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Author: Jill Williamson
Publisher: Zonderkidz
ISBN: 0310727596
Category : Juvenile Fiction
Languages : en
Pages : 370
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Book Description
A girl discovers her geneticist father is covering up multiple secrets—all of which are named Jason. Jason 3:3—known as Martyr—always believed his life had purpose. As one of the hundreds of clones living in a closed-off underground facility beneath an Alaskan farm, he has been told his genetics hold the key to saving humanity from an airborne pandemic aboveground, and his purpose will be filled on his upcoming eighteenth birthday. The problem is no such pandemic exists. Unaware of the truth, Martyr wishes for one glimpse of the sky before his expiration date arrives. His escape leads him to the home of one of the scientists, and to Abby Goyer. As she helps Martyr, she can’t help but notice his uncanny resemblance to the high school quarterback. Abby soon uncovers the dark truth behind Jason Farms and her dad’s work, and decides to show Martyr his true value and worth. As Martyr learns the truth behind his existence, he must decide if his God-given purpose is connected to the farm, or if it rests in a life with Abby.
Author: Jill Williamson
Publisher: Zonderkidz
ISBN: 0310727596
Category : Juvenile Fiction
Languages : en
Pages : 370
Get Book Here
Book Description
A girl discovers her geneticist father is covering up multiple secrets—all of which are named Jason. Jason 3:3—known as Martyr—always believed his life had purpose. As one of the hundreds of clones living in a closed-off underground facility beneath an Alaskan farm, he has been told his genetics hold the key to saving humanity from an airborne pandemic aboveground, and his purpose will be filled on his upcoming eighteenth birthday. The problem is no such pandemic exists. Unaware of the truth, Martyr wishes for one glimpse of the sky before his expiration date arrives. His escape leads him to the home of one of the scientists, and to Abby Goyer. As she helps Martyr, she can’t help but notice his uncanny resemblance to the high school quarterback. Abby soon uncovers the dark truth behind Jason Farms and her dad’s work, and decides to show Martyr his true value and worth. As Martyr learns the truth behind his existence, he must decide if his God-given purpose is connected to the farm, or if it rests in a life with Abby.
Author: Bernadette Charron-Bost
Publisher: Springer Science & Business Media
ISBN: 3642112935
Category : Computers
Languages : en
Pages : 298
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Book Description
Consistency models for replicated data /Alan D. Fekete and Krithi Ramamritham --Replication techniques for availability /Robbert van Renesse and Rachid Guerraoui --Modular approach to replication for availability /Fernando Pedone and André Schiper --Stumbling over consensus research: misunderstandings and issues /Marcos K. Aguilera --Replicating for performance: case studies /Maarten van Steen and Guillaume Pierre --A history of the virtual synchrony replication model /Ken Birman --From viewstamped replication to byzantine fault tolerance /Barbara Liskov --Implementing trustworthy services using replicated state machines /Fred B. Schneider and Lidong Zhou --State machine replication with Byzantine faults /Christian Cachin --Selected results from the latest decade of quorum systems research /Michael G. Merideth and Michael K. Reiter --From object replication to database replication /Fernando Pedone and André Schiper --Database replication: a tutorial /Dettina Kemme, Ricardo Jiménez-Peris, Marta Patiño-Martínez, and Gustavo Alonso --Practical database replication /Alfrânio Correia Jr. ... [et al.].
Author: Lynne Suzanne Cox
Publisher: Royal Society of Chemistry
ISBN: 0854041648
Category : Science
Languages : en
Pages : 467
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Book Description
Written by leading experts, this learned but accessible book highlights the latest work on eukaryotic DNA replication.
Author: Proceedings of the National Academy of Sciences
Publisher: National Academies Press
ISBN: 030907424X
Category : Science
Languages : en
Pages : 303
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Book Description
There has been a sea change in how we view genetic recombination. When germ cells are produced in higher organisms, genetic recombination assures the proper segregation of like chromosomes. In the course of that process, called meiosis, recombination not only assures segregation of one chromosome of each type to progeny germ cells, but also further shuffles the genetic deck, contributing to the unique inheritance of individuals. In a nutshell, that is the classical view of recombination. We have also known for many years that in bacteria recombination plays a role in horizontal gene transfer and in replication itself, the latter by establishing some of the replication forks that are the structural scaffolds for copying DNA. In recent years, however, we have become increasingly aware that replication, which normally starts without any help from recombination, is a vulnerable process that frequently leads to broken DNA. The enzymes of recombination play a vital role in the repair of those breaks. The recombination enzymes can function via several different pathways that mediate the repair of breaks, as well as restoration of replication forks that are stalled by other kinds of damage to DNA. Thus, to the classical view of recombination as an engine of inheritance we must add the view of recombination as a vital housekeeping function that repairs breaks suffered in the course of replication. We have also known for many years that genomic instability--including mutations, chromosomal rearrangements, and aneuploidy--is a hallmark of cancer cells. Although genomic instability has many contributing causes, including faulty replication, there are many indications that recombination, faulty or not, contributes to genome instability and cancer as well. The (Nas colloquium) Links Between Recombination and Replication: Vital Roles of Recombination was convened to broaden awareness of this evolving area of research. Papers generated by this colloquium are published here. To encourage the desired interactions of specialists, we invited some contributions that deal only with recombination or replication in addition to contributions on the central thesis of functional links between recombination and replication. To aid the nonspecialist and specialist alike, we open the set of papers with a historical overview by Michael Cox and we close the set with a commentary on the meeting and the field by Andrei Kuzminov.
