Prognostic and Predictive Factors in Breast Cancer PDF Download
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Author: Rosemary A. Walker
Publisher: CRC Press
ISBN: 1040204651
Category : Medical
Languages : en
Pages : 205
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Book Description
This title reviews the key prognostic factors in breast cancer, discussing the methodologies involved in measuring and reporting. It also examines the roles of major predictive markers such as the steroid receptors, p53 and HER-2. Given the wealth of information in the medical literature on breast cancer, this volume is useful in that it focuses st
Author: Rosemary A. Walker
Publisher: CRC Press
ISBN: 1040204651
Category : Medical
Languages : en
Pages : 205
Get Book Here
Book Description
This title reviews the key prognostic factors in breast cancer, discussing the methodologies involved in measuring and reporting. It also examines the roles of major predictive markers such as the steroid receptors, p53 and HER-2. Given the wealth of information in the medical literature on breast cancer, this volume is useful in that it focuses st
Author: Henry Kuerer
Publisher: McGraw Hill Professional
ISBN: 0071601775
Category : Medical
Languages : en
Pages : 1178
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Book Description
A complete multidisciplinary guide to breast surgical oncology Includes DVD with surgical video clips and breast ultrasound atlas A Doody's Core Title for 2011! A British Medical Association Book Awards Runner-up, Oncology category! "Kuerer's new textbook of Breast Surgical Oncology is a comprehensive volume that contains exceptionally detailed and thorough information about the diverse aspects of breast cancer care, and would serve as a valuable resource for any breast cancer clinician, regardless of their specialty. ... (the book) is easy to read and navigate, where clinicians can quickly obtain reliable, up-to-date information on a broad range of topics relevant to breast cancer. --Annals of Surgery, August 2010 4 STAR DOODY'S REVIEW! "...a comprehensive and authoritative synthesis of current information is sorely needed, and this book fulfills that need admirably....The figures (many in color) and tables reproduce beautifully. The chapters on ultrasound, clinical trials, and plastic surgery, are particularly valuable. This is a terrific and incredibly useful book on breast surgical oncology, and will be an important reference in the field."--Doody's Review Service Written by an internationally recognized multidisciplinary team of authors, Kuerer's Breast Surgical Oncology is the first text specifically dedicated to breast surgical oncology. Turn to any page, and you’ll find cutting-edge, evidence-based information and insights—supplemented by a full-color presentation and a companion DVD—all designed to help provide a solid foundation for current and future best practices. Kuerer's examines all clinically relevant knowledge in the field, from the pathology of the breast and clinical management, to follow-up and complications following diagnosis and therapy. The book also focuses on the next wave of molecular studies that represent the future of the discipline. Features Complete integration of the relevant disease pathology with clinical management Major sections on both oncoplastic and advanced operative management procedures An entire section on landmark breast cancer clinical trials that highlights essential knowledge and evidence in the field Full-color design with 750 illustrations that depict anatomy, breast cancer pathology, and trial results A DVD with surgical video clips that details some of the important surgical techniques and procedures featured in the text An entire section on breast imaging and an atlas on breast ultrasound and biopsy techniques that facilitate accurate diagnosis and treatment Timely, special chapter on the influence of the media and the internet on breast cancer care and the funding of breast cancer research A detailed overview of currently open and accruing clinical trials, along with the future critical questions that must be answered to move the field forward Coverage of molecular findings that provides an enhanced perspsective on the full spectrum of malignancies with which they work
Author: Giampietro Gasparini
Publisher: Springer Science & Business Media
ISBN: 159259915X
Category : Medical
Languages : en
Pages : 335
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Book Description
Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.
