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Author: P.N. Rao
Publisher: Elsevier
ISBN: 0323152155
Category : Science
Languages : en
Pages : 400
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Book Description
Premature Chromosome Condensation: Application in Basic, Clinical, and Mutation Research emerged from a workshop supported by the International Union against Cancer that reviewed the status of research on premature chromosome condensation and explored future possibilities, not least in relation to cancer. The workshop was held at the Institut für Humangenetik, Freie Universität Berlin, on September 6, 1980. The book begins with a review of the process of premature chromosome condensation. This is followed by separate chapters on the functional and morphological aspects of premature chromosome condensation; the behavior of prematurely condensed chromosomes (PCC) during mitosis in binucleate and multinucleate cells; chromosomes from spermatogenic cells; and micronucleus-derived PCC. Subsequent chapters discuss the application of banding techniques to the study of PCC; the factors involved in the condensation of interphase chromatin into chromosomes; and the induction of premature chromosome condensation in somatic plant cells. This book will be helpful to readers working in basic and applied research or in teaching. These include cytogeneticists, cell biologists, biochemists, and investigators in the field of mutation research.
Author: P.N. Rao
Publisher: Elsevier
ISBN: 0323152155
Category : Science
Languages : en
Pages : 400
Get Book Here
Book Description
Premature Chromosome Condensation: Application in Basic, Clinical, and Mutation Research emerged from a workshop supported by the International Union against Cancer that reviewed the status of research on premature chromosome condensation and explored future possibilities, not least in relation to cancer. The workshop was held at the Institut für Humangenetik, Freie Universität Berlin, on September 6, 1980. The book begins with a review of the process of premature chromosome condensation. This is followed by separate chapters on the functional and morphological aspects of premature chromosome condensation; the behavior of prematurely condensed chromosomes (PCC) during mitosis in binucleate and multinucleate cells; chromosomes from spermatogenic cells; and micronucleus-derived PCC. Subsequent chapters discuss the application of banding techniques to the study of PCC; the factors involved in the condensation of interphase chromatin into chromosomes; and the induction of premature chromosome condensation in somatic plant cells. This book will be helpful to readers working in basic and applied research or in teaching. These include cytogeneticists, cell biologists, biochemists, and investigators in the field of mutation research.
Author: G. Obe
Publisher: Springer Science & Business Media
ISBN: 3642695302
Category : Science
Languages : en
Pages : 338
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Book Description
This year we remember the 39th anniversary of the atomic bomb explo sions in Hiroshima and Nagasaki, which led to the exposure of thou sands of people to high doses of ionizing radiations. Nearly 18 years earlier, on the 15th of September, 1927, H. J. Muller presented his paper The Problem of Genic Modification at the Fifth International Congress of Genetics in Berlin, in which he brilliantly demonstrated the muta genic activity of X-rays. In 1928, K. H. Bauer formulated his mutation theory of the origin of cancer, and already in 1914, Th. Boveri speculat ed that tumor cells originate from an abnormal chromosomal comple ment. In the meantime we have learned that also nonionizing radiation and an immense number of environmental chemicals, both, man-made and naturally occurring, are mutagenic in a variety of test systems, in cluding human cells. In no case has it been shown unequivocally that physical or chemical mutagens have led to an elevation of the mutation rate in the germ cells of man, but in view of the huge body of experi mental data this seems to be a problem of detection. It can be expect ed that germ cell mutations are induced as a consequence of exposure to mutagens in man, as yet undetectable with the methods at hand. An uncontrolled addition of mutations to the human gene pool may well have unforeseen and catastrophic consequences in future genera tions for whom we should feel responsible.
Author: Friedrich Vogel
Publisher: Springer Science & Business Media
ISBN: 3662024896
Category : Medical
Languages : en
Pages : 842
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Book Description
The first edition of this book, published in 1979, was found useful by many stu dents and was well received by the scientific community. Since the book was first written, human genetics has undergone dramatic developments, mainly due to the introduction of new concepts and techniques from molecular biology. Con comitantly, "basic" scientists have become increasingly interested in problems of human genetics. More than 700 human genes have been mapped, genes of previ ously unsuspected complexity -such as the gene for factor VIII - have become known, and the structure of noncoding DNA sequences is being analyzed with the aim of understanding gene regulation. DNA diagnosis is being rapidly intro duced into medical genetics. All this, as well as the extensive progress in most other fields of human and medical genetics, had to be considered in the prepara tion of this second edition. The book has been extensively revised and rewritten. A substantial new section dealing with gene and chromosomal structure at the molecular level has been added. The newer knowledge of molecular genetics has been incorporated, and the conceptual and practical contribution of DNA methods (for example in the hemoglobinopathies and in some other diseases) is discussed. Many new figures and tables have been added, and some illustrative material has been replaced. We have read carefully the many friendly and sometimes flattering reviews of the first edition.
