Laboratory Biorisk Management

Laboratory Biorisk Management PDF Author: Reynolds M. Salerno
Publisher: CRC Press
ISBN: 1498749747
Category : Medical
Languages : en
Pages : 198

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Book Description
Over the past two decades bioscience facilities worldwide have experienced multiple safety and security incidents, including many notable incidents at so-called "sophisticated facilities" in North America and Western Europe. This demonstrates that a system based solely on biosafety levels and security regulations may not be sufficient. Setting the stage for a substantively different approach for managing the risks of working with biological agents in laboratories, Laboratory Biorisk Management: Biosafety and Biosecurity introduces the concept of biorisk management—a new paradigm that encompasses both laboratory biosafety and biosecurity. The book also provides laboratory managers and directors with the information and technical tools needed for its implementation. The basis for this new paradigm is a three-pronged, multi-disciplinary model of assessment, mitigation, and performance (the AMP model). The application of the methodologies, criteria, and guidance outlined in the book helps to reduce the risk of laboratories becoming the sources of infectious disease outbreaks. This is a valuable resource for those seeking to embrace and implement biorisk management systems in their facilities and operations, including the biological research, clinical diagnostic, and production/manufacturing communities.

Laboratory Biorisk Management

Laboratory Biorisk Management PDF Author: Reynolds M. Salerno
Publisher: CRC Press
ISBN: 1498749747
Category : Medical
Languages : en
Pages : 198

Get Book Here

Book Description
Over the past two decades bioscience facilities worldwide have experienced multiple safety and security incidents, including many notable incidents at so-called "sophisticated facilities" in North America and Western Europe. This demonstrates that a system based solely on biosafety levels and security regulations may not be sufficient. Setting the stage for a substantively different approach for managing the risks of working with biological agents in laboratories, Laboratory Biorisk Management: Biosafety and Biosecurity introduces the concept of biorisk management—a new paradigm that encompasses both laboratory biosafety and biosecurity. The book also provides laboratory managers and directors with the information and technical tools needed for its implementation. The basis for this new paradigm is a three-pronged, multi-disciplinary model of assessment, mitigation, and performance (the AMP model). The application of the methodologies, criteria, and guidance outlined in the book helps to reduce the risk of laboratories becoming the sources of infectious disease outbreaks. This is a valuable resource for those seeking to embrace and implement biorisk management systems in their facilities and operations, including the biological research, clinical diagnostic, and production/manufacturing communities.

Sandia National Laboratories

Sandia National Laboratories PDF Author: Necah Stewart Furman
Publisher:
ISBN:
Category : History
Languages : en
Pages : 896

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Book Description


Biotechnology for Biofuel Production and Optimization

Biotechnology for Biofuel Production and Optimization PDF Author: Carrie A Eckert
Publisher: Elsevier
ISBN: 0081000537
Category : Science
Languages : en
Pages : 574

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Book Description
Biotechnology for Biofuel Production and Optimization is the compilation of current research findings that cover the entire process of biofuels production from manipulation of genes and pathways to organisms and renewable feedstocks for efficient biofuel production as well as different cultivation techniques and process scale-up considerations. This book captures recent breakthroughs in the interdisciplinary areas of systems and synthetic biology, metabolic engineering, and bioprocess engineering for renewable, cleaner sources of energy. - Describes state-of-the-art engineering of metabolic pathways for the production of a variety of fuel molecules - Discusses recent advances in synthetic biology and metabolic engineering for rational design, construction, evaluation of novel pathways and cell chassis - Covers genome engineering technologies to address complex biofuel-tolerant phenotypes for enhanced biofuel production in engineered chassis - Presents the use of novel microorganisms and expanded substrate utilization strategies for production of targeted fuel molecules - Explores biohybrid methods for harvesting bioenergy - Discusses bioreactor design and optimization of scale-up

The Art of Software Security Testing

The Art of Software Security Testing PDF Author: Chris Wysopal
Publisher: Pearson Education
ISBN: 0132715759
Category : Computers
Languages : en
Pages : 332

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Book Description
State-of-the-Art Software Security Testing: Expert, Up to Date, and Comprehensive The Art of Software Security Testing delivers in-depth, up-to-date, battle-tested techniques for anticipating and identifying software security problems before the “bad guys” do. Drawing on decades of experience in application and penetration testing, this book’s authors can help you transform your approach from mere “verification” to proactive “attack.” The authors begin by systematically reviewing the design and coding vulnerabilities that can arise in software, and offering realistic guidance in avoiding them. Next, they show you ways to customize software debugging tools to test the unique aspects of any program and then analyze the results to identify exploitable vulnerabilities. Coverage includes Tips on how to think the way software attackers think to strengthen your defense strategy Cost-effectively integrating security testing into your development lifecycle Using threat modeling to prioritize testing based on your top areas of risk Building testing labs for performing white-, grey-, and black-box software testing Choosing and using the right tools for each testing project Executing today’s leading attacks, from fault injection to buffer overflows Determining which flaws are most likely to be exploited by real-world attackers

