Research of Pathogenesis and Novel Therapeutics in Arthritis

Research of Pathogenesis and Novel Therapeutics in Arthritis PDF Author: Chih-Hsin Tang
Publisher: MDPI
ISBN: 3038970654
Category : Medical
Languages : en
Pages : 366

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Book Description
Arthritis has a high prevalence globally and includes over 100 different types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. The exact etiology of arthritis remains unclear and no cure exists. Anti-inflammatory drugs are commonly used in the treatment of arthritis but are associated with significant side effects. Novel modes of therapy and additional prognostic biomarkers are urgently needed for arthritis patients. This book summarizes and discusses the global picture of the current understanding of arthritis.

Research of Pathogenesis and Novel Therapeutics in Arthritis

Research of Pathogenesis and Novel Therapeutics in Arthritis PDF Author: Chih-Hsin Tang
Publisher: MDPI
ISBN: 3038970654
Category : Medical
Languages : en
Pages : 366

Get Book Here

Book Description
Arthritis has a high prevalence globally and includes over 100 different types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. The exact etiology of arthritis remains unclear and no cure exists. Anti-inflammatory drugs are commonly used in the treatment of arthritis but are associated with significant side effects. Novel modes of therapy and additional prognostic biomarkers are urgently needed for arthritis patients. This book summarizes and discusses the global picture of the current understanding of arthritis.

Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0

Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0 PDF Author: Chih-Hsin Tang
Publisher:
ISBN: 9783036575933
Category :
Languages : en
Pages : 0

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Book Description
Arthritis has a high prevalence globally and includes over 100 types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. All types of arthritis share common features of the disease, including monocyte infiltration, inflammation, synovial swelling, pannus formation, stiffness in the joints, and articular cartilage destruction. The exact etiology of arthritis remains unclear, and no cure exists as of yet. Anti-inflammatory drugs (NSAIDs and corticosteroids) are commonly used in the treatment of arthritis. However, these drugs are associated with significant side effects, such as gastric bleeding and an increased risk of heart attack and other cardiovascular problems. It is therefore crucial that we continue to research the pathogenesis of arthritis and seek to discover novel modes of therapy. This reprint summarizes the themes of the 29 articles published in our Special Issue “Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0”. This reprint details important novel research discoveries that contribute to our current understanding of arthritis.

Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0

Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0 PDF Author: Hih-Hsin Tang
Publisher: Mdpi AG
ISBN: 9783036575926
Category :
Languages : en
Pages : 0

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Book Description
Arthritis has a high prevalence globally and includes over 100 types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. All types of arthritis share common features of the disease, including monocyte infiltration, inflammation, synovial swelling, pannus formation, stiffness in the joints, and articular cartilage destruction. The exact etiology of arthritis remains unclear, and no cure exists as of yet. Anti-inflammatory drugs (NSAIDs and corticosteroids) are commonly used in the treatment of arthritis. However, these drugs are associated with significant side effects, such as gastric bleeding and an increased risk of heart attack and other cardiovascular problems. It is therefore crucial that we continue to research the pathogenesis of arthritis and seek to discover novel modes of therapy. This book summarizes the themes of the 29 articles published in our Special Issue "Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0". This book details important novel research discoveries that contribute to our current understanding of arthritis.

T Cells in Arthritis

T Cells in Arthritis PDF Author: P. Miossec
Publisher: Springer Science & Business Media
ISBN: 9783764358532
Category : Medical
Languages : en
Pages : 256

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Book Description
Rheumatoid arthritis (RA) is the most common and most severe form of inflammatory arthritis. The pathogenesis of RA has been the subject of intense research for several decades. The prevailing hypotheses have changed over the years, and have attempted to incorporate the most recent data. Although T cells represent an important component of the cells which infiltrate the joint synovium, their contribution at a late stage of the disease remains a matter of debate. The goal of this book is to outline the major arguments and data suggesting that T cells may, or may not, be central players in the pathogenesis of chronic RA. While each of the editors and authors has his/her own bias (as will be clear by reading the respective chapters), our hope is that the readers will enjoy a complete and balanced view of the critical questions and experiments. This is not just an intellectual exercise since the direction of future therapeutic interventions depends heavily on how one interprets the pathogenesis of RA and the contribution of T cells.

