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Author: Jacopo P. Mortola
Publisher: JHU Press
ISBN: 0801873665
Category : Science
Languages : en
Pages : 363
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Book Description
Respiratory Physiology of Newborn Mammals: A Comparative Perspective emphasizes common trends among mammalian species in an effort to extract general rules about both the structure and the mechanisms of neonatal respiration. Jacopo P. Mortola outlines the key aspects of developmental respiratory physiology in the perinatal period. Based on what is learned from interspecies comparisons, Mortola addresses the question of how pulmonary ventilation fulfills the metabolic requirements of the newborn infant. Exceptions to the rules illuminate adaptations to particular tasks or conditions. Each chapter concludes with interspecies comparisons and clinical implications for the medically or zoologically oriented reader. The combination of developmental and comparative perspectives offers an original contribution to the field of developmental physiology. The book is divided into five chapters: "Gestation and Birth," Metabolic and Ventilatory Requirements," "Mechanical Behavior of the Respiratory Pump," "Reflex Control of the Breathing Pattern," and "Changes in Temperature and Respiratory Gases." It will be of value to researchers, clinicians, and students interested in developmental physiology, comparative biology, and zoology, as well as neonatalogists and pediatric pulmonologists who are interested in alternative perspectives on current clinical practice.
Author: Jacopo P. Mortola
Publisher: JHU Press
ISBN: 0801873665
Category : Science
Languages : en
Pages : 363
Get Book Here
Book Description
Respiratory Physiology of Newborn Mammals: A Comparative Perspective emphasizes common trends among mammalian species in an effort to extract general rules about both the structure and the mechanisms of neonatal respiration. Jacopo P. Mortola outlines the key aspects of developmental respiratory physiology in the perinatal period. Based on what is learned from interspecies comparisons, Mortola addresses the question of how pulmonary ventilation fulfills the metabolic requirements of the newborn infant. Exceptions to the rules illuminate adaptations to particular tasks or conditions. Each chapter concludes with interspecies comparisons and clinical implications for the medically or zoologically oriented reader. The combination of developmental and comparative perspectives offers an original contribution to the field of developmental physiology. The book is divided into five chapters: "Gestation and Birth," Metabolic and Ventilatory Requirements," "Mechanical Behavior of the Respiratory Pump," "Reflex Control of the Breathing Pattern," and "Changes in Temperature and Respiratory Gases." It will be of value to researchers, clinicians, and students interested in developmental physiology, comparative biology, and zoology, as well as neonatalogists and pediatric pulmonologists who are interested in alternative perspectives on current clinical practice.
Author: Alan H. Jobe
Publisher: Cambridge University Press
ISBN: 1316665178
Category : Medical
Languages : en
Pages :
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Book Description
Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development and is designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book covers genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going in order to improve outcomes for patients with common and rare lung diseases.
Author: Shyamala Dakshinamurti
Publisher: CRC Press
ISBN: 1000442322
Category : Medical
Languages : en
Pages : 268
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Book Description
We have all been hypoxic. Fetal tolerance for intrauterine hypoxia arises from evolutionarily conserved physiological mechanisms, the antecedents of which can be learned from diving mammals or species at high altitudes. Understanding fetal hypoxia leads to understanding the huge physiological shifts of neonatal transition and the dangers of perinatal hypoxia. This comprehensive volume of topical review articles by expert authors addresses the origins of hypoxia tolerance, the impact of oxygen on circulatory transition at birth, and the biochemistry of hypoxia in the pulmonary circuit, as well as the classification, diagnosis, and clinical management of hypoxic respiratory failure and persistent pulmonary hypertension in the term neonate. The goal of Hypoxic Respiratory Failure in the Newborn is to connect our understanding of hypoxia from animals in extreme environments, with how the human fetus handles its hypoxic environment; and why the human newborn suddenly cannot. The book will educate health care professionals on how to care for newborns with hypoxic respiratory failure, including the use of up-to-date diagnostic tools and therapies. It also highlights areas of controversy and ongoing research in hypoxic respiratory failure and pulmonary hypertension of the newborn, including challenging case studies. Key Features Explores evolutionary context and comparative physiology of hypoxia tolerance in the fetus and neonate, from basic research to clinical scenarios Provides guidance to trainees, physicians, and allied health professionals engaged in NICU care; pediatricians, cardiologists, pulmonologists, anesthesiologists, neonatologists, and physiologists to effectively manage infants in hypoxic respiratory failure Includes case scenarios emphasizing current diagnostic and therapeutic controversies and algorithmic approaches to decipher difficult clinical cases
Author: Roger S. Seymour
Publisher: Springer Science & Business Media
ISBN: 9400965362
Category : Science
Languages : en
Pages : 439
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Book Description
The papers in this volume were presented at an international symposium, held in South Australia on September 8-10, 1983. The purpose of the meeting was to present the comparative physiology of gas exchange, water balance and energet ics of developing vertebrate embryos. contributions were invited from leading research workers in an attempt to represent the forefront of investigation of all vertebrate classes and to promote a broadly comparative approach to the study of embryonic physiology. These proceedings therefore reflect the current level of research activity focus ing on each group of vertebrates. While considerable expansion and specializa tion has occurred in the area of avian embryos over the last decade, work on reptilian embryos is less developed and that on fish and amphibians is still in its infancy. Although a great deal is known about respiration and metabolism in embryos of placental mammals, the physiology associated with the curious mode of development of monotreme and marsupial embryos has not been examined until recently. In this symposium. the well-studied vertebrate classes are repre sented primarily by specific research papers that document original work. These are balanced by more extensive reviews of the lesser known classes.
