The Science of Cancer

The Science of Cancer PDF Author: Scientific American Editors
Publisher: Scientific American
ISBN: 1466859075
Category : Medical
Languages : en
Pages : 225

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Book Description
The past few years have seen tremendous strides in our understanding of cancer, including new hypotheses about its genetic origins and new treatment alternatives using the body’s own immune response. In this eBook, The Science of Cancer, we examine what we know and what we’re finding out about this scourge of humankind. We delve into the molecular basis and complex causes of cancer, the arguments for and against screenings, new and targeted therapies, and minimizing risk. In “How Cancer Arises,” Robert Weinberg presents what has been the central dogma of cancer genetics, which says that a handful of essential mutations in specific genes lead to tumor growth; however, recent discoveries are challenging this theory, as we see in “Untangling the Roots of Cancer” and “Stem Cells: The Real Culprits in Cancer?” Early detection of cancer is important for treatment, but not all screening tests are created equal. In “The Great Prostate Cancer Debate,” Mark Garnick lays out the controversy over the value of the prostate-specific antigen test for prostate cancer and the rationale against screening. With our increasing knowledge of cancer’s causes, exciting targeted therapies are on the rise, including homing in on stem cells, making use of viruses, and manipulating the immune system as we see in “A New Ally against Cancer,” which focuses on treatment with therapeutic vaccines. Does this mean a cure is around the corner? Perhaps not, according to Scientific American Editor Dina Fine Maron in “Can We Truly ‘Cure’ Cancer?” But with remission rates rising for certain types of cancers and with new discoveries opening up further avenues of research, there is reason for optimism.

The Science of Cancer

The Science of Cancer PDF Author: Scientific American Editors
Publisher: Scientific American
ISBN: 1466859075
Category : Medical
Languages : en
Pages : 225

Get Book

Book Description
The past few years have seen tremendous strides in our understanding of cancer, including new hypotheses about its genetic origins and new treatment alternatives using the body’s own immune response. In this eBook, The Science of Cancer, we examine what we know and what we’re finding out about this scourge of humankind. We delve into the molecular basis and complex causes of cancer, the arguments for and against screenings, new and targeted therapies, and minimizing risk. In “How Cancer Arises,” Robert Weinberg presents what has been the central dogma of cancer genetics, which says that a handful of essential mutations in specific genes lead to tumor growth; however, recent discoveries are challenging this theory, as we see in “Untangling the Roots of Cancer” and “Stem Cells: The Real Culprits in Cancer?” Early detection of cancer is important for treatment, but not all screening tests are created equal. In “The Great Prostate Cancer Debate,” Mark Garnick lays out the controversy over the value of the prostate-specific antigen test for prostate cancer and the rationale against screening. With our increasing knowledge of cancer’s causes, exciting targeted therapies are on the rise, including homing in on stem cells, making use of viruses, and manipulating the immune system as we see in “A New Ally against Cancer,” which focuses on treatment with therapeutic vaccines. Does this mean a cure is around the corner? Perhaps not, according to Scientific American Editor Dina Fine Maron in “Can We Truly ‘Cure’ Cancer?” But with remission rates rising for certain types of cancers and with new discoveries opening up further avenues of research, there is reason for optimism.

Scientific American Molecular Oncology

Scientific American Molecular Oncology PDF Author: J. Michael Bishop
Publisher: Mosby Incorporated
ISBN: 9780894540233
Category : Medical
Languages : en
Pages : 255

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Book Description
This exciting new book approaches cancer diagnosis and therapy from the molecular level. It emphasizes the ability to isolate genes through the use of recombinant DNA. Full-color!

Scientific American

Scientific American PDF Author:
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 572

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Book Description


Introduction to Molecular Medicine

Introduction to Molecular Medicine PDF Author: Dennis W. Ross
Publisher: Springer Science & Business Media
ISBN: 9780387953724
Category : Medical
Languages : en
Pages : 180

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Book Description
Presents the discoveries, basic scientific concepts, and sense of excitement that surround the revolution in molecular medicine. The scientific basis of molecular medicine is presented simply and directly, but at a level of technical detail sufficient for the reader to appreciate the power of recombinant DNA technology. The volume is clinically oriented throughout. Annotation copyrighted by Book News, Inc., Portland, OR

Molecular Oncology

Molecular Oncology PDF Author: Frank Joseph Rauscher (III)
Publisher: Cambridge University Press
ISBN: 0521876621
Category : Medical
Languages : en
Pages : 985

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Book Description
Reviews the origins of molecular oncology, including technologies for cancer analysis, key pathways in human malignancies, and available pharmacologic therapies.

Molecular Oncology of Breast Cancer

Molecular Oncology of Breast Cancer PDF Author: Jeffrey Stuart Ross
Publisher: Jones & Bartlett Learning
ISBN: 9780763748104
Category : Medical
Languages : en
Pages : 642

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Book Description
The first comprehensive reference to focus on the molecular development and treatment of the disease, Molecular Oncology of Breast Cancer provides authoritative information across the spectrum of modern breast cancer research and clinical care. Edited by two world-class experts in cancer pathology, drug development, and patient management, with contributions from over 50 experts, this ground-breaking text describes the genes, proteins, and biologic pathways that are being evaluated today and will be tested in the future to derive the molecular signature of each newly diagnosed breast cancer. For the first time, readers can now obtain, in a single volume, up-to-date information on how molecular-based tests are being used to identify predisposition, provide earliest detection, decide classification based on genetic fingerprint and predict therapy-specific outcomes. MOBC includes unique chapters on functional imaging and the impact of targeted therapies on the FDA approval process. This book gives readers vital, up-to-date information on important molecular discoveries that affect the everyday management of the breast cancer patient.

Scientific American Molecular Cardiovascular Medicine

Scientific American Molecular Cardiovascular Medicine PDF Author: Edgar Haber
Publisher: Mosby
ISBN:
Category : Medical
Languages : en
Pages : 360

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Book Description


Evolution of Translational Omics

Evolution of Translational Omics PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309224187
Category : Science
Languages : en
Pages : 354

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Book Description
Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Molecular Oncology Principles and Recent Advances

Molecular Oncology Principles and Recent Advances PDF Author: Javier Camacho
Publisher: Bentham Science Publishers
ISBN: 1608050165
Category : Medical
Languages : en
Pages : 237

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Book Description
"Cancer is one of the major causes of death worldwide. Despite hundreds of clinical trials currently in progress for cancer patients, the success rate is still very low. Understanding the molecular aspects of cancer development, the discovery of new molecu"

The Basic Science of Oncology

The Basic Science of Oncology PDF Author: Ian Tannock
Publisher: McGraw Hill Professional
ISBN: 9780071387743
Category : Medical
Languages : en
Pages : 596

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Book Description
This concise text examines cancer causation and biology as well as the biology underlying cancer treatment. Thoroughly updated and reorganized with five new chapters, the Fourth Edition emphasizes new development in molecular biology, hormone therapy, and the pharmacology of anti-cancer drugs. Features updated coverage of the basic science of radiotherapy and experimental radiation in addition to expansive coverage of new drugs developments.