Research of Pathogenesis and Novel Therapeutics in Arthritis

Research of Pathogenesis and Novel Therapeutics in Arthritis PDF Author: Chih-Hsin Tang
Publisher:
ISBN: 9783038970668
Category : Medicine (General)
Languages : en
Pages : 366

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Book Description
Arthritis has a high prevalence globally and includes over 100 different types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. The exact etiology of arthritis remains unclear and no cure exists. Anti-inflammatory drugs are commonly used in the treatment of arthritis but are associated with significant side effects. Novel modes of therapy and additional prognostic biomarkers are urgently needed for arthritis patients. This book summarizes and discusses the global picture of the current understanding of arthritis.

Mayo Clinic Internal Medicine Board Review Questions and Answers

Mayo Clinic Internal Medicine Board Review Questions and Answers PDF Author: Robert D. Ficalora
Publisher: Oxford University Press, USA
ISBN: 0199985871
Category : Medical
Languages : en
Pages : 164

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Book Description
Companion volume to: Mayo Clinic internal medicine board review. 10th ed. c2013.

Research of Pathogenesis and Novel Therapeutics in Arthritis 3.0

Research of Pathogenesis and Novel Therapeutics in Arthritis 3.0 PDF Author: Chih-Hsin Tang
Publisher:
ISBN: 9783036580852
Category : Arthritis
Languages : en
Pages : 0

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Book Description
Arthritis has a high prevalence globally and includes over 100 types; the most common types are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. All types of arthritis share common features, including monocyte infiltration, inflammation, synovial swelling, pannus formation, stiffness in the joints, and articular cartilage destruction. The exact etiology of arthritis remains unclear, and no cure exists as of yet. Anti-inflammatory drugs (NSAIDs and corticosteroids) are commonly used for the treatment of arthritis. However, these drugs are associated with significant side effects, such as gastric bleeding and an increased risk of a heart attack and other cardiovascular problems. Therefore, it is crucial that we continue to research the pathogenesis of arthritis and novel modes of therapy. This reprint summarizes and discusses the themes of 19 articles published in our Special Issue "Research of Pathogenesis and Novel Therapeutics in Arthritis 3.0". The reprint details important novel research discoveries that contribute to our current understanding of arthritis.

Periprosthetic Joint Infection: Practical Management Guide

Periprosthetic Joint Infection: Practical Management Guide PDF Author: Parvizi Javad
Publisher: JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.
ISBN: 9350908255
Category : Medical
Languages : en
Pages : 432

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Book Description
This book Periprosthetic Joint Infection is a portable guide to the practical management of surgical site infections following orthopedic procedures. It designed to help answer clinician's questions regarding the prevention and treatment of periprosthetic infections. It organized for rapid review, featuring evidence reviews, pitfalls, Rothman Institute Current Practices and Controversies. The guide is being included in the course materials for the 29th Annual Current Concepts in Joint Replacement® (CCJR) meeting thanks to a generous educational grant from 3M Health Care.

The Resolution of Inflammation

The Resolution of Inflammation PDF Author: Adriano Rossi
Publisher: Springer Science & Business Media
ISBN: 376437506X
Category : Medical
Languages : en
Pages : 246

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Book Description
This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.

The Cytokine Network

The Cytokine Network PDF Author: Frances R. Balkwill
Publisher: Frontiers in Molecular Biology
ISBN: 9780199637027
Category : Cytokines
Languages : en
Pages : 222

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Book Description
Cytokines are soluble mediators of intercellular communication. They contribute to a chemical signalling language that regulates development, tissue repair, haemopoiesis, inflammation and the immune response. Potent cytokine polypepides have pleiotropic activities and functional redundancy.They act in a complex network where one cytokine can influence the production of, and response to, many other cytokines. In the past five years, this bewildering array of more than 100 effector molecules and associated cell surface receptors has been simplified by study of cytokine and cytokinereceptor structure; elucidation of convergent intracellular signalling pathways; and molecular genetics, and targeted gene disruption to 'knock-out' production of individual cytokines in mice. It is also now clear that the pathophysiology of infectious, autoimmune and malignant disease can bepartially explained by the induction of cytokines and the subsequent cellular response. Viral homologues exist for many cytokines and receptors and genetic variations in cytokine production may influence response to pathogenic stimuli. Cytokine and cytokine antagonists have shown therapeuticpotential in a number of chronic and acute diseases. The Cytokine Network: Frontiers in Molecular Biology is not a survey of individual cytokines, but guides the reader through the latest research on the cytokine network as a whole covering genomics, signalling pathways, control of the immuneresponse, and therapeutics.