Predicting Individual Responses to Exercise Interventions PDF Download
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Author: Vassilis Mougios
Publisher: Frontiers Media SA
ISBN: 2889664635
Category : Science
Languages : en
Pages : 179
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Book Description
Author: Vassilis Mougios
Publisher: Frontiers Media SA
ISBN: 2889664635
Category : Science
Languages : en
Pages : 179
Get Book Here
Book Description
Author: Stephen S. Senn
Publisher: John Wiley & Sons
ISBN: 0470854588
Category : Mathematics
Languages : en
Pages : 364
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Book Description
Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages. * Comprehensive coverage of the design and analysis of cross-over trials. * Each technique is carefully explained and the mathematics is kept to a minimum. * Features many real and original examples, taken from the author's vast experience. * Includes discussion of analysis using SAS, S-Plus and, GenStat, StatXact and Excel. * Written in a style suitable for statisticians and physicians alike. * Computer programs to accompany the examples in the book can be downloaded from the Web Primarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics.
Author: Alain Zuur
Publisher: Springer
ISBN: 0387459723
Category : Science
Languages : en
Pages : 686
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Book Description
This book provides a practical introduction to analyzing ecological data using real data sets. The first part gives a largely non-mathematical introduction to data exploration, univariate methods (including GAM and mixed modeling techniques), multivariate analysis, time series analysis, and spatial statistics. The second part provides 17 case studies. The case studies include topics ranging from terrestrial ecology to marine biology and can be used as a template for a reader’s own data analysis. Data from all case studies are available from www.highstat.com. Guidance on software is provided in the book.
Author: Trisha Greenhalgh
Publisher: John Wiley & Sons
ISBN: 111948474X
Category : Medical
Languages : en
Pages : 290
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Book Description
Required reading in many medical and healthcare institutions, How to Read a Paper is a clear and wide-ranging introduction to evidence-based medicine and healthcare, helping readers to understand its central principles, critically evaluate published data, and implement the results in practical settings. Author Trisha Greenhalgh guides readers through each fundamental step of inquiry, from searching the literature to assessing methodological quality and appraising statistics. How to Read a Paper addresses the common criticisms of evidence-based healthcare, dispelling many of its myths and misconceptions, while providing a pragmatic framework for testing the validity of healthcare literature. Now in its sixth edition, this informative text includes new and expanded discussions of study bias, political interference in published reports, medical statistics, big data and more. Offers user-friendly guidance on evidence-based healthcare that is applicable to both experienced and novice readers Authored by an internationally recognised practitioner and researcher in evidence-based healthcare and primary care Includes updated references, additional figures, improved checklists and more How to Read a Paper is an ideal resource for healthcare students, practitioners and anyone seeking an accessible introduction to evidence-based healthcare.
Author: Michel Neidhart
Publisher: Academic Press
ISBN: 0127999205
Category : Science
Languages : en
Pages : 546
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Book Description
DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also discussed as a plasma and serum test for non-invasive screening, diagnostic and prognostic tests, as compared to biopsy-driven gene expression analysis, factors which have led to the use of DNA methylation as a potential tool for determining cancer risk, and diagnosis between benign and malignant disease. Therapies are at the heart of this volume and the possibilities of DNA demethylation. In cancer, unlike genetic mutations, DNA methylation and histone modifications are reversible and thus have shown great potential in the race for effective treatments. In addition, the authors present the importance of high-throughput methylome analysis, not only in cancer, but also in non-neoplastic diseases such as rheumatoid arthritis. - Discusses breaking biomarker research in major disease families of current health concern and research interest, including obesity, type II diabetes, schizophrenia, and autoimmunity - Summarizes advances not only relevant to cancer, but also in non-neoplastic disease, currently an emerging field - Describes wholly new concepts, including the linking of metabolic pathways with epigenetics - Provides translational researchers with the knowledge of both basic research and clinic applications of DNA methylation in human diseases
Author: James M. Rippe
Publisher: CRC Press
ISBN: 104001626X
Category : Medical
Languages : en
Pages : 1495
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Book Description
The fourth edition of Dr. James Rippe’s classic Lifestyle Medicine textbook continues to lead and inform the rapidly growing field of lifestyle medicine. This is the discipline that focuses on the impact of daily habits and actions on both short- and long-term health and quality of life. The first edition of this comprehensive work named the field of lifestyle medicine in the academic medical literature. The fourth edition continues to span and expand the field and offers extensive evidence-based literature in virtually every aspect of lifestyle medicine. This Textbook, edited by cardiologist Dr. James Rippe, who is a leading lifestyle medicine researcher, represents the combined wisdom and recommendations of over 325 experts in virtually every aspect of lifestyle medicine. Chapter authors have been chosen because of their background as leaders in various aspects of lifestyle medicine. Lifestyle Medicine, Fourth Edition contains extensive sections on the treatment and prevention of coronary heart disease,stroke, cancer, diabetes, obesity, substance abuse, dementia, and many other clinical conditions. Key lifestyle modalities such as physical activity, nutrition, weight management, sleep, stress reduction, and positive connections with other humans are supported by detailed discussion and state-of-the-art evidence. The expanded section on behavioral medicine provides an important framework for these discussions. Every chapter has been completely revised and many new topics added, such as lifestyle medicine for nursing, psychiatry, and preventive neurology. The fourth edition of this classic text continues to serve as the leading, comprehensive textbook in lifestyle medicine. The original has been called the “indispensable bible” of lifestyle medicine, and the fourth edition of this work continues to justify this designation. There is no longer any serious doubt that daily habits and actions have a significant impact on multiple aspects of health. The fourth edition of Lifestyle Medicine provides the scientific evidence to support this assertion and will serve as an invaluable reference and guide, not only to lifestyle medicine practitioners but to all primary care physicians, subspecialty physicians, nurses, and other healthcare practitioners.
