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Author: Jay Schulkin
Publisher: Cambridge University Press
ISBN: 9780521811415
Category : Medical
Languages : en
Pages : 388
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Book Description
The concept of homeostasis, the maintenance of the internal physiological environment of an organism within tolerable limits, is well established in medicine and physiology. In contrast, allostasis is a relatively new idea of 'viability through change'. With allostatic regulation by cephalic involvement, the body adapts to potentially diverse and dangerous situations through the activation of neural, hormonal, or immunological mechanisms. Allostasis explains how regulatory events maintain organismic viability, or not, in diverse contexts with varying set points of bodily needs and competing motivations. This 2005 book introduces the concept of allostasis and sets it alongside traditional views of homeostasis. It addresses basic regulatory systems and examines the behavior of bodily regulation under duress. The basic concepts of physiological homeostasis are integrated with disorders like depression, stress, anxiety and addiction. It will therefore appeal to graduate students, medical students and researchers working in physiology, epidemiology, endocrinology, neuroendocrinology, neuroscience, and psychology.
Author: Jay Schulkin
Publisher: Cambridge University Press
ISBN: 9780521811415
Category : Medical
Languages : en
Pages : 388
Get Book Here
Book Description
The concept of homeostasis, the maintenance of the internal physiological environment of an organism within tolerable limits, is well established in medicine and physiology. In contrast, allostasis is a relatively new idea of 'viability through change'. With allostatic regulation by cephalic involvement, the body adapts to potentially diverse and dangerous situations through the activation of neural, hormonal, or immunological mechanisms. Allostasis explains how regulatory events maintain organismic viability, or not, in diverse contexts with varying set points of bodily needs and competing motivations. This 2005 book introduces the concept of allostasis and sets it alongside traditional views of homeostasis. It addresses basic regulatory systems and examines the behavior of bodily regulation under duress. The basic concepts of physiological homeostasis are integrated with disorders like depression, stress, anxiety and addiction. It will therefore appeal to graduate students, medical students and researchers working in physiology, epidemiology, endocrinology, neuroendocrinology, neuroscience, and psychology.
Author: Stephen C. Stearns
Publisher: Oxford University Press
ISBN: 0192871994
Category : Science
Languages : en
Pages : 510
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Book Description
Evolutionary thinking provides insights into many different areas in the research and practice of medicine and public health. It takes specialties such as medical microbiology, epidemiology, oncology, gynecology, and psychiatry that had become increasingly siloed and places them in a larger framework. This foundational structure enables students to view medical knowledge as an integrated whole, underpinned by general principles rather than a loose collection of disparate facts. The discipline of evolutionary medicine continues to advance rapidly as new results come in showing where the insights pay off and where they do not. Its conceptual foundations have also been strengthened in papers not yet reflected in the textbooks, so a new edition is therefore timely. At the same time, the teaching of evolutionary medicine has also been steadily gaining momentum both in courses that prepare undergraduates for medical school in North America and in other contexts worldwide. Evolutionary Medicine is intended for undergraduate students preparing for careers in medicine and public health, students in schools of medicine and public health, and medical professionals curious about the insights that evolutionary thinking can bring to their field. It will also be relevant to students and researchers in the fields of evolutionary biology, anthropology, developmental biology, and genetics. It highlights the most important insights in a relatively brief and compelling book that does not attempt encyclopedic coverage of a rapidly changing field.
Author:
Publisher: Academic Press
ISBN: 0080923232
Category : Science
Languages : en
Pages : 2275
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Book Description
Fish form an extremely diverse group of vertebrates. At a conservative estimate at least 40% of the world's vertebrates are fish. On the one hand they are united by their adaptations to an aquatic environment and on the other they show a variety of adaptations to differing environmental conditions - often to extremes of temperature, salinity, oxygen level and water chemistry. They exhibit an array of behavioural and reproductive systems. Interesting in their own right, this suite of adaptive physiologies provides many model systems for both comparative vertebrate and human physiologists. This four volume encyclopedia covers the diversity of fish physiology in over 300 articles and provides entry level information for students and summary overviews for researchers alike. Broadly organised into four themes, articles cover Functional, Thematic, and Phylogenetic Physiology, and Fish Genomics. Functional articles address the traditional aspects of fish physiology that are common to all areas of vertebrate physiology including: Reproduction, Respiration, Neural (Sensory, Central, Effector), Endocrinology, Renal, Cardiovascular, Acid-base Balance, Osmoregulation, Ionoregulation, Digestion, Metabolism, Locomotion, and so on. Thematic Physiology articles are carefully selected and fewer in number. They provide a level of integration that goes beyond the coverage in the Functional Physiology topics and include discussions of Toxicology, Air-breathing, Migrations, Temperature, Endothermy, etc. Phylogenetic Physiology articles bring together information that bridges the physiology of certain groupings of fishes where the knowledge base has a sufficient depth and breadth and include articles on Ancient Fishes, Tunas, Sharks, etc. Genomics articles describe the underlying genetic component of fish physiology and high light their suitability and use as model organisms for the study of disease, stress and physiological adaptations and reactions to external conditions. Winner of a 2011 PROSE Award Honorable Mention for Multivolume Science Reference from the Association of American Publishers The definitive encyclopedia for the field of fish physiology Three volumes which comprehensively cover the entire field in over 300 entries written by experts Detailed coverage of basic functional physiology of fishes, physiological themes in fish biology and comparative physiology amongst taxonomic Groups Describes the genomic bases of fish physiology and biology and the use of fish as model organisms in human physiological research Includes a glossary of terms
Author: Jay Schulkin
Publisher: MIT Press
ISBN: 9780262194808
Category : Medical
Languages : en
Pages : 332
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Book Description
An overview of allostasis, the process by which the body maintains overall viability under normal and adverse conditions.
