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Author: Eric Denkers
Publisher: CRC Press
ISBN: 104019477X
Category : Science
Languages : en
Pages : 227
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Book Description
Using as a theme the encounter between protozoan parasites and macrophages, this volume brings together cell biologists, immunologists and protozoologists to review current developments in this broad and dynamic research area. Discussed are ways protozoans establish their intracellular niche, how they activate macrophage effector functions, what th
Author: Eric Denkers
Publisher: CRC Press
ISBN: 104019477X
Category : Science
Languages : en
Pages : 227
Get Book Here
Book Description
Using as a theme the encounter between protozoan parasites and macrophages, this volume brings together cell biologists, immunologists and protozoologists to review current developments in this broad and dynamic research area. Discussed are ways protozoans establish their intracellular niche, how they activate macrophage effector functions, what th
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Trypanosoma cruzi is a pathogenic protozoan of the Trypanosomatidade Family, which is the etiological agent of Chagas' disease. Chagas' disease stands out for being endemic among countries in Latin America, affecting about 15 million people. Recently, Chagas has become remarkable in European countries as well due to cases of transmission via infected blood transfusion. An important factor that has exacerbated the epidemiological picture in Brazil, Colombia and Venezuela is infection after the oral intake of contaminated foods such as sugar cane, açai and bacaba juices. Trypanosoma cruzi is an intracellular protozoan that exhibits a complex life cycle, involving multiple developmental stages found in both vertebrate and invertebrate hosts. In vertebrate hosts, the trypomastigote form invades a large variety of nucleated cells using multiple mechanisms. The invasion process involves several steps: (a) attraction of the protozoan to interact with the host cell surface; (b) parasite-host cell recognition; (c) adhesion of the parasite to the host cell surface; (d) cell signalling events that culminate in the internalization of the parasite through endocytic processes; (e) biogenesis of a large vacuole where the parasite is initially located, and is also known as parasitophorous vacuole (PV); (f) participation of endocytic pathway components in the internalization process; (g) participation of cytoskeleton components in the internalization process; (h) transformation of the trypomastigote into the amastigote form within the PV; (i) lysis of the membrane of the PV; (j) multiplication of amastigotes within the host cell in direct contact with cell structures and organelles; (k) transformation of amastigotes into trypomastigotes, and (l) rupture of the host cell releasing trypomastigotes into the extracellular space. The kinetics of the interaction process and even the fate of the parasite within the cell vary according to the nature of the host cell and its state of immunological activation.
Author: J M Behnke
Publisher: CRC Press
ISBN: 0850664993
Category : Science
Languages : en
Pages : 389
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Book Description
The topics of parasitism, parasite-induced pathology and relevant host response are interrelated, yet their interdependence is rarely appreciated. This collection of studies, illustrated by landmark experiments, emphasize this fundamental aspect of
Author: D. J. McKeever
Publisher: ILRI (aka ILCA and ILRAD)
ISBN: 9290552999
Category : Electronic books
Languages : en
Pages : 168
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Book Description
Author: Eric Denkers
Publisher: CRC Press
ISBN: 1498713041
Category : Science
Languages : en
Pages : 238
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Book Description
Using as a theme the encounter between protozoan parasites and macrophages, this volume brings together cell biologists, immunologists and protozoologists to review current developments in this broad and dynamic research area. Discussed are ways protozoans establish their intracellular niche, how they activate macrophage effector functions, what th
Author: Patsy Jenson
Publisher: CRC Press
ISBN: 1351090356
Category : Science
Languages : en
Pages : 529
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Book Description
It is the purpose of this book to make available to parasitologists and workers in many other disciplines a review of the developments leading up to the successful cultivation of the more important protozoan parasites of man and domestic animals. Included is a detailed description of the current state of the art protozoan parasite cultivation, and a limited discussion of the major achievements to our understanding of parasite biology derived through experimentation using cultured parasites.
Author: Ruth Porter
Publisher: John Wiley & Sons
ISBN: 0470717750
Category : Medical
Languages : en
Pages : 192
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Book Description
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Author: Mike Service
Publisher: Cambridge University Press
ISBN: 1107380227
Category : Science
Languages : en
Pages : 325
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Book Description
Despite numerous scientific investigations on vector-borne human infections such as malaria, Lyme disease and typhus these diseases continue to threaten human health. Understanding the role of vectors in disease transmission, and the most appropriate control strategies, is therefore essential. This book provides information on the recognition, biology, ecology and medical importance of the arthropods that affect human health. The fifth edition of this popular textbook is completely updated and incorporates the latest strategies for controlling insects, ticks and mites. Numerous illustrations, with new colour photographs of some of the most important vectors, aid recognition. A glossary of entomological and epidemiological terms is included, along with a list of commonly used insecticides and their trade names. Clearly presented in a concise style, this text is aimed at students of medical entomology, tropical medicine, parasitology and pest control. It is also essential reading for physicians, health officials and community health workers.
Author: John Marchalonis
Publisher: Springer Science & Business Media
ISBN: 1468445715
Category : Medical
Languages : en
Pages : 512
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Book Description
The phenomena involved in infections of man and domestic animals with metazoan or protozoan parasites present formidable practical problems as well as a theoretical challenge to immunologists, molecular biologists, and evolu tionary biologists. With respect to the public health and economic problems, malaria, for example, remains a major health problem with approximately 200 million people being infected yearly and, on the basis of World Health Organiza tion estimates, more than 1 million children die each year of malaria infections (Chapter 4). This volume addresses state-of-the-art immunologic approaches to the development of vaccines for parasitic diseases (Chapter 9) and analyses of studies bearing on the antigenic characterization of protozoan and metazoan parasites (Chapters 4, 5, and 7), on investigations of the role of precise mecha nisms underlying natural resistance or non permissiveness of the host to parasitic infections (Chapters 1, 2, and 12), on induced mechanisms including the genera tion of parasite-specific T-cell lines and clones (Chapter 6), and on the generation of monoclonal antibodies (Chapters 4 and 5) to parasite antigens of distinct de velopmental stages. Great progress has been made in characterizing parasite antigens capable of inducing a protective response in the vaccinated host; further progress in this area strongly depends on biochemistry and molecular biology with the long-term goal of synthesizing such antigens chemically or producing them by means of recombinant DNA technology (Chapter 4).
Author: Emilio Jirillo
Publisher: Bentham Science Publishers
ISBN: 160805148X
Category : Medical
Languages : en
Pages : 195
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Book Description
This Ebook provides an interesting and up-to-date overview of Parasite Immunology in terms of a survival battle between hosts and parasites, describing firstly how parasites interact with different B cell compartments and trigger a vigorous antibody response. An Interesting chapter deals with new insights into immune diagnosis in Trypanosoma cruzi infection, while another chapter on malaria vaccines critically reviews their development since the beginning, examining the basis for failures or successes encountered in clinical trials. Chapters on immunological aspects of amoebiasis, giardiasis.