Author: Peter M. Wiedemann
Publisher: John Wiley & Sons
ISBN: 9783527320486
Category : Business & Economics
Languages : en
Pages : 248
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Book Description
One of the few books to focus on the critical problem of the correct characterization of conflicting data for an adequate risk evaluation, this title comprehensively covers the different approaches in various research areas in the US and in Europe, while also considering the ethical implications of risk evaluation. In addition, special attention is paid to the sensitive topic of potential health risks through electromagnetic fields. Written by leading experts in the field, this is an indispensable resource for policy makers and professionals in health risk assessment.
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1442
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Book Description
First multi-year cumulation covers six years: 1965-70.
Author: Kenneth Giles
Publisher: Springer Science & Business Media
ISBN: 1468443798
Category : Science
Languages : en
Pages : 485
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Book Description
The current and potential importance of plant tissue culture techniques in crop improvement is hard to overemphasize. There are few areas where these techniques will have more possible im pact than in tropical agriculture, where the availability of high productivity varieties is sadly lacking in many species. The potential for the rapid, clonal propagation of elite individuals and the use of controlled multiline planting could have a major effect on crop yield and disease resistance in many areas of the world. This volume is a collection of papers presented at the Con ference on "Crop Improvement Through Tissue Culture", held at the Base Institute, Calcutta, India in December 1981. It attempts to bring together local research workers, familiar with the agri cultural resources of the area and tissue culture and molecular 4 level workers. It was the hope of the conference that the "cross fertilization" of ideas would lead to new approaches and activity in this area. The editors trust that this collection of papers will stimu~ late interest and research in the tissue culture and improvement of crop plants everywhere. v ACKNOWLEDGEMENTS The symposium from which the papers in this book are drawn was held at Bose Institute, Calcutta on December 6 to December 10, 1981.
Author: Robert A. Schlegel
Publisher: Elsevier
ISBN: 1483272702
Category : Science
Languages : en
Pages : 390
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Book Description
Molecular Regulation of Nuclear Events in Mitosis and Meiosis presents papers from researchers in various fields engaged in the scientific study of molecular mechanisms involved in the control of nuclear events in meiotic and mitotic cell activity. Various articles in the book discuss a wide range of topics such as the development of cytoplasmic activities that control chromosome cycles during maturation of amphibian oocytes; dynamics of the nuclear lamina during mitosis and meiosis; role of protein phosphorylation in xenopus oocyte meiotic maturation; and cell cycle studies of histone modifications. Molecular and cell biologists, oncologists, and biochemists will find the book invaluable.
Author: Günter Obe
Publisher: Springer Science & Business Media
ISBN: 3540714146
Category : Science
Languages : en
Pages : 526
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Book Description
The book helps the reader to better understand cytogenetics and the intricacies of the methodology. The different methods of fluorescence in situ hybridization are discussed and the results achieved are presented. The book provides a comprehensive review of basic and applied aspects of cytogenetics and thus is of intense interest to all those interested in chromosomes and their alterations by different types of mutagens, including chemical mutagens and ionizing and nonionizing radiation, with special reference to electromagnetic fields.
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1184
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Book Description
Author: Alton L. Boynton
Publisher: Elsevier
ISBN: 1483277410
Category : Science
Languages : en
Pages : 576
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Book Description
Control of Animal Cell Proliferation, Volume I presents how animals regulate their proliferation activity and how cells become proliferatively autonomous resulting in malignant behavior. This book provides an understanding of mechanisms that control animal cell proliferation. Organized into five parts encompassing 17 chapters, this volume begins with an overview of the efforts to elucidate he genetic alterations that lead normal cells to become cancer cells, which have been aided considerably by the investigation of acute retroviruses. This text then examines the factors involved in growth control. Other chapters describe in detail the biology and biochemistry of epidermal growth factor (EGF), which have been elucidated through the study of cultured human fibroblasts. This book discusses as well the protein kinases with specificity for tyrosine. The final chapter deals with regulation of initiation of eukaryotic protein synthesis by phosphorylation. This book is a valuable resource for scientists as well as cellular and molecular biologists.
