Regulation of Chemokine- Receptor Interactions and Functions

Regulation of Chemokine- Receptor Interactions and Functions PDF Author: Martin J. Stone
Publisher: MDPI
ISBN: 3038427284
Category : Medical
Languages : en
Pages : 229

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Book Description
This book is a printed edition of the Special Issue "Regulation of Chemokine-Receptor Interactions and Functions" that was published in IJMS

Regulation of Chemokine- Receptor Interactions and Functions

Regulation of Chemokine- Receptor Interactions and Functions PDF Author: Martin J. Stone
Publisher: MDPI
ISBN: 3038427284
Category : Medical
Languages : en
Pages : 229

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Book Description
This book is a printed edition of the Special Issue "Regulation of Chemokine-Receptor Interactions and Functions" that was published in IJMS

The Chemokine Receptors

The Chemokine Receptors PDF Author: Jeffrey K. Harrison
Publisher: Springer Science & Business Media
ISBN: 1597450200
Category : Medical
Languages : en
Pages : 412

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Book Description
This volume, new to The Receptors series, focuses on several areas, including the birth, maturation, and structure of Chemokines; Neutrophil, Dendritic, and Lymphocyte trafficking; and Chemokine Receptors in diseases such as AIDs and lung cancer. In particular the book contains cutting-edge information ranging from basic molecular and cellular mechanisms to physiological and pathological roles of chemokines.

Interleukin-8 (NAP-1) and Related Chemotactic Cytokines

Interleukin-8 (NAP-1) and Related Chemotactic Cytokines PDF Author: Marco Baggiolini
Publisher: Karger Medical and Scientific Publishers
ISBN: 9783805554268
Category : Medical
Languages : en
Pages : 172

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Book Description


Sensory Nerves

Sensory Nerves PDF Author: Brendan J. Canning
Publisher: Springer Science & Business Media
ISBN: 354079090X
Category : Medical
Languages : en
Pages : 623

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Book Description
The intention of this book is to provide a comprehensive and contemporary review of the biology of sensory nerves. The book is unique, as it comprehensively covers the role of sensory nerves across many therapeutic areas.

Chemokines and Skin

Chemokines and Skin PDF Author: Eckhard Kownatzki
Publisher: Nelson Thornes
ISBN: 9783764358181
Category : Medical
Languages : en
Pages : 160

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Book Description
Chemokines: Attraction of dendritic cells and role in tumor immunobiology.- Chemokine receptors.- Regulation of gene expression of chemokines and their receptors.- Chemokines and T lymphocytes.- Chemokines and mast cells.- Chemokines and eosinophils.- CXC-chemokines - autocrine growth factors for melanoma and epidermoid carcinoma cells.- Expression of chemokines in dermatoses.

The Cytokines of the Immune System

The Cytokines of the Immune System PDF Author: Zlatko Dembic
Publisher: Academic Press
ISBN: 0124200109
Category : Medical
Languages : en
Pages : 323

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Book Description
The Cytokines of the Immune System catalogs cytokines and links them to physiology and pathology, providing a welcome and hugely timely tool for scientists in all related fields. In cataloguing cytokines, it lists their potential for therapeutic use, links them to disease treatments needing further research and development, and shows their utility for learning about the immune system. This book offers a new approach in the study of cytokines by combining detailed guidebook-style cytokine description, disease linking, and presentation of immunologic roles. - Supplies new ideas for basic and clinical research - Provides cytokine descriptions in a guidebook-style, cataloging the origins, structures, functions, receptors, disease-linkage, and therapeutic potentials - Offers a textbook-style view on the immune system with the immunologic role of each cytokine

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades PDF Author: Wolfgang B. Liedtke, MD, PH.D.
Publisher: CRC Press
ISBN: 1420005847
Category : Medical
Languages : en
Pages : 502

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Book Description
Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

Encyclopedia of Signaling Molecules

Encyclopedia of Signaling Molecules PDF Author: Sangdun Choi
Publisher: Springer
ISBN: 9781441904607
Category : Medical
Languages : en
Pages : 0

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Book Description
Biological processes are driven by complex systems of functionally interacting signaling molecules. Thus, understanding signaling molecules is essential to explain normal or pathological biological phenomena. A large body of clinical and experimental data has been accumulated over these years, albeit in fragmented state. Hence, systems biological approaches concomitant with the understanding of each molecule are ideal to delineate signaling networks/pathways involved in the biologically important processes. The control of these signaling pathways will enrich our healthier life. Currently, there are more than 30,000 genes in human genome. However, not all the proteins encoded by these genes work equally in order to maintain homeostasis. Understanding the important signaling molecules as completely as possible will significantly improve our research-based teaching and scientific capabilities. This encyclopedia presents 350 biologically important signaling molecules and the content is built on the core concepts of their functions along with early findings written by some of the world’s foremost experts. The molecules are described by recognized leaders in each molecule. The interactions of these single molecules in signal transduction networks will also be explored. This encyclopedia marks a new era in overview of current cellular signaling molecules for the specialist and the interested non-specialist alike During past years, there were multiple databases to gather this information briefly and very partially. Amidst the excitement of these findings, one of the great scientific tasks of the coming century is to bring all the useful information into a place. Such an approach is arduous but at the end will infuse the lacunas and considerably be a streamline in the understanding of vibrant signaling networks. Based on this easy-approach, we can build up more complicated biological systems.

Glucocorticoid Signaling

Glucocorticoid Signaling PDF Author: Jen-Chywan Wang
Publisher: Springer
ISBN: 1493928953
Category : Science
Languages : en
Pages : 387

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Book Description
This timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the third section will cover the effects of glucocorticoids on key tissues. The final section will discuss general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume will be of interest to both researchers and clinicians.

GPCR Signaling in Cancer

GPCR Signaling in Cancer PDF Author:
Publisher: Academic Press
ISBN: 0128202300
Category : Science
Languages : en
Pages : 164

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Book Description
GPCR Signaling in Cancer, Volume 145, the latest release in the Advances in Cancer Research series, highlights recent developments in the area of GPCRs and cancer biology. Chapters included in this volume cover several GPCRs and their downstream effectors as case examples to highlight their fundamental understanding and therapeutic potential. Specific chapters address the Role of GRKs and beta-arrestins in cancer, Atypical GPCRs in cancer, the Role of a chemokine receptor (CCR) 5 in cancer, Targeting G protein-coupled receptors for therapeutics in cancer, Emerging GPCR signaling pathways in cancer, and more. G protein-coupled receptors (GPCRs) constitute a large family of cell surface receptors which are involved in nearly every cellular and physiological event. These receptors can recognize a broad array of ligands and they are targeted by nearly one third of the currently prescribed drugs including anti-cancer therapeutics.