Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309452058
Category : Science
Languages : en
Pages : 231
Book Description
Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.
Preparing for Future Products of Biotechnology
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309452058
Category : Science
Languages : en
Pages : 231
Book Description
Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.
Publisher: National Academies Press
ISBN: 0309452058
Category : Science
Languages : en
Pages : 231
Book Description
Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.
Biotechnology
Author: Frederick B. Rudolph, Ph.D.
Publisher: Joseph Henry Press
ISBN: 0309596505
Category : Science
Languages : en
Pages : 296
Book Description
Biotechnology-the manipulation of the basic building blocks of life-is rapidly advancing in laboratories around the world. It has become routine to refer to DNA fingerprints and genetically engineered foods. Yet the "how to" of biotechnology is only the beginning. For every report of new therapies or better ways to produce food, there is a Jurassic Park scenario to remind us of the potential pitfalls. Biotechnology raises serious issues for scientists and nonscientists alike: Who will decide what is safe? Who will have access to our personal genetic information? What are the risks when advanced science becomes big business? In Biotechnology, experts from science, law, industry, and government explore a cross-section of emerging issues. This book offers straightforward explanations of basic science and provides insight into the serious social questions raised by these findings. The discussions explore five key areas: The state of the art in biotechnology-including an overview of the genetic revolution, the development of recombinant DNA technology, and the possibilities for applying the new techniques. Potential benefits to medicine and the environment-including gene therapy, the emerging area of tissue engineering and biomaterials, and the development of therapeutic proteins. Issues in technology transfer-focusing on the sometimes controversial relationship between university research centers and industry. Ethics, behavior, and values-exploring the ethical issues that surround basic research and applications of new technology, with a discussion of scientific misconduct and a penetrating look at the social impact of genetic discoveries. Government's role-including a comparison of U.S., European, and Japanese policies on pharmaceutical and biotechnology development. Biotechnology is here to stay, and this volume adds immeasurably to understanding its multiple aspects and far-reaching implications. This book will be of interest to scientists and industry leaders involved in biotechnology issues-and it will be welcomed by the concerned lay reader. Frederick B. Rudolph, Ph.D., is a professor of biochemistry and cell biology at Rice University and is executive director of the Institute of Biosciences and Bioengineering. Larry V. McIntire, Ph.D., is the E. D. Butcher Professor of Chemical and Biomedical Engineering at Rice University and is chair of the Institute of Biosciences and Bioengineering.
Publisher: Joseph Henry Press
ISBN: 0309596505
Category : Science
Languages : en
Pages : 296
Book Description
Biotechnology-the manipulation of the basic building blocks of life-is rapidly advancing in laboratories around the world. It has become routine to refer to DNA fingerprints and genetically engineered foods. Yet the "how to" of biotechnology is only the beginning. For every report of new therapies or better ways to produce food, there is a Jurassic Park scenario to remind us of the potential pitfalls. Biotechnology raises serious issues for scientists and nonscientists alike: Who will decide what is safe? Who will have access to our personal genetic information? What are the risks when advanced science becomes big business? In Biotechnology, experts from science, law, industry, and government explore a cross-section of emerging issues. This book offers straightforward explanations of basic science and provides insight into the serious social questions raised by these findings. The discussions explore five key areas: The state of the art in biotechnology-including an overview of the genetic revolution, the development of recombinant DNA technology, and the possibilities for applying the new techniques. Potential benefits to medicine and the environment-including gene therapy, the emerging area of tissue engineering and biomaterials, and the development of therapeutic proteins. Issues in technology transfer-focusing on the sometimes controversial relationship between university research centers and industry. Ethics, behavior, and values-exploring the ethical issues that surround basic research and applications of new technology, with a discussion of scientific misconduct and a penetrating look at the social impact of genetic discoveries. Government's role-including a comparison of U.S., European, and Japanese policies on pharmaceutical and biotechnology development. Biotechnology is here to stay, and this volume adds immeasurably to understanding its multiple aspects and far-reaching implications. This book will be of interest to scientists and industry leaders involved in biotechnology issues-and it will be welcomed by the concerned lay reader. Frederick B. Rudolph, Ph.D., is a professor of biochemistry and cell biology at Rice University and is executive director of the Institute of Biosciences and Bioengineering. Larry V. McIntire, Ph.D., is the E. D. Butcher Professor of Chemical and Biomedical Engineering at Rice University and is chair of the Institute of Biosciences and Bioengineering.