Author: Elizabeth H. Holt
Publisher: Academic Press
ISBN: 012815845X
Category : Medical
Languages : en
Pages : 554
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Book Description
Goodman's Basic Medical Endocrinology, Fifth Edition, has been student tested and approved for decades. This essential textbook provides up-to-date coverage of rapidly unfolding advances in the understanding of hormones involved in regulating most aspects of bodily functions. It is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study. - Clinical case studies in every chapter - E-book version available with every copy for obtaining images and tables for lectures or notes - Clinicians added as co-authors to enhance usefulness by physicians and medical students and residents - Detailed molecular biology of hormones and hormone action for graduate and advanced undergraduate students - Expanded and updated color images emphasizing hormone action at the molecular level - In-depth molecular biology and clinical sections boxed for ease of access
Author: Giampietro Gasparini
Publisher: Springer Science & Business Media
ISBN: 9780792384472
Category : Medical
Languages : en
Pages : 440
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Book Description
During the last decade, important advancements on the understanding of the molecular mechanisms involved in tumorigenesis and progression of breast cancer have been made, particularly regarding the mechanisms of control of the cell cycle, apoptosis, metastasis, and angiogenesis. Translation of basic research to the clinical setting by the identification of assessable markers associated with the above biological mechanisms has permitted verification of the clinical significance of several prognostic indicators and has highlighted the heterogeneous nature of invasive breast cancer.Reprinted from Breast Cancer Research And Treatment, this text contains original papers, overviews, and position papers on the methodological aspects and the clinical significance of the more interesting prognostic and predictive indicators. Ultimately, the determination of biological prognostic and predictive markers with easily applicable, reproducible, and standardizable assays is an integral part of future research aimed to improve the management of patients operated for breast cancer in the years to come. Novel therapeutic strategies based not only on chemotherapy or hormone therapy, but directed at interfering with the molecular targets involved in tumor progression and metastasis, warrant clinical testing and are a major challenge to enhance the potential cure of breast cancer.
Author: Monica Castiglione
Publisher: Springer Science & Business Media
ISBN: 0387751157
Category : Medical
Languages : en
Pages : 483
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Book Description
Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.
Author: Simona Stolnicu
Publisher: Springer
ISBN: 3319932578
Category : Medical
Languages : en
Pages : 510
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Book Description
This book presents the basic concepts for understanding and practicing breast pathology in routine practice. It explains how to tackle the diagnosis, emphasizing diagnostic clues for each entity as well as pitfalls and mimickers. Each chapter has concise, relevant text illustrated by numerous high-quality pictures highlighting the pearls and challenges in the diagnosis of breast lesions. Experts from around the world describe common and rarer conditions affecting the breast. Histology, immunohistochemistry, cytology, radiology and key morphologic criteria are covered. The book includes a chapter dedicated to breast normal histology, which is very important for understanding breast pathology, and a separate chapter for breast radiology, which is essential in understanding and diagnosing the breast lesions especially in a multidisciplinary team. Also, there is a chapter with the latest TNM staging system as well as the recently revised World Health Organization classification of breast tumors. Since in many breast units the cytology is still used to diagnose breast lesions there is a chapter dedicated to this technique. This book is aimed at trainees and practicing pathologists in surgical pathology, particularly those with an interest in breast pathology and those tackling the daily sign-out.
Author: Richard D. Riley
Publisher: Oxford University Press
ISBN: 0192516655
Category : Medical
Languages : en
Pages : 373
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Book Description
"What is going to happen to me?" Most patients ask this question during a clinical encounter with a health professional. As well as learning what problem they have (diagnosis) and what needs to be done about it (treatment), patients want to know about their future health and wellbeing (prognosis). Prognosis research can provide answers to this question and satisfy the need for individuals to understand the possible outcomes of their condition, with and without treatment. Central to modern medical practise, the topic of prognosis is the basis of decision making in healthcare and policy development. It translates basic and clinical science into practical care for patients and populations. Prognosis Research in Healthcare: Concepts, Methods and Impact provides a comprehensive overview of the field of prognosis and prognosis research and gives a global perspective on how prognosis research and prognostic information can improve the outcomes of healthcare. It details how to design, carry out, analyse and report prognosis studies, and how prognostic information can be the basis for tailored, personalised healthcare. In particular, the book discusses how information about the characteristics of people, their health, and environment can be used to predict an individual's future health. Prognosis Research in Healthcare: Concepts, Methods and Impact, addresses all types of prognosis research and provides a practical step-by-step guide to undertaking and interpreting prognosis research studies, ideal for medical students, health researchers, healthcare professionals and methodologists, as well as for guideline and policy makers in healthcare wishing to learn more about the field of prognosis.
Author: National Cancer Institute (U.S.)
Publisher:
ISBN:
Category : African Americans
Languages : en
Pages : 288
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Book Description
Author: Sudhir Srivastava
Publisher: John Wiley & Sons
ISBN: 1118468805
Category : Medical
Languages : en
Pages : 334
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Book Description
Prepared by world leaders on this topic, Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and use in developing personalized cancer treatment. Offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers Provides immediately actionable information – and hopefully also inspiration – to move discovery and clinical application forward Offers vital knowledge to help develop personalized cancer treatment for individual patients with specific cancers
