in the acts of discovery, on the part of philosophers and historians of science, represents no one particular method'ological or philosophical orientation. It proceeds as much from an empiricist and analytical approach as from a sociological or historical one; from considerations of the logic of science as much as from the alogical or extralogical contexts of scientific tho'¢tt and practice. But, in general, this new interest focuses sharply on the actual historical and contem porary cases of scientific discovery, and on an examination of the act or moment of discovery in situ.
Author: Thomas Nickles
Publisher: Taylor & Francis
ISBN: 9789027710925
Category : History
Languages : en
Pages : 418
Get Book Here
Book Description
The history of science is articulated by moments of discovery. Yet, these 'moments' are not simple or isolated events in science. Just as a scientific discovery illuminates our understanding of nature or of society, and reveals new connections among phenomena, so too does the history of scientific activity and the analysis of scientific reasoning illuminate the processes which give rise to moments of discovery and the complex network of consequences which follow upon such moments. Understanding discovery has not been, until recently, a major concern of modem philosophy of science. Whether the act of discoyery was regarded as mysterious and inexplicable, or obvious and in no need of explanation, modem philosophy of science in effect bracketed the question. It concentrated instead on the logic of scientific explanation or on the issues of validation or justification of scientific theories or laws. The recent revival of interest in the context of discovery, indeed in the acts of discovery, on the part of philosophers and historians of science, represents no one particular method'ological or philosophical orientation. It proceeds as much from an empiricist and analytical approach as from a sociological or historical one; from considerations of the logic of science as much as from the alogical or extralogical contexts of scientific tho'¢tt and practice. But, in general, this new interest focuses sharply on the actual historical and contem porary cases of scientific discovery, and on an examination of the act or moment of discovery in situ.
Author: Thomas Nickles
Publisher: Springer Science & Business Media
ISBN: 9400990154
Category : Science
Languages : en
Pages : 398
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Book Description
The history of science is articulated by moments of discovery. Yet, these 'moments' are not simple or isolated events in science. Just as a scientific discovery illuminates our understanding of nature or of society, and reveals new connections among phenomena, so too does the history of scientific activity and the analysis of scientific reasoning illuminate the processes which give rise to moments of discovery and the complex network of consequences which follow upon such moments. Understanding discovery has not been, until recently, a major concern of modem philosophy of science. Whether the act of discoyery was regarded as mysterious and inexplicable, or obvious and in no need of explanation, modem philosophy of science in effect bracketed the question. It concentrated instead on the logic of scientific explanation or on the issues of validation or justification of scientific theories or laws. The recent revival of interest in the context of discovery, indeed in the acts of discovery, on the part of philosophers and historians of science, represents no one particular method'ological or philosophical orientation. It proceeds as much from an empiricist and analytical approach as from a sociological or historical one; from considerations of the logic of science as much as from the alogical or extralogical contexts of scientific tho'¢tt and practice. But, in general, this new interest focuses sharply on the actual historical and contem porary cases of scientific discovery, and on an examination of the act or moment of discovery in situ.
Author: Newton Copp
Publisher: MIT Press
ISBN: 9780262531115
Category : Reference
Languages : en
Pages : 446
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Book Description
Discovery, Innovation, and Risk presents brief descriptions of selected scientific principles in the context of interesting technological examples to illustrate the complex interplay among science, engineering, and society.
Author: Rebecca Hite
Publisher: National Science Teachers Association
ISBN: 9781681406145
Category : Science
Languages : en
Pages : 0
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Book Description
"Who knew that small, plant-eating mammals called pikas helped scientists find new ways to survive extreme weather events, or that algae could be used as airplane fuel? Your students will learn about amazing scientific advancements like these when you use the lessons in Discovery Engineering in Biology: Case Studies for Grades 6-12. The book is a lively way to blend history, real-world perspectives, 21st-century skills, and engineering into your biology or STEM curriculum. Like Discovery Engineering in Physical Science (see p. XX), this book features case studies about observations and accidental discoveries that led to the invention of new products and problem-solving applications. The 20 lessons are both flexible and easy to use. After reading a historical account of an actual innovation, students explore related activities that connect to such topics as molecules and organisms, ecosystems, heredity, and biological evolution. Then they're prompted to think creatively about science from serendipity. They conduct research, analyze data, and use the engineering design process to develop products or applications of their own. Students are sure to be intrigued by investigations with titles such as "Vindicating Venom: Using Biological Mechanisms to Treat Diseases and Disorders" and "Revealing Repeats: The Accidental Discovery of DNA Fingerprinting." Discovery Engineering in Biology is an engaging way to help students discover that when accidents happen, the outcome can be an incredible innovation"--
Author: Thomas Nickles
Publisher: Springer Science & Business Media
ISBN: 9400989865
Category : Science
Languages : en
Pages : 389
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Book Description
It is fast becoming a cliche that scientific discovery is being rediscovered. For two philosophical generations (that of the Founders and that of the Followers of the logical positivist and logical empiricist movements), discovery had been consigned to the domain of the intractable, the ineffable, the inscrutable. The philosophy of science was focused on the so-called context of justification as its proper domain. More recently, as the exclusivity of the logical reconstruc tion program in philosophy of science came under question, and as the critique of justification developed within the framework of logical and epistemological analysis, the old question of scientific discovery, which had been put on the back burner, began to emerge once again. Emphasis on the relation of the history of science to the philosophy of science, and attention to the question of theory change and theory replacement, also served to legitimate a new concern with the origins of scientific change to be found within discovery and invention. How welcome then to see what a wide range of issues and what a broad representation of philosophers and historians of science have been brought together in the present two volumes of the Boston Studies in the Philosophy of Science! For what these volumes achieve, in effect, is the continuation of a tradition which had once been strong in the philosophy of science - namely, that tradition which addressed the question of scientific discovery as a central question in the understanding of science.