Preparing for Future Products of Biotechnology
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309452082
Category : Science
Languages : en
Pages : 231
Book Description
Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.
Publisher: National Academies Press
ISBN: 0309452082
Category : Science
Languages : en
Pages : 231
Book Description
Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.
Forest Health and Biotechnology
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309482887
Category : Science
Languages : en
Pages : 241
Book Description
The American chestnut, whitebark pine, and several species of ash in the eastern United States are just a few of the North American tree species that have been functionally lost or are in jeopardy of being lost due to outbreaks of pathogens and insect pests. New pressures in this century are putting even more trees at risk. Expanded human mobility and global trade are providing pathways for the introduction of nonnative pests for which native tree species may lack resistance. At the same time, climate change is extending the geographic range of both native and nonnative pest species. Biotechnology has the potential to help mitigate threats to North American forests from insects and pathogens through the introduction of pest-resistant traits to forest trees. However, challenges remain: the genetic mechanisms that underlie trees' resistance to pests are poorly understood; the complexity of tree genomes makes incorporating genetic changes a slow and difficult task; and there is a lack of information on the effects of releasing new genotypes into the environment. Forest Health and Biotechnology examines the potential use of biotechnology for mitigating threats to forest tree health and identifies the ecological, economic, and social implications of deploying biotechnology in forests. This report also develops a research agenda to address knowledge gaps about the application of the technology.
Publisher: National Academies Press
ISBN: 0309482887
Category : Science
Languages : en
Pages : 241
Book Description
The American chestnut, whitebark pine, and several species of ash in the eastern United States are just a few of the North American tree species that have been functionally lost or are in jeopardy of being lost due to outbreaks of pathogens and insect pests. New pressures in this century are putting even more trees at risk. Expanded human mobility and global trade are providing pathways for the introduction of nonnative pests for which native tree species may lack resistance. At the same time, climate change is extending the geographic range of both native and nonnative pest species. Biotechnology has the potential to help mitigate threats to North American forests from insects and pathogens through the introduction of pest-resistant traits to forest trees. However, challenges remain: the genetic mechanisms that underlie trees' resistance to pests are poorly understood; the complexity of tree genomes makes incorporating genetic changes a slow and difficult task; and there is a lack of information on the effects of releasing new genotypes into the environment. Forest Health and Biotechnology examines the potential use of biotechnology for mitigating threats to forest tree health and identifies the ecological, economic, and social implications of deploying biotechnology in forests. This report also develops a research agenda to address knowledge gaps about the application of the technology.
Career Opportunities in Biotechnology and Drug Development
Author: Toby Freedman
Publisher: CSHL Press
ISBN: 0879697253
Category : Biotechnology
Languages : en
Pages : 408
Book Description
An essential guide for students in the life sciences, established researchers, and career counselors, this resource features discussions of job security, future trends, and potential career paths. Even those already working in the industry will find helpful information on how to take advantage of opportunities within their own companies and elsewhere.
Publisher: CSHL Press
ISBN: 0879697253
Category : Biotechnology
Languages : en
Pages : 408
Book Description
An essential guide for students in the life sciences, established researchers, and career counselors, this resource features discussions of job security, future trends, and potential career paths. Even those already working in the industry will find helpful information on how to take advantage of opportunities within their own companies and elsewhere.
Genetically Engineered Crops
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309437385
Category : Science
Languages : en
Pages : 607
Book Description
Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human health, the environment, and ethical considerations. At the same time, others are concerned that the technology is not reaching its potential to improve human health and the environment because of stringent regulations and reduced public funding to develop products offering more benefits to society. While the debate about these and other questions related to the genetic engineering techniques of the first 20 years goes on, emerging genetic-engineering technologies are adding new complexities to the conversation. Genetically Engineered Crops builds on previous related Academies reports published between 1987 and 2010 by undertaking a retrospective examination of the purported positive and adverse effects of GE crops and to anticipate what emerging genetic-engineering technologies hold for the future. This report indicates where there are uncertainties about the economic, agronomic, health, safety, or other impacts of GE crops and food, and makes recommendations to fill gaps in safety assessments, increase regulatory clarity, and improve innovations in and access to GE technology.
