Safety Concerns for Herbal Drugs

Safety Concerns for Herbal Drugs PDF Author: Divya Vohora
Publisher: CRC Press
ISBN: 1482256622
Category : Health & Fitness
Languages : en
Pages : 160

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Book Description
Are herbal drugs totally devoid of adverse effects when used alone, as herbal formulations, or in concurrent use with modern medicines? Safety Concerns for Herbal Drugs examines that question and others like it to give you the information you need to judge for yourself the balance between the risks and benefits associated with the therapeutic use of medicinal plants. It stands out from other books by directing your attention to the aspects of safety and toxicity. The authors venture into the relatively unexplored (or deliberately hidden) side of the picture. They present a survey of approximately 1500 medicinal plants and herbal products, 59 global (from 27 countries) and 75 Indian examples of toxic and adverse effects and drug interactions. Additionally, they present the current status of regulatory laws and their enforcement in 73 countries to support their contention that such laws and enforcement are inadequate, and that herbal drugs are unscientifically being promoted as totally safe. To give you the full picture, the authors go on to examine such issues as danger from large-scale misuse and abuse, self-prescription, substitution, adulteration, concurrent use with modern medicines, hazardous but avoidable drug interactions, risk groups, and present status of drug regulations.

Safety Concerns for Herbal Drugs

Safety Concerns for Herbal Drugs PDF Author: Divya Vohora
Publisher: CRC Press
ISBN: 1482256622
Category : Health & Fitness
Languages : en
Pages : 160

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Book Description
Are herbal drugs totally devoid of adverse effects when used alone, as herbal formulations, or in concurrent use with modern medicines? Safety Concerns for Herbal Drugs examines that question and others like it to give you the information you need to judge for yourself the balance between the risks and benefits associated with the therapeutic use of medicinal plants. It stands out from other books by directing your attention to the aspects of safety and toxicity. The authors venture into the relatively unexplored (or deliberately hidden) side of the picture. They present a survey of approximately 1500 medicinal plants and herbal products, 59 global (from 27 countries) and 75 Indian examples of toxic and adverse effects and drug interactions. Additionally, they present the current status of regulatory laws and their enforcement in 73 countries to support their contention that such laws and enforcement are inadequate, and that herbal drugs are unscientifically being promoted as totally safe. To give you the full picture, the authors go on to examine such issues as danger from large-scale misuse and abuse, self-prescription, substitution, adulteration, concurrent use with modern medicines, hazardous but avoidable drug interactions, risk groups, and present status of drug regulations.

Safety Concerns for Herbal Drugs

Safety Concerns for Herbal Drugs PDF Author: Mikolaj Tosto
Publisher:
ISBN: 9781681176963
Category :
Languages : en
Pages : 320

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Book Description
In many countries around the globe, herbal supplements, tisanes and vegetable products, together with traditional Chinese medicines, are mostly unregulated and their content is not registered, examined or certified. Subsequently, potent plant toxins including dehydropyrrolizidine alkaloids and other forthcoming carcinogens can contaminate these products. As herbal and food supplement producers are left to their own means to determine the safety and purity of their products before marketing, disturbingly often good marketing practices currently in place are ignored and content is largely undocumented. As herbal medicines are used by increasing numbers of people, pharmacists must be knowledgeable about their safety. This requires appreciation of the magnitude of use, as well as regulations under which the products are marketed that may affect their safety. Unexpected effects of many popular herbal products are described in the text. Thus the pharmacist''s role in ensuring protection of the consumer continues to grow. Hence, more work is needed to educate consumers of the potential risk and require the industry to be more responsible to verify the content and insure the safety of their products. Safety Concerns for Herbal Drugs inspects the information required to review for you the balance between the risks and benefits related with the therapeutic use of medicinal plants. It focuses attention on the safety and toxicity aspects of herbal products. It also presents an overview of some of the most commonly used herbal products, including important clinical considerations in the use of these products. Herbal products and dietary supplements are widely available in supermarkets and other retail outlets, as well as by mail order. In fact, only a small percentage of these products are actually sold in pharmacies. Many patients believe they derive health benefits from these herbal preparations, yet some remain skeptical and may seek advice from health professionals prior to use. Thus, it is important for all health professionals, to be informed about available products and to be aware of any potential problems associated with their use. This text should be of valuable for medical students, health professionals, researchers as well as practitioners.In many countries around the globe, herbal supplements, tisanes and vegetable products, together with traditional Chinese medicines, are mostly unregulated and their content is not registered, examined or certified. Subsequently, potent plant toxins including dehydropyrrolizidine alkaloids and other forthcoming carcinogens can contaminate these products. As herbal and food supplement producers are left to their own means to determine the safety and purity of their products before marketing, disturbingly often good marketing practices currently in place are ignored and content is largely undocumented. As herbal medicines are used by increasing numbers of people, pharmacists must be knowledgeable about their safety. This requires appreciation of the magnitude of use, as well as regulations under which the products are marketed that may affect their safety. Unexpected effects of many popular herbal products are described in the text. Thus the pharmacist''s role in ensuring protection of the consumer continues to grow. Hence, more work is needed to educate consumers of the potential risk and require the industry to be more responsible to verify the content and insure the safety of their products. Safety Concerns for Herbal Drugs inspects the information required to review for you the balance between the risks and benefits related with the therapeutic use of medicinal plants. It focuses attention on the safety and toxicity aspects of herbal products. It also presents an overview of some of the most commonly used herbal products, including important clinical considerations in the use of these products. Herbal products and dietary supplements are widely available in supermarkets and other retail outlets, as well as by mail order. In fact, only a small percentage of these products are actually sold in pharmacies. Many patients believe they derive health benefits from these herbal preparations, yet some remain skeptical and may seek advice from health professionals prior to use. Thus, it is important for all health professionals, to be informed about available products and to be aware of any potential problems associated with their use. This text should be of valuable for medical students, health professionals, researchers as well as practitioners.

