Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters

Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters PDF Author: M. Morad
Publisher: Springer Science & Business Media
ISBN: 9401139903
Category : Medical
Languages : en
Pages : 586

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Book Description
Knowledge of cardiac ion channels and transporters has advanced remarkably in the last two decades with the development of patch-clamp and molecular biological techniques. This textbook offers a comprehensive overview of structures and functions of ion channels and transporters in the heart. Readers are first introduced to the molecular biology and electrophysiology of all the important ion channels. After discussing their developmental changes, the pharmacology and pathophysiology of clinically-relevant ion channels are reviewed. Molecular aspects of the cardiac excitation-contraction coupling and intracellular Ca2+ regulation by ion transporters are also described. The book will be useful to electrophysiologists, cardiac physiologists and pharmacologists, and molecular biologists interested in ion channels at all levels. For research specialists, the book will provide a perspective of the field. The book can be used as a reference source for working scientists in the fields of ion channels, biophysics, cardiac electrophysiology, and pharmacology. It is aimed at graduate and medical students, designed for use as a textbook for graduate and medical courses.

Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters

Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters PDF Author: M. Morad
Publisher: Springer Science & Business Media
ISBN: 9401139903
Category : Medical
Languages : en
Pages : 586

Get Book

Book Description
Knowledge of cardiac ion channels and transporters has advanced remarkably in the last two decades with the development of patch-clamp and molecular biological techniques. This textbook offers a comprehensive overview of structures and functions of ion channels and transporters in the heart. Readers are first introduced to the molecular biology and electrophysiology of all the important ion channels. After discussing their developmental changes, the pharmacology and pathophysiology of clinically-relevant ion channels are reviewed. Molecular aspects of the cardiac excitation-contraction coupling and intracellular Ca2+ regulation by ion transporters are also described. The book will be useful to electrophysiologists, cardiac physiologists and pharmacologists, and molecular biologists interested in ion channels at all levels. For research specialists, the book will provide a perspective of the field. The book can be used as a reference source for working scientists in the fields of ion channels, biophysics, cardiac electrophysiology, and pharmacology. It is aimed at graduate and medical students, designed for use as a textbook for graduate and medical courses.

The Role of Neurotransmitters in Brain Injury

The Role of Neurotransmitters in Brain Injury PDF Author: W.D. Dietrich
Publisher: Springer Science & Business Media
ISBN: 1461534526
Category : Science
Languages : en
Pages : 375

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Book Description
Neuroscientists from various disciplines have given extraordinary attention to the role of neurotransmitters in the field of neuronal injury. This volume summarizes the original oral and poster contributions which were presented at the symposium, "The Role of Neurotransmitters in Brain Injury," in Key West, Florida, between June 7-9, 1991. This symposium was the official Satellite of Brain-91, the Fifteenth International Symposium on Cerebral Blood Flow and Metabolism, held in Miami the previous week. The two principal goals of the Key West satellite meeting were to document recent progress and, more importantly, to explore future directions for investigative studies of the role of neurotransmitters in brain injury. To achieve these goals we assembled participants from diverse scientific fields and specialties who brought their collective expertise to discussions on the importance of neurotransmitters in neuronal and vascular injury following brain ischemia, trauma, and epilepsy. Their contributions are reflected in this volume. An important section of this volume is devoted to the role of glutamate and glutamatergic receptors in the development of ischemic neuronal damage. Topics covered include the mechanisms of glutamate and other excitatory amino acids, and the role of underlying injury-induced release different glutamatergic receptors in brain injury, including the NMDA and the non-NMDA receptors. The involvement of other neurotransmitters in the process of ischemic brain injury is well established.

The Role of Phytoconstitutents in Health Care

The Role of Phytoconstitutents in Health Care PDF Author: Megh R. Goyal
Publisher: CRC Press
ISBN: 1000008363
Category : Technology & Engineering
Languages : en
Pages : 239

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Book Description
This informative volume provides new insights with scientific evidence on the uses of medicinal plants in the treatment of certain diseases. It reviews various therapies with herbal phytoconstituents for certain types of disorders, modes of action, and pharmacological screening. It focuses on potential benefits of herbal extracts and bioactive compounds for human health care, provides a comparative phytoconstituent analysis of selected medicinal plants using GCMS/FTIR techniques, and discusses the role of herbal medicines in female genital infections. It goes on to look at the health-boosting properties of cabbage and the functional properties of milk yam (Ipomoea digitata L.).