Author: Nicholas Mrosovsky
Publisher: New York : Oxford University Press
ISBN:
Category : Literary Criticism
Languages : en
Pages : 200
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Book Description
This work offers a comprehensive re-examination and elaboration of homeostasis, a guiding principle in physiology that has received surprisingly little critical evaluation. Among the key topics addressed are questions concerning the competing demands of different regulatory systems within the body and the problem of maintaining equilibrium in such circumstances. The author makes the important point that the body does not always seek constancy of its internal environment, nor does it always react in ways that prevent change. On the contrary, sometimes physiological mechanisms actively promote change. These changes in regulated levels--termed "rheostasis"--are seen as having an adaptive value beyond a simple failure of homeostasis. This book compares and categorizes examples of rheostasis for a variety of physiological variables, and presents what is known about conflicts between different regulatory systems and their role in promoting the occurrence of rheostasis. Among other topics covered are weight loss during hibernation, calcium storage and reproduction, fever, and rates of fat deposition in adults. The work of an outstanding scholar, this integrative study represents a refreshing and essential new approach to one of the basic concepts in physiological science.
Author: Lynn B. Martin
Publisher: John Wiley & Sons
ISBN: 1118398785
Category : Science
Languages : en
Pages : 371
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Book Description
Integrative Organismal Biology synthesizes current understandings of the causes and consequences of individual variation at the physiological, behavioral and organismal levels. Emphasizing key topics such as phenotypic plasticity and flexibility, and summarizing emerging areas such as ecological immunology, oxidative stress biology and others, Integrative Organismal Biology pulls together information from diverse disciplines to provide a synthetic view of the role of the individual in evolution. Beginning with the role of the individual in evolutionary and ecological processes, the book covers theory and mechanism from both classic and modern perspectives. Chapters explore concepts such as phenotypic plasticity, genetic and epigenetic variation, physiological and phenotypic variation, homeostasis, and gene and physiological regulatory networks. A concluding section interweaves these concepts through a series of case studies of life processes such as aging, reproduction, and immune defense. Written and edited by leaders in the field, Integrative Organismal Biology will be an important advanced textbook for students and researchers across a variety of subdisciplines of integrative biology.
Author: Urs Albrecht
Publisher: Springer Science & Business Media
ISBN: 1441912622
Category : Science
Languages : en
Pages : 306
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Book Description
With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.
Author: Boon Lay Ong
Publisher: Routledge
ISBN: 1136309225
Category : Architecture
Languages : en
Pages : 223
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Book Description
Beyond Environmental Comfort highlights some of the key ideas that form the foundation of the field of environmental comfort and, at the same time, gives voice to some of the concerns and considerations on the limitations of the field as it stands today. Bringing together a range of foremost thinkers in their respective fields - Michel Cabanac, Derek Clements-Croome, Nick Baker, Harold Marshall, Juhani Pallasmaa, Dean Hawkes, and Constance Classen - this book argues for a deeper appreciation of how environmental comfort may be understood in terms of our relationship with the environment rather than as independent qualities. For the first time these diverse views are brought together by Editor Boon Lay Ong to present insights into a world beyond what is normally covered in academic research. In the process, an attempt is made to define the field for the future. This book shows that it is by understanding just how environmental design needs to go beyond mere comfort and deal with well-being that we can meaningfully design our future.
Author: Derek M Jones
Publisher: Routledge
ISBN: 1317196023
Category : Philosophy
Languages : en
Pages : 181
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Book Description
Philosophers have traditionally assumed that the difference between active and passive movement could be explained by the presence or absence of an intention in the mind of the agent. This assumption has led to the neglect of many interesting active behaviors that do not depend on intentions, including the "mindless" actions of humans and the activities of non-human animals. In this book Jones offers a broad account of agency that unifies these cases. The book addresses a range of questions, including: When are movements properly attributed to whole agents, rather than to their parts? What does it mean for an agent to guide its action? What distinguishes agents from other complex systems? What is the relationship between action and adaptive behavior? And why might the study of living systems be the key to understanding agency? This book makes an important contribution to current philosophical debate on the nature and origins of agency. It defines action as a uniquely biological process and recasts human intentional action as a specialized case of a broader and more common phenomenon than has been previously assumed. Uniting findings from philosophy, cognitive science, psychology, biology, computer science, complexity theory and ethology, this book will be of interest to students and scholars working in these areas.
Author: Larry R. Squire
Publisher: Academic Press
ISBN: 0080963935
Category : Medical
Languages : en
Pages : 12505
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Book Description
The Encyclopedia of the Neuroscience explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. Each article is written by an expert in that specific domain and peer reviewed by the advisory board before acceptance into the encyclopedia. Each article contains a glossary, introduction, a reference section, and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields.
