Author: Constantinos K. Zacharis
Publisher: MDPI
ISBN: 3036507981
Category : Science
Languages : en
Pages : 166
Book Description
This book covers the most recent research trends and applications of Pharmaceutical Analytical Chemistry. The included topics range from the adulteration of dietary supplements, to the determination of drugs in biological samples with the aim to investigate their pharmacokinetic properties.
Recent Trends in Pharmaceutical Analytical Chemistry
Author: Constantinos K. Zacharis
Publisher: MDPI
ISBN: 3036507981
Category : Science
Languages : en
Pages : 166
Book Description
This book covers the most recent research trends and applications of Pharmaceutical Analytical Chemistry. The included topics range from the adulteration of dietary supplements, to the determination of drugs in biological samples with the aim to investigate their pharmacokinetic properties.
Publisher: MDPI
ISBN: 3036507981
Category : Science
Languages : en
Pages : 166
Book Description
This book covers the most recent research trends and applications of Pharmaceutical Analytical Chemistry. The included topics range from the adulteration of dietary supplements, to the determination of drugs in biological samples with the aim to investigate their pharmacokinetic properties.
Analytical Method Development and Validation
Author: Michael E. Swartz
Publisher: CRC Press
ISBN: 1482229773
Category : Science
Languages : en
Pages : 95
Book Description
Describes analytical methods development, optimization and validation, and provides examples of successful methods development and validation in high-performance liquid chromatography (HPLC) areas. The text presents an overview of Food and Drug Administration (FDA)/International Conference on Harmonization (ICH) regulatory guidelines, compliance with validation requirements for regulatory agencies, and methods validation criteria stipulated by the US Pharmacopia, FDA and ICH.
Publisher: CRC Press
ISBN: 1482229773
Category : Science
Languages : en
Pages : 95
Book Description
Describes analytical methods development, optimization and validation, and provides examples of successful methods development and validation in high-performance liquid chromatography (HPLC) areas. The text presents an overview of Food and Drug Administration (FDA)/International Conference on Harmonization (ICH) regulatory guidelines, compliance with validation requirements for regulatory agencies, and methods validation criteria stipulated by the US Pharmacopia, FDA and ICH.
Introduction to Pharmaceutical Analytical Chemistry
Author: Stig Pedersen-Bjergaard
Publisher: John Wiley & Sons
ISBN: 111936275X
Category : Science
Languages : en
Pages : 752
Book Description
The definitive textbook on the chemical analysis of pharmaceutical drugs – fully revised and updated Introduction to Pharmaceutical Analytical Chemistry enables students to gain fundamental knowledge of the vital concepts, techniques and applications of the chemical analysis of pharmaceutical ingredients, final pharmaceutical products and drug substances in biological fluids. A unique emphasis on pharmaceutical laboratory practices, such as sample preparation and separation techniques, provides an efficient and practical educational framework for undergraduate studies in areas such as pharmaceutical sciences, analytical chemistry and forensic analysis. Suitable for foundational courses, this essential undergraduate text introduces the common analytical methods used in quantitative and qualitative chemical analysis of pharmaceuticals. This extensively revised second edition includes a new chapter on chemical analysis of biopharmaceuticals, which includes discussions on identification, purity testing and assay of peptide and protein-based formulations. Also new to this edition are improved colour illustrations and tables, a streamlined chapter structure and text revised for increased clarity and comprehension. Introduces the fundamental concepts of pharmaceutical analytical chemistry and statistics Presents a systematic investigation of pharmaceutical applications absent from other textbooks on the subject Examines various analytical techniques commonly used in pharmaceutical laboratories Provides practice problems, up-to-date practical examples and detailed illustrations Includes updated content aligned with the current European and United States Pharmacopeia regulations and guidelines Covering the analytical techniques and concepts necessary for pharmaceutical analytical chemistry, Introduction to Pharmaceutical Analytical Chemistry is ideally suited for students of chemical and pharmaceutical sciences as well as analytical chemists transitioning into the field of pharmaceutical analytical chemistry.