The Essential Guide to Herbal Safety

The Essential Guide to Herbal Safety PDF Author: Simon Y Mills
Publisher: Elsevier Health Sciences
ISBN: 0443071713
Category : Medical
Languages : en
Pages : 704

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Book Description
Winner of American Botanical Council's 2005 James A. Duke Botanical Literature Award, the Essential Guide to Herbal Safety offers a balanced and objective perspective on the principles of herbal medicine safety as well as the complex challenges relating to self-prescribed or professionally prescribed herbal medications and supplements. With contributions from leading international practitioners and authorities, it contains comprehensive reviews, in monograph format, of the published safety data for 125 common herbs. You'll also find coverage of issues of quality, interactions, adverse reactions, toxicity, allergy, contact sensitivity, and idiosyncratic reactions. Provides the most current information on safety issues in herbal medicine. Presents authoritative and credible safety information from two experienced herbal practitioners. Combines theoretical chapters with 125 well-researched monographs, making it the most thorough and comprehensive text on the market for herbal safety in practice. Provides clear information using the most current evidence-based reviews, covering factors that influence herb safety, including the negative placebo effects (nocebo), various types of unpredictable effects, the basis for interactions between herbs and drugs, and quality issues. Uses an established grading system for assessing safety in pregnancy and lactation that is realistic and appropriate to herb use. Thoroughly critiques the dominant misinformation in the media and medical journals on herb safety issues. Contains 83 documented case studies on hepatoxicity and the effects in relation to kava. Kava safety is a hot topic. Includes two useful appendices detailing herbal references for pregnancy and lactation considerations.

Herbal Medicine

Herbal Medicine PDF Author: Iris F. F. Benzie
Publisher: CRC Press
ISBN: 1439807167
Category : Health & Fitness
Languages : en
Pages : 500

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Book Description
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Drug-Induced Liver Disease

Drug-Induced Liver Disease PDF Author: Neil Kaplowitz
Publisher: CRC Press
ISBN: 0203909127
Category : Medical
Languages : en
Pages : 784

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Book Description
Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.

Adverse Effects of Herbal Drugs

Adverse Effects of Herbal Drugs PDF Author:
Publisher: Springer Science & Business Media
ISBN: 364260367X
Category : Medical
Languages : en
Pages : 380

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Book Description
This book series gives a comprehensive overview of the adverse effects of botanical medicines. It provides introductory information on Botany, Chemistry, Pharmacology and Uses, followed by an Adverse Reaction Profile subdivided according to organ and function. The third contribution to the series gives important information about eighteen specific medicinal herbs and important plant constituents. The herbs and constituents have been selected for several reasons, such as a prominent place in phytotherapy, clinical expectations about therapeutic potential and recent concern about a serious adverse reaction. The World Health Organization Regional Office for Europe (Copenhagen) has supported the book in the form of an acknowledgement that has been prepared by this Office.

