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Author: Sanjay Patole
Publisher: Springer
ISBN: 9783030719234
Category : Medical
Languages : en
Pages : 188
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Book Description
Evidence based medicine is at the core of modern medicine. It involves the integration of individual clinical expertise with the best available clinical evidence from systematic research and patient's values and expectations. Systematic reviews offer a summary of the best available evidence. They are the most reliable and comprehensive statement about what works. Written by clinical academics from Australia, UK, USA, and Switzerland, this contributed volume introduces the readers to the principles and practice of systematic reviews and meta-analysis. It covers the various steps involved in systematic reviews including development of a focused question and the strategy for conducting a comprehensive literature search, identifying studies addressing the underlying question, assessment of heterogeneity and the risk of bias in the included studies, data extraction, and the approach to meta-analysis. Crucial issues such as selecting the model for meta-analysis, generating and interpreting forest plots, assessing the risk of publication bias, cautions in the interpretation of subgroup and sensitivity analyses, rating certainty of the evidence using GRADE guideline, and standardized reporting of meta-analysis (PRISMA) are covered in detail. Every attempt is made to keep the narrative simple and clear. Mathematical formulae are avoided as much as possible. While the focus of this book is on systematic reviews and meta-analyses of randomised controlled trials (RCTs), the gold standard of clinical research, the essentials of systematic reviews of non-RCTs, diagnostic test accuracy studies, animal studies, individual participant data meta-analysis, and network meta-analysis are also covered. Readers from all faculties of medicine will enjoy this comprehensive and reader friendly book to understand the principles and practice of systematic reviews and meta-analysis for guiding their clinical practice and research.
Author: Sanjay Patole
Publisher: Springer
ISBN: 9783030719234
Category : Medical
Languages : en
Pages : 188
Get Book Here
Book Description
Evidence based medicine is at the core of modern medicine. It involves the integration of individual clinical expertise with the best available clinical evidence from systematic research and patient's values and expectations. Systematic reviews offer a summary of the best available evidence. They are the most reliable and comprehensive statement about what works. Written by clinical academics from Australia, UK, USA, and Switzerland, this contributed volume introduces the readers to the principles and practice of systematic reviews and meta-analysis. It covers the various steps involved in systematic reviews including development of a focused question and the strategy for conducting a comprehensive literature search, identifying studies addressing the underlying question, assessment of heterogeneity and the risk of bias in the included studies, data extraction, and the approach to meta-analysis. Crucial issues such as selecting the model for meta-analysis, generating and interpreting forest plots, assessing the risk of publication bias, cautions in the interpretation of subgroup and sensitivity analyses, rating certainty of the evidence using GRADE guideline, and standardized reporting of meta-analysis (PRISMA) are covered in detail. Every attempt is made to keep the narrative simple and clear. Mathematical formulae are avoided as much as possible. While the focus of this book is on systematic reviews and meta-analyses of randomised controlled trials (RCTs), the gold standard of clinical research, the essentials of systematic reviews of non-RCTs, diagnostic test accuracy studies, animal studies, individual participant data meta-analysis, and network meta-analysis are also covered. Readers from all faculties of medicine will enjoy this comprehensive and reader friendly book to understand the principles and practice of systematic reviews and meta-analysis for guiding their clinical practice and research.
Author: Matthias Egger
Publisher: John Wiley & Sons
ISBN: 0470693142
Category : Medical
Languages : en
Pages : 512
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Book Description
The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.
Author: Julian P. T. Higgins
Publisher: Wiley
ISBN: 9780470699515
Category : Medical
Languages : en
Pages : 672
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Book Description
Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.
Author: Jacqueline Corcoran
Publisher: Oxford University Press
ISBN: 0199716862
Category : Social Science
Languages : en
Pages : 211
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Book Description
When used in tandem, systematic reviews and meta-analysis-- two distinct but highly compatible approaches to research synthesis-- form a powerful, scientific approach to analyzing previous studies. But to see their full potential, a social work researcher must be versed in the foundational processes underlying them. This pocket guide to Systematic Reviews and Meta-Analysis illuminates precisely that practical groundwork. In clear, step-by-step terms, the authors explain how to format topics, locate and screen studies, extract and assess data, pool effect sizes, determine bias, and interpret the results, showing readers how to combine reviewing and meta-analysis correctly and effectively. Each chapter contains vivid social work examples and concludes with a concise summary and notes on further reading, while the book's glossary and handy checklists and sample search and data extraction forms maximize the boo'ks usefulness. Highlighting the concepts necessary to understand, critique, and conduct research synthesis, this brief and highly readable introduction is a terrific resource for students and researchers alike.
Author: Matthias Egger
Publisher: John Wiley & Sons
ISBN: 1405160500
Category : Medical
Languages : en
Pages : 612
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Book Description
Systematic Reviews in Health Research Explore the cutting-edge of systematic reviews in healthcare In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including: Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysis Thorough update of 15 chapters focusing on systematic reviews of interventions Access to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org) A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis.
