Proinflammatory and Antiinflammatory Peptides

Proinflammatory and Antiinflammatory Peptides PDF Author: Sami I. Said
Publisher: CRC Press
ISBN: 1000145999
Category : Medical
Languages : en
Pages : 760

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Book Description
"Analyzes the role of peptides in promoting or suppressing inflammation. Thoroughly examines the therapeutic potential of key peptides, analogs, agonists, and antagonists that influence cell injury and repair."

Proinflammatory and Antiinflammatory Peptides

Proinflammatory and Antiinflammatory Peptides PDF Author: Sami I. Said
Publisher: CRC Press
ISBN: 1000145999
Category : Medical
Languages : en
Pages : 760

Get Book Here

Book Description
"Analyzes the role of peptides in promoting or suppressing inflammation. Thoroughly examines the therapeutic potential of key peptides, analogs, agonists, and antagonists that influence cell injury and repair."

Proinflammatory and Antiinflammatory Peptides

Proinflammatory and Antiinflammatory Peptides PDF Author: Sami I. Said
Publisher: CRC Press
ISBN: 1000110141
Category : Medical
Languages : en
Pages : 756

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Book Description
"Analyzes the role of peptides in promoting or suppressing inflammation. Thoroughly examines the therapeutic potential of key peptides, analogs, agonists, and antagonists that influence cell injury and repair."

Novel Anti-inflammatory Peptides Based on Chemokines

Novel Anti-inflammatory Peptides Based on Chemokines PDF Author: Emily Francis McNaughton
Publisher:
ISBN:
Category :
Languages : en
Pages : 310

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Book Description


Structure-based Design of Anti-inflammatory Cyclic Peptides

Structure-based Design of Anti-inflammatory Cyclic Peptides PDF Author: Mohannad Idress
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology PDF Author: William B. Coleman
Publisher: Academic Press
ISBN: 0128132582
Category : Medical
Languages : en
Pages : 634

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Book Description
Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

Cytokines and Pain

Cytokines and Pain PDF Author: L.R. Watkins
Publisher: Springer
ISBN: 3034887493
Category : Medical
Languages : en
Pages : 248

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Book Description
Within the past few years, it has become recognized that the immune system communicates to the brain. Substances released from activated immune cells (cytokines) stimulate peripheral nerves, thereby signaling the brain and spinal cord that infection/inflammation has occurred. Additionally, peripheral infection/inflammation leads to de novo synthesis and release of cytokines within the brain and spinal cord. Thus, cytokines effect neural activation both peripherally and centrally. Through this communication pathway, cytokines such as interleukin-1, interleukin-6 and tumor necrosis factor markedly alter brain function, physiology and behavior. One important but underrecognized aspect of this communication is the dramatic impact that immune activation has on pain modulation. The purpose of this book is to examine, for the first time, immune-to-brain communication from the viewpoint of its effect on pain processing. It is aimed both at the basic scientist and health care providers, in order to clarify the major role that substances released by immune cells play in pain modulation. This book contains chapters contributed by all of the major laboratories focused on understanding how cytokines modulate pain. These chapters provide a unique vantage point from which to examine this question, as the summarized work ranges from evolutionary approaches across diverse species, to the basics of the immune response, to the effect of cytokines on peripheral and central nervous system sites, to therapeutic potential in humans.

Psychoneuroimmunology

Psychoneuroimmunology PDF Author: Robert Ader
Publisher: Academic Press
ISBN: 1483258904
Category : Medical
Languages : en
Pages : 1263

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Book Description
Psychoneuroimmunology, Second Edition presents reports on the relationship between the nervous and immune systems. The book is divided into four sections. The first section details the role of neural structures and neurotransmitter signals in communication with the immune system. It documents the extensive neural connections with organs of the immune system; the dynamics of noradrenergic sympathetic innervation of spleen and thymus; and the evidence for immune signaling of the CNS. Part II elaborates the role of hormones in the modulation of immune functions; the basis for bidirectional communication between the neuroendocrine and immune systems; and the potential physiological implications of these neuroendocrine-immune system interactions. The third part addresses behavioral influences on immune response; the effects of conditioning, stress and social interactions in modulating immune responses; and the behavioral consequences of experimentally altered or genetically determined immunologic states. The final section presents the effects of psychosocial factors on immune responses and the potential impact of behavioral interventions in modulating immunity in healthy human subjects and in patients with AIDS. Neuroscientists, endocrinologists, and immunologists will find the book interesting.

The Molecular Basis of Viral Infection

The Molecular Basis of Viral Infection PDF Author:
Publisher: Academic Press
ISBN: 0128025875
Category : Science
Languages : en
Pages : 468

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Book Description
Virology is in a sense both one of the most important precursors and one of the most significant beneficiaries of structural and cellular molecular biology. Numerous breakthroughs in our understanding of the molecular interactions of viruses with host cells are ready for translation into medically important applications such as the prevention and treatment of viral infections. This book collects a wide variety of examples of frontline research into molecular aspects of viral infections from virological, immunological, cell- and molecular-biological, structural, and theoretical perspectives. Contributors are world leaders in their fields of study and represent prestigious academic and research institutions Review articles vary vastly in scope: some focus on a narrowly defined scientific problem of one particular virus with careful introduction for the non-specialist; others are essays in general and comparative virology with forays into specific viral species or molecules The different perspectives complement each other and collectively the contributions provide an impression of the fast-moving frontlines of virology while showing how the problems have evolved Structural data are presented through high-quality illustrations

Wound Healing

Wound Healing PDF Author: Kursad Turksen
Publisher: John Wiley & Sons
ISBN: 1119282489
Category : Science
Languages : en
Pages : 320

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Book Description
A comprehensive resource on the recent developments of stem cell use in wound healing With contributions from experts in the field, Wound Healing offers a thorough review of the most recent findings on the use of stem cells to heal wounds. This important resource covers both the basic and translational aspects of the field. The contributors reveal the great progress that has been made in recent years and explore a wide range of topics from an overview of the stem cell process in wound repair to inflammation and cancer. They offer a better understanding of the identities of skin stem cells as well as the signals that govern their behavior that contributes to the development of improved therapies for scarring and poorly healing wounds. Comprehensive in scope, this authoritative resource covers a wealth of topics such as: an overview of stem cell regeneration and repair, wound healing and cutaneous wound healing, the role of bone marrow derived stems cells, inflammation in wound repair, role and function of inflammation in wound repair, and much more. This vital resource: Provides a comprehensive overview of stem cell use in wound healing, including both the basic and translational aspects of the field Covers recent developments and emerging subtopics within the field Offers an invaluable resource to clinical and basic researchers who are interested in wound healing, stem cells, and regenerative medicine Contains contributions from leading experts in the field of wound healing and care Wound Healing offers clinical researchers and academics a much-needed resource written by noted experts in the field that explores the role of stem cells in the repair and restoration of healing wounds.

Antimicrobial Peptides

Antimicrobial Peptides PDF Author: Katsumi Matsuzaki
Publisher: Springer
ISBN: 9811335885
Category : Medical
Languages : en
Pages : 304

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Book Description
This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.