Regulation of Uncoupling Protein Gene Expression by Endurance Exercise in Human Skeletal Muscle PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Regulation of Uncoupling Protein Gene Expression by Endurance Exercise in Human Skeletal Muscle PDF full book. Access full book title Regulation of Uncoupling Protein Gene Expression by Endurance Exercise in Human Skeletal Muscle by Robert C. Noland. Download full books in PDF and EPUB format.
Author: Robert C. Noland
Publisher:
ISBN:
Category : Cycling
Languages : en
Pages : 254
Get Book Here
Book Description
Author: Robert C. Noland
Publisher:
ISBN:
Category : Cycling
Languages : en
Pages : 254
Get Book Here
Book Description
Author: Neil Spurway
Publisher: Elsevier Health Sciences
ISBN: 0443100772
Category : Medical
Languages : en
Pages : 285
Get Book Here
Book Description
This title is directed primarily towards health care professionals outside of the United States. It starts with the origin of life and ends with the mechanisms that make muscles adapt to different forms of training. In between, it considers how evidence has been obtained about the extent of genetic influence on human capacities, how muscles and their fibres are studied for general properties and individual differences, and how molecular biological techniques have been combined with physiological ones to produce the new discipline of molecular exercise physiology. This is the first book on such topics written specifically for modules in exercise and sport science at final year Hons BSc and taught MSc levels.
Author: Dean J. Calsbeek
Publisher:
ISBN:
Category : Muscle proteins
Languages : en
Pages : 142
Get Book Here
Book Description
Author:
Publisher:
ISBN: 9789178314812
Category :
Languages : en
Pages :
Get Book Here
Book Description
Author: Yorgos N. Kraniou
Publisher:
ISBN:
Category : Carbohydrates
Languages : en
Pages : 170
Get Book Here
Book Description
Twenty two, young, healthy individuals participated in three studies aiming to assess the effect of various types of physical activity - acute exercise of moderate intensity and duration, varying intensity, short-term training - on skeletal muscle GLUT-4 gene and protein expression as well as on a range of genes encoding the proteins involved in carbohydrate metabolism in skeletal muscle.
Author: Brian Carson
Publisher:
ISBN:
Category :
Languages : en
Pages : 175
Get Book Here
Book Description
Author: Robert J. Shute
Publisher:
ISBN: 9781321693461
Category : Adaptation (Physiology)
Languages : en
Pages : 110
Get Book Here
Book Description
Endurance exercise in the cold when coupled with recovery in the cold has been shown to effect the expression of select genes to a greater extent than room temperature exercise and recovery. However, it is not known whether endurance exercise in the cold without recovery in the cold elicits this same gene response. Purpose: To determine mitochondrial related gene expression response to exercise in a cold compared to room temperature environment. Methods: Recreationally trained males (N = 9, age: 25 ± 4 y, height: 179 ± 5 cm, weight: 76.2 ± 8.0 kg, %BF: 13.4 ± 3.3%, VO2peak: 4.39 ± 0.82 L/min) each completed two trials consisting of cycling in a cold (C) or room temperature (RT) environment (7.2 ± 0.2 and 20.1 ± 0.2 °C, respectively) for one hour at 60% of the workload associated with VO2peak followed by 3 hours of room temperature recovery. Muscle biopsies were taken from the vastus lateralis pre-exercise and three hours post-exercise for gene expression analysis. Heart rate (HR) and expired gases were also measured throughout the trials. Results: Exercise V02 was lower in C than N (2.68 ± 0.8, 2.81 ± 5.2 L/min, respectively, p = 0.017). HR was similar during exercise and recovery between C and N. Environmental temperatures (p = 0.238) and V02 (p = 0.924) were not different during recovery. PGC-1&agr; and VEGF increased with exercise (p = 0.001, p = 0.001, respectively) but were not different between trials (p = 0.134 and p = 0.975, respectively). ERR&agr; was lower three hours after exercise in C compared to N (p = 0.033). There was a trend toward MEF2A and NRF-2 being lower in C than N (p = 0.086, p = 0.055) but no effect of exercise (p = 0.786, p = 0.256). NRF-1 and TFAM did not change with exercise (p = 0.281, p = 0.117, respectively) or differ between trials (p = 0.981, p = 0.854, respectively). Conclusion: These results indicate that when exercise is performed in a cold environment, select mRNA associated with mitochondrial biogenesis are altered in a manner that would appear to inhibit mitochondrial biogenesis.
Author: Manfred Lamprecht
Publisher: CRC Press
ISBN: 1466567570
Category : Medical
Languages : en
Pages : 304
Get Book Here
Book Description
The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Author: Roberto Scatena
Publisher: Springer Science & Business Media
ISBN: 9400728689
Category : Medical
Languages : en
Pages : 459
Get Book Here
Book Description
Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly related to redox control of gene expression and so on. This functional and structural complexity may undergo important derangements so to justify the definition of ‘mitochondrial medicine’, which should include all the clinical consequences of congenital or acquired mitochondrial dysfunctions. There are actually a growing number of studies which assign a significant pathogenic role to damaged mitochondria in different diseases: ischemia/reperfusion injury, neurodegenerative diseases, cancer with its dramatic sequelae (i.e, metastasis), metabolic syndrome, hyperlipidemias, just to mention a few of the most important pathologies. In this context, a further aspect that should not be disregarded is the interaction of pharmacological agents with mitochondria, not only in regard of the toxicological aspects but, above all, of the potential therapeutic applications. In fact, it is interesting to note that, while the properties of different so-called “mitoxicants” are well-known, the subtle linkages between drugs and mitochondria is still in need of a real pharmacological and therapeutic control at the clinical level. This lack of consideration can often lead to an underestimation of unwanted toxic effects but also of desirable therapeutic activities. A reevaluation of the potential clinical role of mitochondria could give a new light on some yet obscure aspects of human pathophysiology.
Author: Shlomo Melmed
Publisher: Elsevier Health Sciences
ISBN: 1437736009
Category : Medical
Languages : en
Pages : 1920
Get Book Here
Book Description
The latest edition of Williams Textbook of Endocrinology edited by Drs. Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, and Henry M. Kronenberg, helps you diagnose and treat your patients effectively with up-to-the minute, practical know-how on all endocrine system disorders. Comprehensive yet accessible, this extensively revised 12th Edition updates you on diabetes, metabolic syndrome, obesity, thyroid disease, testicular disorders, and much more so you can provide your patients with the most successful treatments. Find scientific insight and clinical data interwoven in every chapter, reflecting advances in both areas of this constantly changing discipline, and presented in a truly accessible format. You’ll also access valuable contributions from a dynamic list of expert authors and nearly 2.000 full-color images to help you with every diagnosis. This title has everything you need to manage any and all the clinical endocrinopathies you may encounter. Rely on the one reference that integrates rapidly evolving basic and clinical science in a cohesive, user-friendly format, definitively addresses every topic in the field, and has remained a standard for more than half a century. Update your know-how and skills to diagnose and treat your patients most effectively with exhaustively revised content on diabetes, metabolic disease, thyroid cancer, fertility problems, testicular problems, weight issues, and much more. Apply reliable guidance on endocrine conditions of growing interest like hypothyroidism and testicular disorders, with dedicated new chapters that expound on the latest research findings. Overcome any clinical challenge with comprehensive and easy-to-use coverage of everything from hormone activity, diagnostic techniques, imaging modalities, and molecular genetics, to total care of the patient. Apply the latest practices with guidance from expert authors who contribute fresh perspectives on every topic.