Publisher: John Wiley & Sons
ISBN: 111936275X
Category : Science
Languages : en
Pages : 752
Book Description
The definitive textbook on the chemical analysis of pharmaceutical drugs – fully revised and updated Introduction to Pharmaceutical Analytical Chemistry enables students to gain fundamental knowledge of the vital concepts, techniques and applications of the chemical analysis of pharmaceutical ingredients, final pharmaceutical products and drug substances in biological fluids. A unique emphasis on pharmaceutical laboratory practices, such as sample preparation and separation techniques, provides an efficient and practical educational framework for undergraduate studies in areas such as pharmaceutical sciences, analytical chemistry and forensic analysis. Suitable for foundational courses, this essential undergraduate text introduces the common analytical methods used in quantitative and qualitative chemical analysis of pharmaceuticals. This extensively revised second edition includes a new chapter on chemical analysis of biopharmaceuticals, which includes discussions on identification, purity testing and assay of peptide and protein-based formulations. Also new to this edition are improved colour illustrations and tables, a streamlined chapter structure and text revised for increased clarity and comprehension. Introduces the fundamental concepts of pharmaceutical analytical chemistry and statistics Presents a systematic investigation of pharmaceutical applications absent from other textbooks on the subject Examines various analytical techniques commonly used in pharmaceutical laboratories Provides practice problems, up-to-date practical examples and detailed illustrations Includes updated content aligned with the current European and United States Pharmacopeia regulations and guidelines Covering the analytical techniques and concepts necessary for pharmaceutical analytical chemistry, Introduction to Pharmaceutical Analytical Chemistry is ideally suited for students of chemical and pharmaceutical sciences as well as analytical chemists transitioning into the field of pharmaceutical analytical chemistry.
Recent Advances in Analytical Techniques
Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 1681085720
Category : Science
Languages : en
Pages : 313
Book Description
Recent Advances in Analytical Techniques is a series of updates in techniques used in chemical analysis. Each volume presents a selection of chapters that explain different analytical techniques and their use in applied research. Readers will find updated information about developments in analytical methods such as chromatography, electrochemistry, optical sensor arrays for pharmaceutical and biomedical analysis. The third volume of the series features seven reviews on a variety of techniques: · Chiral Analysis of Methamphetamine and Related Controlled Substances in Forensic Science · Low-cost feedstocks for biofuels and high value added products production: Using multi-parameter flow cytometry as a tool to enhance the process efficiency · Recent Trends in the Application of Ionic Liquids for Micro Extraction Techniques · Electrospun Nanofibers: Functional and Attractive Materials for the Sensing and Separation Approaches in Analytical Chemistry · Neutron Activation Analysis: An Overview · Non-commercial Polysaccharides-based Chiral Selectors in Enantioselective Chromatography · Ru(II)-polypyridyl Complexes as Potential Sensing Agents for Cations and Anions.
Publisher: Bentham Science Publishers
ISBN: 1681085720
Category : Science
Languages : en
Pages : 313
Book Description
Recent Advances in Analytical Techniques is a series of updates in techniques used in chemical analysis. Each volume presents a selection of chapters that explain different analytical techniques and their use in applied research. Readers will find updated information about developments in analytical methods such as chromatography, electrochemistry, optical sensor arrays for pharmaceutical and biomedical analysis. The third volume of the series features seven reviews on a variety of techniques: · Chiral Analysis of Methamphetamine and Related Controlled Substances in Forensic Science · Low-cost feedstocks for biofuels and high value added products production: Using multi-parameter flow cytometry as a tool to enhance the process efficiency · Recent Trends in the Application of Ionic Liquids for Micro Extraction Techniques · Electrospun Nanofibers: Functional and Attractive Materials for the Sensing and Separation Approaches in Analytical Chemistry · Neutron Activation Analysis: An Overview · Non-commercial Polysaccharides-based Chiral Selectors in Enantioselective Chromatography · Ru(II)-polypyridyl Complexes as Potential Sensing Agents for Cations and Anions.