Understanding and Managing Risk in Security Systems for the DOE Nuclear Weapons Complex

Understanding and Managing Risk in Security Systems for the DOE Nuclear Weapons Complex PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309208874
Category : Technology & Engineering
Languages : en
Pages : 30

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Book Description
A nuclear weapon or a significant quantity of special nuclear material (SNM) would be of great value to a terrorist or other adversary. It might have particular value if acquired from a U.S. facility-in addition to acquiring a highly destructive tool, the adversary would demonstrate an inability of the United States to protect its nuclear assets. The United States expends considerable resources toward maintaining effective security at facilities that house its nuclear assets. However, particularly in a budget-constrained environment, it is essential that these assets are also secured efficiently, meaning at reasonable cost and imposing minimal burdens on the primary missions of the organizations that operate U.S. nuclear facilities. It is in this context that the U.S. Congress directed the National Nuclear Security Administration (NNSA)-a semi-autonomous agency in the U.S. Department of Energy (DOE) responsible for securing nuclear weapons and significant quantities of SNM-asked the National Academies for advice on augmenting its security approach, particularly on the applicability of quantitative and other risk-based approaches for securing its facilities. In carrying out its charge, the committee has focused on what actions NNSA could take to make its security approach more effective and efficient. The committee concluded that the solution to balancing cost, security, and operations at facilities in the nuclear weapons complex is not to assess security risks more quantitatively or more precisely. This is primarily because there is no comprehensive analytical basis for defining the attack strategies that a malicious, creative, and deliberate adversary might employ or the probabilities associated with them. However, using structured thinking processes and techniques to characterize security risk could improve NNSA's understanding of security vulnerabilities and guide more effective resource allocation.

Shock Waves @ Marseille I

Shock Waves @ Marseille I PDF Author: Raymond Brun
Publisher: Springer Science & Business Media
ISBN: 3642788297
Category : Science
Languages : en
Pages : 497

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Book Description
Recently, there have been significant advances in the fields of high-enthalpy hypersonic flows, high-temperature gas physics, and chemistry shock propagation in various media, industrial and medical applications of shock waves, and shock-tube technology. This series contains all the papers and lectures of the 19th International Symposium on Shock Waves held in Marseille in 1993. They are published in four topical volumes, each containing papers on related topics, and preceded by an overview written by a leading international expert. The volumes may be purchased independently.

Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors

Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309379210
Category : Science
Languages : en
Pages : 205

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Book Description
The continued presence of highly enriched uranium (HEU) in civilian installations such as research reactors poses a threat to national and international security. Minimization, and ultimately elimination, of HEU in civilian research reactors worldwide has been a goal of U.S. policy and programs since 1978. Today, 74 civilian research reactors around the world, including 8 in the United States, use or are planning to use HEU fuel. Since the last National Academies of Sciences, Engineering, and Medicine report on this topic in 2009, 28 reactors have been either shut down or converted from HEU to low enriched uranium fuel. Despite this progress, the large number of remaining HEU-fueled reactors demonstrates that an HEU minimization program continues to be needed on a worldwide scale. Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors assesses the status of and progress toward eliminating the worldwide use of HEU fuel in civilian research and test reactors.

Sandia Mountain Hiking Guide

Sandia Mountain Hiking Guide PDF Author: Michael Elliott Coltrin
Publisher: UNM Press
ISBN: 9780826336613
Category : Sports & Recreation
Languages : en
Pages : 196

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Book Description
This guide to fifty-seven hiking trails in New Mexico's Sandia Mountains includes twenty-five contour maps and one large four-color pull-out map on water-resistant paper.

Laboratory Biosecurity Handbook

Laboratory Biosecurity Handbook PDF Author: Reynolds M. Salerno
Publisher: CRC Press
ISBN: 1420006207
Category : Computers
Languages : en
Pages : 210

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Book Description
By achieving a delicate balance between systems and practices, proper laboratory biosecurity reduces the risk of legitimate bioscience facilities becoming sources of pathogens and toxins for malicious use. Effective design and implementation of laboratory biosecurity depends on cooperation among individuals from diverse communities, including scien

Laser Microfabrication

Laser Microfabrication PDF Author: Daniel J. Ehrlich
Publisher: Elsevier
ISBN: 0080918026
Category : Technology & Engineering
Languages : en
Pages : 602

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Book Description
This book reviews the solid core of fundamental scientific knowledge on laser-stimulated surface chemistry that has accumulated over the past few years. It provides a useful overview for the student and interested non-expert as well as essential reference data (photodissociation cross sections, thermochemical constants, etc.) for the active researcher.