Proceedings of the Symposium on the Use of Athymic (Nude) Mice in Cancer Research, Battelle Memorial Institute, Columbus, Ohio, June 15-16, 1977 PDF Download
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Author: David P. Houchens
Publisher: Fischer Gustav Verlag GmbH & Company KG
ISBN:
Category : Medical
Languages : en
Pages : 326
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Book Description
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1174
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Book Description
First multi-year cumulation covers six years: 1965-70.
Author: David P. Houchens
Publisher: Fischer Gustav Verlag GmbH & Company KG
ISBN:
Category : Medical
Languages : en
Pages : 326
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Book Description
Author: S. Sparrow
Publisher: Springer
ISBN: 1349050148
Category : Medical
Languages : en
Pages : 245
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Book Description
Author: National Cancer Institute (U.S.). Division of Cancer Treatment
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 690
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Author: Beverly A. Teicher
Publisher: Springer Science & Business Media
ISBN: 1461581524
Category : Medical
Languages : en
Pages : 315
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Book Description
Experienced cancer researchers from pharmaceutical companies, government laboratories, and academia comprehensively review and describe the arduous process of cancer drug discovery and approval. They focus on using preclinical in vivo and in vitro methods to identify molecules of interest, detailing the targets and criteria for success in each type of testing and defining the value of the information obtained from the various tests. They also define each stage of clinical testing, explain the criteria for success, and outline the requirements for FDA approval. A companion volume by the same editor (Cancer Therapeutics: Experimental and Clinical Agents) reviews existing anticancer drugs and potential anticancer therapies. These two volumes in the Cancer Drug Discovery and Development series reveal how and why molecules become anticancer drugs and thus offer a blueprint for the present and the future of the field.
Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 746
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Author: Beverly A. Teicher
Publisher: Springer Science & Business Media
ISBN: 1592591000
Category : Medical
Languages : en
Pages : 745
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Book Description
Beverly A. Teicher and a panel of leading experts comprehensively describe for the first time in many years the state-of-the-art in animal tumor model research. The wide array of models detailed form the basis for the selection of compounds and treatments that go into clinical testing of patients, and include syngeneic models, human tumor xenograft models, orthotopic models, metastatic models, transgenic models, and gene knockout models. Synthesizing many years experience with all the major in vivo models currently available for the study of malignant disease, Tumor Models in Cancer Research provides preclinical and clinical cancer researchers alike with a comprehensive guide to the selection of these models, their effective use, and the optimal interpretation of their results.
Author: M. Eric Gershwin
Publisher: Springer Science & Business Media
ISBN: 1475703252
Category : Medical
Languages : en
Pages : 365
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Book Description
Tiselius demonstrated that the immunologically active components of immune sera migrated electrophoretically in the gamma globulin region. His findings illuminated the classic observations of Jenner regarding development of resistance to infection, and those of von Pirquet, Pasteur, and Arthus regarding the transfer and specificity of resistance. Conceptual integration of these observations provided the impetus for the present modern era of immunology. Subsequent to Tiselius's work, multiple, rapid advances have occurred in the study of congenital and acquired immune deficiency states in mice, chickens, and humans. These studies have readily demonstrated that the immunologic ability of an organ ism to protect itself from environmental influences is a prerequisite for survival. Indeed, this necessity for protection from microenvironmental influences has promoted the evolu tionary development of immunologic diversification, namely, host dependence upon a sophisticated, multifaceted network of cells and effector mechanisms responsible for the clearance and neutralization of toxins and potentially harmful pathogens. The obligate dependence of animals upon the functional integrity of their immunologic systems is illus trated by the ready invasion of ubiquitous organisms when the host is in a state of immune defense derangement. Nevertheless, derangements in immune function can range from par tial to complete and can be compatible with survival. The consequences of such derange ments run the gamut from subclinical disease to inevitable mortality.
Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 662
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Book Description
Author: Norman D. Reed
Publisher: Fischer Gustav Verlag GmbH & Company KG
ISBN:
Category : Communicable diseases
Languages : en
Pages : 360
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Book Description
