Proceedings of the International Symposium on Laboratory Automation and Robotics 1995

Proceedings of the International Symposium on Laboratory Automation and Robotics 1995 PDF Author: James N. Little
Publisher:
ISBN: 9780931565137
Category : Automation
Languages : en
Pages : 688

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Book Description

Proceedings of the International Symposium on Laboratory Automation and Robotics 1995

Proceedings of the International Symposium on Laboratory Automation and Robotics 1995 PDF Author: James N. Little
Publisher:
ISBN: 9780931565137
Category : Automation
Languages : en
Pages : 688

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Book Description


Drug Discovery from Nature

Drug Discovery from Nature PDF Author: S. Grabley
Publisher: Springer Science & Business Media
ISBN: 9783540648444
Category : Medical
Languages : en
Pages : 380

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Book Description
This book is unique in covering the present status and future potential of natural products in drug discovery. It provides readers with recent information regarding the impact on drug discovery, development and strategies, technical and automation aspects, and methods based on biochemistry as well as molecular biology, highlighting compounds from natural sources. Special emphasis is placed on the various strategies to gain access to natural compounds and combinatorial approaches by making use of both synthetic and biological methods.

Handbook of Drug Screening

Handbook of Drug Screening PDF Author: Ramakrishna Seethala
Publisher: CRC Press
ISBN: 0824741447
Category : Medical
Languages : en
Pages : 619

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Book Description
A presentation of screening techniques, modern technologies, and high-capacity instrumentation for increased productivity in the development and discovery of new drugs, chemical compounds, and targeted delivery of pharmaceuticals. It contains practical applications and examples of strategies in cell-based and cell-free screens as well as homogeneous, fluorescence, chemiluminescence, and radioactive-based technologies.

Index of Conference Proceedings

Index of Conference Proceedings PDF Author: British Library. Document Supply Centre
Publisher:
ISBN:
Category : Conference proceedings
Languages : en
Pages : 870

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Book Description


Handbook of Radiopharmaceuticals

Handbook of Radiopharmaceuticals PDF Author: Michael J. Welch
Publisher: John Wiley & Sons
ISBN: 9780471495604
Category : Medical
Languages : en
Pages : 872

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Book Description
A comprehensive, authoritative and up-to-date reference for the newcomer to radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to detect and characterise disease processes, or normal biological function, in living cells, animals or humans. Used as tracer molecules, they map the distribution, uptake and metabolism of the molecule in clinical studies, basic research or applied research. The area of radiopharmaceuticals is expanding rapidly. The number of PET centers in the world is increasing at 20% per year, and many drug companies are utilising PET and other forms of radiopharmaceutical imaging to evaluate products. * Readers will find coverage on a number of important topics such as radionuclide production, PET and drug development, and regulations * Explains how to use radiopharmaceuticals for the diagnosis and therapy of cancer and other diseases * The editors and a majority of the contributors are from the United States

Thermal Biosensors Bioactivity Bioaffinity

Thermal Biosensors Bioactivity Bioaffinity PDF Author: Thomas Scheper
Publisher: Springer
ISBN: 3540498117
Category : Science
Languages : en
Pages : 243

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Book Description
The immobilized biocatalyst (IMB) is a key component of biotransformation systems that are used to transform substrates to desired products. The impro- ment of biocatalyst properties has a direct influence on the overall effectiveness of the process based on the biotransformation. The basic catalytic characte- stics of biocatalyst that are followed include kinetic properties, pH optima, stability, and inhibition. The investigation of catalytic properties of immobilized enzymes is still a time consuming procedure and is not always simple. In the 1980s, a major effort was made to standardize the rules by which IMB is char- terized. The Working Party of EFB on immobilized biocatalysts has formul- ed principles of individual methods, among them the requirement of kinetic characterization [1]. It was recommended to use a packed-bed reactor, equipped with temperature control and with infinite flow circulation. The system should be equipped with a post-column unit to measure the time-dependence of the product or substrate concentration [2, 3], the most commonly used analytical methods being spectrophotometry, chemiluminiscence, automatic titration, bioluminiscence, chromatography, polarimetry, and biosensors based on the oxygen electrode. There are two main drawbacks to the application of these methods: 1. The need to vary the analytical principles, depending on the chemical and physical-chemical properties of analytes; 2. In some cases, mainly in the study of hydrolytic enzymes, the natural s- strate must be replaced by an artificial one, that is chromolytic, chromogenic, chemiluminiscent, bioluminiscent, or fluorescent.

Combinatorial Chemistry and Technologies

Combinatorial Chemistry and Technologies PDF Author: Stanislav Miertus
Publisher: CRC Press
ISBN: 0824758374
Category : Medical
Languages : en
Pages : 616

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Book Description
Several books on the market cover combinatorial techniques, but they offer just a limited perspective of the field, focusing on selected aspects without examining all approaches and integrated technologies. Combinatorial Chemistry and Technologies: Methods and Applications answers the demand for a complete overview of the field, covering all of the methodologies used in the design, synthesis, and screening of molecular libraries. Now in its second edition, this volume updates prior content and explores new areas such as catalysis, applications in biotechnology, and current ICS-UNIDO activities. Topics include the generation of molecular diversity by chemical methods using solution- and solid-phase chemistries, biological approaches for the production and screening of peptides, antibody and oligonucleotide libraries, and the application of computer-assisted approaches to guide library synthesis. The book establishes the link between combinatorial chemistry and molecular modeling and illustrates the importance of economics and patenting in combinatorial technologies. Valuable to technologists and researchers as an introductory survey on the many aspects of combinatorial chemistry and combinatorial technology, Combinatorial Chemistry and Technologies: Methods and Applications offers an overview of a field that promises broad applicability in the identification of new drugs, as well as in diagnostics, new materials, and catalysis.

Combinatorial Chemistry and Technology

Combinatorial Chemistry and Technology PDF Author: Stanislav Miertus
Publisher: CRC Press
ISBN: 9781420000566
Category : Science
Languages : en
Pages : 456

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Book Description
"Provides comprehensive coverage of the current combinatorial methodologies and technologies employed for the design, synthesis, and screening of molecular ""libraries."" Features assessments of computer-assisted approaches to guiding library synthesis. Designed to satisfy the demand to create, produce in high yield and purity, and rapidly screen huge numbers of molecules."

Robotics Research

Robotics Research PDF Author: Georges Giralt
Publisher: Springer Science & Business Media
ISBN: 1447110218
Category : Technology & Engineering
Languages : en
Pages : 650

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Book Description
This publication covers all the topics which are relevant to Advanced Robotics today, ranging from Systems Design to Reasoning and Planning. It is based on the Seventh International Symposium on Robotics Research held in Germany on October, 21 - 24th, 1995. The papers were written by specialists in the field from the United States, Europe, Japan, Australia and Canada. The editors, who also chaired this symposium, present the latest research results as well as new approaches to long standing problems. Robotics Research is a contribution to the emerging concepts, methods and tools that shape Robotics. The papers range from pure research reports to application-oriented studies. The topics covered include: manipulation, control, virtual reality, motion planning, 3D vision and industrial systems' issues.

High Throughput Screening

High Throughput Screening PDF Author: John P. Devlin
Publisher: CRC Press
ISBN: 9780824700676
Category : Science
Languages : en
Pages : 704

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Book Description
Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high throughput screening (HTS) systems and provides a solid foundation for the implementation and development of HTS in bio-based industries and associated academic environments.