Author: Xianhai Huang
Publisher: John Wiley & Sons
ISBN: 0470601817
Category : Medical
Languages : en
Pages : 488
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Book Description
Learn why some drug discovery and development efforts succeed . . . and others fail Written by international experts in drug discovery and development, this book sets forth carefully researched and analyzed case studies of both successful and failed drug discovery and development efforts, enabling medicinal chemists and pharmaceutical scientists to learn from actual examples. Each case study focuses on a particular drug and therapeutic target, guiding readers through the drug discovery and development process, including drug design rationale, structure-activity relationships, pharmacology, drug metabolism, biology, and clinical studies. Case Studies in Modern Drug Discovery and Development begins with an introductory chapter that puts into perspective the underlying issues facing the pharmaceutical industry and provides insight into future research opportunities. Next, there are fourteen detailed case studies, examining: All phases of drug discovery and development from initial idea to commercialization Some of today's most important and life-saving medications Drugs designed for different therapeutic areas such as cardiovascular disease, infection, inflammation, cancer, metabolic syndrome, and allergies Examples of prodrugs and inhaled drugs Reasons why certain drugs failed to advance to market despite major research investments Each chapter ends with a list of references leading to the primary literature. There are also plenty of tables and illustrations to help readers fully understand key concepts, processes, and technologies. Improving the success rate of the drug discovery and development process is paramount to the pharmaceutical industry. With this book as their guide, readers can learn from both successful and unsuccessful efforts in order to apply tested and proven science and technologies that increase the probability of success for new drug discovery and development projects.
Author: Joel Barrish
Publisher: Royal Society of Chemistry
ISBN: 1849731268
Category : Medical
Languages : en
Pages : 397
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Book Description
Accounts in Drug Discovery describes recent case studies in medicinal chemistry with a particular emphasis on how the inevitable problems that arise during any project can be surmounted or overcome. The Editors cover a wide range of therapeutic areas and medicinal chemistry strategies, including lead optimization starting from high-throughput screening "hits" as well as rational, structure-based design. The chapters include "follow-ons" and "next generation" compounds that aim to improve upon first-generation agents. This volume surveys the range of challenges commonly faced by medicinal chemistry researchers, including the optimization of metabolism and pharmacokinetics, toxicology, pharmaceutics and pharmacology, including proof-of-concept in the clinic for novel biological targets. The case studies include medicinal chemistry stories on recently approved and marketed drugs, but also chronicle "near-misses," i.e. exemplary compounds that may have proceeded well into the clinic but for various reasons did not result in a successful registration. As the vast majority of projects fail prior to registration, much can be learned from such narratives. By sharing a wide range of drug discovery experiences and information across the community of medicinal chemists in both industry and academia, the Editors believe that these accounts will provide insights into the art of medicinal chemistry as it is currently practiced and will help to serve the needs of active medicinal chemists.
Author: Theodore H. Tulchinsky
Publisher: Academic Press
ISBN: 0128045868
Category : Technology & Engineering
Languages : en
Pages : 605
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Book Description
Case Studies in Public Health contains selected case studies of some of the most important and influential moments in medicine and epidemiology. The cases chosen for this collection represent a wide array of public health issues that go into the makeup of what can be termed the New Public Health (NPH), which includes traditional public health, such as sanitation, hygiene and infectious disease control, but widens its perspective to include the organization, financing and quality of health care services in a much broader sense. Each case study is presented in a systematic fashion to facilitate learning, with the case, background, current relevance, economic issues, ethical issues, conclusions, recommendation and references discussed for each case. The book is a valuable resource for advanced students and researchers with specialized knowledge who need further information on the general background and history of public health and important scientific discoveries within the field. It is an ideal resource for students in public health, epidemiology, medicine, anthropology, and sociology, and for those interested in how to apply lessons from the past to present and future research. - Explores the history of public health through important scientific events and flashpoints - Presents case studies in a clear, direct style that is easy to follow - Uses a systematic approach to help learn lessons from the past and apply them to the present
Author: Linda C. Gundersen
Publisher: John Wiley & Sons
ISBN: 1119067782
Category : Education
Languages : en
Pages : 339
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Book Description
Science is built on trust. The assumption is that scientists will conduct their work with integrity, honesty, and a strict adherence to scientific protocols. Written by geoscientists for geoscientists, Scientific Integrity and Ethics in the Geosciences acquaints readers with the fundamental principles of scientific ethics and shows how they apply to everyday work in the classroom, laboratory, and field. Resources are provided throughout to help discuss and implement principles of scientific integrity and ethics. Volume highlights include: Examples of international and national codes and policies Exploration of the role of professional societies in scientific integrity and ethics References to scientific integrity and ethics in publications and research data Discussion of science integrity, ethics, and geoethics in education Extensive coverage of data applications Scientific Integrity and Ethics in the Geosciences is a valuable resource for students, faculty, instructors, and scientists in the geosciences and beyond. It is also useful for geoscientists working in industry, government, and policymaking. Read an interview with the editors to find out more: https://eos.org/editors-vox/ethics-crucial-for-the-future-of-the-geosciences
Author: Roger Gomm
Publisher: SAGE
ISBN: 1446275698
Category : Social Science
Languages : en
Pages : 288
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Book Description
This is the most comprehensive guide to the current uses and importance of case study methods in social research. The editors bring together key contributions from the field which reflect different interpretations of the purpose and capacity of case study research. The address issues such as: the problem of generalizing from study of a small number of cases; and the role of case study in developing and testing theories. The editors offer in-depth assessments of the main arguments. An annotated bibliography of the literature dealing with case study research makes this an exhaustive and indispensable guide.