Diasporic Na(rra)tions

Diasporic Na(rra)tions PDF Author: Hanadi Al-Samman
Publisher:
ISBN:
Category : Arabic literature
Languages : en
Pages : 578

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Book Description


Greek Literature in the Roman Period and in Late Antiquity

Greek Literature in the Roman Period and in Late Antiquity PDF Author: Gregory Nagy
Publisher: Routledge
ISBN: 1136065865
Category : Literary Criticism
Languages : en
Pages : 350

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Book Description
First published in 2002. Routledge is an imprint of Taylor & Francis, an informa company.

Diastology E-Book

Diastology E-Book PDF Author: Allan L. Klein
Publisher: Elsevier Health Sciences
ISBN: 1437711006
Category : Medical
Languages : en
Pages : 473

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Book Description
This reference thoroughly equips you to successfully diagnose and manage even the most complex incidences of diastolic heart failure and their comorbidities. It examines the basic mechanisms of this condition through discussions of both cellular and anatomic causes; guides you through non-invasive techniques for diagnosis, including echocardiography, cardiac CT, and MRI; and provides expert advice on pharmacologic management. Covers the basic mechanisms of diastolic heart problems from both cellular and anatomic perspectives. Chapters covering modalities helpful in assessment of diastolic function such as: echocardiography, cardiac MRI, radionuclide ventriculography, and invasive hemodynamic measurements. Features in-depth assessments of all diagnostic methods for diastolic heart failure, including rationales for their use. Examines contributing conditions that play a role in diastolic heart failure and offers guidance on their management. Offers pharmacologic strategies for multiple problem management.

Role of Giant Corporations

Role of Giant Corporations PDF Author: United States. Congress. Senate. Select Committee on Small Business. Subcommittee on Monopoly
Publisher:
ISBN:
Category : Antitrust law
Languages : en
Pages : 496

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Book Description


Pain

Pain PDF Author: Fernando Cervero
Publisher: Newnes
ISBN: 0444519017
Category : Medical
Languages : en
Pages : 954

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Book Description
This volume provides a comprehensive accounting of pain and its relation to neurology. It is dedicated entirely to the mechanisms and clinical aspects of the subject, and provides a wealth of information on the latest neurobiological and clinical data surrounding the topic. From discussions of the physiology and pathology of the pain pathways from signaling, via spinal cord and supraspinal processing to endogenous pain modulation, users will gain an invaluable reference that provides a new understanding of pain related topics, including cytokines, sex differences, and the autonomic nervous system. Practicing clinicians, internists, surgeons, and those in the fields of psychiatry and gerontology will gain a greater understanding of this challenging topic with chapters that deal extensively with peripheral and central pain conditions, including specific disorders such as fibromyalgia, whiplash, psychiatric diseases, dementia, and even cancer. In addition, treatments for neuropathic pain are also thoroughly presented and discussed. * A comprehensive guide to the topic of pain and its relation to neurology * Invaluable information on specific topics of interest, including discussions of pain and its implications for related diseases and conditions such as fibromyalgia, whiplash, and even psychiatric disorders * Treatment protocols for neuropathic pain and patient care

Role Reversal

Role Reversal PDF Author: Anne C. Richard
Publisher: Center for Transatlantic Relations Sais
ISBN:
Category : Nature
Languages : en
Pages : 104

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Book Description
After Hurricane Katrina hit the Gulf Coast of the United States on the morning of August 29, 2005, offers of help from other countries poured in on the US Government. Not used to being a recipient of foreign aid, the federal government replied slowly and with mixed signals. This monograph tells the story of these foreign contributions and the U.S. response. Lessons from this experience suggest that plans for a vetting mechanism should be drawn up now so that it is widely understood before the next large-scale crisis hits. In addition, the international community should adopt a uniform list of goods for stockpiling and use in a crisis, and should meet to reach agreement on the best ways to respond to crises. Effective crisis response is an important part of national security.

RNA and RNA Modification in the Pathogenesis, Diagnosis and Treatment of Cancers

RNA and RNA Modification in the Pathogenesis, Diagnosis and Treatment of Cancers PDF Author: Dong-Hua Yang
Publisher: Frontiers Media SA
ISBN: 283250695X
Category : Medical
Languages : en
Pages : 364

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Book Description