Ionic Liquids in Analytical Chemistry
Author: Samuel Carda-Broch
Publisher: Elsevier
ISBN: 0128233354
Category : Science
Languages : en
Pages : 428
Book Description
Ionic liquids in Analytical Chemistry: New Insights and Recent Developments focuses on the use of these materials in the field of chemical analysis, paying attention to different areas such as sample preparation, separation techniques, spectroscopy and electrochemical methods. Chapters describe the structure and properties of new ionic liquids and eutectic solvents that are widely used in analytical chemistry, review ionic liquids in sample preparation, liquid, micellar liquid and gas chromatography, and capillary electrophoresis. Final chapters are devoted to spectroscopic and electrochemical techniques. The whole volume provides a broad overview of recent applications of ionic liquids. The book will serve as a valuable resource to researchers and laboratory technicians working in the field, as well as instructors and students of analytical chemistry. Gathers the contributions of leading authorities on the use of ionic liquids in analytical science Describes the structure and properties of the newer ionic liquids used in chemical analysis Examines the new performance of ionic liquids in analytical chemistry applications
Publisher: Elsevier
ISBN: 0128233354
Category : Science
Languages : en
Pages : 428
Book Description
Ionic liquids in Analytical Chemistry: New Insights and Recent Developments focuses on the use of these materials in the field of chemical analysis, paying attention to different areas such as sample preparation, separation techniques, spectroscopy and electrochemical methods. Chapters describe the structure and properties of new ionic liquids and eutectic solvents that are widely used in analytical chemistry, review ionic liquids in sample preparation, liquid, micellar liquid and gas chromatography, and capillary electrophoresis. Final chapters are devoted to spectroscopic and electrochemical techniques. The whole volume provides a broad overview of recent applications of ionic liquids. The book will serve as a valuable resource to researchers and laboratory technicians working in the field, as well as instructors and students of analytical chemistry. Gathers the contributions of leading authorities on the use of ionic liquids in analytical science Describes the structure and properties of the newer ionic liquids used in chemical analysis Examines the new performance of ionic liquids in analytical chemistry applications
Novel Developments in Pharmaceutical and Biomedical Analysis
Author: Atta-ur- Rahman
Publisher: Bentham Science Publishers
ISBN: 1681085747
Category : Science
Languages : en
Pages : 466
Book Description
Recent Advances in Analytical Techniques is a series of updates in techniques used in chemical analysis. Each volume presents information about a selection of analytical techniques. Readers will find information about developments in analytical methods such as chromatography, electrochemistry, optical sensor arrays for pharmaceutical and biomedical analysis. Novel Developments in Pharmaceutical and Biomedical Analysis is the second volume of the series and covers the following topics: o Chromatographic assays of solid dosage forms and their drug dissolution studies o UHPLC method for the estimation of bioactive compounds o HILIC based LC/MS for metabolite analysis o In vitro methods for the evaluation of oxidative stress o Application of vibrational spectroscopy in studies of structural polymorphism of drugs o Electrochemical sensors based on conductive polymers and carbon nanotubes o Optical sensor arrays for pharmaceutical and biomedical analyses o Chemical applications of ionic liquids o New trends in enantioanalysis of pharmaceutical compounds
Publisher: Bentham Science Publishers
ISBN: 1681085747
Category : Science
Languages : en
Pages : 466
Book Description
Recent Advances in Analytical Techniques is a series of updates in techniques used in chemical analysis. Each volume presents information about a selection of analytical techniques. Readers will find information about developments in analytical methods such as chromatography, electrochemistry, optical sensor arrays for pharmaceutical and biomedical analysis. Novel Developments in Pharmaceutical and Biomedical Analysis is the second volume of the series and covers the following topics: o Chromatographic assays of solid dosage forms and their drug dissolution studies o UHPLC method for the estimation of bioactive compounds o HILIC based LC/MS for metabolite analysis o In vitro methods for the evaluation of oxidative stress o Application of vibrational spectroscopy in studies of structural polymorphism of drugs o Electrochemical sensors based on conductive polymers and carbon nanotubes o Optical sensor arrays for pharmaceutical and biomedical analyses o Chemical applications of ionic liquids o New trends in enantioanalysis of pharmaceutical compounds
