Psychoses of the Schizophrenic Spectrum in Twins

Psychoses of the Schizophrenic Spectrum in Twins PDF Author: Ernst Franzek
Publisher: Springer Science & Business Media
ISBN: 3709163536
Category : Medical
Languages : en
Pages : 156

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Book Description
Contradictory results in schizophrenia research are generally explained as being due to genetic heterogeneity and multiple factor heredity in relationship to manifold environmental factors. The book reports a short overview of all relevant twin studies on schizophrenic psychoses and provides data and case histories on a systematic twin study based on a polydiagnostic approach carried out by two independently working psychiatrists. In addition to the internationally applied operational diagnostic systems of DSM-III-R and ICD 10 Leonhard’s subclassification of schizophrenic psychoses was used. Up to now this sophisticated methodological approach is unique in the world. The data provide strong evidence that the spectrum of psychoses with schizophrenic and schizophrenia-like symptoms is not a continuum of diseases. At least in Leonhard’s three major groups of cycloid psychoses, unsystematic schizophrenias and systematic schizophrenias genetic, somatic and psycho-social factors play a completely different etiological role. Cycloid psychoses and systematic schizophrenias are predominantly caused by "environmental” factors. In unsystematic schizophrenias, however, genetic predisposition is the main etiological factor and environmental factors are subordinate.

Psychoses of the Schizophrenic Spectrum in Twins

Psychoses of the Schizophrenic Spectrum in Twins PDF Author: Ernst Franzek
Publisher: Springer Science & Business Media
ISBN: 3709163536
Category : Medical
Languages : en
Pages : 156

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Book Description
Contradictory results in schizophrenia research are generally explained as being due to genetic heterogeneity and multiple factor heredity in relationship to manifold environmental factors. The book reports a short overview of all relevant twin studies on schizophrenic psychoses and provides data and case histories on a systematic twin study based on a polydiagnostic approach carried out by two independently working psychiatrists. In addition to the internationally applied operational diagnostic systems of DSM-III-R and ICD 10 Leonhard’s subclassification of schizophrenic psychoses was used. Up to now this sophisticated methodological approach is unique in the world. The data provide strong evidence that the spectrum of psychoses with schizophrenic and schizophrenia-like symptoms is not a continuum of diseases. At least in Leonhard’s three major groups of cycloid psychoses, unsystematic schizophrenias and systematic schizophrenias genetic, somatic and psycho-social factors play a completely different etiological role. Cycloid psychoses and systematic schizophrenias are predominantly caused by "environmental” factors. In unsystematic schizophrenias, however, genetic predisposition is the main etiological factor and environmental factors are subordinate.

Schizophrenia

Schizophrenia PDF Author: Irving I. Gottesman
Publisher: CUP Archive
ISBN: 9780521295598
Category : Medical
Languages : en
Pages : 276

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Book Description


Genetic and Environmental Factors in Schizophrenia

Genetic and Environmental Factors in Schizophrenia PDF Author: Margit Fischer
Publisher:
ISBN:
Category : Diseases in twins
Languages : en
Pages : 162

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Book Description


Divided Minds

Divided Minds PDF Author: Pamela Spiro Wagner
Publisher: Macmillan
ISBN: 9780312320652
Category : Biography & Autobiography
Languages : en
Pages : 346

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Book Description
Relates the stories of a pair of identical twin sisters, a schizophrenic and a psychiatrist, in an account that traces the deterioration of the favored sister into mental illness, and the other's emergence from her troubled sibling's shadow.

The Classification of Endogenous Psychoses

The Classification of Endogenous Psychoses PDF Author: Karl Leonhard
Publisher: de Gruyter
ISBN: 9783112706947
Category : Medical
Languages : en
Pages : 0

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Book Description
No detailed description available for "The Classification of Endogenous Psychoses".

Molecular Neuropathology

Molecular Neuropathology PDF Author: Gareth W. Roberts
Publisher: Cambridge University Press
ISBN: 9780521425582
Category : Medical
Languages : en
Pages : 204

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Book Description
This volume provides an introduction to the essential techniques required for studying the molecular biology of brain disease. The approaches and strategies for investigations of gene structure and regulation are described with reference to the molecular genetics of prion and Alzheimer's disease. The effects of aberrant gene regulation can also be examined at the protein level by immunocytochemistry and autoradiography. Improved understanding of basic biology has resulted in new approaches to animal models using transgenic techniques and new therapeutic approaches. The volume is structured to illustrate all these approaches and demonstrate the practice and promise of molecular neuropathology.

