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Author: Dmitry A. Kondrashov
Publisher: University of Chicago Press
ISBN: 022637193X
Category : Science
Languages : en
Pages : 434
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Book Description
Since the time of Isaac Newton, physicists have used mathematics to describe the behavior of matter of all sizes, from subatomic particles to galaxies. In the past three decades, as advances in molecular biology have produced an avalanche of data, computational and mathematical techniques have also become necessary tools in the arsenal of biologists. But while quantitative approaches are now providing fundamental insights into biological systems, the college curriculum for biologists has not caught up, and most biology majors are never exposed to the computational and probabilistic mathematical approaches that dominate in biological research. With Quantifying Life, Dmitry A. Kondrashov offers an accessible introduction to the breadth of mathematical modeling used in biology today. Assuming only a foundation in high school mathematics, Quantifying Life takes an innovative computational approach to developing mathematical skills and intuition. Through lessons illustrated with copious examples, mathematical and programming exercises, literature discussion questions, and computational projects of various degrees of difficulty, students build and analyze models based on current research papers and learn to implement them in the R programming language. This interplay of mathematical ideas, systematically developed programming skills, and a broad selection of biological research topics makes Quantifying Life an invaluable guide for seasoned life scientists and the next generation of biologists alike.
Author: Dmitry A. Kondrashov
Publisher: University of Chicago Press
ISBN: 022637193X
Category : Science
Languages : en
Pages : 434
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Book Description
Since the time of Isaac Newton, physicists have used mathematics to describe the behavior of matter of all sizes, from subatomic particles to galaxies. In the past three decades, as advances in molecular biology have produced an avalanche of data, computational and mathematical techniques have also become necessary tools in the arsenal of biologists. But while quantitative approaches are now providing fundamental insights into biological systems, the college curriculum for biologists has not caught up, and most biology majors are never exposed to the computational and probabilistic mathematical approaches that dominate in biological research. With Quantifying Life, Dmitry A. Kondrashov offers an accessible introduction to the breadth of mathematical modeling used in biology today. Assuming only a foundation in high school mathematics, Quantifying Life takes an innovative computational approach to developing mathematical skills and intuition. Through lessons illustrated with copious examples, mathematical and programming exercises, literature discussion questions, and computational projects of various degrees of difficulty, students build and analyze models based on current research papers and learn to implement them in the R programming language. This interplay of mathematical ideas, systematically developed programming skills, and a broad selection of biological research topics makes Quantifying Life an invaluable guide for seasoned life scientists and the next generation of biologists alike.
Author: Katarzyna Wac
Publisher: Springer Nature
ISBN: 3030942120
Category : Bioinformatics
Languages : en
Pages : 596
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Book Description
Describes technological methods and tools for objective and quantitative assessment of QoL Appraises technology-enabled methods for incorporating QoL measurements in medicine Highlights the success factors for adoption and scaling of technology-enabled methods This open access book presents the rise of technology-enabled methods and tools for objective, quantitative assessment of Quality of Life (QoL), while following the WHOQOL model. It is an in-depth resource describing and examining state-of-the-art, minimally obtrusive, ubiquitous technologies. Highlighting the required factors for adoption and scaling of technology-enabled methods and tools for QoL assessment, it also describes how these technologies can be leveraged for behavior change, disease prevention, health management and long-term QoL enhancement in populations at large. Quantifying Quality of Life: Incorporating Daily Life into Medicine fills a gap in the field of QoL by providing assessment methods, techniques and tools. These assessments differ from the current methods that are now mostly infrequent, subjective, qualitative, memory-based, context-poor and sparse. Therefore, it is an ideal resource for physicians, physicians in training, software and hardware developers, computer scientists, data scientists, behavioural scientists, entrepreneurs, healthcare leaders and administrators who are seeking an up-to-date resource on this subject.
Author: Clayton M. Christensen
Publisher: Harvard Business Review Press
ISBN: 1633692574
Category : Business & Economics
Languages : en
Pages : 28
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Book Description
In the spring of 2010, Harvard Business School’s graduating class asked HBS professor Clay Christensen to address them—but not on how to apply his principles and thinking to their post-HBS careers. The students wanted to know how to apply his wisdom to their personal lives. He shared with them a set of guidelines that have helped him find meaning in his own life, which led to this now-classic article. Although Christensen’s thinking is rooted in his deep religious faith, these are strategies anyone can use. Since 1922, Harvard Business Review has been a leading source of breakthrough ideas in management practice. The Harvard Business Review Classics series now offers you the opportunity to make these seminal pieces a part of your permanent management library. Each highly readable volume contains a groundbreaking idea that continues to shape best practices and inspire countless managers around the world.