Author: David Gough
Publisher: SAGE
ISBN: 1446289362
Category : Literary Criticism
Languages : en
Pages : 382
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Book Description
This timely, engaging book provides an overview of the nature, logic, diversity and process of undertaking systematic reviews as part of evidence informed decision making. A focused, accessible and technically up-to-date book, it covers the full breadth of approaches to reviews from statistical meta analysis to meta ethnography. It is ideal for anyone undertaking their own systematic review - providing all the necessary conceptual and technical background needed to make a good start on the process. The content is divided into five clear sections: • Approaches to reviewing • Getting started • Gathering and describing research • Appraising and synthesising data • Making use of reviews/models of research use. Easy to read and logically structured, this book is essential reading for anyone doing systematic reviews. David Gough is Professor of Evidence Informed Policy and Practice and Director of SSRU and its EPPI-Centre and Co-Editor of the journal Evidence & Policy. Sandy Oliver is Professor of Public Policy and Deputy Director of SSRU and its EPPI-Centre. James Thomas is Reader in Social Policy, Assistant Director of SSRU and Associate Direcctor of the EPPI-Centre.
Author: Mark Petticrew
Publisher: John Wiley & Sons
ISBN: 1405150149
Category : Psychology
Languages : en
Pages : 352
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Book Description
Such diverse thinkers as Lao-Tze, Confucius, and U.S. Defense Secretary Donald Rumsfeld have all pointed out that we need to be able to tell the difference between real and assumed knowledge. The systematic review is a scientific tool that can help with this difficult task. It can help, for example, with appraising, summarising, and communicating the results and implications of otherwise unmanageable quantities of data. This book, written by two highly-respected social scientists, provides an overview of systematic literature review methods: Outlining the rationale and methods of systematic reviews; Giving worked examples from social science and other fields; Applying the practice to all social science disciplines; It requires no previous knowledge, but takes the reader through the process stage by stage; Drawing on examples from such diverse fields as psychology, criminology, education, transport, social welfare, public health, and housing and urban policy, among others. Including detailed sections on assessing the quality of both quantitative, and qualitative research; searching for evidence in the social sciences; meta-analytic and other methods of evidence synthesis; publication bias; heterogeneity; and approaches to dissemination.
Author: Steven Piantadosi
Publisher: Springer Nature
ISBN: 3319526367
Category : Medical
Languages : en
Pages : 2573
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Book Description
This is a comprehensive major reference work for our SpringerReference program covering clinical trials. Although the core of the Work will focus on the design, analysis, and interpretation of scientific data from clinical trials, a broad spectrum of clinical trial application areas will be covered in detail. This is an important time to develop such a Work, as drug safety and efficacy emphasizes the Clinical Trials process. Because of an immense and growing international disease burden, pharmaceutical and biotechnology companies continue to develop new drugs. Clinical trials have also become extremely globalized in the past 15 years, with over 225,000 international trials ongoing at this point in time. Principles in Practice of Clinical Trials is truly an interdisciplinary that will be divided into the following areas: 1) Clinical Trials Basic Perspectives 2) Regulation and Oversight 3) Basic Trial Designs 4) Advanced Trial Designs 5) Analysis 6) Trial Publication 7) Topics Related Specific Populations and Legal Aspects of Clinical Trials The Work is designed to be comprised of 175 chapters and approximately 2500 pages. The Work will be oriented like many of our SpringerReference Handbooks, presenting detailed and comprehensive expository chapters on broad subjects. The Editors are major figures in the field of clinical trials, and both have written textbooks on the topic. There will also be a slate of 7-8 renowned associate editors that will edit individual sections of the Reference.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309164257
Category : Medical
Languages : en
Pages : 267
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Book Description
Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.
Author: Cheryl Holly, EdD, RN, ANEF, FNAP
Publisher: Springer Publishing Company
ISBN: 0826131867
Category : Medical
Languages : en
Pages : 500
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Book Description
First Edition a 2013 Doody’s Core Title and AJN Book of the Year Award Winner! This text provides top-tier guidance for DNP students, graduate faculty, APRNs and other healthcare providers on how to use available research for improving patient outcomes and reducing costs. It is the only resource written expressly to meet the objectives of DNP courses. This second edition is completely updated and features three new approaches—umbrella reviews, mixed method reviews, and other types of reviews--for seeking, synthesizing, and interpreting available evidence to improve the delivery of patient care. The text also includes two new examples of completed systematic reviews and two completed proposals. The book presents, clearly and comprehensively, the knowledge and skills necessary to conduct a foundational comprehensive systematic review (CSR). It encompasses the complexities of the entire process, from asking clinical questions to getting the evidence into practice. The text includes question-specific methods and analysis and compares CSR methods, literature reviews, integrated reviews, and meta-studies. It describes how to find and appraise relevant studies, including the non-published “grey” literature and criteria for selecting or excluding studies, and describes how to use the results in practice. Also examined are ways to disemminate findings to benefit clinical practice and support best practices, and how to write a CSR proposal, final report and a policy brief based on systematic review findings. Plentiful examples, including two completed proposals and two completed systematic reviews, demonstrate every step of the process. An expanded resource chapter that can serve as a toolkit for conducting a systematic review is also provided. The text also covers useful software and includes objectives, summary points, end-of-chapter exercises, suggested readings and references. New to the Second Edition: • Three new chapters presenting new systematic review approaches: umbrella reviews, mixed method reviews, and other types of reviews including rapid and scoping reviews and reviews of text and opinoin • Two new examples of completed systematic reviews • Completely updated content throughout • Detailed information to foster systematic review research question development, efficient literature searches, and management of references Key Features: • Delivers the knowledge and skills necessary to conduct a CSR from start to finish • Serves as the only CSR resource written expressly for the advanced practice nurse • Describes useful software for conducting a systematic review • Provides rich examples including two completed CSRs • Includes objectives, summary points, end-of-chapter exercises, suggested readings and references • Provides a comprehensive toolkit of resources to complete a systematic review