Genes and Behavior

Genes and Behavior PDF Author: Sir Michael Rutter
Publisher: Wiley-Blackwell
ISBN: 9781405110624
Category : Psychology
Languages : en
Pages : 272

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Book Description
In this major new book, eminent scientist Professor Sir Michael Rutter gets behind the hype of the behavioral genetics debate to provide a balanced and authoritative overview of the genetic revolution and its implications for understanding human behavior. Written by one of the world's leading figures in child psychology and psychiatry, Professor Sir Michael Rutter Provides non-technical explanation of genetics to diffuse the sensational debates surrounding the topic Sets out in layman's terms what genes do, how much is nature and how much is nurture Argues that nature and nurture are not truly separate and gives examples of how the two interact Looks at the implications of genetic findings for policy and practice The book will inform public debate about the implications of the Human Genome Project and, more broadly, the field of genetic science

Models of Madness

Models of Madness PDF Author: Dr John Read
Publisher: Routledge
ISBN: 1134055021
Category : Psychology
Languages : en
Pages : 489

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Book Description
Are hallucinations and delusions really symptoms of an illness called ‘schizophrenia’? Are mental health problems really caused by chemical imbalances and genetic predispositions? Are psychiatric drugs as effective and safe as the drug companies claim? Is madness preventable? This second edition of Models of Madness challenges those who hold to simplistic, pessimistic and often damaging theories and treatments of madness. In particular it challenges beliefs that madness can be explained without reference to social causes and challenges the excessive preoccupation with chemical imbalances and genetic predispositions as causes of human misery, including the conditions that are given the name 'schizophrenia'. This edition updates the now extensive body of research showing that hallucinations, delusions etc. are best understood as reactions to adverse life events and that psychological and social approaches to helping are more effective and far safer than psychiatric drugs and electroshock treatment. A new final chapter discusses why such a damaging ideology has come to dominate mental health and, most importantly, how to change that. Models of Madness is divided into three sections: Section One provides a history of madness, including examples of violence against the ‘mentally ill’, before critiquing the theories and treatments of contemporary biological psychiatry and documenting the corrupting influence of drug companies. Section Two summarises the research showing that hallucinations, delusions etc. are primarily caused by adverse life events (eg. parental loss, bullying, abuse and neglect in childhood, poverty, etc) and can be understood using psychological models ranging from cognitive to psychodynamic. Section Three presents the evidence for a range of effective psychological and social approaches to treatment, from cognitive and family therapy to primary prevention. This book brings together thirty-seven contributors from ten countries and a wide range of scientific disciplines. It provides an evidence-based, optimistic antidote to the pessimism of biological psychiatry. Models of Madness will be essential reading for all involved in mental health, including service users, family members, service managers, policy makers, nurses, clinical psychologists, psychiatrists, psychotherapists, counsellors, psychoanalysts, social workers, occupational therapists, art therapists.

Schizo-Obsessive Disorder

Schizo-Obsessive Disorder PDF Author: Michael Poyurovsky
Publisher: Cambridge University Press
ISBN: 1107000122
Category : Medical
Languages : en
Pages : 249

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Book Description
This is the first book to address the clinical and neurobiological interface between schizophrenia and obsessive-compulsive disorder (OCD). There is growing evidence that obsessive-compulsive symptoms in schizophrenia are prevalent, persistent and characterized by a distinct pattern of familial inheritance, neurocognitive deficits and brain activation. This text provides guidelines for differential diagnosis of schizophrenic patients with obsessive-compulsive symptoms, and patients with primary OCD alongside poor insight, psychotic features or schizotypal personality. Written by a leading expert in the coexistence of obsessive-compulsive and schizophrenic phenomena, Schizo-Obsessive Disorder uses numerous case studies to present diagnostic guidelines and to describe a recommended treatment algorithm, demystifying this complex disorder and aiding its effective management. The book is essential reading for psychiatrists, neurologists and the wider range of multidisciplinary mental health practitioners.

Cognitive Impairment in Schizophrenia

Cognitive Impairment in Schizophrenia PDF Author: Philip D. Harvey
Publisher: Cambridge University Press
ISBN: 1107013208
Category : Medical
Languages : en
Pages : 341

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Book Description
Provides state-of-the-art information about cognition in schizophrenia with a wide ranging focus on measuring and treating cognitive deficits.