Ribonucleases, Part B: Artificial and Engineered Ribonucleases and Speicifc Applications PDF Download
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Author:
Publisher: Elsevier
ISBN: 0080522572
Category : Science
Languages : en
Pages : 555
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Book Description
This second volume on ribonucleases provides up-to-date, methods-related information on these enzymes. Of particular interest to researchers will be the discussion of artificial and engineered ribonucleases, as well as the application of ribonucleases in medicine and biotechnology.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Author:
Publisher: Elsevier
ISBN: 0080522572
Category : Science
Languages : en
Pages : 555
Get Book Here
Book Description
This second volume on ribonucleases provides up-to-date, methods-related information on these enzymes. Of particular interest to researchers will be the discussion of artificial and engineered ribonucleases, as well as the application of ribonucleases in medicine and biotechnology.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Author: Tadhg P. Begley
Publisher: Wiley-Blackwell
ISBN:
Category : Science
Languages : en
Pages : 836
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Book Description
The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.
Author:
Publisher: Elsevier
ISBN: 0080496911
Category : Science
Languages : en
Pages : 771
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Book Description
This first of two volumes provides up-to-date, methods-related information on ribonuclease functions, assays, and applications. Chapter topics include the identification of, characterization of, and assays for secreted ribonucleases; viral ribonucleases, artificial and engineered ribonucleases, and ribozymes.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Author: Pierre Rousselot-pailley
Publisher: World Scientific
ISBN: 9811261679
Category : Science
Languages : en
Pages : 520
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Book Description
Peptides and proteins are crucial biomolecules in life. The manifold functions they carry out range from molecular recognition and signaling to catalysis and immune response. However, the native systems are limited to a reduced toolbox of chemical functionalities as well as tridimensional structures. Widening these toolboxes could pave the way to engineer peptides and proteins with enhanced properties compared to their native counterparts and/or with structures and functions unprecedented in Nature. Advances in the chemical and biological synthesis of peptides and proteins, in computational tools, in molecular biology and in high-throughput screening methods are making this realm possible.This book aims to give an overview of the last developments in the field of peptide and protein engineering. It comprises a collection of chapters that span from the production of simple non-proteinogenic building blocks and peptidic scaffolds of different sizes and structures to more complex systems including peptide-based nanomaterials, enzymes and artificial metalloenzymes. Different strategies are described where chemical and biological tools have been developed and combined to attain the desired properties and sought functionalities.The diverse systems described in this book highlight the progress in this important field and represent the starting points for the development of functional biomolecules, biomaterials and hybrid systems capable of addressing key societal challenges of our times in relevant areas such health, environment and energy.
Author:
Publisher: Elsevier
ISBN: 008049675X
Category : Science
Languages : en
Pages : 579
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Book Description
RNA-Ligand Interactions, Part B focuses on molecular biology methods. Major topics covered include: solution probe methods, tethered-probe methodologies, in vitro affinity selection methodologies, genetic methodologies for detecting RNA-protein interactions, protein engineering methodologies useful for RNA-protein interaction studies, and cell biology methods.RNA-Ligand Interactions, Part A, its companion, VOLUME 317 focuses on structural biology methods.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Author: Ajith Abraham
Publisher: Academic Press
ISBN: 0323902782
Category : Medical
Languages : en
Pages : 434
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Book Description
Artificial Intelligence for Neurological Disorders provides a comprehensive resource of state-of-the-art approaches for AI, big data analytics and machine learning-based neurological research. The book discusses many machine learning techniques to detect neurological diseases at the cellular level, as well as other applications such as image segmentation, classification and image indexing, neural networks and image processing methods. Chapters include AI techniques for the early detection of neurological disease and deep learning applications using brain imaging methods like EEG, MEG, fMRI, fNIRS and PET for seizure prediction or neuromuscular rehabilitation. The goal of this book is to provide readers with broad coverage of these methods to encourage an even wider adoption of AI, Machine Learning and Big Data Analytics for problem-solving and stimulating neurological research and therapy advances. - Discusses various AI and ML methods to apply for neurological research - Explores Deep Learning techniques for brain MRI images - Covers AI techniques for the early detection of neurological diseases and seizure prediction - Examines cognitive therapies using AI and Deep Learning methods
Author: Marina A. Zenkova
Publisher: Springer Science & Business Media
ISBN: 9783540201120
Category : Medical
Languages : en
Pages : 330
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Book Description
The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the immediate and very important applications they can find in the emerging fields of biotechnology and pharmacology. There are essentially two classes of these agents - nucleases that occur naturally inside cells and synthetically produced artificial nucleases. The first class includes protein enzyme nucle ases and catalytic RNA structured ribozymes that perform cleavage of the phosphodiester bonds in nucleic acids according to a hydrolytic pathway in the course of different biochemical processes in the cell. A different pathway is used by some antibiotics which cleave DNA via redox-based mechanisms resulting in oxidative damage of nucleotide units and breakage of the DNA backbone. The above molecules are indispensable tools for manipulating nucleic acids and processing RNA; DNA-cleaving antibiotics and cytotoxic ribonucleases have demonstrated utility as chemotherapeutic agents. The second class, artificial nucleases, are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets of the most important characteristics that are essential for catalysis. A dif ferent approach, in vitro selection, was also used to create artificial RNA and DNA enzymes capable of cleaving RNA. Being less efficient and specific as compared to the natural enzymes, the primitive mimics are smaller and robust and can function in a broad range of conditions.
Author: U.S. Atomic Energy Commission. Division of Technical Information
Publisher:
ISBN:
Category : Nuclear Energy
Languages : en
Pages : 626
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Book Description
Author: Ramaswamy, Krishnaraj
Publisher: IGI Global
ISBN:
Category : Science
Languages : en
Pages : 654
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Book Description
Nanomaterials, due to their tiny size and exceptional characteristics, are leading the way in scientific innovation, marking the beginning of a new era of technological progress and offering solutions to critical challenges faced by humanity. From their origin and theoretical foundations to their combination and extensive practical uses, the exploration of nanomaterials encompasses a wide range of knowledge and profound understanding, providing valuable perspectives on their revolutionary influence on different sectors of the economy. Nanomaterials possess distinctive characteristics, including enhanced strength, chemical reactivity, and electrical conductivity, distinguishing them from their larger counterparts. These characteristics stimulate innovative uses and improve current technologies, making them crucial in advancing engineering, medicine, energy solutions, and environmental sustainability. Exploring Nanomaterial Synthesis, Characterization, and Applications focuses on the interdisciplinary aspects of nanomaterials research and highlights their contributions to the advancement of medical science. This book offers a comprehensive overview of the present state of nanomaterial science and provide a glimpse into its promising future. Covering topics such as biosensing, energy storage, and pharmaceutical technology, this book is an excellent resource for academicians, researchers, graduate and postgraduate students, industry professionals, engineers, product developers, medical practitioners, policymakers, and more.
Author: U.S. Atomic Energy Commission
Publisher:
ISBN:
Category : Nuclear energy
Languages : en
Pages : 134
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Book Description
