Author:
Publisher: Thieme
ISBN: 3131766018
Category : Science
Languages : en
Pages : 926
Book Description
The two volumes "Science of Synthesis: Multicomponent Reactions" critically review the state of the art of domino, sequential, and consecutive multicomponent reactions in what is a highly dynamic field. They serve as the basis for practical application to reach the goals of diversity-oriented synthesis, reaction design, and novel synthetic concepts. As is typical for the Science of Synthesis series, the reference work on multicomponent reactions presents the best synthetic methods as judged by experts in the field and includes typical and general experimental procedures. The volume "Reactions Involving an alpha,beta-Unsaturated Carbonyl Compound as Electrophilic Component" covers the following topics: Michael Additions Wittig Reactions Cycloadditions Reactions Involving an alpha,beta-Unsaturated Carbonyl Compound as Electrophilic Component with Electron-Deficient Alkynes as Electrophiles Reactions with Cycloaddition as the Key Step Boron-Mediated Multicomponent Reactions Silicon-Mediated Multicomponent Reactions Free-Radical Mediated Multicomponent Reactions Metal-Mediated Multicomponent Reactions
Science of Synthesis: Multicomponent Reactions Vol. 2
Author:
Publisher: Thieme
ISBN: 3131766018
Category : Science
Languages : en
Pages : 926
Book Description
The two volumes "Science of Synthesis: Multicomponent Reactions" critically review the state of the art of domino, sequential, and consecutive multicomponent reactions in what is a highly dynamic field. They serve as the basis for practical application to reach the goals of diversity-oriented synthesis, reaction design, and novel synthetic concepts. As is typical for the Science of Synthesis series, the reference work on multicomponent reactions presents the best synthetic methods as judged by experts in the field and includes typical and general experimental procedures. The volume "Reactions Involving an alpha,beta-Unsaturated Carbonyl Compound as Electrophilic Component" covers the following topics: Michael Additions Wittig Reactions Cycloadditions Reactions Involving an alpha,beta-Unsaturated Carbonyl Compound as Electrophilic Component with Electron-Deficient Alkynes as Electrophiles Reactions with Cycloaddition as the Key Step Boron-Mediated Multicomponent Reactions Silicon-Mediated Multicomponent Reactions Free-Radical Mediated Multicomponent Reactions Metal-Mediated Multicomponent Reactions
Publisher: Thieme
ISBN: 3131766018
Category : Science
Languages : en
Pages : 926
Book Description
The two volumes "Science of Synthesis: Multicomponent Reactions" critically review the state of the art of domino, sequential, and consecutive multicomponent reactions in what is a highly dynamic field. They serve as the basis for practical application to reach the goals of diversity-oriented synthesis, reaction design, and novel synthetic concepts. As is typical for the Science of Synthesis series, the reference work on multicomponent reactions presents the best synthetic methods as judged by experts in the field and includes typical and general experimental procedures. The volume "Reactions Involving an alpha,beta-Unsaturated Carbonyl Compound as Electrophilic Component" covers the following topics: Michael Additions Wittig Reactions Cycloadditions Reactions Involving an alpha,beta-Unsaturated Carbonyl Compound as Electrophilic Component with Electron-Deficient Alkynes as Electrophiles Reactions with Cycloaddition as the Key Step Boron-Mediated Multicomponent Reactions Silicon-Mediated Multicomponent Reactions Free-Radical Mediated Multicomponent Reactions Metal-Mediated Multicomponent Reactions
Science of Synthesis: Multicomponent Reactions Vol. 1
Author: Thomas J. J. Müller
Publisher: Thieme
ISBN: 313176581X
Category : Science
Languages : en
Pages : 999
Book Description
