The Quest for the Cure

The Quest for the Cure PDF Author: Brent R. Stockwell
Publisher: Columbia University Press
ISBN: 0231525524
Category : Medical
Languages : en
Pages : 289

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Book Description
After more than fifty years of blockbuster drug development, skeptics are beginning to fear we are reaching the end of drug discovery to combat major diseases. In this engaging book, Brent R. Stockwell, a leading researcher in the exciting new science of chemical biology, describes this dilemma and the powerful techniques that may bring drug research into the twenty-first century. Filled with absorbing stories of breakthroughs, this book begins with the scientific achievements of the twentieth century that led to today's drug innovations. We learn how the invention of mustard gas in World War I led to early anti-cancer agents and how the efforts to decode the human genome might lead to new approaches in drug design. Stockwell then turns to the seemingly incurable diseases we face today, such as Alzheimer's, many cancers, and others with no truly effective medicines, and details the cellular and molecular barriers thwarting scientists equipped with only the tools of traditional pharmaceutical research. Scientists such as Stockwell are now developing methods to combat these complexities technologies for constructing and testing millions of drug candidates, sophisticated computational modeling, and entirely new classes of drug molecules all with an eye toward solving the most profound mysteries of living systems and finding cures for intractable diseases. If successful, these methods will unlock a vast terrain of untapped drug targets that could lead to a bounty of breakthrough medicines. Offering a rare, behind-the-scenes look at this cutting-edge research, The Quest for the Cure tells a thrilling story of science, persistence, and the quest to develop a new generation of cures.

The Quest for the Cure

The Quest for the Cure PDF Author: Brent R. Stockwell
Publisher: Columbia University Press
ISBN: 0231525524
Category : Medical
Languages : en
Pages : 289

Get Book Here

Book Description
After more than fifty years of blockbuster drug development, skeptics are beginning to fear we are reaching the end of drug discovery to combat major diseases. In this engaging book, Brent R. Stockwell, a leading researcher in the exciting new science of chemical biology, describes this dilemma and the powerful techniques that may bring drug research into the twenty-first century. Filled with absorbing stories of breakthroughs, this book begins with the scientific achievements of the twentieth century that led to today's drug innovations. We learn how the invention of mustard gas in World War I led to early anti-cancer agents and how the efforts to decode the human genome might lead to new approaches in drug design. Stockwell then turns to the seemingly incurable diseases we face today, such as Alzheimer's, many cancers, and others with no truly effective medicines, and details the cellular and molecular barriers thwarting scientists equipped with only the tools of traditional pharmaceutical research. Scientists such as Stockwell are now developing methods to combat these complexities technologies for constructing and testing millions of drug candidates, sophisticated computational modeling, and entirely new classes of drug molecules all with an eye toward solving the most profound mysteries of living systems and finding cures for intractable diseases. If successful, these methods will unlock a vast terrain of untapped drug targets that could lead to a bounty of breakthrough medicines. Offering a rare, behind-the-scenes look at this cutting-edge research, The Quest for the Cure tells a thrilling story of science, persistence, and the quest to develop a new generation of cures.

Science and the Spiritual Quest

Science and the Spiritual Quest PDF Author: W. Mark Richardson
Publisher: Psychology Press
ISBN: 9780415257671
Category : Philosophy
Languages : en
Pages : 292

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Book Description
Addressing fundamental questions about life, this unique volume examines the way in which distinguished scientists of different faiths explore the connections between science, ethics, spirituality and the divine.

The Awakened Brain

The Awakened Brain PDF Author: Lisa Miller
Publisher: Random House
ISBN: 198485562X
Category : Psychology
Languages : en
Pages : 289

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Book Description
A groundbreaking exploration of the neuroscience of spirituality and a bold new paradigm for health, healing, and resilience—from a New York Times bestselling author and award-winning researcher “A new revolution of health and well-being and a testament to, and celebration of, the power within.”—Deepak Chopra, MD Whether it’s meditation or a walk in nature, reading a sacred text or saying a prayer, there are many ways to tap into a heightened awareness of the world around you and your place in it. In The Awakened Brain, psychologist Dr. Lisa Miller shows you how. Weaving her own deeply personal journey of awakening with her groundbreaking research, Dr. Miller’s book reveals that humans are universally equipped with a capacity for spirituality, and that our brains become more resilient and robust as a result of it. For leaders in business and government, truth-seekers, parents, healers, educators, and any person confronting life’s biggest questions, The Awakened Brain combines cutting-edge science (from MRI studies to genetic research, epidemiology, and more) with on-the-ground application for people of all ages and from all walks of life, illuminating the surprising science of spirituality and how to engage it in our lives: • The awakened decision is the better decision. With an awakened perception, we are more creative, collaborative, ethical, and innovative. • The awakened brain is the healthier brain. An engaged spiritual life enhances grit, optimism, and resilience while providing insulation against addiction, trauma, and depression. • The awakened life is the inspired life. Loss, uncertainty, and even trauma are the gateways by which we are invited to move beyond merely coping with hardship to transcend into a life of renewal, healing, joy, and fulfillment. Absorbing, uplifting, and ultimately enlightening, The Awakened Brain is a conversation-starting saga of scientific discovery packed with counterintuitive findings and practical advice on concrete ways to access your innate spirituality and build a life of meaning and contribution.

Science and the Quest for Meaning

Science and the Quest for Meaning PDF Author: Alfred I. Tauber
Publisher:
ISBN:
Category : Religion
Languages : en
Pages : 360

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Book Description
Packed with well-chosen case studies, Science and the Quest for Meaning is a trust-worthy and engaging introduction to the history of, and the current debate surrounding, the philosophy of science.--Jouni-Matti Kuukkanen, University of Hull "SciTech Book News"

The Genome Odyssey

The Genome Odyssey PDF Author: Dr. Euan Angus Ashley
Publisher: Celadon Books
ISBN: 1250234972
Category : Science
Languages : en
Pages : 221

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Book Description
In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human. In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome. These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.

