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Author: Jagdish N. Sharma
Publisher: Springer
ISBN: 3319066838
Category : Medical
Languages : en
Pages : 203
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Book Description
This volume presents key topics of current interest with regard to several pathophysiological conditions including (a) the basic and clinical aspects of bradykinin receptor antagonists, (b) the kallikrein-kinin pathways in hypertension and diabetes, (c) tissue kallikrein-kinin therapy for hypertension and organ damage, (d) the renal (tissue) kallikrein-kinin system in the kidney and novel potential drugs for salt-sensitive hypertension, (e) the kallikrein-kinin system in diabetes retinopathy, and (f) genetic manipulation and genetic variation of the kallikrein-kinin system and their impacts on cardiovascular and renal disease. Written by internationally reputed scientists, the book provides an essential overview of the latest developments in the field of kinin research, making it a valuable asset for endocrinologists, nephrologists, cardiologists, pharmacologists, physiologists, ophthalmologists and rheumatologists. Furthermore, it is also intended for postgraduate students in the fields of medicine, pharmacy, physiology and pharmacology, and those working at research organizations.
Author: Jagdish N. Sharma
Publisher: Springer
ISBN: 3319066838
Category : Medical
Languages : en
Pages : 203
Get Book Here
Book Description
This volume presents key topics of current interest with regard to several pathophysiological conditions including (a) the basic and clinical aspects of bradykinin receptor antagonists, (b) the kallikrein-kinin pathways in hypertension and diabetes, (c) tissue kallikrein-kinin therapy for hypertension and organ damage, (d) the renal (tissue) kallikrein-kinin system in the kidney and novel potential drugs for salt-sensitive hypertension, (e) the kallikrein-kinin system in diabetes retinopathy, and (f) genetic manipulation and genetic variation of the kallikrein-kinin system and their impacts on cardiovascular and renal disease. Written by internationally reputed scientists, the book provides an essential overview of the latest developments in the field of kinin research, making it a valuable asset for endocrinologists, nephrologists, cardiologists, pharmacologists, physiologists, ophthalmologists and rheumatologists. Furthermore, it is also intended for postgraduate students in the fields of medicine, pharmacy, physiology and pharmacology, and those working at research organizations.
Author: 国立国会図書館 (Japan)
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 672
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Book Description
Author:
Publisher: Birkhäuser
ISBN: 9783764385309
Category : Medical
Languages : en
Pages : 0
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Book Description
Inflammation has become one of the most exciting and rewarding areas of medical research. Recent years have seen a revolution in our understanding of how blood and tissue cells interact and of the intracellular mechanisms controlling their activation. This has revealed the underlying inflammatory pathology of many diseases and provided multiple new targets for anti-inflammatory and immunomodulatory therapy. The Encyclopedia of Inflammatory Diseases will cover the following areas: Inflammatory Processes and Cells Inflammatory Diseases Mediators of Inflammation Pharmacology of Inflammation Since inflammatory diseases and their therapy cover a broad range of scientific and medical fields, the encyclopedia will be co-edited by four international experts, a clinician and three researchers from the disciplines of immunology, biochemistry, and pharmacology, in this way providing students, basic and clinical scientists and practitioners in academia, hospitals and industry with valuable interlinked information. This living project will serve as a reliable and comprehensive data pool for everybody working in inflammation research. Owing to its dynamic nature, it will grow with time and future editions, becoming an indispensible source of information for academia, clinical practitioners and industry.