Author: Roger W. Byard
Publisher:
ISBN: 9781925261677
Category : Medical
Languages : en
Pages : 844
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Book Description
This volume covers aspects of sudden infant and early childhood death, ranging from issues with parental grief, to the most recent theories of brainstem neurotransmitters. It also deals with the changes that have occurred over time with the definitions of SIDS (sudden infant death syndrome), SUDI (sudden unexpected death in infancy) and SUDIC (sudden unexpected death in childhood). The text will be indispensable for SIDS researchers, SIDS organisations, paediatric pathologists, forensic pathologists, paediatricians and families, in addition to residents in training programs that involve paediatrics. It will also be of use to other physicians, lawyers and law enforcement officials who deal with these cases, and should be a useful addition to all medical examiner/forensic, paediatric and pathology departments, hospital and university libraries on a global scale. Given the marked changes that have occurred in the epidemiology and understanding of SIDS and sudden death in the very young over the past decade, a text such as this is very timely and is also urgently needed.
Author: National Research Council
Publisher: National Academies Press
ISBN: 030916785X
Category : Science
Languages : en
Pages : 223
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Book Description
Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
Author: Peter C. Rimensberger
Publisher: Springer
ISBN: 3642012191
Category : Medical
Languages : en
Pages : 1584
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Book Description
Written by outstanding authorities from all over the world, this comprehensive new textbook on pediatric and neonatal ventilation puts the focus on the effective delivery of respiratory support to children, infants and newborns. In the early chapters, developmental issues concerning the respiratory system are considered, physiological and mechanical principles are introduced and airway management and conventional and alternative ventilation techniques are discussed. Thereafter, the rational use of mechanical ventilation in various pediatric and neonatal pathologies is explained, with the emphasis on a practical step-by-step approach. Respiratory monitoring and safety issues in ventilated patients are considered in detail, and many other topics of interest to the bedside clinician are covered, including the ethics of withdrawal of respiratory support and educational issues. Throughout, the text is complemented by numerous illustrations and key information is clearly summarized in tables and lists.
Author: C. Hugh Tyndale-Biscoe
Publisher: Cambridge University Press
ISBN: 9780521337922
Category : Nature
Languages : en
Pages : 496
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Book Description
The results of this compilation of new research on the reproductive physiology of marsupials reveal much about their patterns of reproduction and evolution in comparison to monotremes and eutherians.
Author: Claude Gaultier
Publisher: Springer
ISBN: 1461475376
Category : Medical
Languages : en
Pages : 464
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Book Description
Knowledge about the mechanisms of lung development has been growing rapidly, especially with regard to cellular and molecular aspects of growth and differentiation. This authoritative international volume reviews key aspects of lung development in health and disease by providing a comprehensive review of the complex series of cellular and molecular interactions required for lung development. It covers such topics as pulmonary hypoplasia, effects of malnutrition, and pulmaonary angiogenesis. An indispensable reference for all those involved in studying or treating lung disease in neonates and children, the book offers a unique view of the development of this essential organ.
Author: A. V. S. de Reuck
Publisher: John Wiley & Sons
ISBN: 0470717025
Category : Science
Languages : en
Pages : 466
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Book Description
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