Herbal Drugs: Ethnomedicine to Modern Medicine

Herbal Drugs: Ethnomedicine to Modern Medicine PDF Author: Kishan Gopal Ramawat
Publisher: Springer Science & Business Media
ISBN: 3540791167
Category : Science
Languages : en
Pages : 414

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Book Description
Considerable progress has been made in our healthcare system, in particular with respect to sensitive diagnostic tools, reagents and very effective and precise drugs. On the other hand, high-throughput screening technology can screen vast numbers of compounds against an array of targets in a very short time, and leads thus - tained can be further explored. In developing countries, the exploding population exerts pressure not only on natural resources but also on the human population - self, whose members strive to become successful and advance in society. This leads to increased blood pressure, anxiety, obesity-associated lipid disorders, cardiov- cular diseases and diabetes. Most of these diseases result in disturbed family life, including sexual behaviour. Despite technological developments, herbal drugs still occupy a preferential place in a majority of the population in the Third World and terminal patients in the West. Herbal drugs, in addition to being cost effective and easily accessible, have been used since time immemorial and have passed the test of time without having any side effects. The multitarget effects of herbs (holistic approaches) are the fun- mental basis of their utilization. This approach is already used in traditional systems of medicine like Ayurveda, which has become more popular in the West in recent years. However, the integration of modern science with traditional uses of herbal drugs is of the utmost importance if ones wishes to use ancient knowledge for the betterment of humanity.

American Herbal Products Association’s Botanical Safety Handbook, Second Edition

American Herbal Products Association’s Botanical Safety Handbook, Second Edition PDF Author: Zoë Gardner
Publisher: CRC Press
ISBN: 1466516941
Category : Health & Fitness
Languages : en
Pages : 1073

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Book Description
Access to accurate, evidence-based, and clinically relevant information is essential to anyone who uses or recommends herbal products. With input from some of the most respected experts in herbal and integrative medicine, this completely revised edition of the American Herbal Products Association’s Botanical Safety Handbook reviews both traditional knowledge and contemporary research on herbs to provide an authoritative resource on botanical safety. The book covers more than 500 species of herbs and provides a holistic understanding of safety through data compiled from clinical trials, pharmacological and toxicological studies, medical case reports, and historical texts. For each species, a brief safety summary is provided for quick reference, along with a detailed review of the literature. Easily understood classification systems are used to indicate the safety of each listed species and the potential for the species to interact with drugs. Enhancements to the Second Edition include: Classification of each herb with both a safety rating and a drug interaction rating More references listed for each individual herb, vetted for accuracy Specific information on adverse events reported in clinical trials or case reports Safety-related pharmacology and pharmacokinetics of each herb, including drug interactions Additional information on the use of herbs by pregnant or lactating women Toxicological studies and data on toxic compounds Representing the core of the botanical trade and comprising the finest growers, processors, manufacturers, and marketers of herbal products, the mission of the AHPA is to promote the responsible commerce of herbal products. The American Herbal Products Association Botanical Safety Handbook, Second Edition ensures that this vision is attained. The book will be a valuable reference for product manufacturers, healthcare practitioners, regulatory agencies, researchers, and consumers of herbal products.

WHO Guidelines on Safety Monitoring of Herbal Medicines in Pharmacovigilance Systems

WHO Guidelines on Safety Monitoring of Herbal Medicines in Pharmacovigilance Systems PDF Author: World Health Organization
Publisher:
ISBN: 9789241592215
Category : Drug monitoring
Languages : en
Pages : 18

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Book Description
Safety is a fundamental principle in the privision of herbal medicines and herbal products for health care and a critical component of quality control. These guidelines provide practical technical guidance for monitoring the safety of herbal medicines with pharmacovigilance systems.

Natural Medicines

Natural Medicines PDF Author: Dilip Ghosh
Publisher: CRC Press
ISBN: 1351741357
Category : Medical
Languages : en
Pages : 632

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Book Description
Globally, natural medicine has been considered as an important alternative to modern allopathic medicine. Although natural medicines are popular in society, only limited medicinal herbs have been scientifically evaluated for their potential in medical treatment. This book connects various aspects of the complex journey from traditional medicine to modern medicine. It provides information on topics including global regulations and regulatory hurdles, diverse nutritional challenges and potential health benefits, novel food innovations especially seed-to-clinic approaches, and future trends. FEATURES • Provides information on sustainable use of natural products in the development of new drugs and clinically validated herbal remedies • Discusses issues on evaluation and clinical aspects of herbal medicine, promotion and development, safety evaluation, metabolite profiling, biomarker analysis, formulation, and stability testing • Describes traditional uses of natural medicine through identification, isolation and structural characterization of their active components • Elucidates mechanisms of biological action, adverse effects and identification of their molecular targets of natural medicine • Multidisciplinary appeal including chemistry, pharmacology, pharmacognosy and cell and molecular biology, as well as integration with clinical medicine This book serves as an essential guide for individuals researching natural medicines, and industry employees in areas including drug development, pharmacology, natural products chemistry, clinical efficacy, ethnopharmacology, pharmacognosy, phytotherapy, phyto-technology and herbal science.