The two volumes "Science of Synthesis: Multicomponent Reactions" critically review the state of the art of domino, sequential, and consecutive multicomponent reactions in what is a highly dynamic field. They serve as the basis for practical application to reach the goals of diversity-oriented synthesis, reaction design, and novel synthetic concepts. As is typical for the Science of Synthesis series, the reference work on multicomponent reactions presents the best synthetic methods as judged by experts in the field and includes typical and general experimental procedures. The volume "Reactions Involving a Carbonyl Compound as Electrophilic Component" covers the following topics: Biginelli Reaction Strecker Reaction Hantzsch Pyridine Synthesis Mannich Reaction Petasis Reaction Willgerodt-Kindler Reaction Kabachnik-Fields Reaction Passerini Reaction Ugi Reaction Gewald Reaction
Publisher: Thieme
ISBN: 313176581X
Category : Science
Languages : en
Pages : 999
Book Description
The two volumes "Science of Synthesis: Multicomponent Reactions" critically review the state of the art of domino, sequential, and consecutive multicomponent reactions in what is a highly dynamic field. They serve as the basis for practical application to reach the goals of diversity-oriented synthesis, reaction design, and novel synthetic concepts. As is typical for the Science of Synthesis series, the reference work on multicomponent reactions presents the best synthetic methods as judged by experts in the field and includes typical and general experimental procedures. The volume "Reactions Involving a Carbonyl Compound as Electrophilic Component" covers the following topics: Biginelli Reaction Strecker Reaction Hantzsch Pyridine Synthesis Mannich Reaction Petasis Reaction Willgerodt-Kindler Reaction Kabachnik-Fields Reaction Passerini Reaction Ugi Reaction Gewald Reaction
Science of Synthesis Knowledge Updates 2014 Vol. 2
Author: Mogens Brøndsted Nielsen
Publisher: Thieme
ISBN: 3131762713
Category : Science
Languages : en
Pages : 767
Book Description
The Science of Synthesis Editorial Board, together with the volume editors and authors, is constantly reviewing the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluating significant developments in synthetic methodology. Four annual volumes updating content across all categories ensure that you always have access to state-of-the-art synthetic methodology.
Publisher: Thieme
ISBN: 3131762713
Category : Science
Languages : en
Pages : 767
Book Description
The Science of Synthesis Editorial Board, together with the volume editors and authors, is constantly reviewing the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluating significant developments in synthetic methodology. Four annual volumes updating content across all categories ensure that you always have access to state-of-the-art synthetic methodology.
Multicomponent Reactions in Organic Synthesis
Author: Jieping Zhu
Publisher: John Wiley & Sons
ISBN: 3527332375
Category : Science
Languages : en
Pages : 512
Book Description
Comprehensive and up-to-date, this book focuses on the latest advances in the field, such as newly developed techniques, more environmentally benign processes, broadened scopes, and completely novel MCRs. In addition to carbene-promoted MCRs and frequently applied metal-catalyzed MCRs, it also covers recently developed catalytic enantioselective variants as well as MCR in drug discovery and for the synthesis of heterocyclic molecules and macrocycles. Edited by the leading experts and with a list of authors reading like a "who's who" in multicomponent reaction chemistry, this is definitely a must-have for every synthetic organic chemist as well as medicinal chemists working in academia and pharmaceutical companies.
Publisher: John Wiley & Sons
ISBN: 3527332375
Category : Science
Languages : en
Pages : 512
Book Description
Comprehensive and up-to-date, this book focuses on the latest advances in the field, such as newly developed techniques, more environmentally benign processes, broadened scopes, and completely novel MCRs. In addition to carbene-promoted MCRs and frequently applied metal-catalyzed MCRs, it also covers recently developed catalytic enantioselective variants as well as MCR in drug discovery and for the synthesis of heterocyclic molecules and macrocycles. Edited by the leading experts and with a list of authors reading like a "who's who" in multicomponent reaction chemistry, this is definitely a must-have for every synthetic organic chemist as well as medicinal chemists working in academia and pharmaceutical companies.