Science and the Good

Science and the Good PDF Author: James Davison Hunter
Publisher: Yale University Press
ISBN: 0300196288
Category : Philosophy
Languages : en
Pages : 307

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Book Description
Why efforts to create a scientific basis of morality are neither scientific nor moral In this illuminating book, James Davison Hunter and Paul Nedelisky trace the origins and development of the centuries-long, passionate, but ultimately failed quest to discover a scientific foundation for morality. The "new moral science" led by such figures as E. O. Wilson, Patricia Churchland, Sam Harris, Jonathan Haidt, and Joshua Greene is only the newest manifestation of that quest. Though claims for its accomplishments are often wildly exaggerated, this new iteration has been no more successful than its predecessors. But rather than giving up in the face of this failure, the new moral science has taken a surprising turn. Whereas earlier efforts sought to demonstrate what is right and wrong, the new moral scientists have concluded, ironically, that right and wrong don't actually exist. Their (perhaps unwitting) moral nihilism turns the science of morality into a social engineering project. If there is nothing moral for science to discover, the science of morality becomes, at best, a feeble program to achieve arbitrary societal goals. Concise and rigorously argued, Science and the Good is a definitive critique of a would-be science that has gained extraordinary influence in public discourse today and an exposé of that project's darker turn.

The Second Kind of Impossible

The Second Kind of Impossible PDF Author: Paul Steinhardt
Publisher: Simon & Schuster
ISBN: 147672993X
Category : Science
Languages : en
Pages : 400

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Book Description
*Shortlisted for the 2019 Royal Society Insight Investment Science Book Prize* One of the most fascinating scientific detective stories of the last fifty years, an exciting quest for a new form of matter. “A riveting tale of derring-do” (Nature), this book reads like James Gleick’s Chaos combined with an Indiana Jones adventure. When leading Princeton physicist Paul Steinhardt began working in the 1980s, scientists thought they knew all the conceivable forms of matter. The Second Kind of Impossible is the story of Steinhardt’s thirty-five-year-long quest to challenge conventional wisdom. It begins with a curious geometric pattern that inspires two theoretical physicists to propose a radically new type of matter—one that raises the possibility of new materials with never before seen properties, but that violates laws set in stone for centuries. Steinhardt dubs this new form of matter “quasicrystal.” The rest of the scientific community calls it simply impossible. The Second Kind of Impossible captures Steinhardt’s scientific odyssey as it unfolds over decades, first to prove viability, and then to pursue his wildest conjecture—that nature made quasicrystals long before humans discovered them. Along the way, his team encounters clandestine collectors, corrupt scientists, secret diaries, international smugglers, and KGB agents. Their quest culminates in a daring expedition to a distant corner of the Earth, in pursuit of tiny fragments of a meteorite forged at the birth of the solar system. Steinhardt’s discoveries chart a new direction in science. They not only change our ideas about patterns and matter, but also reveal new truths about the processes that shaped our solar system. The underlying science is important, simple, and beautiful—and Steinhardt’s firsthand account is “packed with discovery, disappointment, exhilaration, and persistence...This book is a front-row seat to history as it is made” (Nature).

Life Science Quest for Middle Grades, Grades 6 - 8

Life Science Quest for Middle Grades, Grades 6 - 8 PDF Author: Schyrlet Cameron
Publisher: Mark Twain Media
ISBN: 1580377068
Category : Juvenile Nonfiction
Languages : en
Pages : 99

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Book Description
Connect students in grades 6–8 with science using Life Science Quest for Middle Grades. This 96-page book helps students practice scientific techniques while studying cells, plants, animals, DNA, heredity, ecosystems, and biomes. The activities use common classroom materials and are perfect for individual, team, and whole-group projects. The book includes a glossary, standards lists, unit overviews, and enrichment suggestions. It is great as core curriculum or a supplement and supports National Science Education Standards.

Science and the Quest for Reality

Science and the Quest for Reality PDF Author: Alfred I. Tauber
Publisher: Springer
ISBN: 1349252492
Category : Social Science
Languages : en
Pages : 431

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Book Description
Science and the Quest for Reality is an interdisciplinary anthology that situates contemporary science within its complex philosophical, historical, and sociological contexts. The anthology is divided between, firstly, characterizing science as an intellectual activity and, secondly, defining its social role. The philosophical and historical vicissitudes of science's truth claims has raised profound questions concerning the role of science in society beyond its technological innovations. The deeper philosophical issues thus complement the critical inquiry concerning the broader social and ethical influence of contemporary science. In the tradition of the 'Main Trends of the Modern World' series, this volume includes both classical and contemporary works on the subject.

The Professional Quest for Truth

The Professional Quest for Truth PDF Author: Stephan Fuchs
Publisher: SUNY Press
ISBN: 9780791409237
Category : Social Science
Languages : en
Pages : 280

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Book Description
This book argues that the power of science as the most respected and authoritative world view is based on its superior material and organizational resources, not on its superior rationality. Fuchs approaches science as a social construct, and utilizing a theory of scientific organizations, he analyzes knowledge production in scientific fields--how they differ in their resources and how these differences affect how science is conducted. The book explains why certain fields produce science and facts, while others engage in hermeneutics and conversation; why certain specialities change through cumulation rather than fragmentation; and why some fields are relativistic while others are positivist in their self-understanding. This general theory of knowledge is applicable not only to science, but to all varieties of professional groups engaged in knowledge production.