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Author: Daniel Reid Kuespert
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110444437
Category : Technology & Engineering
Languages : en
Pages : 282
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Book Description
Research Laboratory Safety explains the most important prerequisite when working in a laboratory: Knowing the potential hazards of equipment and the chemical materials to be employed. Students learn how to assess and control risks in a research laboratory and to identify a possible danger. An approach on the hazard classes such as physical, chemical, biological and radiation hazards is given and exercises to each class prepare for exams.
Author: Daniel Reid Kuespert
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110444437
Category : Technology & Engineering
Languages : en
Pages : 282
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Book Description
Research Laboratory Safety explains the most important prerequisite when working in a laboratory: Knowing the potential hazards of equipment and the chemical materials to be employed. Students learn how to assess and control risks in a research laboratory and to identify a possible danger. An approach on the hazard classes such as physical, chemical, biological and radiation hazards is given and exercises to each class prepare for exams.
Author: National Research Council
Publisher: National Academies Press
ISBN: 030918651X
Category : Medical
Languages : en
Pages : 163
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Book Description
Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.
Author: Swapan Basu
Publisher: Academic Press
ISBN: 0128038217
Category : Technology & Engineering
Languages : en
Pages : 1064
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Book Description
Plant Hazard Analysis and Safety Instrumentation Systems is the first book to combine coverage of these two integral aspects of running a chemical processing plant. It helps engineers from various disciplines learn how various analysis techniques, international standards, and instrumentation and controls provide layers of protection for basic process control systems, and how, as a result, overall system reliability, availability, dependability, and maintainability can be increased. This step-by-step guide takes readers through the development of safety instrumented systems, also including discussions on cost impact, basics of statistics, and reliability. Swapan Basu brings more than 35 years of industrial experience to this book, using practical examples to demonstrate concepts. Basu links between the SIS requirements and process hazard analysis in order to complete SIS lifecycle implementation and covers safety analysis and realization in control systems, with up-to-date descriptions of modern concepts, such as SIL, SIS, and Fault Tolerance to name a few. In addition, the book addresses security issues that are particularly important for the programmable systems in modern plants, and discusses, at length, hazardous atmospheres and their impact on electrical enclosures and the use of IS circuits. - Helps the reader identify which hazard analysis method is the most appropriate (covers ALARP, HAZOP, FMEA, LOPA) - Provides tactics on how to implement standards, such as IEC 61508/61511 and ANSI/ISA 84 - Presents information on how to conduct safety analysis and realization in control systems and safety instrumentation
Author: Gianni Petrangeli
Publisher: Elsevier
ISBN: 008046078X
Category : Technology & Engineering
Languages : en
Pages : 447
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Book Description
Nuclear Safety provides the methods and data needed to evaluate and manage the safety of nuclear facilities and related processes using risk-based safety analysis, and provides readers with the techniques to assess the consequences of radioactive releases. The book covers relevant international and regional safety criteria (US, IAEA, EUR, PUN, URD, INI). The contents deal with each of the critical components of a nuclear plant, and provide an analysis of the risks arising from a variety of sources, including earthquakes, tornadoes, external impact and human factors. It also deals with the safety of underground nuclear testing and the handling of radioactive waste. - Covers all plant components and potential sources of risk including human, technical and natural factors. - Brings together information on nuclear safety for which the reader would previously have to consult many different and expensive sources. - Provides international design and safety criteria and an overview of regulatory regimes.
Author: Darren J. Torbic
Publisher:
ISBN: 9780309673556
Category : Construction projects
Languages : en
Pages : 0
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Book Description
Traditional approaches to safety have focused on identifying high-crash locations and implementing projects to address predominant concerns at these locations. The systemic approach to safety is a method of safety management that typically involves lower unit cost safety improvements that are widely implemented based on high risk factors. The TRB National Cooperative Highway Research Program's NCHRP Research Report 955: Guide for Quantitative Approaches to Systemic Safety Analysis provides guidance to state departments of transportation (DOTs) and other transportation agencies on how to apply a systemic safety management approach for identifying safety improvement projects. Material associated with the report includes NCHRP Web-Only Document 285: Developing a Guide for Quantitative Approaches to Systemic Safety Analysis and a PowerPoint of the summary of project findings and future research needs.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309068371
Category : Medical
Languages : en
Pages : 312
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Book Description
Experts estimate that as many as 98,000 people die in any given year from medical errors that occur in hospitals. That's more than die from motor vehicle accidents, breast cancer, or AIDSâ€"three causes that receive far more public attention. Indeed, more people die annually from medication errors than from workplace injuries. Add the financial cost to the human tragedy, and medical error easily rises to the top ranks of urgent, widespread public problems. To Err Is Human breaks the silence that has surrounded medical errors and their consequenceâ€"but not by pointing fingers at caring health care professionals who make honest mistakes. After all, to err is human. Instead, this book sets forth a national agendaâ€"with state and local implicationsâ€"for reducing medical errors and improving patient safety through the design of a safer health system. This volume reveals the often startling statistics of medical error and the disparity between the incidence of error and public perception of it, given many patients' expectations that the medical profession always performs perfectly. A careful examination is made of how the surrounding forces of legislation, regulation, and market activity influence the quality of care provided