Science of Synthesis Knowledge Updates 2012 Vol. 2
Author: R. Alan Aitken
Publisher: Thieme
ISBN: 3131788313
Category : Science
Languages : en
Pages : 829
Book Description
The Science of Synthesis Editorial Board, together with the volume editors and authors, is constantly reviewing the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluating significant developments in synthetic methodology. Four annual volumes updating content across all categories ensure that you always have access to state-of-the-art synthetic methodology.
Publisher: Thieme
ISBN: 3131788313
Category : Science
Languages : en
Pages : 829
Book Description
The Science of Synthesis Editorial Board, together with the volume editors and authors, is constantly reviewing the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluating significant developments in synthetic methodology. Four annual volumes updating content across all categories ensure that you always have access to state-of-the-art synthetic methodology.
Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis
Author: E. Fernández
Publisher: Thieme
ISBN: 3132429732
Category : Science
Languages : en
Pages : 582
Book Description
The widespread use of organoboron compounds justifies the efforts devoted to their synthesis, as well as toward developing an understanding of their reactivity. The nature of the mono- or diboron species is of paramount importance in determining the reversible covalent binding properties of the boron atom with both nucleophiles and electrophiles. By wedding the rich chemical potential of organoboron compounds to the ubiquity of organic scaffolds, advanced borylation reactions have the potential to open unprecedented synthetic alternatives, and new knowledge in the field should encourage chemists to use organoboron compounds. In this volume, the main objective is to provide a collection of the most useful, practical, and reliable methods, reported mainly within the last decade, for boron activation and boron reactivity. The volume covers the main concepts of organoboron compounds and includes experimental procedures, enabling newcomers to the field the instant and reliable application of the new tools in synthesis. Rather than aiming for a comprehensive coverage, the most advanced solutions for challenging transformations are introduced. To this end, a team of pioneers and leaders in the field have been assembled who discuss both the practical and conceptual aspects of this rapidly growing field.
Publisher: Thieme
ISBN: 3132429732
Category : Science
Languages : en
Pages : 582
Book Description
The widespread use of organoboron compounds justifies the efforts devoted to their synthesis, as well as toward developing an understanding of their reactivity. The nature of the mono- or diboron species is of paramount importance in determining the reversible covalent binding properties of the boron atom with both nucleophiles and electrophiles. By wedding the rich chemical potential of organoboron compounds to the ubiquity of organic scaffolds, advanced borylation reactions have the potential to open unprecedented synthetic alternatives, and new knowledge in the field should encourage chemists to use organoboron compounds. In this volume, the main objective is to provide a collection of the most useful, practical, and reliable methods, reported mainly within the last decade, for boron activation and boron reactivity. The volume covers the main concepts of organoboron compounds and includes experimental procedures, enabling newcomers to the field the instant and reliable application of the new tools in synthesis. Rather than aiming for a comprehensive coverage, the most advanced solutions for challenging transformations are introduced. To this end, a team of pioneers and leaders in the field have been assembled who discuss both the practical and conceptual aspects of this rapidly growing field.
Science of Synthesis: Biocatalysis in Organic Synthesis Vol. 2
Author: Kurt Faber
Publisher: Thieme
ISBN: 3131766417
Category : Science
Languages : en
Pages : 1000
Book Description
The three Science of Synthesis volumes on "Biocatalysis in Organic Synthesis" present a broad contemporary overview on the state-of-the-art in enzymatic methods for asymmetric synthesis suitable for academics and industrial researchers working in the field of organic synthesis. The goal is to start a new wave of enthusiasm for biocatalysis in the broader community and to give an overview of the field. "Biocatalysis in Organic Synthesis" offers critical reviews of organic transformations by experts, including experimental procedures. The organization is based on the type of reaction performed under biocatalysis. Volume 2 covers reactions involving the formation of C-C bonds. Addition of carbon nucleophiles at C-O and C-N double bonds are reviewed, as are methods for the formation of C-C bonds at arenes and additions to C-C double bonds. Other chapters present transamination and reductive amination reactions, reduction of carbonyl compounds, and the uses of epoxides in biocatalysis.