Author:
Publisher:
ISBN:
Category : Alcoholism
Languages : en
Pages : 496
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Book Description
Author: Marc Galanter
Publisher: Springer Science & Business Media
ISBN: 1489916954
Category : Medical
Languages : en
Pages : 461
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Book Description
From the President of the Research Society on Alcoholism In recent years the alcohol research field has matured and is attracting a substantial number of eager and technically sophisticated researchers. There is a feeling of excitement and premonitions of breakthroughs as more and more of alcohol's actions are being detailed. I, however, have at times been sobered by the perception that the lure of parsimonious explanations and the appeal of studying easily demonstrable effects obscure the critical issues re garding alcohol abuse and alcoholism. Central questions regarding (1) the reinforcing properties of ethanol and other factors responsible for inappro priate consumption of alcohol, (2) the heterogenous characteristics (both bi ologic and sociologic) of the alcoholic population, and (3) the differential predisposition of individuals to alcohol-induced medical problems needed to be vigorously pursued. Researchers who used animals as models for the human condition needed to become more intimately aware of the variety of factors that are of importance in the development of alcoholism in an indi vidual. On the other hand, researchers studying humans needed to attempt to more clearly define and categorize diagnostic criteria and characteristics of various alcoholic populations. Such categorization and continued character ization of alcoholism allows not only for a framework of concepts within which proper animal models for studies of biologic mechanisms can be de veloped but also allows for consideration of the most apt treatment approaches.
Author: M. Raabe
Publisher: Springer Science & Business Media
ISBN: 1461308054
Category : Science
Languages : en
Pages : 514
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Book Description
The most striking fact revealed by investigations of insect neurohormones is that insects are as well supplied with neurohormones as mammals, since neurohor mones regulate not only the functioning of the endocrine glands, prothoracic gland, and corpora allata, but also most physiological processes. Our knowledge of neurohormones developed originally from anat omocytological investigations and experimental studies. Today, accurate bio assays have been devised for studying both in vivo and in vitro physiological processes, and RIA determination has yielded knowledge of titer modifications of humoral factors. Much is also known about neurohormone purification, and several neurohormones have even been identified in different species. Immunocytochemistry has made it possible to demonstrate in their origin and release sites the presence of insect neurohormones whose structure has been elucidated. Moreover, the presence of vertebrate and invertebrate neuropeptides has been demonstrated in insects. As regards biogenic amines, methods of detection have been greatly refined and it is now possible to identify the cell bodies and axons of the main biogenic amines. Other new methods, such as cobalt chloride impregnation or Lucifer yellow staining, have revealed the axonal pathways and the location of particular neurons. The mechanisms of action of neurohormones have been investigated in several cases and the results of these investigations will be related in the chapters which follow.
Author: John Coltart
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 380
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Book Description
Author: Stephen G. Farmer
Publisher: Academic Press
ISBN: 0080542522
Category : Medical
Languages : en
Pages : 371
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Book Description
Bradykinin is a type of plasma hormone that causes blood vessels to dilate, resulting in a drop in blood pressure, the contraction of muscles in the lungs, intestines, and uterus, and pain. The Kinin System reviews the molecular biology of the kinins through their roles in a complex array of inflammatory conditions such as asthma, GI disease, cardiovascular complaints and examines the future therapeutic opportunities. From the prepublication reviews:"A delicious masterpiece."--Chef's DigestThe Kinin System is a comprehensive, timely book covering all aspects of the kinin system from its disocvery to the pathophysiology, pharmacology, and molecular biology of the mechanisms regulating kinin production to kinin receptors in health and disease. The authors take a refreshingly different view of the kinin system than previous books on the subject. Several chapters contain new information on the gene expression, regulation, and cell surface presentation of kininogens and kallikreins, as well as new data, some of it from human studies, on the role of kinins in pain angiogenesis, tissue repair, sepsis, arthritis, asthma, allergic rhinits, myocardial ischemia, and other diseases. * * Offers new information on kinin reception, regulation of gene expression of receptors, and kinin-generating proteins.* Provides a distinctly immunopharmacological approach to the kinin system.* Reviews of the role of kinins in disease and inlcudes data from human studies.* Includes information that is fully up-to-date and comprehensive.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1516
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Book Description
Author: 国立国会図書館 (Japan)
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 672
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Book Description