MODERN PHARMACEUTICAL ANALYTICAL TECHNIQUES
Author: Mrs. Mitali Yogesh Patil
Publisher: JEC PUBLICATION
ISBN: 9358504951
Category : Medical
Languages : en
Pages : 229
Book Description
In the dynamic realm of pharmaceutical sciences, this project explores "Modern Pharmaceutical Analytical Techniques," delving into cutting-edge methodologies crucial for ensuring the quality and efficacy of drugs. From spectroscopy to advanced technologies like metabolomics, each chapter demystifies the application and significance of these techniques. Bridging academia and industry, this work aims to be a practical guide, underlining the realworld implications of these tools. Gratitude is extended to mentors, colleagues, and institutions, as this concise exploration seeks to serve students, researchers, and professionals navigating the ever-evolving landscape of pharmaceutical analysis.
Publisher: JEC PUBLICATION
ISBN: 9358504951
Category : Medical
Languages : en
Pages : 229
Book Description
In the dynamic realm of pharmaceutical sciences, this project explores "Modern Pharmaceutical Analytical Techniques," delving into cutting-edge methodologies crucial for ensuring the quality and efficacy of drugs. From spectroscopy to advanced technologies like metabolomics, each chapter demystifies the application and significance of these techniques. Bridging academia and industry, this work aims to be a practical guide, underlining the realworld implications of these tools. Gratitude is extended to mentors, colleagues, and institutions, as this concise exploration seeks to serve students, researchers, and professionals navigating the ever-evolving landscape of pharmaceutical analysis.
HPLC for Pharmaceutical Scientists
Author: Yuri V. Kazakevich
Publisher: John Wiley & Sons
ISBN: 0470087943
Category : Science
Languages : en
Pages : 1136
Book Description
HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.
Publisher: John Wiley & Sons
ISBN: 0470087943
Category : Science
Languages : en
Pages : 1136
Book Description
HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.
Pharmaceutical Process Development
Author: John Blacker
Publisher: Royal Society of Chemistry
ISBN: 1849733074
Category : Science
Languages : en
Pages : 375
Book Description
Pharmaceutical process research and development is an exacting, multidisciplinary effort but a somewhat neglected discipline in the chemical curriculum. This book presents an overview of the many facets of process development and how recent advances in synthetic organic chemistry, process technology and chemical engineering have impacted on the manufacture of pharmaceuticals. In 15 concise chapters the book covers such diverse subjects as route selection and economics, the interface with medicinal chemistry, the impact of green chemistry, safety, the crucial role of physical organic measurements in gaining a deeper understanding of chemical behaviour, the role of the analyst, new tools and innovations in reactor design, purification and separation, solid state chemistry and its role in formulation. The book ends with an assessment of future trends and challenges. The book provides a valuable overview of: both early and late stage chemical development, how safe and scaleable synthetic routes are designed, selected and developed, the importance of the chemical engineering, analytical and manufacturing interfaces, the key enabling technologies, including catalysis and biocatalysis, the importance of the green chemical perspective and solid form issues. The book, written and edited by experts in the field, is a contemporary, holistic treatise, with a logical sequence for process development and mini-case histories within the chapters to bring alive different aspects of the process. It is completely pharmaceutical themed, encompassing all essential aspects, from route and reagent selection to manufacture of the active compound. The book is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry. It informs them about the breadth of the work carried out in chemical research and development departments, and gives them a feel for the challenges involved in the job. The book is also of value to academics who often understand the drug discovery arena, but have far less appreciation of the drug development area, and are thus unable to advise their students about the relative merits of careers in chemical development versus discovery.