by health care organizations and then looks at their handling of medical mistakes. Using a detailed case study, the book reviews the current understanding of why these mistakes happen. A key theme is that legitimate liability concerns discourage reporting of errorsâ€"which begs the question, "How can we learn from our mistakes?" Balancing regulatory versus market-based initiatives and public versus private efforts, the Institute of Medicine presents wide-ranging recommendations for improving patient safety, in the areas of leadership, improved data collection and analysis, and development of effective systems at the level of direct patient care. To Err Is Human asserts that the problem is not bad people in health careâ€"it is that good people are working in bad systems that need to be made safer. Comprehensive and straightforward, this book offers a clear prescription for raising the level of patient safety in American health care. It also explains how patients themselves can influence the quality of care that they receive once they check into the hospital. This book will be vitally important to federal, state, and local health policy makers and regulators, health professional licensing officials, hospital administrators, medical educators and students, health caregivers, health journalists, patient advocatesâ€"as well as patients themselves. First in a series of publications from the Quality of Health Care in America, a project initiated by the Institute of Medicine
Author: Marko Cepin
Publisher: CRC Press
ISBN: 1351809725
Category : Technology & Engineering
Languages : en
Pages : 6847
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Book Description
Safety and Reliability – Theory and Applications contains the contributions presented at the 27th European Safety and Reliability Conference (ESREL 2017, Portorož, Slovenia, June 18-22, 2017). The book covers a wide range of topics, including: • Accident and Incident modelling • Economic Analysis in Risk Management • Foundational Issues in Risk Assessment and Management • Human Factors and Human Reliability • Maintenance Modeling and Applications • Mathematical Methods in Reliability and Safety • Prognostics and System Health Management • Resilience Engineering • Risk Assessment • Risk Management • Simulation for Safety and Reliability Analysis • Structural Reliability • System Reliability, and • Uncertainty Analysis. Selected special sessions include contributions on: the Marie Skłodowska-Curie innovative training network in structural safety; risk approaches in insurance and fi nance sectors; dynamic reliability and probabilistic safety assessment; Bayesian and statistical methods, reliability data and testing; oganizational factors and safety culture; software reliability and safety; probabilistic methods applied to power systems; socio-technical-economic systems; advanced safety assessment methodologies: extended Probabilistic Safety Assessment; reliability; availability; maintainability and safety in railways: theory & practice; big data risk analysis and management, and model-based reliability and safety engineering. Safety and Reliability – Theory and Applications will be of interest to professionals and academics working in a wide range of industrial and governmental sectors including: Aeronautics and Aerospace, Automotive Engineering, Civil Engineering, Electrical and Electronic Engineering, Energy Production and Distribution, Environmental Engineering, Information Technology and Telecommunications, Critical Infrastructures, Insurance and Finance, Manufacturing, Marine Industry, Mechanical Engineering, Natural Hazards, Nuclear Engineering, Offshore Oil and Gas, Security and Protection, Transportation, and Policy Making.
Author: Ton J. Cleophas
Publisher: Springer Science & Business Media
ISBN: 1402095236
Category : Mathematics
Languages : en
Pages : 550
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Book Description
In clinical medicine appropriate statistics has become indispensable to evaluate treatment effects. Randomized controlled trials are currently the only trials that truly provide evidence-based medicine. Evidence based medicine has become crucial to optimal treatment of patients. We can define randomized controlled trials by using Christopher J. Bulpitt’s definition “a carefully and ethically designed experiment which includes the provision of adequate and appropriate controls by a process of randomization, so that precisely framed questions can be answered”. The answers given by randomized controlled trials constitute at present the way how patients should be clinically managed. In the setup of such randomized trial one of the most important issues is the statistical basis. The randomized trial will never work when the statistical grounds and analyses have not been clearly defined beforehand. All endpoints should be clearly defined in order to perform appropriate power calculations. Based on these power calculations the exact number of available patients can be calculated in order to have a sufficient quantity of individuals to have the predefined questions answered. Therefore, every clinical physician should be capable to understand the statistical basis of well performed clinical trials. It is therefore a great pleasure that Drs. T. J. Cleophas, A. H. Zwinderman, and T. F. Cleophas have published a book on statistical analysis of clinical trials. The book entitled “Statistics Applied to Clinical Trials” is clearly written and makes complex issues in statistical analysis transparant.
Author: R. H. S. Winterton
Publisher: Elsevier
ISBN: 1483145247
Category : Technology & Engineering
Languages : en
Pages : 206
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Book Description
Thermal Design of Nuclear Reactors
Author: Frank Crawley
Publisher: Elsevier
ISBN: 0128035803
Category : Business & Economics
Languages : en
Pages : 173
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Book Description
HAZOP: Guide to Best Practice, 3rd Edition describes and illustrates the HAZOP study method, highlighting a variety of proven uses and approaches. This updated edition brings additional experience with which to assist the reader in delivering optimum safety and efficiency of performance of the HAZOP team. HAZOP is the most widely-used technique in the process industries for the identification of hazards and the planning of safety measures. This book explains how to implement HAZOP techniques in new facilities and apply it to existing facilities. The content covers many of the possible applications of HAZOP and takes you through all the stages of a study. This simple, easily digestible book is a favorite in the chemical and process industries. - A concise and clear guide to the do's and don'ts in HAZOP - New edition brings additional experience to help you deliver optimum safety and efficiency of performance. - Updated material includes a section on HAZOP study of a procedure with a detailed example, new sections on pre-meeting with the client auditing a study, human factors and linking HAZOP study to LOPA. A section on start-up and shutdown has been added to the chapter on specific applications of HAZOP.