Author: Martha Lampland
Publisher: Cornell University Press
ISBN: 9780801474613
Category : Business & Economics
Languages : en
Pages : 268
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Book Description
Standardization is one of the defining aspects of modern life, its presence so pervasive that it is usually taken for granted. However cumbersome, onerous, or simply puzzling certain standards may be, their fundamental purpose in streamlining procedures, regulating behaviors, and predicting results is rarely questioned. Indeed, the invisibility of infrastructure and the imperative of standardizing processes signify their absolute necessity. Increasingly, however, social scientists are beginning to examine the origins and effects of the standards that underpin the technology and practices of everyday life.Standards and Their Stories explores how we interact with the network of standards that shape our lives in ways both obvious and invisible. The main chapters analyze standardization in biomedical research, government bureaucracies, the insurance industry, labor markets, and computer technology, providing detailed accounts of the invention of "standard humans" for medical testing and life insurance actuarial tables, the imposition of chronological age as a biographical determinant, the accepted means of determining labor productivity, the creation of international standards for the preservation and access of metadata, and the global consequences of "ASCII imperialism" and the use of English as the lingua franca of the Internet.Accompanying these in-depth critiques are a series of examples that depict an almost infinite variety of standards, from the controversies surrounding the European Union's supposed regulation of banana curvature to the minimum health requirements for immigrants at Ellis Island, conflicting (and ever-increasing) food portion sizes, and the impact of standardized punishment metrics like "Three Strikes" laws. The volume begins with a pioneering essay from Susan Leigh Star and Martha Lampland on the nature of standards in everyday life that brings together strands from the several fields represented in the book. In an appendix, the editors provide a guide for teaching courses in this emerging interdisciplinary field, which they term "infrastructure studies," making Standards and Their Stories ideal for scholars, students, and those curious about why coffins are becoming wider, for instance, or why the Financial Accounting Standards Board refused to classify September 11 as an "extraordinary" event.
Author: Jacqueline Wernimont
Publisher: MIT Press
ISBN: 0262039044
Category : Social Science
Languages : en
Pages : 239
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Book Description
A feminist media history of quantification, uncovering the stories behind the tools and technologies we use to count, measure, and weigh our lives and realities. Anglo-American culture has used media to measure and quantify lives for centuries. Historical journal entries map the details of everyday life, while death registers put numbers to life's endings. Today we count our daily steps with fitness trackers and quantify births and deaths with digitized data. How are these present-day methods for measuring ourselves similar to those used in the past? In this book, Jacqueline Wernimont presents a new media history of western quantification, uncovering the stories behind the tools and technologies we use to count, measure, and weigh our lives and realities. Numbered Lives is the first book of its kind, a feminist media history that maps connections not only between past and present-day “quantum media” but between media tracking and long-standing systemic inequalities. Wernimont explores the history of the pedometer, mortality statistics, and the census in England and the United States to illuminate the entanglement of Anglo-American quantification with religious, imperial, and patriarchal paradigms. In Anglo-American culture, Wernimont argues, counting life and counting death are sides of the same coin—one that has always been used to render statistics of life and death more valuable to corporate and state organizations. Numbered Lives enumerates our shared media history, helping us understand our digital culture and inheritance.
Author: Sally Engle Merry
Publisher: University of Chicago Press
ISBN: 022626131X
Category : Social Science
Languages : en
Pages : 260
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Book Description
We live in a world where seemingly everything can be measured. We rely on indicators to translate social phenomena into simple, quantified terms, which in turn can be used to guide individuals, organizations, and governments in establishing policy. Yet counting things requires finding a way to make them comparable. And in the process of translating the confusion of social life into neat categories, we inevitably strip it of context and meaning—and risk hiding or distorting as much as we reveal. With The Seductions of Quantification, leading legal anthropologist Sally Engle Merry investigates the techniques by which information is gathered and analyzed in the production of global indicators on human rights, gender violence, and sex trafficking. Although such numbers convey an aura of objective truth and scientific validity, Merry argues persuasively that measurement systems constitute a form of power by incorporating theories about social change in their design but rarely explicitly acknowledging them. For instance, the US State Department’s Trafficking in Persons Report, which ranks countries in terms of their compliance with antitrafficking activities, assumes that prosecuting traffickers as criminals is an effective corrective strategy—overlooking cultures where women and children are frequently sold by their own families. As Merry shows, indicators are indeed seductive in their promise of providing concrete knowledge about how the world works, but they are implemented most successfully when paired with context-rich qualitative accounts grounded in local knowledge.