Publisher: Thieme
ISBN: 3131766417
Category : Science
Languages : en
Pages : 1000
Book Description
The three Science of Synthesis volumes on "Biocatalysis in Organic Synthesis" present a broad contemporary overview on the state-of-the-art in enzymatic methods for asymmetric synthesis suitable for academics and industrial researchers working in the field of organic synthesis. The goal is to start a new wave of enthusiasm for biocatalysis in the broader community and to give an overview of the field. "Biocatalysis in Organic Synthesis" offers critical reviews of organic transformations by experts, including experimental procedures. The organization is based on the type of reaction performed under biocatalysis. Volume 2 covers reactions involving the formation of C-C bonds. Addition of carbon nucleophiles at C-O and C-N double bonds are reviewed, as are methods for the formation of C-C bonds at arenes and additions to C-C double bonds. Other chapters present transamination and reductive amination reactions, reduction of carbonyl compounds, and the uses of epoxides in biocatalysis.
Science of Synthesis Knowledge Updates 2011 Vol. 2
Author: Erick M. Carreira
Publisher: Thieme
ISBN: 3131787414
Category : Science
Languages : en
Pages : 884
Book Description
The Science of Synthesis Editorial Board, together with the volume editors and authors, is constantly reviewing the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluating significant developments in synthetic methodology. Four annual volumes updating content across all categories ensure that you always have access to state-of-the-art synthetic methodology.
Publisher: Thieme
ISBN: 3131787414
Category : Science
Languages : en
Pages : 884
Book Description
The Science of Synthesis Editorial Board, together with the volume editors and authors, is constantly reviewing the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluating significant developments in synthetic methodology. Four annual volumes updating content across all categories ensure that you always have access to state-of-the-art synthetic methodology.
Science of Synthesis: Catalytic Transformations via C-H Activation Vol. 2
Author: Jin-Quan Yu
Publisher: Thieme
ISBN: 3132057819
Category : Science
Languages : en
Pages : 755
Book Description
The reference work "Science of Synthesis: Catalytic Transformations via C-H Activation" covers the state of the art in C-H activation chemistry. Experts in the field present the best synthetic methods including typical or general experimental procedures. As such, this two volume set can serve as both a basis for the practical application of the techniques discussed, and as an educational resource to lay the foundations for future research. Volume 2 concerns the formation of C-C bonds by C-H activation of non-(het)arene substrates as well as C-H activation using special reagents or techniques. The formation of C-heteroatom bonds by predominantly arene C-H activation is also reviewed. For C-C bond formation, the material is subdivided into allylic, alkyl, and double C-H activation techniques, coupling using carbenes or radicals, and carbonylation or carboxylation processes.
Publisher: Thieme
ISBN: 3132057819
Category : Science
Languages : en
Pages : 755
Book Description
The reference work "Science of Synthesis: Catalytic Transformations via C-H Activation" covers the state of the art in C-H activation chemistry. Experts in the field present the best synthetic methods including typical or general experimental procedures. As such, this two volume set can serve as both a basis for the practical application of the techniques discussed, and as an educational resource to lay the foundations for future research. Volume 2 concerns the formation of C-C bonds by C-H activation of non-(het)arene substrates as well as C-H activation using special reagents or techniques. The formation of C-heteroatom bonds by predominantly arene C-H activation is also reviewed. For C-C bond formation, the material is subdivided into allylic, alkyl, and double C-H activation techniques, coupling using carbenes or radicals, and carbonylation or carboxylation processes.
Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis Vol. 2
Author: Steven Nolan
Publisher: Thieme
ISBN: 3132414034
Category : Science
Languages : en
Pages : 816
Book Description
The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. "Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis" presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.
Publisher: Thieme
ISBN: 3132414034
Category : Science
Languages : en
Pages : 816
Book Description
The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. "Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis" presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.