Author: Martin S. Hagger
Publisher: Cambridge University Press
ISBN: 1108750117
Category : Psychology
Languages : en
Pages : 730
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Book Description
Social problems in many domains, including health, education, social relationships, and the workplace, have their origins in human behavior. The documented links between behavior and social problems have compelled governments and organizations to prioritize and mobilize efforts to develop effective, evidence-based means to promote adaptive behavior change. In recognition of this impetus, The Handbook of Behavior Change provides comprehensive coverage of contemporary theory, research, and practice on behavior change. It summarizes current evidence-based approaches to behavior change in chapters authored by leading theorists, researchers, and practitioners from multiple disciplines, including psychology, sociology, behavioral science, economics, philosophy, and implementation science. It is the go-to resource for researchers, students, practitioners, and policy makers looking for current knowledge on behavior change and guidance on how to develop effective interventions to change behavior.
Author: Mauro Moscucci
Publisher: Lippincott Williams & Wilkins
ISBN: 1496399293
Category : Medical
Languages : en
Pages : 992
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Book Description
An easily accessible, ready reference for the entire cardiac team, Grossman & Baim’s Handbook of Cardiac Catheterization, Angiography, and Intervention is an essential resource in today’s cardiac catheterization lab. This practical handbook, edited by Dr. Mauro Moscucci with contributions from associate editor, Marc D. Feldman, follows the bestselling text, Grossman & Baim's Cardiac Catheterization, Angiography, and Intervention, providing fast, convenient access to authoritative information in a portable handbook format.
Author: Nick Draper
Publisher: Routledge
ISBN: 1315523833
Category : Health & Fitness
Languages : en
Pages : 613
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Book Description
Physical activity and its relationship to health is one of the great issues of our age. The causes of, and solutions to, physical inactivity are complex and multi-dimensional, and therefore the subject needs to be studied and understood from a variety of perspectives. This is the first textbook to provide a truly multi-disciplinary introduction to physical activity studies. Offering a complete foundation to the subject, it covers the basics of every core discipline from biochemistry, public health and biomechanics to physiology, sport psychology and sociology. It introduces a full range of topics across the physical activity curriculum, including behaviour change, motor skill development, nutrition, exercise prescription, public health policy, and physical education, providing a well-balanced and international perspective on each important issue. There is also a strong emphasis throughout the book on the practical, applied dimensions of physical activity, including innovative approaches to promotion and intervention tailored to every age range and environment. Physical Activity: A Multi-disciplinary Introduction is an indispensable companion to any course or degree programme with an emphasis on physical activity and health. A variety of exclusive eResources to aid teaching and learning are also available via the Routledge website.
Author: Christos Frantzidis
Publisher: Frontiers Media SA
ISBN: 2889661229
Category : Science
Languages : en
Pages : 577
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Book Description
Previous studies showed that both healthy and pathological aging are associated with changes in brain structure and function of the mature human brain. The most prominent anatomical alteration are changes in prefrontal cortex morphology, volume loss and reduced white-matter integrity and hippocampal atrophy. Cognitive decline affects mainly the performance of episodic memory, speed of sensory information processing, working memory, inhibitory function and long-term memory. It has been also proposed that due to the aforementioned changes the aging brain engages in compensatory brain mechanism such as a broader activation of cortical regions (mainly frontal) rather than specialized activation. Evidence suggests that similar changes occur with pathological aging but to a greater extent. In this case information flow is disrupted due to neurodegeneration, functional activation of posterior (occipito-temporal) regions is decreased and as a consequence the brain fails to process sensorial input in the ventral pathway and cognitive deficits appear. In the last years, functional alterations associated with aging have been studied using the mathematical notion of graph theory that offers an integrative approach since it examines different properties of the brain network: 1) Organization level 2) amount of local information processing, 3) information flow 4) cortical community structure and 5) identification of functional / anatomical hubs. So, graph theory offers an attractive way to model brain networks organization and to quantify their pathological deviations. Previous studies have already employed this mathematical notion and demonstrated that age-related neurodegeneration is often accompanied by loss of optimal network organization either due to diminished local information processing or due to progressive isolation of distant brain regions. They have also found that changes in network properties may be present even in the preclinical phase, which could be taken as a biological marker of disease.