Author: Peter J. Neumann
Publisher: Oxford University Press
ISBN: 0197512909
Category : Medical
Languages : en
Pages : 312
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Book Description
The US prescription drug business is a $500 billion industry whose rising prices carry profound consequences for patients, caregivers, employers and taxpayers across the nation. In the United States, average prices of leading brand-name drugs are two to four times higher than prices charged in other wealthy countries, raising questions as to what Americans are getting for the extra expense. On the other hand, healthy industry returns have arguably fueled life-saving innovation. With the advent of ever more targeted and powerful treatments, including cell- and gene-based therapies with multi-million-dollar price tags, the need for sensible drug pricing policies will only intensify. The Right Price sheds light on the controversial topic of drug pricing by providing an accessible guide to pharmaceutical markets and analytic techniques used to measure the value of drug therapies. It illustrates the need for value-based pricing through real-life stories of patients and their experiences with the drug industry and explains why simple solutions like price controls and the importation of cheaper drugs from other countries are problematic. This volume describes how researchers and policy makers have pursued drug valuation efforts in the past, and lays out a series of recommendations, based on years of shared author experience serving on national drug policy platforms, for how to further improve pharmaceutical value assessment in the United States. With unique industry insights and clear narrative, The Right Price unveils why the pricing of drugs continues to be so challenging and how public and private officials can create more informed policies to achieve the right balance between drug pricing and value.
Author: Deborah Lupton
Publisher: John Wiley & Sons
ISBN: 1509500634
Category : Social Science
Languages : en
Pages : 240
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Book Description
With the advent of digital devices and software, self-tracking practices have gained new adherents and have spread into a wide array of social domains. The Quantified Self movement has emerged to promote 'self-knowledge through numbers'. In this groundbreaking book Deborah Lupton critically analyses the social, cultural and political dimensions of contemporary self-tracking and identifies the concepts of selfhood and human embodiment and the value of the data that underpin them. The book incorporates discussion of the consolations and frustrations of self-tracking, as well as about the proliferating ways in which people's personal data are now used beyond their private rationales. Lupton outlines how the information that is generated through self-tracking is taken up and repurposed for commercial, governmental, managerial and research purposes. In the relationship between personal data practices and big data politics, the implications of self-tracking are becoming ever more crucial.
Author: Mark Batterson
Publisher: Multnomah
ISBN: 0593192788
Category : Religion
Languages : en
Pages : 257
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Book Description
The New York Times bestselling author of Chase the Lion reveals seven powerful habits that can help you tackle God-sized goals by turning yesterday’s regrets and tomorrow’s anxieties into fuel for a better today. “This book will change the trajectory of your life.”—John Maxwell, #1 New York Times bestselling author, entrepreneur, and leadership expert Too many people delay, downsize, or shrug off their dreams just because they don’t know where to start, but playing it safe doesn’t account for the massive cost of a life not fully lived. Win the Day is the jump-start you need to go after your goals, one day at a time. You’ll discover how to: 1. Flip the Script: If you want to change your life, start by changing your story. 2. Kiss the Wave: The obstacle is not the enemy; the obstacle is the way. 3. Eat the Frog: If you want God to do the super, you’ve got to do the natural. 4. Fly the Kite: How you do anything is how you’ll do everything. 5. Cut the Rope: Playing it safe is risky. 6. Wind the Clock: Time is measured in minutes; life is measured in moments. 7. Seed the Clouds: Sow today what you want to see tomorrow. As Batterson unpacks each of these daily habits, you’ll see how simple it is to pursue them with focus and dedication—not someday down the road, but now. Transform your perspective of a single day and you’ll discover the potential waiting to be grasped at the beginning of each new sunrise.
Author: Vaclav Smil
Publisher: MIT Press
ISBN: 0262539683
Category : Nature
Languages : en
Pages : 665
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Book Description
A systematic investigation of growth in nature and society, from tiny organisms to the trajectories of empires and civilizations. Growth has been both an unspoken and an explicit aim of our individual and collective striving. It governs the lives of microorganisms and galaxies; it shapes the capabilities of our extraordinarily large brains and the fortunes of our economies. Growth is manifested in annual increments of continental crust, a rising gross domestic product, a child's growth chart, the spread of cancerous cells. In this magisterial book, Vaclav Smil offers systematic investigation of growth in nature and society, from tiny organisms to the trajectories of empires and civilizations. Smil takes readers from bacterial invasions through animal metabolisms to megacities and the global economy. He begins with organisms whose mature sizes range from microscopic to enormous, looking at disease-causing microbes, the cultivation of staple crops, and human growth from infancy to adulthood. He examines the growth of energy conversions and man-made objects that enable economic activities—developments that have been essential to civilization. Finally, he looks at growth in complex systems, beginning with the growth of human populations and proceeding to the growth of cities. He considers the challenges of tracing the growth of empires and civilizations, explaining that we can chart the growth of organisms across individual and evolutionary time, but that the progress of societies and economies, not so linear, encompasses both decline and renewal. The trajectory of modern civilization, driven by competing imperatives of material growth and biospheric limits, Smil tells us, remains uncertain.