Publisher: National Academies Press
ISBN: 0309437385
Category : Science
Languages : en
Pages : 607
Book Description
Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human health, the environment, and ethical considerations. At the same time, others are concerned that the technology is not reaching its potential to improve human health and the environment because of stringent regulations and reduced public funding to develop products offering more benefits to society. While the debate about these and other questions related to the genetic engineering techniques of the first 20 years goes on, emerging genetic-engineering technologies are adding new complexities to the conversation. Genetically Engineered Crops builds on previous related Academies reports published between 1987 and 2010 by undertaking a retrospective examination of the purported positive and adverse effects of GE crops and to anticipate what emerging genetic-engineering technologies hold for the future. This report indicates where there are uncertainties about the economic, agronomic, health, safety, or other impacts of GE crops and food, and makes recommendations to fill gaps in safety assessments, increase regulatory clarity, and improve innovations in and access to GE technology.
Gene Drives on the Horizon
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309437873
Category : Science
Languages : en
Pages : 231
Book Description
Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.
Publisher: National Academies Press
ISBN: 0309437873
Category : Science
Languages : en
Pages : 231
Book Description
Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.
Animal Biotechnology
Author: National Research Council
Publisher: National Academies Press
ISBN: 030916933X
Category : Technology & Engineering
Languages : en
Pages : 200
Book Description
Genetic-based animal biotechnology has produced new food and pharmaceutical products and promises many more advances to benefit humankind. These exciting prospects are accompanied by considerable unease, however, about matters such as safety and ethics. This book identifies science-based and policy-related concerns about animal biotechnologyâ€"key issues that must be resolved before the new breakthroughs can reach their potential. The book includes a short history of the field and provides understandable definitions of terms like cloning. Looking at technologies on the near horizon, the authors discuss what we know and what we fear about their effectsâ€"the inadvertent release of dangerous microorganisms, the safety of products derived from biotechnology, the impact of genetically engineered animals on their environment. In addition to these concerns, the book explores animal welfare concerns, and our societal and institutional capacity to manage and regulate the technology and its products. This accessible volume will be important to everyone interested in the implications of the use of animal biotechnology.
Publisher: National Academies Press
ISBN: 030916933X
Category : Technology & Engineering
Languages : en
Pages : 200
Book Description
Genetic-based animal biotechnology has produced new food and pharmaceutical products and promises many more advances to benefit humankind. These exciting prospects are accompanied by considerable unease, however, about matters such as safety and ethics. This book identifies science-based and policy-related concerns about animal biotechnologyâ€"key issues that must be resolved before the new breakthroughs can reach their potential. The book includes a short history of the field and provides understandable definitions of terms like cloning. Looking at technologies on the near horizon, the authors discuss what we know and what we fear about their effectsâ€"the inadvertent release of dangerous microorganisms, the safety of products derived from biotechnology, the impact of genetically engineered animals on their environment. In addition to these concerns, the book explores animal welfare concerns, and our societal and institutional capacity to manage and regulate the technology and its products. This accessible volume will be important to everyone interested in the implications of the use of animal biotechnology.
Academia to Biotechnology
Author: Jeffrey M Gimble
Publisher: Elsevier
ISBN: 0080493157
Category : Medical
Languages : en
Pages : 187
Book Description
Academia to Biotechnology deals with both the abstract and practical aspects of moving from a univerisity laboratory to a position in the biotech industry. Each chapter lists common and unique features to evaluate breaking down complex decisions into manageable elements. Several sections provide "how to" guides for the preparation of manuscripts, patents, grants, and internal company documents. - Written by an experienced academician and successful biotechnology entrepreneur - Reviews the basic tools taught in a traditional university - Identifies new ways these these tools will be used in the corporate world - Details the 'nuts and bolts' necessary to negotiate a successful position in the biotech industry
Publisher: Elsevier
ISBN: 0080493157
Category : Medical
Languages : en
Pages : 187
Book Description
Academia to Biotechnology deals with both the abstract and practical aspects of moving from a univerisity laboratory to a position in the biotech industry. Each chapter lists common and unique features to evaluate breaking down complex decisions into manageable elements. Several sections provide "how to" guides for the preparation of manuscripts, patents, grants, and internal company documents. - Written by an experienced academician and successful biotechnology entrepreneur - Reviews the basic tools taught in a traditional university - Identifies new ways these these tools will be used in the corporate world - Details the 'nuts and bolts' necessary to negotiate a successful position in the biotech industry
Pharmaceutical Biotechnology
Author: Oliver Kayser
Publisher: John Wiley & Sons
ISBN: 3527329943
Category : Science
Languages : en
Pages : 677
Book Description
This second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations. With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.
Publisher: John Wiley & Sons
ISBN: 3527329943
Category : Science
Languages : en
Pages : 677
Book Description
This second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations. With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.