Publisher: Royal Society of Chemistry
ISBN: 1849733074
Category : Science
Languages : en
Pages : 375
Book Description
Pharmaceutical process research and development is an exacting, multidisciplinary effort but a somewhat neglected discipline in the chemical curriculum. This book presents an overview of the many facets of process development and how recent advances in synthetic organic chemistry, process technology and chemical engineering have impacted on the manufacture of pharmaceuticals. In 15 concise chapters the book covers such diverse subjects as route selection and economics, the interface with medicinal chemistry, the impact of green chemistry, safety, the crucial role of physical organic measurements in gaining a deeper understanding of chemical behaviour, the role of the analyst, new tools and innovations in reactor design, purification and separation, solid state chemistry and its role in formulation. The book ends with an assessment of future trends and challenges. The book provides a valuable overview of: both early and late stage chemical development, how safe and scaleable synthetic routes are designed, selected and developed, the importance of the chemical engineering, analytical and manufacturing interfaces, the key enabling technologies, including catalysis and biocatalysis, the importance of the green chemical perspective and solid form issues. The book, written and edited by experts in the field, is a contemporary, holistic treatise, with a logical sequence for process development and mini-case histories within the chapters to bring alive different aspects of the process. It is completely pharmaceutical themed, encompassing all essential aspects, from route and reagent selection to manufacture of the active compound. The book is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry. It informs them about the breadth of the work carried out in chemical research and development departments, and gives them a feel for the challenges involved in the job. The book is also of value to academics who often understand the drug discovery arena, but have far less appreciation of the drug development area, and are thus unable to advise their students about the relative merits of careers in chemical development versus discovery.
Solid-Phase Extraction
Author: Colin F. Poole
Publisher: Elsevier
ISBN: 0128169079
Category : Science
Languages : en
Pages : 742
Book Description
Solid Phase Extraction thoroughly presents both new and historic techniques for dealing with solid phase extraction. It provides all information laboratory scientists need for choosing and utilizing suitable sample preparation procedures for any kind of sample. In addition, the book showcases the contemporary uses of sample preparation techniques in the most important industrial and academic project environments, including solid-phase Microextraction, molecularly imprinted polymers, magnetic nanoparticles, and more. Written by recognized experts in their respective fields, this one-stop reference is ideal for those who need to know which technique to choose for solid phase extraction. Used in conjunction with a similar release, Liquid Phase Extraction, this book allows users to master this crucial aspect of sample preparation. - Defines the current state-of-the-art in extraction techniques and the methods and procedures for implementing them in laboratory practice - Includes extensive referencing that facilitates the identification of key information - Aimed at both entry-level scientists and those who want to explore new techniques and methods
Publisher: Elsevier
ISBN: 0128169079
Category : Science
Languages : en
Pages : 742
Book Description
Solid Phase Extraction thoroughly presents both new and historic techniques for dealing with solid phase extraction. It provides all information laboratory scientists need for choosing and utilizing suitable sample preparation procedures for any kind of sample. In addition, the book showcases the contemporary uses of sample preparation techniques in the most important industrial and academic project environments, including solid-phase Microextraction, molecularly imprinted polymers, magnetic nanoparticles, and more. Written by recognized experts in their respective fields, this one-stop reference is ideal for those who need to know which technique to choose for solid phase extraction. Used in conjunction with a similar release, Liquid Phase Extraction, this book allows users to master this crucial aspect of sample preparation. - Defines the current state-of-the-art in extraction techniques and the methods and procedures for implementing them in laboratory practice - Includes extensive referencing that facilitates the identification of key information - Aimed at both entry-level scientists and those who want to explore new techniques and methods