Author: Herve Seligmann
Publisher: BoD – Books on Demand
ISBN: 9533075937
Category : Medical
Languages : en
Pages : 712
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Book Description
The study of DNA advanced human knowledge in a way comparable to the major theories in physics, surpassed only by discoveries such as fire or the number zero. However, it also created conceptual shortcuts, beliefs and misunderstandings that obscure the natural phenomena, hindering its better understanding. The deep conviction that no human knowledge is perfect, but only perfectible, should function as a fair safeguard against scientific dogmatism and enable open discussion. With this aim, this book will offer to its readers 30 chapters on current trends in the field of DNA replication. As several contributions in this book show, the study of DNA will continue for a while to be a leading front of scientific activities.
Author: Samantha Fowler
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 1409
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Book Description
Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.
Author: Melvin L. DePamphilis
Publisher: CSHL Press
ISBN: 0879697660
Category : Medical
Languages : en
Pages : 814
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Book Description
At least 5 trillion cell divisions are required for a fertilized egg to develop into an adult human, resulting in the production of more than 20 trillion meters of DNA! And yet, with only two exceptions, the genome is replicated once and only once each time a cell divides. How is this feat accomplished? What happens when errors occur? This book addresses these questions by presenting a thorough analysis of the molecular events that govern DNA replication in eukaryotic cells. The association between genome replication and cell proliferation, disease pathogenesis, and the development of targeted therapeutics is also addressed. At least 160 proteins are involved in replicating the human genome, and at least 40 diseases are caused by aberrant DNA replication, 35 by mutations in genes required for DNA replication or repair, 7 by mutations generated during mitochondrial DNA replication, and more than 40 by DNA viruses. Consequently, a growing number of therapeutic drugs are targeted to DNA replication proteins. This authoritative volume provides a rich source of information for researchers, physicians, and teachers, and will stimulate thinking about the relevance of DNA replication to human disease.
Author: Arthur Kornberg
Publisher: University Science Books
ISBN: 9781891389443
Category : Science
Languages : en
Pages : 964
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Book Description
DNA Replication, second edition, a classic of modernscience, is now back in print in a paperback edition. Kornberg and Baker'sinsightful coverage of DNA replication and related cellular processes have madethis the standard reference in the field.
Author: Bettina Kemme
Publisher: Morgan & Claypool Publishers
ISBN: 1608453812
Category : Computers
Languages : en
Pages : 154
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Book Description
Database replication is widely used for fault-tolerance, scalability and performance. The failure of one database replica does not stop the system from working as available replicas can take over the tasks of the failed replica. Scalability can be achieved by distributing the load across all replicas, and adding new replicas should the load increase. Finally, database replication can provide fast local access, even if clients are geographically distributed clients, if data copies are located close to clients. Despite its advantages, replication is not a straightforward technique to apply, and there are many hurdles to overcome. At the forefront is replica control: assuring that data copies remain consistent when updates occur. There exist many alternatives in regard to where updates can occur and when changes are propagated to data copies, how changes are applied, where the replication tool is located, etc. A particular challenge is to combine replica control with transaction management as it requires several operations to be treated as a single logical unit, and it provides atomicity, consistency, isolation and durability across the replicated system. The book provides a categorization of replica control mechanisms, presents several replica and concurrency control mechanisms in detail, and discusses many of the issues that arise when such solutions need to be implemented within or on top of relational database systems. Table of Contents: Overview / 1-Copy-Equivalence and Consistency / Basic Protocols / Replication Architecture / The Scalability of Replication / Eager Replication and 1-Copy-Serializability / 1-Copy-Snapshot Isolation / Lazy Replication / Self-Configuration and Elasticity / Other Aspects of Replication
Author: John Garmany
Publisher: Rampant TechPress
ISBN: 9780972751339
Category : Computers
Languages : en
Pages : 244
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Book Description
With the advent of inexpensive and fast worldwide connectivity, many Oracle professionals recognize the benefits of distributing Oracle data; however, Oracle multi-master replication is extremely complex and time-consuming to implement. This book addresses the complexity of Oracle replication by providing working code examples and illustrations of working systems. Demonstrated is every aspect of Oracle snapshot replication, including syntax for refresh intervals, managing snapshot logs, monitoring oracle replication, and refresh timings. Also detailed are techniques for implementing conflict resolution in multi-master replication.
